Clinical trials: Induction Time
Healthy
Study of Ciraparantag for Reversal of Anticoagulation Induced by Edoxaban, Apixaban or Rivaroxaban in Healthy Adults
A randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of ciraparantag for reversal of anticoagulation induced by different anticoagulant drugs in generally healthy adults as measured primarily…
- Trial name
- NCT04593784
- Testing
- Ciraparantag, Point-of-Care Coagulometer (investigational device)
- Where
- 3 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- AMAG Pharmaceuticals, Inc.
Healthy
Real-time Monitoring of Motor Cortical Activity Induced by Low-frequency Repetitive Transcranial Magnetic Stimulation
In this study, we investigated the effect of low-frequency repetitive trans cranial magnetic stimulation, one of the noninvasive brain stimuli, on the functional changes of the bilateral motor cortical activity in normal subjects…
- Trial name
- NCT04019028
- Testing
- low frequency rTMS + Navigation System, only low frequency rTMS
- Where
- South Korea
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Erectile Dysfunction
The Pharmacological Basis for the Increase in Visual Time Constants Induced by Single Oral Doses of Sildenafil
Sildenafil and similar drugs have been used for several years to treat erectile dysfunction. It has been noticed that in some people, sildenafil causes a subtle increase in the length of time that visual images that we see are…
- Trial name
- NCT00463957
- Testing
- sildenafil, tadalafil
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Movement After Intravenous Cannulation
Optimum Time for Intravenous Cannulation After Induction With Sevoflurane in Pediatric Patient
This study aimed to determinate effective dose 95 (ED95) intravenous cannulation in pediatric patient after induction of sevoflurane 8 vol%
- Trial name
- NCT04284579
- Testing
- IV cannula
- Where
- Indonesia
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Parkinson Disease, MSA - Multiple System Atrophy
Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease
Clinical diagnosis of Parkinson's disease (PD), multiple system atrophy (MSA) and dementia with Lewy bodies (DLB) is challenging, especially in the early stages.
- Conditions
- Parkinson Disease, MSA - Multiple System Atrophy, Lewy Body Dementia (LBD), Neurodegenerative Disease
- Trial name
- EXTRAORDINARY (NCT06846658)
- Where
- 3 sites in Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Pain, Acute
Duration of Music Interventions and Pain Tolerance (DOMINANT)
This study will investigate the effect of different durations of music interventions (1, 5 and 20 minutes of music) on pain tolerance.
- Trial name
- DOMINANT (NCT06286137)
- Testing
- Listening to music for 1 minute, Listening to music for 5 minutes, Listening to music for 20 minutes
- Where
- Netherlands
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Intestinal Obstruction
Effects of Methylnaltrexone in Comparison to Naloxone on Loperamide-induced Delay of the Oro-cecal, Whole-gut and Colon Transit Time.
The purpose of this study is to describe the effects of repeated-dose methylnaltrexone in preventing loperamide-induced delay of whole-gut, oro-cecal and colon transit time and to measure pharmacokinetics of methylnaltrexone and…
- Trial name
- NCT01596764
- Testing
- Loperamide, Colon Transit, Sulfasalazine
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Exercise
Education Time Influence on Exercise-Induced Hypoalgesia
We will investigate the effects of the length of education on exercise-induced hypoalgesia (EIH). Two previous studies have shown that positive education about the effects of exercise and the phenomena of EIH produce enhancements…
- Trial name
- NCT05658224
- Testing
- Education on effects of Exercise-induced hypoalgesia from exercise
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of South Dakota
Cervical Ripening, Induction of Labor
Heated Saline in Cervical Balloon for Labor Induction, a RCT
This study is a single-center, randomized, two-arm, controlled trial, including women requiring cervical ripening during the process Induction of Labor using Balloon catheter (BC).
- Conditions
- Cervical Ripening, Induction of Labor, Unfavorable Cervix, Mechanical Method
- Trial name
- NCT05864326
- Testing
- Warm group, Room temperature group
- Where
- Switzerland
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Begona Martinez de Tejada
Medication Administered in Error, Medication Adverse Effects
Identifying Drug-related Problems at ED Triage (DRP-EDiT) V1
Up to a third of patients who visit emergency departments (EDs) do so because they have an issue with medicines prescribed by their doctor or purchased over the counter.
- Conditions
- Medication Administered in Error, Medication Adverse Effects, Medication Reaction
- Trial name
- DRP-EDiT (NCT05476705)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Hypotension on Induction
Carotid Artery Corrected Flow Time and Respiratory Variation of Blood Flow Peak Velocity for Prediction of Hypotension After Induction of General Anaesthesia in Adult Patients With Chronic Liver Disease
Baseline Measurements For the ultrasound parameters, it is the average of three readings In supine position . The investigators will continuously monitoring during induction and 10 minutes after.
- Trial name
- NCT07370103
- Where
- Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Opioid Overdose
Pharmacodynamic Evaluation of Intramuscular Nalmefene Autoinjector 1.5 mg Compared to Intranasal Narcan 4 mg
The purpose of this study is to determine the pharmacodynamics (change in minute ventilation) of nalmefene when given as an autoinjector intramuscularly (IM; into the thigh) compared to naloxone when given intranasally (IN; into…
- Trial name
- NCT06719986
- Testing
- Nalmefene HCl injection, Naloxone HCl intranasal
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Purdue Pharma LP
Glucose Metabolism, Hormonal Changes
Long Time Metabolic Changes Induced by Genetically Modified Potatoes
In this study the effects of genetically modified potatoes on the human metabolism will be observed. Healthy volunteers receive for one week muffins, produced with starch from a genetically modified potato or with a normal…
- Conditions
- Glucose Metabolism, Hormonal Changes, Satiety
- Trial name
- NCT00953602
- Testing
- Genetically modified potato
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Insomnia, Healthy Adult
The Impact of Acute Pain on Sleep Parameters in the Insomnia Population and Healthy Controls
This study investigates how acute exercise-induced muscular pain affects sleep quality and sleep architecture in people with insomnia compared to healthy sleepers.
- Conditions
- Insomnia, Healthy Adult, Sleep, Musculoskeletal Pain
- Trial name
- NCT07826650
- Testing
- Eccentric exercise
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Substance Dependence
To Investigate If Single Doses Of GSK618334 Are Safe And To Investigate Blood Levels Of GSK618334
GSK618334 is being developed as an innovative treatment for substance dependence and potentially other compulsive behavioral disorders.
- Trial name
- NCT00513279
- Testing
- GSK618334
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN)
Beyond the Mehran Risk Score: Predictive Value of Total Ischemic Time for Contrast-Induced Nephropathy in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.
Contrast-Induced Nephropathy (CIN) is a serious complication following primary percutaneous coronary intervention (PCI) in patients presenting with acute ST-segment elevation myocardial infarction (STEMI).
- Conditions
- ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN), Acute Kidney Injury
- Trial name
- NCT07826572
- Testing
- Total Ischemic Time Evaluation
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Reflexology, Labor Induction
The Effect of Reflexology on Time to Delivery During Induction of Labor
This prospective, randomized controlled trial evaluates the effect of reflexology on maternal anxiety, labor duration, and pain in women undergoing labor induction with an extra-amniotic balloon (EAB).
- Conditions
- Reflexology, Labor Induction, Extra Amniotic Balloon
- Trial name
- NCT07168187
- Testing
- Reflexology
- Where
- Israel
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Alcohol Abuse
Personal Values and Mandated Students
This study aims to examine the efficacy of an enhanced alcohol intervention among individuals who are mandated to complete an alcohol education activity as part of a university sanction.
- Trial name
- NCT03247647
- Testing
- Enhanced Intervention, Standard Intervention
- Where
- 2 sites in United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Brown University
Induction of Labor Affected Fetus / Newborn
Castor Oil Ingestion and Balloon Catheter for Labor Induction in Nulliparous
The goal of this randomized controlled trial is to examine the efficacy of combining castor oil ingestion with extra-amniotic single balloon catheter for cervical ripening on time from induction to delivery in nulliparous women.
- Trial name
- NCT06325007
- Testing
- Induction of labor
- Where
- 2 sites in Israel
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Holy Family Hospital, Nazareth, Israel
Intestinal Obstruction
Effects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy Subjects
The purpose of this study is to describe the effects of methylnaltrexone in preventing loperamide-induced delay of the oro-cecal and whole-gut transit time and measure pharmacokinetics of methylnaltrexone after subcutaneous and…
- Trial name
- LOP-MNTX-2009 (NCT01596777)
- Testing
- Loperamide, Methylnaltrexone 12 mg sc., Methylnaltrexone IR capsule
- Where
- Germany
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald