Clinical trials: Infection Post Op
Body Temperature, Postoperative Infection
Steadysense -Early Detection of Postoperative Infections Through Continuous Temperature Measurement
The goal of this observational study is to review whether postoperative infections can be detected earlier by a continuous measurement of body temperature of patients compared to single daily measurements.
- Conditions
- Body Temperature, Postoperative Infection, Pneumonia
- Trial name
- NCT06044428
- Testing
- Steadytemp®
- Where
- Austria
- Volunteers
- 103 people
- Sponsor
- Medical University of Graz
Pneumonia, Cardiac Surgery
Catheter Outcomes With Sternotomy Cardiac Operated
Pneumonia occurs frequently in patients undergoing cardiac surgery and allows to increase their mortality. While chest physical therapy plays a crucial role to prevent postoperative pneumoniae, painful mobilization of the sternum…
- Conditions
- Pneumonia, Cardiac Surgery, Multiperforated Catheter, Analgesia
- Trial name
- STERNOCAT (NCT01648777)
- Testing
- L bupivacaine
- Where
- France
- Volunteers
- 1,502 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Impacted Tooth, Postoperative Complications in Maxillofacial Surgery
Effectiveness of Postoperative Topical and Oral Antibiotics on Impacted Mandibular 3rd Molar Surgery.
This randomized controlled trial evaluates the effectiveness of postoperative topical antibiotics compared with oral antibiotics in patients undergoing surgical extraction of impacted mandibular third molars.
- Conditions
- Impacted Tooth, Postoperative Complications in Maxillofacial Surgery, Surgical Wound Infection, Facial Pain
- Trial name
- POTA-M3S (NCT07573033)
- Testing
- Topical Antibiotic, Oral antibiotic therapy
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Liaquat College of Medicine and Dentistry
Bacterial Infection, Postoperative Infection
Neutrophil CD64 and Procalcitonin as Novel Biomarkers for Postoperative Infections
Postoperative complications, especially bacterial infections, are relatively common and cause increased morbidity and mortality.
- Conditions
- Bacterial Infection, Postoperative Infection, Abdominal Infection
- Trial name
- NCT01250574
- Testing
- CD64 and Procalcitonin
- Where
- Norway
- Volunteers
- 173 people
- Sponsor
- University Hospital, Akershus
Surgical Site Infection, Post-Op Infection
Analysis of Risk Factors for Surgical Site Infections in Patients With Acute Abdomen at Hospital of State University of Haiti
The purpose of this study is to identify the risk factors associated with surgical site infection.
- Trial name
- NCT06480344
- Where
- Haiti
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Haiti
Colon Cancer, Rectal Cancer
Comparison of Two Bundles of Care to Reduce Surgical Site Infection in Colorectal Surgery (CCR-VINCat 2)
There is controversy about the maximum number of elements to be included in a surgical site infection (SSI) prevention bundle and the possibility of its implementation at a multi-center level.
- Conditions
- Colon Cancer, Rectal Cancer, Surgical Site Infection
- Trial name
- CCR-VINCat2 (NCT06244836)
- Testing
- Implementation of a bundle of care
- Where
- Spain
- Volunteers
- 32,205 people
- Sponsor
- Hospital de Granollers
Tonsillectomy, Infections
Head-Only Draping in Pediatric Tonsillectomy
This single-center, interventional study will compare 30-day postoperative infection rates in pediatric tonsillectomy performed with either head-only draping or traditional full-body draping.
- Trial name
- NCT07347301
- Testing
- Full-Body Surgical Draping, Head-Only Surgical Draping
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- NYU Langone Health
Wearable Devices
Wearable Devices for Early Detection of Postoperative Infection
This systematic review aims to evaluate the efficacy, accuracy, and clinical applicability of wearable infection detection wristbands in postoperative patients across ophthalmology, orthopaedic surgery, and general surgery.
- Trial name
- Wearable Wrist (NCT07334925)
- Testing
- White Blood Cell (WBC), C-reactive Protein (CRP)
- Where
- Egypt
- Volunteers
- 1,284 people
- Sponsor
- Benha University
Surgical Site Infections, Post Operative Complication
2% Chlorhexidine Gluconate Skin Cloths to Prevent SSI in Spine Surgery Patients
Surgical site infection (SSI) following spinal surgery is a frequent complication and results in higher morbidity, mortality and healthcare costs.
- Trial name
- DeSSI (NCT02490631)
- Testing
- 2% chlorhexidine gluconate cloths
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Vanderbilt University
Hyperglycemia, Craniotomy
Impact of Severe Intraoperative Hyperglycemia on Infection Rate After Elective Intracranial Interventions
Severe intraoperative hyperglycemia (SIH) is recognized as one of the important risk factors for the increasing of the postoperative infections rate, which can negatively affect the final outcome of surgical treatment.
- Conditions
- Hyperglycemia, Craniotomy, Infection Post Op
- Trial name
- NCT04285359
- Testing
- Intracranial Interventions
- Where
- 2 sites in Italy, Russia
- Volunteers
- 514 people
- Sponsor
- Burdenko Neurosurgery Institute
Postoperative Infection, Geriatrics
Postoperative Infectious Complications Calculator for Elderly Patients
The investigators established a first-ever convenient scoring system for clinicians to assess the risk of Postoperative infectious complications (PICs) for elderly patients.
- Conditions
- Postoperative Infection, Geriatrics, Prediction
- Trial name
- NCT06265493
- Where
- China
- Volunteers
- 37,230 people
- Sponsor
- Weidong Mi
Sepsis, Septic Shock
The Role of Emergency Neutrophils and Glycans in Postoperative and Septic Patients
Surgical trauma elicits an immune response aiming to initiate healing and remove debris and damaged tissue locally at the wound site (1).
- Conditions
- Sepsis, Septic Shock, Sepsis, Severe, Post-Op Complication
- Trial name
- NCT04117568
- Testing
- Blood sampling
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Göteborg University
Open Fracture, Post-Op Wound Infection
Noninferiority Comparison of Prophylactic Open Fracture Antimicrobial Regimens
To demonstrate noninferiority of three different empiric antimicrobial regimens compared to the traditional antimicrobial regimen for the management of grade III open fractures as well as evaluate outcomes among these groups.
- Trial name
- NCT03560232
- Testing
- Ceftriaxone, Ampicillin/sulbactam, Piperacillin/tazobactam
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Mercy Health Ohio
Tonsillitis
Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea
The purpose of this study is to determine if auricular acupuncture significantly reduces post-operative pain in comparison to the standard of care.
- Trial name
- BFA (NCT02571075)
- Testing
- Auricular acupuncture
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
Lobectomy is a major, high-risk surgical procedure that in addition to one-lung ventilation (OLV) exerts a potent surgical stress response.
- Conditions
- Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute, Postoperative Pain, Chronic, Infections Postoperative
- Trial name
- NCT05172739
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- University of Crete
Wound Infection
Randomized Trial to Assess PO Versus IV Antibiotics
The goal of this study is to evaluate the effect of treatment of post-op wound infection in long bones after fracture fixation or joint fusion and either: (Group 1) operative debridement and PO antibiotic treatment for 6 weeks…
- Trial name
- POvIV (NCT01714596)
- Testing
- PO versus IV antibiotics Route of administration evaluation
- Where
- 24 sites in United States
- Volunteers
- 233 people
- Sponsor
- Major Extremity Trauma Research Consortium
C. Acnes, Phototherapy
Photodynamic Therapy for Cutibacterium Acnes (C. Acnes) Decolonization of the Shoulder Dermis
This is a prospective, randomized controlled trial to evaluation the ability of 5-aminolevulinic acid HCL topical solution photodynamic therapy to decrease the colonization of Cutibacterium acnes (C.
- Conditions
- C. Acnes, Phototherapy, Postoperative Infection, Arthroscopic Rotator Cuff Repair
- Trial name
- NCT04636242
- Testing
- Skin Biopsy, 5 Aminolevulinic Acid + Phototherapy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Hyperoxia, Postoperative Complication
Individualized Perioperative Open-lung Ventilatory Strategy With High Versus Conventional Inspiratory Oxygen Fraction (iPROVE-O2).
The iPROVE-O2 trial aims at comparing the efficacy of high and conventional FiO2 within a perioperative individualized ventilatory strategy to reduce the overall incidence of SSI.
- Conditions
- Hyperoxia, Postoperative Complication, Surgical Site Infection
- Trial name
- iPROVE-O2 (NCT02776046)
- Testing
- High FiO2, Conventional FiO2
- Where
- Spain
- Volunteers
- 756 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Biofilms, Thoracic Surgery
Biofilm on Chest Drains After Thoracic Surgery: Clinical Impact and Antibiotic Resistance
This prospective observational study aims to investigate the frequency and clinical significance of biofilm formation on thoracic chest drains used after thoracic surgery.
- Conditions
- Biofilms, Thoracic Surgery, Postoperative Infection, Antibiotic Resistance, Bacterial
- Trial name
- NCT07228598
- Testing
- Chest Drain Tip Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 165 people
- Sponsor
- Caner İşevi, MD
Post Operative Wound Infection, Graft Uptake
Does Antibiotics Use During Surgery Help to Decrease Wound Infection and Increase Success After Ear Surgery in Children
This study assess whether there is any role of antibiotics to decrease wound infection and increase the success of surgery
- Conditions
- Post Operative Wound Infection, Graft Uptake, Myringoplasty
- Trial name
- NCT03700814
- Testing
- Co-amoxiclav
- Volunteers
- 60 people
- Sponsor
- Tribhuvan University, Nepal