Clinical trials: Infertility
Infertility
A Study of the Efficacy and Safety of Highly Purified Menotrophin Versus Recombinant Follitropin Alfa
Prospective open label, randomised, parallel group, comparative pilot.
- Trial name
- NCT00257556
- Testing
- Menotrophin, Follitropin alfa
- Where
- 6 sites in Germany, United Kingdom
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
IVF
Speculum Insertion During Embryo Transfer
Lubrication gels are widely used in numerous gynecologic procedures in order to ease the insertion of speculum and visualize the cervix.
- Trial name
- NCT06210451
- Testing
- Sterile water-based gel
- Where
- Israel
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Fertility Issues, Nutrition, Healthy
Food Intake and Epigenetic Alteration in the Spermatozoa of Singletons and Twins
The purpose of this study is to elucidate the role of acute dietary intake in male populations, and its impact on spermatozoa quality, integrity, content and epigenetic programming.
- Conditions
- Fertility Issues, Nutrition, Healthy, Epigenetic Disorder, Overnutrition
- Trial name
- FEASST (NCT05368194)
- Testing
- Isocaloric Unprocessed Diet, Isocaloric Processed Diet, Excess Calorie Unprocessed Diet
- Where
- Denmark
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Infertility
Automated Sperm Sample Preparation Protocol
This clinical trial would be directed at determining the effectiveness of an innovative sperm sample preparation protocol for intrauterine insemination (IUI).
- Trial name
- NCT03999762
- Testing
- sample prep
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nanonc Inc.
Male Infertility
A Clinical Evaluation of Semen Quality Using the MiOXSYS™ System 2.0
The purpose of this study is to determine if elevations in oxidative stress, as measured by oxidation-reduction potential (ORP), can distinguish between semen samples from men with abnormal semen parameters from those with normal…
- Trial name
- NCT02839447
- Testing
- Diagnostic
- Where
- 6 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Aytu BioPharma, Inc.
Subfertility, Female
Effect of Sildenafil Citrate Compared to Estrogen as Adjuvant Therapy for Unexplained Infertility
. This study aimed to determine and compare the effect of vaginal sildenafil citrate and estradiol valerate on endometrial thickness, blood flow and pregnancy rates in infertile women.
- Trial name
- NCT05753098
- Testing
- estrogen therapy, Sildenafil, Clomiphene Citrate 50mg
- Where
- Egypt
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Presbyopia
Evaluation of Safety and Efficacy of Intrastromal Implantation of CorVision® Bioengineered Corneal Inlay for Correction of Presbyopia.
This clinical investigation is a prospective, multicentre, non-comparative case series to assess safety and efficacy of CorVision® bioengineered corneal inlay for improving uncorrected near vision in presbyopic subjects.
- Trial name
- CorVision (NCT04465409)
- Testing
- Intrastromal implantation of CorVision bioengineered corneal inlay for correction of presbyopia.
- Where
- Czechia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- LinkoCare Life Sciences AB
Infertility, Male
Male Reproduction COVID Sequelae Study (MARCOS).
The purpose of this study is to investigate the effects of COVID-19 Vaccination on semen parameters and to determine how long these possible changes may last following vaccination.
- Trial name
- NCT04665258
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Infertility Unexplained, IVF
BPA Levels Relationship With IVF/ICSI Outcomes in Unexplained Infertility
The relationship between BPA elevation in urine, blood, and follicle fluid and embryo quality, IVF/ICSI outcomes.
- Conditions
- Infertility Unexplained, IVF, Infertility, Female
- Trial name
- NCT04472234
- Testing
- BPA levels
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Nefise Nazlı YENIGUL
Male Infertility
Validation of New Devices Against Ambient Electromagnetic Radiation
Project Summary Cell phones have become indispensable devices in the investigator's daily life. These phones operate between 400 and 2000 MHz frequency bands and emit radiofrequency electromagnetic waves (EMW).
- Trial name
- NCT04541459
- Testing
- new device against ambient electromagnetic radiation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Waveguard GmbH
Male Infertility
Vitamin E and Male Infertility
The goal of this study is to determine whether there is a correlation between the levels of Vitamin E in sperm and sperm DNA fragmentation.
- Trial name
- NCT00178516
- Testing
- behavior, procedure
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Infertility
Pregnancy/Implantation Rates Using a Day 3 Score Versus Graduated Embryo Score Plus a Biochemical Marker (sHLA-G)
Objective: To compare pregnancy rates and implantation rates when embryos are selected based on a single Day 3 (D.3) score vs. a GES score plus sHLA-G expression.
- Trial name
- NCT00680238
- Testing
- Human derived FSH
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Stellenbosch
Infertility
A Comparison of Two Freezing Techniques
The purpose of this study is to determine the best way to freeze eggs in order to preserve the fertility potential of young women.
- Trial name
- NCT00852306
- Testing
- oocyte freezing
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Infertility
Evaluation of the Impact of Reduced Oxygen Concentration on Embryonic Development
During this study, patients will undergo a routine in vitro fertilization cycle as they would otherwise if not participating in the study.
- Trial name
- LO2 (NCT02919384)
- Testing
- 2% oxygen concentration in the incubator
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Unexplained Infertility
Role of Routine Hysteroscopy in Management of Cases of Unexplained Infertility
The aim of this work is to assess the value of hysteroscopy in unexplained infertility.
- Trial name
- NCT03380364
- Testing
- hystroscope
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Infection Secondary to Surgical Procedure
Antimicrobial Efficacy of ALT005 Ophthalmic Prep Solution in Healthy Volunteers
This is an open-label, randomized, single-dose, placebo-controlled efficacy study to assess the antimicrobial efficacy of ALT005 ophthalmic prep solution following dermal administration in healthy volunteers.
- Trial name
- NCT01531699
- Testing
- ALT005 Ophthalmic Prep Solution, saline control, Betadine ophthalmic prep solution
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Altacor Ltd.
Infertility, Female
Effects of Pentoxifylline and Vitamin E on Pregnancy Rate in Infertile Women Treated by ICSI:
Our findings will provide preliminary clinical evidence to suggest the new experimental treatment approaches, toward female factor infertility treatment with pentoxyfylline.
- Trial name
- NCT03476564
- Testing
- pentoxifylline, Vit E
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Benha University
Infertility, Chromosome Abnormality
Embryo Selection by Noninvasive Preimplantation Genetic Test
The objective of this study is to explore whether non-invasive chromosome screening (NICS) can be used as an effective indicator for embryos selection besides morphology through a multicenter randomized controlled trial, by…
- Trial name
- ESNi-PGT (NCT04339166)
- Testing
- Non-invasive chromosome screening（NICS）
- Where
- 13 sites in China
- Volunteers
- 1,152 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Infertility, IVF
Sex Selection of Human Spermatozoa
This study aims to demonstrate a reliable method of selecting gender specific sperm. X-bearing spermatozoa and Y-bearing spermatozoa will be identified from the density gradient layers.
- Trial name
- NCT05500573
- Testing
- Sperm Sorting
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infertility
Effect of Metformin on Non PCO Women Undergoing IVF/ICSI
400 Patients will be randomly assigned into two groups after informed consent from every patient. They will be classified into 2 groups: Group A ( involves 200 patients ) will receive metformin 850 mg twice daily along the cycle…
- Trial name
- NCT04489147
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
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