Clinical trials: Induction of Labor
Cervical Ripening and Induction of Labor
Comparison Between Vaginal Misoprostol Gel and Oral Misoprostol Solution in Induction of Labor
The goal of this clinical trial is to study the efficacy of vaginal versus oral misoprostol solution in cervical ripening for induction of labor.
- Trial name
- NCT06874049
- Testing
- Vaginal misoprostol, Oral misoprostol solution (OMS)
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hagar Muhammad Abdulfattah Muhammad
Hypertension, Premature Birth
Trial of Exercise to Prevent HypeRtension in Young Adults
TEPHRA investigates the effect of exercise on blood pressure and other cardiovascular factors in young adults with different birth histories.
- Trial name
- TEPHRA (NCT02723552)
- Testing
- Aerobic Exercise
- Where
- United Kingdom
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Healthy, Memory Impairment
The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers
The purpose of this study is to assess if ketamine will induce, in healthy volunteers, impairment of working memory and if the drug AZD8529 will block the effects of ketamine on working memory as assessed by functional magnetic…
- Trial name
- NCT00985933
- Testing
- AZD8529
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Preeclampsia, Severe Preeclampsia
First-trimester Prediction of Preeclampsia
Preeclampsia is a complication of pregnancy related to adverse maternal and neonatal outcomes, including fetal growth restriction and perinatal death.
- Conditions
- Preeclampsia, Severe Preeclampsia, Fetal Growth Restriction, Preterm Birth
- Trial name
- PREDICTION (NCT02189148)
- Where
- 4 sites in Canada
- Volunteers
- 7,554 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Labor (Obstetrics)--Complications
Uterocervical Angle Versus Cervical Length as a Predictor of Labor Induction in Term Singleton Pregnancy
Induction of labor is frequently performed in all obstetric clinics. Failed IOL has been defined in many different ways.Bishop scoring, which is a traditional and subjective method, is more frequently evaluated with cervical…
- Trial name
- NCT06558500
- Testing
- Uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Pregnancy
Sonoelastography of the Uterine Cervix Before Induction of Labor
The investigators aim to measure sonoelastographically the elasticity of the uterine cervix in pregnant patients at term before induction of labor and compare between patients with successful and failed inductions.
- Trial name
- SUCI (NCT02283606)
- Testing
- Accuvix SnonAce UGEO
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Induction of Labour, Labour, Induced
Misoprostol Labour Induction Study
Labour induction is a frequent obstetric intervention (~20%). Prostaglandins (PGs) are effective agents, but gastrointestinal (GI) intolerance has limited use to non-oral routes.
- Trial name
- NCT03489928
- Testing
- Oral Misoprostol, Vaginal Misoprostol, Dinoprostone
- Volunteers
- 511 people, healthy volunteers welcome
- Sponsor
- David Young
Labour,Induced
Oral Misoprostol Solution in Labor Induction
This study compares safety and efficacy between repetitive hourly dose of oral misoprostol and two hourly dose oral regimens for cervical ripening and labor induction.
- Trial name
- NCT03927807
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Induction of Labor Affected Fetus / Newborn
The Impact of a Customized Informative Video Prior to Induction of Labor on Anxiety Relieve.
To determine whether watching a personalized video prior to medically indicated labor induction among term parturients reduces anxiety levels according to the STAI questionnaire, compared to a standard counselling.
- Trial name
- NCT06375746
- Testing
- Personalized video
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Delivery Delayed
Nipple Stimulation for Labor Induction
This study will examine the use of nipple stimulation for cervical ripening in women who present to the labor and delivery ward after their water has broken but have a contraindication to prostaglandins.
- Trial name
- NCT03025503
- Testing
- nipple stimulation
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Premature Birth, Bronchopulmonary Dysplasia
Assessment of Lung Structure and Function of Infants Born Prematurely
The purpose of this study is to evaluate the growth of the lung and how easily gas can be taken up by the lung in healthy infants born at full term without any breathing problems and infants born prematurely.
- Conditions
- Premature Birth, Bronchopulmonary Dysplasia, Asthma
- Trial name
- NCT00422305
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Indiana University
Preterm Premature Rupture of Fetal Membranes, Induction of Labor Affected Fetus / Newborn
A Randomized Trial of Induction Methods in Premature Rupture of Membranes
This study evaluates the addition of transcervical Foley catheter balloon and vaginal prostaglandin E2 induction in premature rupture of membranes.
- Trial name
- NCT03744078
- Testing
- Foley balloon catheter
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Reflexology, Labor Induction
The Effect of Reflexology on Time to Delivery During Induction of Labor
This prospective, randomized controlled trial evaluates the effect of reflexology on maternal anxiety, labor duration, and pain in women undergoing labor induction with an extra-amniotic balloon (EAB).
- Conditions
- Reflexology, Labor Induction, Extra Amniotic Balloon
- Trial name
- NCT07168187
- Testing
- Reflexology
- Where
- Israel
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Labor Induction, Third Trimester
Uterocervical Angle in Induction of Labor
To evaluate the performance of uterocervical angle (UCA) in the prediction of labor induction.
- Trial name
- NCT03308656
- Testing
- uterocervical angle
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Obesity, Induced; Birth
Effect of Maternal Obesity on Labour Induction in Postdate Pregnancy
This study investigate the progression of labour in 144 normal weight pregnant women (BMI <30) and 144 obese pregnant women (BMI >30) , not in labor admitted for induction of labor.
- Trial name
- NCT02788305
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Pre-eclampsia, Pre-Term
Study of Pregnancy Pathologies Associated With Placental Abnormalities
Pregnancy pathologies can occur from implantation until childbirth. The investigators are interested in the development mechanisms of these pathologies and aim to develop therapies to treat them.
- Conditions
- Pre-eclampsia, Pre-Term, Fetal Growth Retardation
- Trial name
- NCT05188066
- Testing
- Histology
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Premature Birth, Cervical Ripening
Randomized Trial Comparing Misoprostol and Foley Bulb for Labor Induction in the Preterm Gestation
The purpose of this study is to compare the time to delivery of two different cervical ripening methods on the preterm gestation.
- Trial name
- NCT00325026
- Testing
- Misoprostol, Foley bulb
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Florida
Pregnancy, Obesity
When to INDuce for OverWeight? (WINDOW)
The rate of overweight and obese women becoming pregnant is increasing. Obesity in pregnancy along with delivery by cesarean section in obese women is associated with several complications as compared to normal weight women.
- Conditions
- Pregnancy, Obesity, Parturition
- Trial name
- WINDOW (NCT04603859)
- Testing
- Elective induction of labor at 39 gestational weeks and 0 to 3 days
- Where
- 12 sites in Denmark
- Volunteers
- 1,901 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Unfavorable Cervix, Cervical Ripening
Combined Foley Catheter Balloon and PGE2 Vaginal Ovule for Induction of Labor at Term: A Randomized Study
This study evaluates the addition of transcervical Foley catheter balloon and vaginal prostaglandin E2 in induction of labor at term.
- Trial name
- NCT02861079
- Testing
- Foley catheter, PGE2
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Failed Induction of Labor
A Novel Protocol for Labour Induction
The use of foley catheter was tested many times and proved to be effective for induction of labour.
- Trial name
- NCT01506388
- Testing
- foley catheter, Misoprostol, Vaginal IMN
- Where
- 2 sites in Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cairo University