Clinical trials: Infertility,Male
Male Infertility
A Pilot Study to Evaluate the Effect of Pomegranate Juice on Semen Parameters in Healthy Male Volunteers
How daily consumption of pomegranate juice affects the concentration, morphology or motility of sperm in healthy men.
- Trial name
- NCT01595308
- Testing
- Pomegranate juice
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- POM Wonderful LLC
Asthenozoospermia
The Effect of Oral Zinc Supplementation on Thiol Oxido-reductive Index
Although several studies have considered the relationship between infertility and semen thiol compounds levels, no study on the effects of asthenospermia treatments such as oral zinc supplementation on thiol related enzymes…
- Trial name
- NCT02985905
- Testing
- zinc sulfate
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- mahmoud hussein hadwan
Infertility, Non-obstructive Azoospermia
PET-MRI for Functional Imaging of the Testis: A Feasibility Study
The primary objective of this study is to explore feasibility of testis functionality assessment and testis imaging obtained from Positron Emissions Tomography (PET) /Magnetic Resonance Imagine (MRI).
- Conditions
- Infertility, Non-obstructive Azoospermia, Vasectomy
- Trial name
- NCT02669108
- Testing
- PET/ MRI of the Testis
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Male Infertility
Effect of Liver Cirrhosis on Semen Parameters and Reproductive Hormones
Normal testicular hormonal and spermatogenic function depends not only on the testis itself, but also on the integrity of the hypothalamus and anterior pituitary.
- Trial name
- NCT03167749
- Testing
- Laboratory test
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Male Infertility
A Clinical Evaluation of Semen Quality Using the MiOXSYS™ System 2.0
The purpose of this study is to determine if elevations in oxidative stress, as measured by oxidation-reduction potential (ORP), can distinguish between semen samples from men with abnormal semen parameters from those with normal…
- Trial name
- NCT02839447
- Testing
- Diagnostic
- Where
- 6 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aytu BioPharma, Inc.
Infertility, Male
Male Reproduction COVID Sequelae Study (MARCOS).
The purpose of this study is to investigate the effects of COVID-19 Vaccination on semen parameters and to determine how long these possible changes may last following vaccination.
- Trial name
- NCT04665258
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Male Infertility
Validation of New Devices Against Ambient Electromagnetic Radiation
Project Summary Cell phones have become indispensable devices in the investigator's daily life. These phones operate between 400 and 2000 MHz frequency bands and emit radiofrequency electromagnetic waves (EMW).
- Trial name
- NCT04541459
- Testing
- new device against ambient electromagnetic radiation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Waveguard GmbH
Male Infertility
Vitamin E and Male Infertility
The goal of this study is to determine whether there is a correlation between the levels of Vitamin E in sperm and sperm DNA fragmentation.
- Trial name
- NCT00178516
- Testing
- behavior, procedure
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Infertility, Vaginal Flora Imbalance
Evaluate the Use of a New Probiotic Strain in Couples With Fertility Problems and Dysbiosis.
Pilot study to evaluate the effect of the strain Lactobacillus PS11610 on the microbiota of the female and male genital tract in couples with fertility problems.
- Conditions
- Infertility, Vaginal Flora Imbalance, Genital Disorder
- Trial name
- PROFEC (NCT03701893)
- Testing
- Lactobacillus PS11610
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ProbiSearch SL
Male Infertility
Pilot Study on the Effects of FSH Treatment on the Epigenetic Characteristics of Spermatozoa in Infertile Patients With Severe Oligozoospermia
Single center, prospective, open clinical study to determine the genomic imprint (epigenetic modification) in a series of male infertility patients with alterations in their spermiogram (oligozoospermia) compared to a group of…
- Trial name
- NCT02605070
- Testing
- Bravelle
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Infertility, Female, Infertility
Oral Dydrogesterone (OD) Versus Micronized Vaginal Progesterone (MVP) for Luteal Phase Support (LPS) in IVF/ICSI
Female inability to conceive a child. The purpose of this prospective randomized, double-blinded, double dummy, two-arm cross-over study is to investigate the difference on histological, transcriptional and immunological level in…
- Conditions
- Infertility, Female, Infertility, Genital Diseases, Male, Genital Diseases, Female
- Trial name
- NCT03677336
- Testing
- Dydrogesterone Oral Tablet, Micronized progesterone
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CRG UZ Brussel
Severe Oligoasthenoteratozoospermia, Sperm Quality
PRP Improves Blastocyst Formation in ICSI Cycles
The goal of this clinical trial is to learn if platelet rich plasma (PRP) works to improve embryo development rates and embryo quality in IVF cycles, involving male adult patients with severe sperm disorders.
- Conditions
- Severe Oligoasthenoteratozoospermia, Sperm Quality, Spermatazoa Disorders, Sperm Parameters in Fertile and Infertile Men
- Trial name
- PRP ICSI SOAT (NCT07579858)
- Testing
- Platelet Rich Plasma
- Where
- Indonesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Stella Maris Women and Children Hospital
Infertility, Infertility, Female
GnRH Agonist at Embryo Transfer: IVF Outcomes
In ART (assisted reproductive technology) cycles, embryos are transferred to a woman's uterus after in-vitro fertilization (IVF) in a laboratory.
- Conditions
- Infertility, Infertility, Female, Infertility, Male
- Trial name
- GRAET (NCT03544073)
- Testing
- Saline Solution for Injection, Leuprolide Acetate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Male Infertility, Low Sperm Quality
A Clinical Trial to Evaluate the Effects of a Supplement on Markers of Male Fertility
This study will evaluate the effects of the WeNatal For Him supplement on markers of male fertility over a 3-month period. The trial is a single-arm, unblinded study enrolling 40 male participants who will take 3 capsules of the…
- Conditions
- Male Infertility, Low Sperm Quality, Low Testosterone, Low Energy
- Trial name
- NCT07740161
- Testing
- WeNatal For Him Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- WeNatal
Urologic Diseases, Urologic Cancer
Bank of Biological Material From Patients and Healthy Donors for the Study of Urological and Uro-oncological Pathologies
The project aims to collect fresh biological material derived both from surgical resections performed in diseases, neoplastic and otherwise, of urological relevance at the level of the prostate, bladder, kidney, testicle and…
- Conditions
- Urologic Diseases, Urologic Cancer, Infertility
- Trial name
- NCT06187870
- Testing
- Collection of biological data
- Where
- Italy
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Intracytoplasmic Sperm Injection, Infertility, Male
Outcome of Using Sperm Bound to the Zona Pellucida of Immature Oocytes for Intracytoplasmic Sperm Injection (ICSI)
In vivo, the zona pellucida (ZP) of the oocyte can bind to normally functional sperm. The ZP-sperm interaction is one of the final steps of natural selection during their journey in the female reproductive tract.
- Trial name
- NCT05724979
- Testing
- ZP-binding
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Male Infertility
Home Semen Analysis Tests As a Screening Tool for Fertility Patients
Infertility, defined as the inability to conceive after 12 months of regular unprotected intercourse, is estimated to affect 1 in 7 heterosexual couples.
- Trial name
- NCT06188936
- Testing
- ExSeed®, Survey
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Infertility, Female, Infertility, Male
Cell Free Preimplantation Genetic Testing
This study aims to develop preimplantation genetic testing methods from embryo culture media (cell free). Genetic testing of culture media will be compared to conventional methods based on embryo biopsies.
- Trial name
- NCT04628507
- Testing
- Spent media collection
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Genomic Prediction Inc.
Urologic Diseases, Male Infertility
Protocol N. 2014 - Observational Study on the Quality of Life of Outpatients
Prospective observational study on the quality of life of patients attending general urology, sexual medicine, reproductive medicine, functional urology, neuro-urology and uro-oncology clinics.The data relating to the clinical…
- Conditions
- Urologic Diseases, Male Infertility, Sexual Medicine
- Trial name
- NCT06193850
- Testing
- Observation during time
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Testicular Cancer
WEST-KOaST Study: WES Analysis of Testicular Cancer Patientsand Their First-degree Family Members
The project aims to identify the possible risk factors regarding the onset of the disease and to evaluate genes and gene modifications responsible for the onset od testicular cancer.
- Trial name
- West-KOaSt (NCT06142500)
- Testing
- Analysis of biological samples of saliva from testicular cancer patients and from their first-degree family members
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele