Clinical trials: Infarction, Myocardial
Myocardial Infarction, Percutaneous Coronary Intervention
Adjunctive, Low-dose tPA in Primary PCI for STEMI
STRIVE will evaluate the use of adjunctive, low-dose intracoronary tissue plasminogen activator during primary percutaneous coronary intervention (PCI) for patients with ST elevation myocardial infarction (STEMI) in reducing the…
- Trial name
- STRIVE (NCT03335839)
- Testing
- tissue plasminogen activator, Saline
- Where
- 3 sites in Canada
- Volunteers
- 210 people
- Sponsor
- Population Health Research Institute
Coronary Disease, Cardiovascular Diseases
Dietary Fatty Acids, PPAR Activated Genes, and CHD
To examine the relationship between genetic and dietary factors that modify the risk of coronary heart disease (CHD).
- Conditions
- Coronary Disease, Cardiovascular Diseases, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00071019
- Volunteers
- 4,547 people
- Sponsor
- Harvard School of Public Health (HSPH)
Acute ST-segment Elevation Myocardial Infarction
Effects of Glucagon Like Peptide-1 on No-reflow
The investigators planned to evaluate the effects of liraglutide on no-reflow in patients with acute ST-segment elevation myocardial infarction (STEMI).
- Trial name
- NCT02507128
- Testing
- liraglutide
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Chen Wei Ren, MD
Acute Myocardial Infarction
Randomized, Controlled Study on Short-term Psychotherapy After Acute Myocardial Infarction
Psychosocial factors play an important role in the pathophysiology of acute myocardial infarction (AMI), but it is not known if psychotherapy is beneficial after the contemporary treatment of AMI consisting of medical and…
- Trial name
- STEP-IN-AMI (NCT00769366)
- Testing
- Psychotherapy, Medical therapy
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- San Filippo Neri General Hospital
Mitral Regurgitation
STrategies for Antithrombotic tReatment Following Transcatheter Edge-to-Edge Repair in Patients With an Indication for Oral Anticoagulant
Mitral regurgitation (MR) is the most common valvular heart disease, affecting approximately 24.2 million people worldwide (with a higher prevalence in older age groups).
- Trial name
- STAR-TEER Ⅰ (NCT06901466)
- Testing
- Experimental: Rivaroxaban monotherapy, Active Comparator: Rivaroxaban+Clopidogrel
- Where
- China
- Volunteers
- 880 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Acute Coronary Syndrome, Myocardial Infarction
Magnetocardiography Using a Novel Analysis System (Cardioflux) in the Evaluation of Emergency Department Observation Unit Chest Pain Patients
Genetesis is a cardiac diagnostics company which presents a novel magnetocardiogram (MCG) analysis system called CardioFlux. This investigation presents a new, noninvasive diagnostic option to use MCG for rapid diagnosis of acute…
- Trial name
- NCT03255772
- Testing
- Magnetocardiography
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Genetesis Inc.
End Stage Renal Disease, Cardio-Renal Syndrome
Cardio-Renal Registry
Cardiovascular disease is the leading cause of morbidity and mortality among patients with chronic kidney disease (CKD). Even after adjustment for known cardiovascular risk factors, including diabetes and hypertension, mortality…
- Conditions
- End Stage Renal Disease, Cardio-Renal Syndrome, Myocardial Infarction, Cerebrovascular Accident
- Trial name
- BHCRR (NCT06521801)
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 60,000 people
- Sponsor
- Queen Mary University of London
Coronary Arteriosclerosis, Myocardial Infarction
Culturally-Tailored Approach to Improve Medication Use in Patients With Heart Attacks
Our research aims to improve the use of medicines known to prevent recurrent heart attacks. In particular, we know that statin treatment is useful after heart attacks, but many patients do not use it.
- Trial name
- NCT00426231
- Testing
- Navigation by a health worker, Information control
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Johns Hopkins University
Myocardial Infarction
Short-Term Application of Tocilizumab Following Myocardial Infarction
Introduction: Interleukin 6 (IL-6) is a cytokine that has a pro-inflammatory effect on the immune system. In acute MI IL-6 levels rapidly increase in response to ischemia and inflammation.
- Trial name
- STAT-MI (NCT02419937)
- Testing
- Tocilizumab
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Keesler Air Force Base Medical Center
Heart; Dysfunction Postoperative, Cardiac Surgery, Genetic Predisposition to Disease
Identification of Genomic Predictors of Adverse Events After Cardiac Surgery
This study aims to identify genetic causes of adverse events after cardiac surgery, such as atrial fibrillation, myocardial infarction, renal dysfunction and heart failure.
- Conditions
- Heart; Dysfunction Postoperative, Cardiac Surgery, Genetic Predisposition to Disease, Atrial Fibrillation, Myocardial Infarction
- Trial name
- CABGGenomics (NCT01258231)
- Where
- 3 sites in United States
- Volunteers
- 4,000 people
- Sponsor
- Brigham and Women's Hospital
Myocardial Reperfusion Injury
Post Cond No Reflow
After having shown that postconditioning allowed a significant 36% reduction of infarct size as assessed by blood levels of myocardial enzymes in acute myocardial patients, the investigators objective is to assess the effect of…
- Trial name
- NCT01208727
- Testing
- postconditioning
- Where
- France
- Volunteers
- 44 people
- Sponsor
- Hospices Civils de Lyon
Prevalence of Myocarditis in MINOCA Patients
Prevalence of Myocarditis in Patients Suspected Myocardial Infarction With Non-Obstructive Coronary Arteries
This study aims to determine the prevalence of myocarditis among patients suspected of having myocardial infarction with non-obstructive coronary arteries (MINOCA) and to analyze its clinical characteristics, diagnostic markers .
- Trial name
- NCT06966531
- Testing
- Coronary angiography
- Volunteers
- 148 people
- Sponsor
- Assiut University
ST Elevation Myocardial Infarction, Myocardial Infarction
Dapagliflozin in STEMI
The goal of this clinical trial is to assess the safety and efficacy of SGLT2i in limiting infarct size in patients with STEMI referred for PPCI.
- Trial name
- DAPA STEMI (NCT06174753)
- Testing
- Dapagliflozin 10mg Tab, CMR
- Where
- Canada
- Volunteers
- 256 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Acute Myocardial Infarction
A Medical Research Study to Evaluate the Effects of ACT-246475 in Adults With Heart Attack
The goal of this study is to find out how fast a drug called selatogrel (ACT-246475) can prevent platelets from binding together. This study will also help to find out more about the safety of this new drug.
- Trial name
- NCT03487445
- Testing
- Selatogrel 8 mg, Selatogrel 16 mg
- Where
- 6 sites in Belgium, Israel and 1 more
- Volunteers
- 48 people
- Sponsor
- Viatris Innovation GmbH
ST-elevation Myocardial Infarction, Acute Myocardial Infarction
Should Integrilin be an Integral Part of Adjunctive Therapy in Patients Undergoing Primary PCI for ST-Elevation MI?
The aim of this observational study is to evaluate the in hospital and 6 month outcomes of the use of Glycoprotein IIb/IIIa inhibitor eptifibatide as adjunctive therapy in patients undergoing primary Percutaneous Coronary…
- Trial name
- NCT01991366
- Where
- United States
- Sponsor
- Medstar Health Research Institute
Coronary Heart Disease, Stroke
The Copenhagen City Heart Study
The Copenhagen City Heart Study is an ongoing cardiovascular population study initiated in 1976 which has examined approximately 25,000 individuals from the general population.
- Conditions
- Coronary Heart Disease, Stroke, Heart Failure, Cancer
- Trial name
- CCHS (NCT02993172)
- Volunteers
- 23,891 people
- Sponsor
- Bispebjerg Hospital
ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI
Ticagrelor Administered as Standard Tablet or Orodispersible Formulation
Randomized clinical study evaluating superiority in platelet inhibition after administration of Ticagrelor 180 mg loading dose as an orodispersible formulation versus traditional coated tablets in patients admitted for ST…
- Trial name
- TASTER (NCT03822377)
- Testing
- Ticagrelor orodispersible tablets, Ticagrelor standard tablets
- Where
- Italy
- Volunteers
- 130 people
- Sponsor
- Azienda Ospedaliero Universitaria di Sassari
Thrombocytopenia, Myocardial Infarction
Aspirin in Patients With Myocardial Infarction and Thrombocytopenia
Primary Objective: To determine the risk of bleeding from ASA therapy in thrombocytopenic patients who develop Acute Coronary Syndrome (ACS), and assess its effect on the overall morbidity and mortality in these patients as well…
- Trial name
- NCT00501345
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- M.D. Anderson Cancer Center
Myocardial Infarction Postoperative, Myocardial Injury
Preoperative BNP: Epidemiological Patterns, Management Strategies and Cost Analysis of Care
Recently, the use of preoperative BNP as a preoperative risk stratifcation tool was added to the Canadian Cardiovascular Society (CCS) guidelines (4) on perioperative cardiac risk assessment and management for patients who…
- Conditions
- Myocardial Infarction Postoperative, Myocardial Injury, Death, Cardiac
- Trial name
- NCT04077294
- Testing
- Cardiac risk stratification using preoperative BNP measurement, followed by postoperative cardiac monitoring, Use of traditional perioperative cardiac risk stratification only
- Where
- Canada
- Volunteers
- 333 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Myocardial Infarction
Autologous Bone Marrow Derived Stem Cells for Acute Myocardial Infarction
One of the important reasons for human dying is Ischemic heart disease (IHD). The most reason is coronary artery disease. Beside morbidity, IHD induce myocardial infarction and necrosis which due to congestive heart failure.
- Trial name
- NCT01167751
- Testing
- MNC, AC 133, Control
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Royan Institute