Clinical trials: Infection Surgical Wound
Surgical Site Infection, Infection; Cesarean Section
Study to Evaluate DACC Dressings for the Prevention of Surgical Site Infections in Women Undergoing Caesarean Section.
Surgical site infections (SSIs) constitute an important medical and socioeconomic problem worldwide. Despite the fact that the risk factors for SSIs were identified and the continuously increasing medical knowledge in the fields…
- Trial name
- NCT02168023
- Testing
- DACC impregnated dressing, Standard surgical dressing
- Where
- Poland
- Volunteers
- 543 people
- Sponsor
- Medical University of Warsaw
Laparotomy
Supplemental Oxygen and Complications After Abdominal Surgery (The PROXI-trial)
Aim: To investigate the effect of high intra- and postoperative oxygen concentration (80%, as opposed to normally 30%) on surgical wound infection and pulmonary complications after abdominal surgery.
- Trial name
- NCT00364741
- Testing
- Oxygen
- Where
- 14 sites in Denmark
- Volunteers
- 1,400 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Spinal Fusion, Spinal Stenosis
Vancomycin Powder Combined With Autogenous Bone Graft as a Prevention for Post-operative Infection for Spine Surgery
Deep surgical site infection (DSSI) is one of the most challenging complications for spinal surgeons and can lead to a poor clinical outcome.
- Conditions
- Spinal Fusion, Spinal Stenosis, Spondylolisthesis
- Trial name
- NCT03883022
- Testing
- with U-VANCO (vancomycin hydrochloride), without U-VANCO (vancomycin hydrochloride)
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Drug Effect, Rib Fractures
Trial of Injected Liposomal Bupivacaine vs Bupivacaine Infusion After Surgical Stabilization of Rib Fractures
Rib fractures represent a common injury pattern this is highly associated with patient morbidity and mortality, as pain control remains a challenge.
- Conditions
- Drug Effect, Rib Fractures, Rib Trauma, Surgical Procedure, Unspecified
- Trial name
- NCT03305666
- Testing
- Liposomal bupivacaine injection, Bupivacaine indwelling catheter
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Denver Health and Hospital Authority
Surgical Site Infection, Beta-lactam Allergy
Prophylactic Antibiotics for Surgical Site Infections and Beta-Lactam Allergy
Postoperative surgical site infection (SSI) is associated with unnecessary use of heath care resources including prolonged hospitalization and increased hospital readmission.
- Trial name
- NCT04401553
- Testing
- cephalosporin, Second tier antibiotic (Vancomycin)
- Sponsor
- University of Texas Southwestern Medical Center
Intraabdominal Abscess, Wound Infection
Appendectomy in Children Performed by Residents in the Era of Laparoscopic Surgery
Introduction: An increasing proportion of childhood appendicitis is treated with laparoscopic appendectomy (LA). The investigators wanted to elucidate the outcome of childhood appendicitis treated primarily by residents in a…
- Trial name
- NCT01657565
- Where
- Denmark
- Volunteers
- 390 people
- Sponsor
- Odense University Hospital
Wound Infection, Gynecologic Cancer
Prophylactic Negative Pressure Wound Therapy (VAC) in Gynecologic Oncology (G.O.)
A prospective controlled randomized study aimed to prospectively evaluate, the impact and effectiveness of clean incision prophylactic vacuum negative pressure therapy on wound healing (ciNPWT) in women at high risk of developing…
- Trial name
- GO-VAC (NCT04584957)
- Testing
- VAC therapy
- Where
- Italy
- Volunteers
- 196 people
- Sponsor
- Catholic University of the Sacred Heart
Skin Cancer
ObservAtional Study to Investigate Surgical Site Infection in Ulcerated Skin Cancers
The investigators aim to recruit 311 participants to this study from three UK Dermatology departments. The investigators will invite people with suspected skin cancers whose lesions have a broken surface (also known as ulcerated)…
- Trial name
- OASIS (NCT03782727)
- Where
- 3 sites in United Kingdom
- Volunteers
- 148 people
- Sponsor
- Cardiff and Vale University Health Board
Postoperative Complications, Surgical Wound Infection
Acupuncture and Post-Surgical Wound Healing
The purpose of this study is to determine if acupuncture improves wound healing. Since we, the investigators at the University of California, San Francisco (UCSF), know that how much oxygen is delivered to tissue is the best…
- Conditions
- Postoperative Complications, Surgical Wound Infection, Surgical Wound Dehiscence
- Trial name
- NCT00260494
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, San Francisco
Colorectal Surgery
Safety and Efficacy of One Dose Prophylactic Antibiotic in Laparoscopic Colorectal Surgery
In colorectal surgery, the use of prophylactic antibiotics is recommended. The standard use of antibiotics for colorectal surgery is three doses.
- Trial name
- NCT01220661
- Testing
- Cefotetan
- Where
- South Korea
- Volunteers
- 312 people
- Sponsor
- National Cancer Center, Korea
Antibiotic, Bowel Cancer
Mechanical Bowel Preparation With or Without Oral Antibiotics for Colorectal Cancer Surgery
Investigation of the role of adding oral antibiotics to preoperative mechanical bowel preparation before colorectal surgery for cancer.
- Conditions
- Antibiotic, Bowel Cancer, Colorectal Cancer, Surgical Site Infection
- Trial name
- MECCA (NCT03563586)
- Testing
- Bowel Preparation plus antibiotics, Bowel Preparation
- Where
- Greece
- Volunteers
- 210 people
- Sponsor
- National and Kapodistrian University of Athens
Mediastinitis
Delayed Primary Versus Late Secondary Wound Closure in Sternum Infections
Sternal osteomyelitis and poststernotomy mediastinitis is a severe and life-treating complication after the cardiac surgery. The incidence of sternal osteomyelitis ranges from 1% to 3% with a high mortality rate from 19% to 29% .
- Trial name
- NCT01473979
- Testing
- Surgical closure of the poststernotomy wound infection
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Lausanne Hospitals
Surgical Wound Infection
Prophylactic NPWT to Reduce SSI in Colorectal Surgery
The purpose of this study is to see if the Negative Pressure Wound Therapy (NPWT) system is effective and safe for the prevention of superficial and deep incisional surgical site infections (SSI) in high risk patients within 30…
- Trial name
- NCT03661814
- Testing
- Prevena
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Surgical Site Infection
Comparative Study of Postoperative Surgical Site Infections in Diabetic and Non-Diabetic Patients
This prospective observational study aims to compare the incidence and characteristics of postoperative surgical site infections (SSIs) between diabetic and non-diabetic patients undergoing elective general surgical procedures.
- Trial name
- NCT07049614
- Testing
- Diabetic Patients, Non-Diabetic Patients
- Where
- Pakistan
- Volunteers
- 132 people
- Sponsor
- Superior University
Surgical Site Infection
One Stage Versus Two Stage For Periprosthetic Hip And Knee Infection
The purpose of this study is to compare the outcomes of two different treatment options commonly used to manage periprosthetic joint infection (PJI), an infection around the artificial knee or hip.
- Trial name
- NCT02734134
- Testing
- One-stage exchange joint replacement surgery, Two-stage exchange joint replacement surgery
- Where
- 5 sites in United States
- Volunteers
- 343 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Cardiac Surgery, Infection, Postoperative Wound
Management Practices and the Risk of Infection Following Cardiac Surgery
The purpose of the study is to determine the best ways to prevent infections after heart surgery. Participation in the study will last at most 3 months after heart surgery.
- Conditions
- Cardiac Surgery, Infection, Postoperative Wound, Postoperative Wound Infection, Infections, Nosocomial
- Trial name
- NCT01089712
- Where
- 10 sites in United States, Canada
- Volunteers
- 5,158 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Skin Lesion
The Effect of Prophylactic Antibiotics on Surgical Site Infection Lower Limb Skin Excisions
The incidence of surgical site infection (SSI) infection in clean dermatologic surgery is very low, between 1-3%. Studies have demonstrated a much higher infection rate in skin excision surgeries in the lower limbs, up to 10% in…
- Trial name
- NCT03357419
- Testing
- Cephalexin
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Surgical Site Infections, Nosocomial Infection
Nasal Photodisinfection in All Patients Presenting for Surgery for a Wide Range of Surgical Procedures
This is a Phase 2 single-center, open-label, single-arm, study of a microbiological endpoint using antimicrobial photodynamic therapy (aPDT) for nasal disinfection in all patients (universal) presenting for surgery at an acute…
- Conditions
- Surgical Site Infections, Nosocomial Infection, Healthcare Associated Infections
- Trial name
- BENEFIT-PDT (NCT05090657)
- Testing
- methylene blue 0.01%/chlorhexidine gluconate 0.25% + light activation
- Where
- United States
- Volunteers
- 322 people
- Sponsor
- Ondine Biomedical Inc.
Surgical Site Infection
Reducing Wound Infections Using Bioelectric Wound Dressings
The purpose of this study is to compare the outcomes of using Bioelectric wound dressing on the pre-operative wound site and post operatively and compared it outcomes to the standard of care chlorhexidine skin preparation.
- Trial name
- JumpStart (NCT06312267)
- Testing
- Bioelectric dressing
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- AdventHealth
Surgical Procedure, Unspecified
A Trial to Evaluate Negative Pressure Incision Management System for Groin Wounds in Vascular Surgery Patients
The purpose of this research study is to investigate if a new negative pressure incision (surgical cut) management system, could reduce the occurrence of groin wound infections after vascular surgery.
- Trial name
- NCT02399111
- Testing
- Prevena Incision Management System
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Northwell Health
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