Clinical trials: Infant Conditions
Pregnancy, Postpartum Depression
Rosie the Chatbot: Leveraging Automated and Personalized Health Information Communication
Rosie the Chatbot is an educational chatbot that moms can have on their computers or cellphones and will work by moms typing in their questions about pregnancy, health, infant milestones, and other variety of health related…
- Conditions
- Pregnancy, Postpartum Depression, Infant Development, Infant Conditions
- Trial name
- NCT06053515
- Testing
- Rosie the Chatbot
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Respiratory Distress Syndrome, Transient Tachypnea of Newborn
The Predictive Value of Amniotic Fluid pH and Electrolytes on Neonatal Respiratory Disorders
Amniotic fluid (AF) is a complex structure with a changing content by gestational time. AF pH can be affected by both maternal and fetal conditions such as preterm ruptures of membranes, prematurity and fetal distress.
- Trial name
- NCT02813954
- Testing
- Blood Gas Sampling
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Child Nutrition, Stunting
Impact Evaluation of a Social Franchise Model for Improving Infant and Young Child Feeding and Child Nutrition in Vietnam
Alive \& Thrive is an initiative that aims to improve infant and young child feeding practices and reduce childhood stunting. In Vietnam, Alive \& Thrive's primary intervention is implemented through a social franchise linked…
- Conditions
- Child Nutrition, Stunting, Exclusive Breastfeeding, Complementary Feeding
- Trial name
- NCT01676623
- Testing
- Standard government health services, Alive & Thrive IYCF franchise services, Mass media campaign
- Where
- Vietnam
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- International Food Policy Research Institute
Mesothelioma, Lung Neoplasms
Chest Wall Motion Analysis in Disease
Breathing movements, called chest wall motion, are very complex. The investigators are studying how movement of the abdomen, ribs and diaphragm contribute to breathing and how this differs with different diseases in the chest.
- Conditions
- Mesothelioma, Lung Neoplasms, Surgery, Cystic Fibrosis
- Trial name
- CWM (NCT02958683)
- Testing
- Chest wall motion analysis
- Where
- United Kingdom
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Heart of England NHS Trust
Body Weight
Growth and Tolerance of Cow Milk-Based Infant Formulas
This clinical trial will assess growth, tolerance and adverse events of cow milk-based infant formulas in healthy, term infants.
- Trial name
- NCT01122654
- Where
- 24 sites in United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Mead Johnson Nutrition
Neonatal Hyperbilirubinemia, Phototherapy Complication
Conventional Versus LED Phototherapy and Their Effect on Lymphocytes Subsets of Full Term Neonates With Hyperbilirubinemia
The aim of this study is to investigate the influence of the use of different types of phototherapy on different lymphocytes subsets CD4 and CD8 in the treatment of hyperbilirubinemia in neonates.
- Trial name
- NCT04373980
- Testing
- phototherapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rania Ali El-Farrash
Pulmonary Disease, Chronic Obstructive
Osteoprotegerin (OPG) in Induced Chronic Obstructive Pulmonary Disease (COPD) Sputum
Evaluation of OPG level as disease markers has also been reported. It has been showed that patients with coronary artery disease had higher serum OPG levels than healthy volunteers.
- Trial name
- NCT00655954
- Testing
- Induced sputum
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Pregnancy, Overweight
Preventing Obesity in Military Communities: Mother-Baby
Women with pre-pregnancy obesity, women who exceed recommended weight gain during pregnancy, and children who experience rapid and excess growth during the first year of life are all at risk for subsequent obesity.
- Conditions
- Pregnancy, Overweight, Obesity
- Trial name
- NCT03249324
- Testing
- Positive-Gain Counseling (PGC), Usual Care
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Diarrhoea
A Study on the Safety and Immune Responses to the GVGH altSonflex1-2-3 Vaccine Against Shigellosis in Adults, Children, and Infants
The aim of the current clinical study was to evaluate, for the first time in humans (FTIH), the safety and immunogenicity of the altSonflex1-2-3 candidate vaccine against S. sonnei and S. flexneri serotypes 1b, 2a, and 3a.
- Trial name
- NCT05073003
- Testing
- AltSonflex1-2-3 High Dose, AltSonflex1-2-3 Medium Dose, AltSonflex1-2-3 Low Dose
- Where
- 2 sites in Belgium, Kenya
- Volunteers
- 551 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Intrauterine Growth Restriction
Prediction of Low Birth Weight Infants Using Ultrasound Measurement of Placental Diameter and Thickness
Prediction of Low Birth Weight Infants using Ultrasound Measurement of Placental Diameter and Thickness
- Trial name
- NCT01501851
- Where
- Egypt
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Large for Gestational Age Baby, Macrosomia, Fetal
A First Trimester Prediction Model for Large for Gestational Age Infants: a Preliminary Study
Large for gestational age infants (LGA) have increased risks of adverse short-term perinatal outcomes. This study aims to develop a multivariable prediction model for the risk of giving birth to a LGA baby, by using biochemical…
- Trial name
- PreMoLGA (NCT04838431)
- Testing
- Blood sample and ultrasound at first trimester
- Where
- Italy
- Volunteers
- 503 people, healthy volunteers welcome
- Sponsor
- University of Modena and Reggio Emilia
Development, Infant, Development, Language
Early Neurophysiological Markers of Language Impairments
The present project aims at identifying very early electrophysiological risk markers for language impairments. The long-term goals of the study include the characterization of learning developmental trajectories in children at…
- Conditions
- Development, Infant, Development, Language, Developmental Language Disorder, Learning Disabilities
- Trial name
- NCT05767242
- Testing
- Electrophysiological recording, Behavioral assessment
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Neonatal Sepsis
Salivary C- Reactive Protein, Mean Platelet Volume and Neutrophil Lymphocyte Ratio as Diagnostic Markers for Neonatal Sepsis
To evaluate reliability of salivary C-reactive protein ,mean platelet volume , neutrophil -lymphocyte ratio , and platelet lymphocyte ratio in diagnosis of neonatal sepsis
- Trial name
- NCT04800445
- Testing
- Salivary CRP
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Anesthesia, Anesthesia, Local
Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children
Circumcision is one of the most commonly performed operations in the pediatric population and is a painful procedure. Circumcision is performed with two popular techniques, Plastibell and conventional dissection method (CDM).
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia, Pediatric ALL
- Trial name
- NCT05233683
- Testing
- Caudal block, Dorsal penile nerve block plus ring block, Circumcision with Plastibell
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Saud University
Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered
Preventing Childhood Obesity: A Two-pronged Approach Starting in Pregnancy and the First Year Postpartum
Our longitudinal aim is to reduce childhood obesity using our two-pronged intervention program, which includes healthy food choices and increased physical activity initiated during pregnancy and re-instated in the early period…
- Conditions
- Childhood Obesity, Excessive Weight Gain in Pregnancy With Baby Delivered, Dietary Modification, Healthy Lifestyle Habits
- Trial name
- NCT01129505
- Testing
- Nutrition & Exercise Lifestyle Intervention Program (NELIP)
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Iron Deficiency Anemia of Pregnancy
Adiposity and Iron Requirements in Pregnancy
This study aims to explore how body fat influences the response to either 25 or 50 mg of daily iron supplements during pregnancy.
- Trial name
- ADIPREG (NCT06425796)
- Testing
- Adiposity and Iron Requirements in Pregnancy (ADIPREG)
- Where
- 3 sites in United Kingdom
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Neonatal SEPSIS
Microfluidic Assessment of Clinical Outcomes in Preterm Newborns
Sepsis has its greatest impact in the prematurely born (preterm) population. Neonatal sepsis (sepsis within the first month of life) causes over one million deaths worldwide annually, and is one of the most common, difficult and…
- Trial name
- NCT03291496
- Testing
- Blood Collection Preterm, Blood Collection Term, Adult Blood collection
- Where
- United States
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- University of Florida
Functional Gastrointestinal Disorders (FGIDs), Weight Loss
Effects of Multi-strain Bacillus Spore Probiotics on Growth, Digestive Function, and Gut Microbiota in Cesarean-Delivered Neonates
Infants born by cesarean section commonly show early weight loss and slower recovery of birth weight, together with characteristic patterns of gut microbiota dysbiosis marked by reduced Bifidobacterium and Bacteroides and…
- Trial name
- NCT07320287
- Testing
- RO water, LiveSpo PREG-MOM, LiveSpo CONSY
- Where
- Vietnam
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Anabio R&D
Postpartum Anxiety, Breastfeeding
Postpartum Anxiety, Breastfeeding and Infant Health Among Taiwanese Women
This is a prospective, longitudinal and observational study designed to investigate the trajectories of postpartum anxiety and its determinants in the first year after childbirth.
- Conditions
- Postpartum Anxiety, Breastfeeding, Infant Conditions
- Trial name
- NCT04608721
- Testing
- Postpartum Anxiety
- Where
- Taiwan
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Ministry of Science and Technology, Taiwan
Cystic Fibrosis
Treatment of Metabolic Alkalosis in Acute Exacerbations of Cystic Fibrosis
Adult cystic fibrosis (CF) patients admitted with an acute infection complicated by acid-base disturbance and decreased ventilation will be studied.
- Trial name
- NCT00163852
- Testing
- Normal saline IV, salt tablets
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bayside Health