Clinical trials: Infertility/Sterility
Infertility, Female, Infertility
Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst?
To investigate, whether on the day of egg retrieval, after ovarian stimulation for ICSI (intracytoplasmic sperm injection), there is a correlation between the intrafollicular AMH (Anti-Müllerian hormone) levels and the ploidy…
- Trial name
- NCT05837325
- Testing
- Oocyte Pick Up - Out of Study, Denudation - Out of Study, ICSI
- Where
- United Arab Emirates
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility
The Role of Massage in Increasing Total Motile Sperm Count of IUI
The purpose of this prospective, randomized study, was to determine if neck and shoulder massage performed within 15 minutes of semen sample collection will increase the semen volume, and therefore increase the total motile sperm…
- Trial name
- NCT01969825
- Testing
- Massage
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Infertility
Gene Expression Analysis of the Endometrium After Endometrial Biopsy in Fertile Women
The aim of this study is to evaluate the gene expression of the endometrium after an endometrial biopsy in fertile women using Next Generation Sequencing of total RNA.
- Trial name
- NCT02219425
- Testing
- endometrial biopsy
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Infertility
Injection of Hormone to Enhance Implantation in Embryo Transfer After IVF
The endometrium is deprived of signals form the embryo in IVF conditions. Studies suggest that placing HCG into the uterus prior to embryo transfer can enhance implantation.
- Trial name
- NCT01986374
- Testing
- HCG is introduced
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Servy Massey Fertility Insititute
Infertility, Female
Comparison of in Vitro Fertilization Rates of Oocytes and Embryo Development Using Two Techniques of Semen Processing
The investigators propose to assess one method of sperm selection based on the characteristics of spermatozoa recently introduced: Sperm Selection Assay, which used a gradient of concentration of progesterone to act as…
- Trial name
- NCT03186170
- Testing
- SSA sperm selection
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Infertility of Uterine Origin, Implantation Failure
International Non-selection Study for ERA® Test in Patients With Previous Implantation Failures
Women´s period comprises different hormonal stages, being one of them the stage for maximum receptivity and proper embryo implantation.
- Trial name
- NCT06097559
- Testing
- Endometrial fluid and biopsy collection
- Where
- 8 sites in Argentina, Panama and 2 more
- Volunteers
- 738 people, healthy volunteers welcome
- Sponsor
- Igenomix
Amenorrhea, Dysmenorrhea
Reproductive Effects of Pesticide, PCB and Mercury Exposure in Laotian Immigrants
This project is examining the reproductive effects of exposure to certain compounds that are suspected to act on the endocrine system, e.g. they may act like or interfere with hormones such as estrogen.
- Conditions
- Amenorrhea, Dysmenorrhea, Oligomenorrhea, Anovulation
- Trial name
- NCT00011388
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
IVF, Body Weight
Nutritional Status of Women Undergoing in Vitro Fertilization
Infertility affects around 15 % of couples in their reproductive years. Even though the use of assisted reproductive technologies (ART) in aforementioned couples is increasing, their success rate is still relatively low.
- Conditions
- IVF, Body Weight, Nutrient Deficiency, Dietary Vitamin B12 Deficiency Anemia
- Trial name
- NCT05865015
- Where
- 2 sites in Slovenia
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Infertility
Improving Knowledge About Infertility; an Online Educational Tool
The purpose of this study is to determine the effectiveness of an online informational video in improving knowledge about infertility in couples experiencing problems conceiving.
- Trial name
- NCT01916356
- Testing
- educational video
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Queen's University
Infertility
Online Mind/Body Program for Fertility
This pilot-study assesses the feasibility and acceptability of an Online Mind/Body Fertility Program, designed to help individuals and/or couples cope with the physical and emotional impact of infertility by learning special…
- Trial name
- NCT03343405
- Testing
- Online Mind/Body Program for Fertility
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Infertility, Female
The Potential Effects of Inofolic Plus on Abnormal Ovarian Reserve Parameters in Subfertile Women
Dr. Roseff and his colleagues are conducting a study to evaluate the effectiveness of a novel substance (Inofolic Plus®) in improving oocyte (egg) parameters in subfertile female patients, as measured through Anti-Mullerian…
- Trial name
- NCT01290432
- Testing
- Inofolic Plus
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Palm Beach Center for Reproductive Medicine
Infertility
Ulipristal Acetate on Progesterone Levels and Glycodelin-A Endometrial Pattern
Controlled ovarian stimulation (COS) for FIV increases progesterone (P) and estradiol (E2) serum levels in supraphysiologic concentrations at the end of follicular phase.
- Trial name
- NCT01391845
- Testing
- ulipristal acetate
- Where
- Argentina
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Programa de Asistencia Reproductiva de Rosario
Female Infertility
Looking for a Blood Epigenetic Signature to Predict Female Infertility
The present research project aims to study the DNAm mechanisms underlying the reduction of fertility due to the progressive depletion of oocyte quality.
- Trial name
- FIB_CARIPLO (NCT06098495)
- Testing
- search for epigenetic profile of infertility
- Where
- Italy
- Volunteers
- 1,456 people, healthy volunteers welcome
- Sponsor
- Università Vita-Salute San Raffaele
Infertility
Single-step Versus Sequential Media in Preimplantation Embryo Development and Pregnancy Rates
Sequential culture media were introduced in order to meet the changing requirements of the developing embryo in vitro. However, there has been renewed interest in the use of single-step media, which allow the embryo itself to…
- Trial name
- NCT02048527
- Testing
- Global, Origio
- Where
- Greece
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Eugonia
Primary Female Infertility, Secondary Female Infertility
Effect of Traditional Chinese Medicine on In Vitro Fertilization (IVF) Success Rates
The purpose of this study is to determine the value of combining Traditional Chinese Medicine (TCM) Protocols including acupuncture with In Vitro Fertilization (IVF).
- Trial name
- TCM-P002 (NCT01331395)
- Testing
- Traditional Chinese Medicine
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Pacific Fertility Center
Infertility
The Effect of Follicular Flushing on Oocyte Retrieval Rate and Embryo Quality
Researchers will investigate the effect of flushing according to follicle size on the success of obtaining oocytes from a single follicle.
- Trial name
- NCT05584436
- Where
- Turkey (Türkiye)
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Women Infertility
"Magnetic Resonance Imaging Hysterosalpingography for the Integral Evaluation of the Infertile Patient."
Abstract: Recent advances in reproductive medicine have generated a demand for more accurate imaging methods for identifying the specific cause of female infertility and other gynecologic disorders.
- Trial name
- HSG-RM (NCT02398630)
- Testing
- TC Virtual Hysterosalpingography, MRI Virtual Hysterosalpingography, Antimullerian Hormone dosing
- Where
- Argentina
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Diagnostico Maipu
Infertility
Double and Single Intrauterine Insemination In Controlled Ovarian Stimulation (COH) Cycles With Multifollicular Development
Our hypothesis is double insemination will improve pregnancy rates in coh cycles with more than one dominant follicles (>16mm).
- Trial name
- NCT00993902
- Testing
- Intrauterine insemination (single), Double intrauterine insemination
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Baskent University
Secondary Infertility
Non-invasive Preimplantation Genetic Testing for Aneuploidies Using Cell-free DNA in Spent Culture Media
Analysis of embryonic cell-free DNA (cfDNA) present in the spent culture media (SCM) is a non-invasive alternative for preimplantation genetic testing for aneuploidies (PGT-A) that avoids the technical challenges and limitations…
- Trial name
- niPGT-A (NCT04711239)
- Testing
- PGT-A / niPGT-A
- Volunteers
- healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility
Next Generation DNA Sequencing in Patients With Idiopathic Male Infertility
Hypothesis: To identify new gene mutations that can be related to patients with idiopathic male factor infertility. Primary Objective: To detect possible genetic abnormalities in families with more than one sibling with male…
- Trial name
- NCT02021721
- Where
- Qatar
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
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