Clinical trials: Infertility,Male
Urologic Diseases, Male Infertility
Protocol N. 2014 - Observational Study on the Quality of Life of Outpatients
Prospective observational study on the quality of life of patients attending general urology, sexual medicine, reproductive medicine, functional urology, neuro-urology and uro-oncology clinics.The data relating to the clinical…
- Conditions
- Urologic Diseases, Male Infertility, Sexual Medicine
- Trial name
- NCT06193850
- Testing
- Observation during time
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Varicocele
Beneficial Effects of Microsurgical Varicocelectomy on Semen Parameters for Causes Other Than Infertility
The purpose of this study is to evaluate whether clinical varicoceles are associated with abnormal semen parameters and whether varicocelectomy could improve the semen parameter in patients unrelated with infertility.
- Trial name
- NCT02006316
- Testing
- Microsurgical subinguinal varicocelectomy
- Where
- South Korea
- Volunteers
- 121 people
- Sponsor
- Seoul National University Hospital
Infertility, Female, ART
Intracytoplasmic Sperm Injection in Non-male Factor Infertility in Advanced Maternal Age
This will be a prospective, randomized (1:1 ratio) clinical trial for non-male factor infertility in advanced maternal age with or without intracytoplasmic sperm injection(ICSI).
- Trial name
- NCT03120884
- Testing
- ICSI, IVF
- Where
- China
- Volunteers
- 1,422 people
- Sponsor
- International Peace Maternity and Child Health Hospital
Male Infertility
Small RNA Pathways in Mammalian Gametogenesis
Basic and clinical research is revealing that various noncoding and small RNAs play important and diverse roles in germ cell development and quality, including X/Y silencing during meiosis, gene regulation, DNA damage responses…
- Trial name
- NCT02864329
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Weill Medical College of Cornell University
Human Papilloma Virus, Infertility, Male
Detection and Prevalence of Human Papillomavirus (HPV) in Seminal Plasma and/or on Sperm in Men Undergoing Treatment With IVF/ICSI.
This observational study aims to investigate the presence of HPV DNA in semen samples from men undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment.
- Trial name
- NCT06161727
- Testing
- HPV exposure
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Vastra Gotaland Region
Infertility, Male Infertility
"System Medicine" Approach for Prevention Strategies for Comorbidities in Infertile Men
By applying a "system medicine" approach, the project aims to identify new biomarkers and/or prognostic tools aimed at developing personalized strategies to prevent the onset of comorbidities in infertile men.
- Trial name
- NCT06183255
- Testing
- Observation and evaluation of clinical parameters in the two cohorts
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS San Raffaele
Varicocele, Male Infertility
Effect of Varicocelectomy on Spermatogenic Cell Count and Semen Parameters
This study aims to evaluate how varicocele surgery (varicocelectomy) affects the number of immature sperm cells (spermatogenic cells) found in the semen of infertile men.
- Conditions
- Varicocele, Male Infertility, Infertility, Varicocelectomy
- Trial name
- NCT07684963
- Testing
- Subinguinal Microsurgical Varicocelectomy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Infertility, Male, Oxidative Stress
Menevit Study: Menevit Anti-Oxidant Therapy for the Treatment of Male Infertility
Oxidative stress related damage to sperm is believed to be a major cause of male infertility. The object of the Menevit study is to investigate the role of a novel anti-oxidant preparation (Menevit) on sperm function, embryo…
- Trial name
- NCT00100269
- Testing
- Menevit anti-oxidant
- Where
- Australia
- Volunteers
- 60 people
- Sponsor
- Repromed
Klinefelter Syndrome, Azoospermia
Sperm Production in Kleinfelter Syndrome Patients After Mesenchymal Stem Cell Injection
Klinefelter syndrome KS is caused by an additional X chromosome in males (47,XXY). Clinical findings are nonspecific during childhood; thus, the diagnosis commonly is made during adolescence or adulthood in males who have small…
- Trial name
- NCT02414295
- Testing
- Mesenchymal stem cell injection
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Man Clinic for Andrology, Male Infertility and Sexual Dysfunction
Infertility, Male
Effect of Ejaculatory Abstinence on Semen Parameters in Male Factor Infertility Patients
The purpose of this study is to compare semen parameters with in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) when male factor infertility patients abstain from ejaculation more than 48 hours (routine care)…
- Trial name
- NCT04206800
- Testing
- Ejaculatory abstinence less than 24 hours
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Boston IVF
Changes in sncRNA in Sperm, Male Fertility
The Effects of Diet on Small Non-coding RNA i Sperm Cells and the Possible Effects on Reproductive Success: Diet Intervention Effects on Sperm
In this study, patients with infertility treated with IVF at the Center of Reproductive Medicine in Linköping, Sweden, will receive recipes and food according to Nordic dietary guidelines.
- Conditions
- Changes in sncRNA in Sperm, Male Fertility, RNA Profile
- Trial name
- DIET-IS (NCT06831292)
- Testing
- Diet intervention NMR
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Ostergotland County Council, Sweden
Male Infertility
To Evaluate the Effect of Reveratrol,Folic Acid, Vitamin D, Vitamin B12 and B6 in Male Infertility
The objective of this study is to evaluate the impact of the Genante(TM) on the spermiogram parameters in infertile male patients
- Trial name
- NCT03864198
- Testing
- Genante
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- University Of Perugia
Male Infertility
Strategies for Reducing Sperm DNA Fragmentation in ICSI Semen Samples: a Prospective Randomized Controlled Trial
Comparing second ejaculate and physiological ICSI (PICSI) as strategies for improvement of abnormal sperm DNA fragmentation in patients undergoing ICSI.
- Trial name
- NCT04496232
- Testing
- PICSI, Second ejaculate
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Ganin Fertility Center
Infertility, Vaginal Flora Imbalance
Evaluate the Use of a New Probiotic Strain in Couples With Fertility Problems and Dysbiosis.
Pilot study to evaluate the effect of the strain Lactobacillus PS11610 on the microbiota of the female and male genital tract in couples with fertility problems.
- Conditions
- Infertility, Vaginal Flora Imbalance, Genital Disorder
- Trial name
- PROFEC (NCT03701893)
- Testing
- Lactobacillus PS11610
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- ProbiSearch SL
Male Infertility
Body Mass Index and Age Correlate With Antioxidant Supplementation Effects on Sperm Quality
Spermatozoa are vulnerable to lack of energy and oxidative stress as a result of elevated levels of reactive oxygen species. Therefore, it is essential that appropriate nutrients are available during maturation.
- Trial name
- NCT04177667
- Testing
- Proxeed
- Volunteers
- 104 people
- Sponsor
- University of Roma La Sapienza
Hypogonadism
A Study to Assess the Bioequivalence of Follitropin Alfa Solution in Pen and Follitropin Alfa Powder in Vial in Healthy Downregulated Male Participants
The purpose of this study is to assess the bioequivalence of Test and Reference in healthy downregulated male participants. This is a 2-sequence, 2-period study using the following treatment sequences across Study Periods 1 and…
- Trial name
- NCT07097259
- Testing
- Test: Follitropin alfa, Reference: Follitropin alfa, Zoladex
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- EMD Serono Research & Development Institute, Inc.
Asthenozoospermia
The Effect of Oral Zinc Supplementation on Thiol Oxido-reductive Index
Although several studies have considered the relationship between infertility and semen thiol compounds levels, no study on the effects of asthenospermia treatments such as oral zinc supplementation on thiol related enzymes…
- Trial name
- NCT02985905
- Testing
- zinc sulfate
- Where
- Iraq
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- mahmoud hussein hadwan
Male Infertility
Spermatogonial Stem Cells in Azoospermic Patients: a Comparison Between Obstructive and Non-obstructive Azoospermia
The researchers hypothesized that nonobstructive azoospermia might be associated with a reduction OF SSCs in seminiferous tubules as compared with obstructive azoospermia.
- Trial name
- NCT01178463
- Testing
- Biospecimen staining
- Where
- Israel
- Volunteers
- 25 people
- Sponsor
- Hillel Yaffe Medical Center
Male Infertility, Sperm DNA Fragmentation
Microfluidics Versus Density Gradient Centrifugation for Sperm Preparation in IVF
This randomized controlled trial aimed to compare the effectiveness of microfluidic sperm sorting and density gradient centrifugation (DGC) in reducing sperm DNA fragmentation index (DFI) and improving clinical outcomes in IVF.
- Conditions
- Male Infertility, Sperm DNA Fragmentation, In Vitro Fertilization (IVF)
- Trial name
- MCvsDGC (NCT07004309)
- Testing
- Microfluidic sperm sorting, Density Gradient Centrifugation
- Where
- Vietnam
- Volunteers
- 119 people
- Sponsor
- Hanoi Medical University
Male Infertility, Male Hypogonadism
Relationship of the Microenvironment and Male Fertility
Although much is known about the microenvironment of the gut and the vagina, very little has been published on the microenvironment of the seminal plasma.
- Trial name
- NCT04704141
- Testing
- Hormone replacement therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Illinois Chicago