Clinical trials: Infection Prophylaxis
HIV/AIDS
Developing a Patient Navigation Intervention for PrEP Continuum of Care Among Young Latino MSM (PrEParate)
This study aims to help young Latino gay and bisexual men access sexual health information, including PrEP. Participants will be randomly assigned to either the patient navigation or the usual care condition and followed for 6…
- Trial name
- NCT04048382
- Testing
- Patient Navigation, Usual Care
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- San Diego State University
CIED Related Infection
World-wide Randomized Antibiotic Envelope Infection Prevention Trial
Medtronic , Inc. is sponsoring the World-wide Randomized Antibiotic Envelope Infection Prevention Trial (WRAP-IT), a randomized, prospective, multi-center, single blinded, post-market, interventional clinical study.
- Trial name
- WRAP-IT (NCT02277990)
- Testing
- TYRX™ Absorbable Antibacterial Envelope
- Where
- 181 sites in United States, Austria and 23 more
- Volunteers
- 7,075 people, healthy volunteers welcome
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Dental Plaque and Gingivitis
The Comparative Effects of Using 0.12% Chlorhexidine and Silver Nanoparticles Mouthwashes in Medical Students
This double-blind, randomized intervention study aims to evaluate and compare the efficacy of 0.12% Chlorhexidine (CHX) mouthwash and Nano Silver (AgNPs) mouthwash.
- Trial name
- mouthwash (NCT06963788)
- Testing
- Chlorhexidine 0,12%, 0,9% Chloride Sodium, Silver nanoparticles mouthwash
- Where
- Vietnam
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Cesarean Section, Infection
Trial Comparing the Optimal Timing of Antibiotic Prophylaxis at the Time of Cesarean Delivery
The purpose of this study is to evaluate the rates of maternal and neonatal infectious morbidity in gravid patients undergoing cesarean delivery.
- Trial name
- NCT00811603
- Testing
- Cefazolin (Timing of Antibiotic Prophylaxis)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- MemorialCare
Neonatal Infection
Prevention of Bacterial Infections in Newborn
The last decade has witnessed an important reduction of the mortality in children under 5 years but such reduction has not impacted in neonates.
- Trial name
- PregnAnZI (NCT01800942)
- Where
- The Gambia
- Volunteers
- 829 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Surgical Wound Infection
Closed Incision Negative Pressure Wound Therapy for the Prevention of Surgical Site Infections in Abdominal Surgery
Surgical site infections (SSI) are a frequent complication in abdominal surgery. SSI lead to worse outcomes for the affected patients and significantly higher healthcare costs.
- Trial name
- CISSI (NCT06068517)
- Testing
- Closed incision negative pressure wound therapy, Standard dressing
- Where
- Switzerland
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Papillomavirus Infections
Efficacy Against Oral Persistent Infection, Immunogenicity and Safety of the 9-valent Human Papillomavirus Vaccine (9vHPV) in Men Aged 20-45 Years (V503-049)
The purpose of this study is to evaluate the efficacy, immunogenicity and safety of the 9vHPV vaccine in men 20 to 45 years of age.
- Trial name
- NCT04199689
- Testing
- 9vHPV Vaccine
- Where
- 103 sites in United States, Belgium and 14 more
- Volunteers
- 6,033 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Diarrhea, Acute Respiratory Infection
Zinc Sulphate vs. Zinc Amino Acid Chelate
Acute respiratory infection and acute diarrhea are among the most prevalent diseases of childhood increase the burden of morbidity and mortality in children under 5 years.
- Trial name
- ZAZO (NCT01791608)
- Testing
- Zinc sulfate as dietary supplementation, Zinc amino acid chelate as dietary supplementation, Milk without fortification without zinc
- Where
- Colombia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- CES University
COVID-19
Safety and Immunogenicity Study of Inactivated Vaccine for Prophylaxis of SARS CoV-2 Infection (COVID-19)
This study is a randomized, double-blinded, and placebo controlled phase Ⅰ/Ⅱ clinical trial of the SARS-CoV-2 inactivated vaccine manufactured by Sinovac Research \& Development Co., Ltd.
- Trial name
- NCT04352608
- Testing
- Two doses of medium dosage inactivated SARS-CoV-2 vaccine at the emergency vaccination schedule, Two doses of high dosage inactivated SARS-CoV-2 vaccine at the emergency vaccination schedule, Two doses of medium dosage inactivated SARS-CoV-2 vaccine at the routine vaccination schedule
- Where
- China
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- Sinovac Research and Development Co., Ltd.
Hiv, Substance Use Disorders
An Intervention to Improve HIV Pre-exposure Prophylaxis Initiation, Adherence and Linkage to Care for Recently Incarcerated Men Who Inject Drugs.
Pre-exposure prophylaxis (PrEP) is effective in preventing HIV infection among people who inject drugs (PWID) yet studies suggest that its use is low among this population which is particularly vulnerable to HIV infection.
- Trial name
- NCT06316089
- Testing
- PrEPared for Release
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
HIV Infections
HIV Prevention Among At-risk Latinos in the Heartland
This study is a randomized controlled trial that evaluates the efficacy of a network intervention to promote regular HIV testing and prevention (risk reduction and PrEP awareness and referrals) among friendship networks of Latino…
- Trial name
- NCT04563715
- Testing
- HIV counseling and testing, Network intervention
- Where
- 3 sites in United States
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
HIV Infections
Mefloquine Prophylaxis in HIV-1 Individuals: a Randomized Placebo-controlled Trial
This is a randomized placebo controlled trial. Malaria chemoprophylaxis with mefloquine in asymptomatic HIV-infected adults living in a malaria endemic region of Luanshya, Zambia will be compared to a placebo control group and…
- Trial name
- NCT00373048
- Testing
- mefloquine
- Where
- Zambia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Covid19, COVID-19 Prevention
Hydroxychloroquine (HCQ) as Post Exposure Prophylaxis (PEP) for Prevention of COVID-19
COVID-19 affected more than 9 million of people with more than 130 thousand death in India. If adequate preventive and therapeutic measures are not taken, India has very high risk of affecting million of more people with high…
- Trial name
- PEP-CQ (NCT04858633)
- Testing
- Hydroxychloroquine (HCQ), Standard care
- Where
- India
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Varicella Zoster Virus Infection, Herpes Simplex Virus Infection
Bioequivalence Study in Healthy Volunteers of a New Paediatric Formulation of Valacyclovir
A new paediatric formulation (oral liquid) has been developed for flexible and accurate dosing of valacyclovir in children. To establish the bioavailability of this new formulation, healthy volunteers will be exposed to the new…
- Trial name
- VALID-I (NCT01689285)
- Testing
- valacyclovir tablet, valacyclovir oral solution
- Where
- Netherlands
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cholera
Single Dose Azithromycin to Prevent Cholera in Children
This study aims to determine whether single-dose azithromycin is effective in preventing cholera in children who are at extremely high risk of infection.
- Trial name
- NCT04326478
- Testing
- Azithromycin
- Where
- Bangladesh
- Volunteers
- 2,475 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Rabies, Japanese Encephalitis
Safety and Immunogenicity of 2 Different Vaccination Schedules of Rabies and Japanese Encephalitis Vaccines in Healthy Adult Subjects
Establish non-inferiority of the immune response and evaluate the safety and tolerability of Rabies and Japanese Encephalitis (JE) vaccines given concomitantly or alone and according to either of 2 schedules for preexposure…
- Trial name
- NCT01662440
- Testing
- Rabies, Japanese Encephalitis
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 661 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Surgical Site Infection, Brain Tumor
Infection Prevention Bundle in Brain Tumor Surgery
This study aimed to evaluate the effectiveness of an infection prevention bundle on surgical site infections in patients undergone brain tumor surgery.
- Trial name
- NCT04285697
- Testing
- infection prevention bundle
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Skin and Soft Tissue Infections, Hiv
ASAP: Access to Syringes at Pharmacies for the Prevention of Bloodborne Infections Among People Who Inject Drugs
Access to Syringes at Pharmacies (ASAP) is a refinement of an evidence-based, pharmacy intervention to increase pharmacy-based sales of syringes to PWID in order to reduce bloodborne illnesses among them.
- Conditions
- Skin and Soft Tissue Infections, Hiv, Hepatitis C, Bloodstream Infection
- Trial name
- ASAP (NCT05270135)
- Testing
- ASAP
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Arizona
COVID-19
Hydroxychloroquine in the Prevention of COVID-19 Infection in Healthcare Workers
In order to assess the efficacy of hydroxychloroquine treatment weekly for a total of 7 weeks in the prevention of COVID-19 infection, three hundred sixty (360) Healthcare workers with high risk exposure to patients infected with…
- Trial name
- NCT04333225
- Testing
- Hydroxychloroquine
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
HIV Infections
Tenofovir Gel in Pregnancy and Lactation
Tenofovir 1% gel is an investigational vaginal microbicide intended to reduce the risk of transmission of HIV. Pregnant women and mothers who have recently given birth often maintain sexual activity, and research has shown that…
- Trial name
- NCT01136759
- Testing
- Tenofovir 1% gel
- Where
- 2 sites in United States
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.