Clinical trials: Infertility/Sterility
Sexual Dysfunction, PCOS
Sexual Dysfunction in Infertile Women With PCOS Undergoing Fertility Treatment
Infertility, defined as the inability to become pregnant after one year of regular unprotected sexual intercourse. It is estimated that around 20 % of couples suffer from infertility with prevalence rates of infertility differing…
- Trial name
- NCT05402800
- Testing
- FSFI questionnaire
- Where
- Egypt
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Cairo University
Infertility, Female
Exploratory Study Assessing Synchronisation of Egg Sacs With Degarelix
The main purpose of this clinical research study is to investigate if degarelix can synchronise the growth of the egg sacs in the ovaries and if degarelix has any effect on the lining of the womb.
- Trial name
- NCT00434122
- Testing
- Degarelix mid-luteal, 2.5 mg
- Where
- 4 sites in Belgium, Czechia and 1 more
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Uterine Fibroid, Pregnancy Complications
Pregnancy Outcomes Following Myomectomy
The most prevalent genital pathology, uterine fibroids have a detrimental impact on the health of women. Fibroid symptoms are typically more impactful on females and frequently require uterine excision.
- Conditions
- Uterine Fibroid, Pregnancy Complications, Reproductive Issues, Reproductive Sterility
- Trial name
- NCT06474065
- Testing
- Myomectomy
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Semen Quality
Sperm Quality in Consecutive Sperm Samples After 4-7 Days and 2 Hours of Sexual Abstinence
The main purpose of the study is to assess to which degree a series of sperm parameters known to be associated with fertilization and implantation potential in artificial reproductive technology (ART) differ in consecutive sperm…
- Trial name
- NCT02667080
- Testing
- 2-7 days of Sexual abstinence, 2 hours of sexual abstinence
- Where
- Denmark
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Infertility
Infertility Markers in Serum, Urine, and Follicular Fluid
This study is only collecting specimens from current patients of PENN Fertility Care. The purpose of this investigation is to assess if markers of oxidative stress that are known to be associated with other medical conditions can…
- Trial name
- NCT00194220
- Where
- United States
- Volunteers
- 1,235 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Infertility
Screening of Low Responders for Aneuploidy to Improve Reproductive Efficiency
The purpose of this study is to assess the impact of Comprehensive Chromosome Screening(CCS) on patients with low ovarian reserve in an effort to improve success during in vitro fertilization and decrease the time to successful…
- Trial name
- Solaire (NCT01977144)
- Testing
- Comprehensive Chromosomal Screening
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility, Intrauterine Insemination
Personalized Insemination Treatment Study
This study is intended for women undergoing their first cycle of 3 intrauterine inseminations. All 3 inseminations will be personalized by using algorithms to determine the dose of study medication.
- Conditions
- Infertility, Intrauterine Insemination, Reproduction
- Trial name
- PITS (NCT03830723)
- Testing
- Follitropin delta
- Where
- Canada
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Clinique Ovo
Infertility, Female, First Trimester Spontaneous Abortion
Determination of Circulating Placental Biomarkers Levels to Predict the Pregnancy Outcome of First Trimester After IVF.
This study will assess the predictive potential of circulating placental biomarkers for spontaneous miscarriage within the following month in an IVF setting.
- Trial name
- NCT04387994
- Testing
- Blood samples collection
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Infertility, Female
Ibuprofen Versus Ketorolac for Pain Relief During Hysterosalpingogram
Hysterosalpingogram (HSG) testing is a vital part of the workup for infertility patients. It is often noted to be biggest pain that patients undergo during the workup.
- Trial name
- NCT05190341
- Testing
- Ibuprofen 800 mg oral, Ketorolac 30mg oral
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Madigan Army Medical Center
Sterility, Female, Contraception
Real World Effectiveness and Safety of Hysteroscopic (Essure®) Compared to Laparoscopic Sterilization
More than 345,000 U.S. women undergo either tubal ligation ("getting her tubes tied") or Essure procedures each year to permanently avoid pregnancy.
- Conditions
- Sterility, Female, Contraception, Contraceptive Device; Complications
- Trial name
- NCT03438682
- Testing
- Essure, Laparoscopic sterilization, Intrauterine Device (IUD)
- Where
- United States
- Volunteers
- 89,203 people, healthy volunteers welcome
- Sponsor
- Yale University
Infertility Female
IVM for Patients With Low Ovarian Response. Does it Improve IVFoutcomes and Does it Improve the Following IVF Cycle?
Poor ovarian response (POR) is one of the major therapeutic challenges in in vitro fertilization. Several therapeutic approaches for POR have been explored; yet, a single effective strategy has not yet been established.
- Trial name
- NCT02498210
- Testing
- In Vitro Maturation Procedure
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Covid19, Fertility Issues
Semen Analysis Parameters Following Pfizer's COVID-19 Vaccine
In this study the investigators will explore the effect of the BNT162b2 COVID-19 Vaccine on semen analysis parameters among 75 fertile men.
- Trial name
- NCT04778033
- Testing
- Sperm collection
- Where
- Israel
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility
Frozen Embryo Donation Study
The purpose of this study is to improve patient understanding of and interest in donating frozen embryos resulting from in vitro fertilization (IVF) to others undergoing infertility treatment.
- Trial name
- FREDS (NCT01883934)
- Testing
- Enhanced clinic-based support/counseling, Control
- Where
- United States
- Volunteers
- 3,568 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Infertility
Comparison of Transfers of Thawed Blastocysts Versus Blastocysts Derived From Thawed Bipronuclear Oocytes
The purpose of this study is to determine if cryopreservation at the blastocyst stage followed by embryo thaw and transfer is as effective as cryopreservation of bipronuclear oocytes followed by post-thaw extended culture (PTEC)…
- Trial name
- NCT01247987
- Testing
- Blastocyst cryopreservation, Bipronuclear oocyte cryopreservation
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Bruce Shapiro M.D.
Infertility, Female
Automated Intracytoplasmic Sperm Injection (ICSIA)
The purpose of this research study is to evaluate Overture's automated Intracytoplasmic Sperm Injection (ICSIA) System. ICSIA is an investigational medical device that automates injection of sperm into eggs.
- Trial name
- ICSIA (NCT05633316)
- Testing
- Investigational device named ICSIA, Manual ICSI
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Overture Life
Infertility Female, Zonulin
Effect Of The Mediterranean Diet On Zonulin And Infertility
The goal of this clinical trial is to learn if mediterranean diet works to treat infertility in women. It will also learn about the initial and end of study zonulin levels of mediterranean diet and control group.
- Conditions
- Infertility Female, Zonulin, Intestinal Permeability, Mediterranean Diet
- Trial name
- NCT07072936
- Testing
- mediterranean diet
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- SINEM BAYRAM
Infertility
Mapping the Endocrine Determinants of Ovarian Stimulation to Optimize Outcomes in Fresh Embryo Transfer Cycles
The goal of this project is to identify autocrine, paracrine and endocrine factors which are associated with intercycle variation in cyclical follicle recruitment.
- Trial name
- RIOT-B (NCT02939898)
- Testing
- Letrozole
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Sven O. Skouby
Infertility
Optimizing Patient Analgesic Experience During IVF
This study is for patients undergoing In Vitro Fertilization (IVF). The investigators are studying the best way to control pain during the egg retrieval process.
- Trial name
- NCT01814657
- Testing
- Lidocaine hydrochloride (HCl) 1% solution, Sterile Normal Saline%
- Where
- Canada
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of Alberta
IVF, Fertility Issues
Comparison of Progestin Primed Ovarian Stimulation (PPOS) vs.GnRH Antagonist Methods on IVF Outcomes
The goal of this randomized clinical trial is to compare the effects of two different ovarian stimulation methods: Progestin Primed Ovarian Stimulation (PPOS) vs. GnRH Antagonist in embryologic outcomes of IVF Patients.
- Conditions
- IVF, Fertility Issues, Infertility
- Trial name
- NCT06396390
- Testing
- Progestin, GnRH antagonist
- Where
- Turkey (Türkiye)
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Nesta Clinic
Infertility
Effect of Vitamin D Status on Clinical Pregnancy Rates Following Intra Cytoplasmic Sperm Injection
All patients will undergo in vitro fertilization. Serum 25 (OH) D samples will be collected within1 week before oocyte retrieval.
- Trial name
- NCT02987478
- Where
- Egypt
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
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