Clinical trials: Infection Hip
Bone Infection, Osteomyelitis
Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections
Because of its prolonged terminal half-life, dalbavancin is an extremely attractive option in treating Gram-positive infections caused by S. aureus including MRSA, and streptococcal species.
- Conditions
- Bone Infection, Osteomyelitis, Septic Arthritis, Joint Infection
- Trial name
- NCT03426761
- Testing
- Dalbavancin, Vancomycin
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Infectious Diseases Physicians, Inc.
Infection, Debridement With Prosthesis Retention
Treatment Results on Patients With Debridement and Prosthesis Retention in the Hip
This study presents the investigators results on patients treated for infection in the implemented hip prosthesis. Debridement and prosthesis retention is the method, followed by antibiotic treatment.
- Trial name
- NCT00757445
- Where
- Norway
- Volunteers
- 105 people
- Sponsor
- Sorlandet Hospital HF
Total Joint Arthroplasty, Periprosthetic Joint Infections
Genetic Susceptibility to Periprosthetic Joint Infections
The investigators primary objective is to identify genetic factors that may increase the risk of patients developing a periprosthetic joint infections (PJI) following total joint arthroplasty (TJA).
- Trial name
- NCT05159739
- Testing
- Blood Draw or Saliva/Cheek Cell Sample:
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Utah
Prosthesis Related Infections
Biodistribution and Dosimetry Evaluation of [124I]FIAU
This protocol will evaluate the biodistribution and dosimetry of [124I]FIAU in both healthy volunteers and patients with prosthetic joint infections.
- Trial name
- NCT01337466
- Testing
- [124I]FIAU
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- BioMed Valley Discoveries, Inc
Total Hip Replacement
Evaluation of Conventional Antibiotic Prophylaxis During a Change of Hip or Knee Infected at a Time
Infection is a serious complications after undergoing total hip replacement. It occurs in about 1% of cases. The optimal treatment of these infections is discussed.
- Trial name
- NCT02272205
- Testing
- Retrospective analysis of records
- Volunteers
- 80 people
- Sponsor
- University Hospital, Strasbourg, France
Infection
Intra-articular Vancomycin Powder in Knee and Hip Arthroplasty
The purpose of this study is to compare infection rates when patients, elected for primary or aseptic revision THA / TKA, have a single intravenous antibiotic dose versus one single intravenous antibiotic dose in combination with…
- Trial name
- NCT04399642
- Testing
- Arthroplasty
- Where
- Canada
- Volunteers
- 1,832 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Implant Infection, Skeletal Sarcoma
Implant-Related Infections in Patients With Skeletal Sarcomas
The aim of this observational study is to gain knowledge on the microbial and immunological factors behind implant-related infections in patients with skeletal sarcoma.
- Conditions
- Implant Infection, Skeletal Sarcoma, Hip Arthritis, Prosthesis-Related Infections
- Trial name
- IRISSAR (NCT07264296)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Urinary Tract Infections
A Trial of Different Methods for Bladder Drainage in Hip Surgery Patients
The aim of the project is to evaluate differences between intermittent and indwelling catheterisation in patients with hip surgery.
- Trial name
- NCT01333254
- Testing
- Intermittent urinary catheterisation
- Where
- Sweden
- Volunteers
- 170 people
- Sponsor
- Region Örebro County
Surgical Site Infection
One Stage Versus Two Stage For Periprosthetic Hip And Knee Infection
The purpose of this study is to compare the outcomes of two different treatment options commonly used to manage periprosthetic joint infection (PJI), an infection around the artificial knee or hip.
- Trial name
- NCT02734134
- Testing
- One-stage exchange joint replacement surgery, Two-stage exchange joint replacement surgery
- Where
- 5 sites in United States
- Volunteers
- 343 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Prosthetic Joint Infection, Debridement With Prosthesis Retention
Antibiotic-coated Braided Suture Study
The purpose of this study is to evaluate whether the use of antibiotic-coated (triclosan) braided sutures is non-inferior or potentially superior to standard monofilament sutures in patients with prosthetic joint infections…
- Conditions
- Prosthetic Joint Infection, Debridement With Prosthesis Retention, Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee
- Trial name
- NCT07322289
- Testing
- VICRYL™ Plus (Coated VICRYL™ Plus Antibacterial), Polydioxanone (PDS™ II ) Sterile Synthetic Absorbable Surgical Suture-Monofilament
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Miami
Bone Diseases, Infectious
Drug Penetration Into Bone After Repeated Oral Administration of Debio 1450 to Patients Undergoing Hip Replacement Surgery
Debio 1450 is being developed for the treatment of staph (staphylococcal) infections. How fast and completely an antibiotic penetrates into bone is used to determine how effective it might be to treat infections related to bones…
- Trial name
- NCT02726438
- Testing
- Debio 1450
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Debiopharm International SA
Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee
Safety and Efficacy of CEM-102 With Rifampin Compared to Standard Therapy in Patients With Prosthetic Joint Infections or Spacer Infection
To determine if oral antibiotic treatment with CEM-102 and Rifampin is as effective and safe as the standard of care antibiotic therapy for the treatment of hip and knee prosthetic joint or spacer infections
- Conditions
- Prosthetic Joint Infections of Hip, Prosthetic Joint Infections of Knee, Infected Spacers
- Trial name
- NCT01756924
- Testing
- CEM-102, IV or Oral standard of care antibiotics, Rifampin
- Where
- 13 sites in United States
- Volunteers
- 14 people
- Sponsor
- Arrevus Inc.
Infection, Drainage
Comparison of Negative Pressure Wound Therapy vs. Conventional Dressings for Prevention of Wound Complications After Revision THA
Wound complications and surgical site infections following revision total joint arthroplasty result in significant morbidity and cost.
- Trial name
- NCT03321799
- Testing
- Negative Pressure Wound Therapy (NPWT), Sterile Antimicrobial Dressings
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Osteoarthritis, Infection
Prospective, Randomized Study Evaluating The Efficacy of Chlorhexidine Gluconate Impregnated No-Rinse Cloths.
Subjects in the study were randomized to a treatment group using Chlorhexidine cloths or a standard-of-care group who only had a bath with antibacterial soap and water.
- Trial name
- SAGE (NCT02469311)
- Testing
- chlorhexidine impregnated cloths, Standard of care bathing with antibacterial soap and water
- Volunteers
- 539 people
- Sponsor
- LifeBridge Health
Hip Arthroplasty Replacement
Follow up Study of Patients Undergoing Total Hip Arthroplasty CERAFIT® Grafted With Poly Sodium Styrene Sulfonate
The risk of infection after primary Total Hip Arthroplasties (THA)is generally estimated to be less than 1% but remains a severe and costly complication, source of morbidity and even mortality.
- Trial name
- NCT01454271
- Testing
- Total Hip Arthroplasty Replacement
- Where
- France
- Sponsor
- Societe ACTIVBIOMAT
Hip Effusion, Septic Arthritis
Accuracy of Pediatric Emergency Medicine Providers in Diagnosing Hip Effusions Using Point of Care Ultrasound
The purpose of this study is to determine if pediatric emergency medicine providers can accurately diagnose a hip effusion using point-of-care ultrasound (POCUS) compared to radiology ultrasound (RADUS).
- Conditions
- Hip Effusion, Septic Arthritis, Transient Synovitis, Hip
- Trial name
- NCT05971745
- Where
- 6 sites in United States, Australia
- Volunteers
- 161 people
- Sponsor
- Connecticut Children's Medical Center
Femoral Neck Fracture, Infection
Early Periprosthetic Joint Infection and Outcome Debridement, Antibiotics and Implant Retention
Introduction Periprosthetic joint infection (PJI) is a severe complication to hip arthroplasty for femoral neck fractures (FNF).
- Trial name
- DAIR (NCT02771639)
- Testing
- Hip arthroplasty
- Volunteers
- 736 people
- Sponsor
- Sundsvall Hospital
Bone Loss, Hip Prosthesis Infection
Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN)
In this prospective multicenter study, a population of adult individuals consecutively treated for revision hips, requiring a custom-made acetabular implant for non-oncological reasons, will be included.
- Conditions
- Bone Loss, Hip Prosthesis Infection, Arthroplasty Complications
- Trial name
- CustomPN (NCT06527664)
- Testing
- custom-made acetabular implant
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Istituto Ortopedico Rizzoli
Wound Healing Time, Total Hip Arthroplasty (THA)
Wound Healing, Dressing Type, and Dressing Change Frequency in THA
Surgical wound complications following primary total hip arthroplasty remain a significant clinical challenge despite advances in wound care technologies.
- Trial name
- CAP-HIP (NCT07655388)
- Testing
- VACUTEX™ wound dressing, Octenisept® wound care dressing
- Where
- Serbia
- Volunteers
- 90 people
- Sponsor
- Clinical Center of Vojvodina
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai