Clinical trials: Infection Surgical Wound
ExtraCorporeal Life Support (ECLS), Wound Infection
Investigating the Impact of Cold Atmospheric Plasma Treatment on Wound Healing at Cannulation Sites in Patients Following Extracorporeal Life Support
This study aims to evaluate a new wound treatment called cold atmospheric plasma (CAP) for patients receiving extracorporeal life support (ECLS).
- Conditions
- ExtraCorporeal Life Support (ECLS), Wound Infection, Surgical Site Infection, Delayed Wound Healing
- Trial name
- NCT07501897
- Testing
- Cold Atmospheric Plasma (CAP) Therapy, Standard wound care
- Where
- Taiwan
- Volunteers
- 65 people
- Sponsor
- National Taiwan University Hospital
Surgical Wound Infection, Thyroid Nodule
Comparing Efficacy of Postoperative Oral Antibiotic Use in Trans-Oral Thyroidectomy
Transoral endoscopic thyroid surgery is a emerging surgical technique for thyroid surgery. This study to investigate the need for postoperative antibiotics in transoral endoscopic thyroid surgery.
- Trial name
- POTO (NCT03295955)
- Testing
- Amoxicillin Clavulanate
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Orthopaedics Wound Dressings
Comparative Efficacy of Advanced and Traditional Wound Dressings in Post-Operative Orthopedic Care
Title: Comparative Efficacy of Advanced and Traditional Wound Dressings in Post-Operative Orthopedic Care: A Randomized Controlled Trial Objective: The primary objective of this study is to evaluate and compare the efficacy of…
- Trial name
- NCT06540040
- Testing
- Aquacel Ag, OPSITE, MEPILEX POST OP BORDER
- Where
- India
- Volunteers
- 320 people
- Sponsor
- Nidhi Srivastava
Spine Infection
Effectiveness of Povidone-Iodine Versus Chlorhexidine Gluconate Solutions in Reducing Microbial Contamination in Spinal Surgery Wounds During Intraoperative Soaking.
This study aims to assess the efficacy of intraoperative wound irrigation with iodine-containing and chlorhexidine-containing solutions in reducing bacterial colonization during spine surgery, and to determine which solution is…
- Trial name
- NCT06284174
- Testing
- Povidone-iodine solution; chlorhexidine gluconate
- Where
- Taiwan
- Volunteers
- 105 people
- Sponsor
- National Cheng-Kung University Hospital
Surgical Site Infection, Superficial Surgical Site Infection
Clipping Versus No Hair Removal and the Risk of Surgical Site Infections
The objective of this study is to determine whether hair clipping is non-inferior to no hair removal in preventing superficial, deep, and organ space surgical site infections (SSI) in patients undergoing various general surgical…
- Conditions
- Surgical Site Infection, Superficial Surgical Site Infection, Deep Surgical Site Infection, Organ/Space Surgical Site Infection
- Trial name
- NCT00975377
- Testing
- Hair clipping
- Where
- United States
- Volunteers
- 1,678 people
- Sponsor
- Gundersen Lutheran Medical Foundation
Wound Closure Technique, Wound Dehiscence, Surgical
Comparison of Cosmetic Outcome and Patient Satisfaction Between Staples and Suture Technique for Wound Closure Following Upper Limb Surgeries
Surgical wound closure is an essential component of postoperative care that influences wound healing, infection rates, cosmetic appearance, and patient satisfaction.
- Trial name
- NCT07633977
- Testing
- Staples, Sutures
- Where
- Nepal
- Volunteers
- 80 people
- Sponsor
- Kathmandu University School of Medical Sciences
Peritonitis, Postoperative Complications
Intravenous Immunoglobulin in Combination Therapy With Antibacterial Agents for SSI of the Lower Digestive Tract
The purpose of this study is to assess the clinical usefulness of IVIG in combination therapy with antibacterial agents for severe peritonitis after lower digestive tract surgery.
- Trial name
- NCT00511212
- Testing
- intravenous immunoglobulin
- Where
- Japan
- Volunteers
- 60 people
- Sponsor
- Multicenter Clinical Study Group of Osaka, Colorectal Cancer Treatment Group
Surgical Site Infection, Surgical Wound Infection
ROSSINI 2 - Reduction of Surgical Site Infection Using Several Novel Interventions
ROSSINI 2 is a phase III, multi-arm, multi-stage (MAMS) pragmatic, blinded (patient and outcome assessor), multicentre, randomised controlled trial (RCT) with an internal pilot, to evaluate the use of several in-theatre…
- Conditions
- Surgical Site Infection, Surgical Wound Infection, Surgery--Complications, Surgery
- Trial name
- ROSSINI 2 (NCT03838575)
- Testing
- 2% alcoholic chlorhexidine skin prep (SKIN PREP), Iodophor Antimicrobial Incise Drapes (DRAPE), Gentamicin-impregnated implants/ sponges (SPONGE)
- Where
- 2 sites in United Kingdom
- Volunteers
- 6,610 people
- Sponsor
- University of Birmingham
Abscess, Cellulitis
Aquacel Versus Iodoform Gauze for Filling Abscess Cavity Following Incision and Drainage
This study compares Aquacel against routine Iodoform packing for packing abscess cavities after incision and drainage. It is hypothesized that Aquacel will produce speedier healing of the abscess.
- Trial name
- NCT00984022
- Testing
- Type of dressing - Iodoform, Type of dressing - Aquacel
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Valleywise Health
Surgical Site Infection
Utility of Single-dose Oral Antibiotic Prophylaxis in Prevention of Surgical Site Infection in Dermatologic Surgery
The purpose of the study is to assess the effectiveness of a single dose of preoperative antibiotic in reducing surgical site infections in certain dermatological procedures.
- Trial name
- NCT04580472
- Testing
- Cephalexin
- Where
- United States
- Volunteers
- 574 people
- Sponsor
- Carilion Clinic
Stomach Neoplasms
No Antimicrobial Prophylaxis for Laparoscopic Distal Gastrectomy
The aim of this study is to evaluate the feasibility and safety of no use of antimicrobial prophylaxis during laparoscopic distal gastrectomy for gastric carcinoma.
- Trial name
- KSWEET-01 (NCT02200315)
- Testing
- No Antimicrobial prophylaxis
- Where
- 3 sites in South Korea
- Volunteers
- 98 people
- Sponsor
- Korean South West East Gastric Surgery Group
Infections
Role of Oxidized Regenerated Cellulose (ORC) Applied to "Dirty" Surgical Wounds
The purpose of this study is to determine whether oxidized regenerated cellulose (ORC) is effective to reduce the risk of surgical site infections (SSI).
- Trial name
- ORC (NCT00947089)
- Testing
- oxidized regenerated cellulose (Fibrillar SURGICEL), iodoform gauze
- Where
- Italy
- Volunteers
- 98 people
- Sponsor
- Catholic University of the Sacred Heart
Wound Infection Due to Staphylococcus Aureus, MRSA Infection of Postoperative Wound
S. Aureus Screening and Decolonization
Staphylococcus aureus (SA) healthcare-associated infections (HAI) cause significant morbidity and mortality. SA causes 15% of all HAI and 30% of surgical site infections (SSIs).
- Trial name
- NCT02182115
- Testing
- antiseptic bundle, standard of care
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Wound Complication
Cesarean Skin Incision Trial
The purpose of this study is to determine if there is a difference between Pfannenstiel and midline vertical skin incision at time of cesarean section in preventing wound complications in the morbidly obese patient.
- Trial name
- C-SIT (NCT01897376)
- Testing
- Pfannenstiel incision, vertical skin incision
- Where
- 2 sites in United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Wound Healing, Patient Comfort
Aquacel Compared to Traditional Post Surgical Wound Dressing in Vascular Surgery Patients
The study is a prospective randomised, controlled study of 136 patients undergoing vascular surgery. Their closed wounds were covered with either aquacel, a hydrofiber dressing, or a traditional gauze dressing.Number of changes…
- Trial name
- NCT00428623
- Testing
- wound dressing
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Oral Infection
Prediction Model for Delayed Extubation of Tracheal Intubation in Patients With Maxillofacial Space Infection After Abscess Incision and Drainage Surgery
Retrospective exploration of the risk factors associated with mechanical ventilation and tracheal extubation twenty-four hours after abscess incision and drainage surgery in patients with maxillofacial space infection.
- Trial name
- Prediction mod (NCT06853808)
- Volunteers
- 400 people
- Sponsor
- Henan Provincial People's Hospital
Surgical Site Infection, Pancreaticoduodenectomy
Association of Cephalosporin Resistance and Surgical Site Infections in Patients Undergoing Pancreaticoduodenectomy
Preoperative biliary drainage predisposes the bile to be contaminated with bacteria of the duodenum. These bacteria colonizing the bile are a potential source for surgical site infections after pancreaticoduodenectomy and many…
- Conditions
- Surgical Site Infection, Pancreaticoduodenectomy, Biliary Tract Infection Bacterial
- Trial name
- NCT05581017
- Testing
- Preoperative biliary drainage
- Where
- Finland
- Volunteers
- 376 people
- Sponsor
- Helsinki University Central Hospital
Post Operative Surgical Site Infection
Supplemental Perioperative Oxygen to Reduce Surgical Site Infection After High Energy Fracture Surgery
The OXYGEN Study is a double blinded prospective randomized controlled trial that will compare the proportion of surgical site infections within 6 months in patients treated with Supplemental Perioperative Oxygen compared to…
- Trial name
- OXYGEN (NCT01798810)
- Testing
- Supplemental Perioperative Oxygen
- Where
- 2 sites in United States
- Volunteers
- 1,171 people
- Sponsor
- Major Extremity Trauma Research Consortium
Sepsis, Hip Fractures
The Association Between Preoperative Sepsis and the Mortality After Hip Fracture Surgery
The worldwide occurrence of hip fracture is high with an annual incidence of approximately 100 per 100.000 people. Mortality for patients undergoing hip fracture surgery is high with a 30-day mortality rate varying between 4.5…
- Trial name
- NCT03201679
- Testing
- Repair of hip fracture
- Volunteers
- 1,967 people
- Sponsor
- Bispebjerg Hospital
Surgical Site Infection
Study of Chlorhexidine Gluconate as a Preoperative Antisepsis
The purpose of this study is to determine which drug (chlorhexidine gluconate vs. povidone iodine) as a preoperative antisepsis in clean-contaminated abdominal surgery (liver, hepatobiliary, small or large bowel, stomach) is…
- Trial name
- CHG (NCT01495117)
- Testing
- Povidone-Iodine, Chlorhexidine gluconate
- Where
- South Korea
- Volunteers
- 534 people
- Sponsor
- Seung Duk Lee
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