Clinical trials: Inflamed Gums
Plaque Induced Gingivitis, Toothbrushing
Clinical ,Microbiological and Compliance Outcomes of AI-based Toothbrushes in Plaque Induced Gingivitis
Severe periodontitis is widespread and begins with reversible gingivitis, driven by poor oral hygiene and a dysbiotic microbiome. Daily toothbrushing is the simplest prevention, but patients still leave plaque.
- Conditions
- Plaque Induced Gingivitis, Toothbrushing, Compliance
- Trial name
- NCT07308522
- Testing
- AI toothbrush, Manual toothbrush, Electric toothbrush
- Where
- Iraq
- Volunteers
- 33 people
- Sponsor
- University of Baghdad
Periodontitis, Gingivitis
Intraoral Scanners as Periodontal and Dental Pathologies Diagnosis Tools
Periodontal diseases and dental pathologies are highly prevalent oral diseases. Thirty-three to fifty percent of adult population presented at least one untreated caries and more than 50% of French population are affected by…
- Conditions
- Periodontitis, Gingivitis, Dental Caries, Diagnosis
- Trial name
- Odonto3D (NCT06006429)
- Testing
- Numerical dental impression by intraoral scanner
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Plaque Induced Gingivitis
Comparison of Saliva Characteristics and Oral Health in Pregnant and Non-pregnant Women
This study compares saliva characteristics and oral health status between pregnant and non-pregnant women. It evaluates salivary pH, buffering capacity, stimulated and unstimulated saliva flow rates, and oral health indicators…
- Trial name
- PREG_ORAL (NCT07896694)
- Testing
- saliva analysis and oral health Assessment, Saliva assessment using the GC Saliva-Check Buffer kit to measure salivary pH and buffering capacity, alongside stimulated and unstimulated salivary flow rate measurements.
- Where
- Iraq
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Kurdistan Higher Council of Medical Specialties
Periodontis, Aggressive Periodontitis
Single-cell and Spatial Transcriptomic Profiling of Gingival Tissues in Aggressive and Chronic Periodontitis: Deciphering Cellular Heterogeneity and Inflammatory Microenvironment Features
The goal of this observational study is to investigate cellular heterogeneity and inflammatory microenvironment features in gingival tissues from patients with aggressive periodontitis compared to chronic periodontitis and…
- Trial name
- NCT07487272
- Where
- China
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Gingivitis
Efficacy of Cuminum Cyminum Herbal =Preparation in Inhibition of Plaque and Gingivitis.
Present work was to investigate the possible efficacy of 0.2% cuminum cyminum herbal preparation as an antiplaque and antigingivitis agent when compared with chlorhexidine.
- Trial name
- NCT04767269
- Testing
- Cuminum Cyminum, herbal Mouthwash
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Gingivitis
Comparative Efficacy of a Toothpaste That Reduces Plaque and Gingivitis
The objective of this study is to evaluate the performance of two toothpastes in controlling established gingivitis and dental plaque in adults.
- Trial name
- NCT00926328
- Testing
- Triclosan, fluoride, Fluoride
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Wound Healing, Palatal Wound
The Effectiveness of Nano Bio Fusion Gingival Gel (NBF) on Wound Healing at the Palate (Donor Site) After Soft Tissue Graft Surgery Compared to Placebo Gel.
The goal of this clinical trial is to assess the effect of Nano-biofusion gingival gel (NBF) on wound healing at the palatal donor site following soft tissue graft surgery and compare it to placebo gel.
- Conditions
- Wound Healing, Palatal Wound, Donor Site Complication, Inflammatory Cytokines
- Trial name
- NCT07330154
- Testing
- Application of NBF gel after soft tissue graft surgery
- Where
- Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Inflamed Gums, Dryness Oral
Regular Antibacterial Photodynamic Therapy on Oral Hygiene in the Elderly 24-hour Care
This study aims to determine the effectiveness of the Lumoral device on oral hygiene, inflammatory load, and dryness of mouth in elderly 24-hour care residents.
- Conditions
- Inflamed Gums, Dryness Oral, Plaque
- Trial name
- NCT05720104
- Testing
- Lumoral Treatment, Standard oral hygiene instructions
- Where
- Sweden
- Sponsor
- Koite Health Oy
Electronic Cigarette Use, Plaque Induced Gingivitis
Efficacy of Oral Hygiene Instructions on Proinflammatory Cytokines Among Cigarette Smokers and Individuals Vaping Electronic Cigarettes During Plaque Induced Gingivitis (Clinical Trial)
To evaluate the level of proinflammatory cytokines in individual vaping electronic cigarette in gingivitis patients. Can vaping affects the proinflammatory cytokines level in diseased individuals? Group I: cigarette smoker with…
- Trial name
- NCT06177158
- Testing
- oral hygiene instructions
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Periodontal Diseases, Gingivitis
Randomized Trial of a Gum Health Formulation
The purpose of this study is to evaluate the safety and efficacy of a newly formulated foaming gel product on gingivitis and/or moderate periodontitis when used with or without the GLO Science accelerating device (GLO Device)…
- Conditions
- Periodontal Diseases, Gingivitis, Periodontitis, Halitosis
- Trial name
- NCT03196648
- Testing
- Gingival health formulation in an accelerating device, Gingival health formulation on a toothbrush, OTC fluoride toothpaste
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Glo Science, Inc.
Gingival Inflammation and Bleeding, Dental Plaque
Clinical Efficacy Evaluation of Three Dentifrices
Clinical study to evaluate and compare the efficacy of two baking soda containing dentifrices, containing 20% and 35% baking soda, to a non-baking soda dentifrice for their ability to reduce gingivitis and plaque following…
- Trial name
- NCT03988374
- Testing
- Dentifrices
- Where
- Canada
- Volunteers
- 319 people
- Sponsor
- Church & Dwight Company, Inc.
Gingivitis, Plaque
Measuring Efficacy of an Oral-Irrigator After Three Weeks of Use
The primary objective of this exploratory study is to evaluate the efficacy of an Oral Irrigator in the reduction of gingivitis compared to a negative control over a 3 week period by using the Modified Gingival Index and the…
- Trial name
- NCT04899440
- Testing
- Water Flosser, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Periodontitis
PerioWave Re-Treatment Protocol Compared to Scaling and Root Planing (SRP) and a Single Treatment With PerioWave
This is a pivotal, prospective, randomized, blinded, multicenter study to evaluate two treatments of photodynamic disinfection in adults with chronic periodontal disease.
- Trial name
- NCT00336661
- Testing
- PerioWave
- Where
- 2 sites in China
- Volunteers
- 105 people
- Sponsor
- Ondine Research Laboratories
Pregnancy Gingivitis
Mobile Health on Improving Efficacy of Plaque Control in Antenatal Women With Gingivitis
Oral health education, behavioral therapy and counselling to improve home care in pregnant females along with periodontal therapy can be helpful in treating pregnancy associated gingivitis and pregnancy outcomes
- Trial name
- NCT06997757
- Testing
- Mobile health, Phase I Therapy
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis, Gingivitis
Herbal Pralines - Oral Health
This randomized, double-blinded, placebo-controlled two-arm, parallel group clinical trial is designed to evaluate the impact of the consumption of two herbal pralines containing 200 mg nitrate on clinical signs of gingival…
- Trial name
- NCT06090851
- Testing
- herbal nitrate Pralines with nitrate, herbal nitrate Pralines without nitrate
- Where
- 2 sites in Germany
- Volunteers
- 44 people
- Sponsor
- Wuerzburg University Hospital
Periodontitis
Local Injection of Periodontal Pocket Method for the Treatment of Gingivitis
Preliminary clinical studies have confirmed that injection of freshly prepared HA35 can reduce symptoms and signs of gingivitis or periodontitis. This clinical study is a prospective repeated experiments.
- Trial name
- NCT05812300
- Testing
- Freshly manufactured 35 kDa hyaluronan fragment
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Dove Medical Press Ltd
Gingivitis
A Clinical Study to Assess the Gingivitis Effects of Various Dentifrices
The objective of this learning clinical study is to assess the gingivitis effects of four different dentifrices over a 3-month period.
- Trial name
- NCT06140771
- Testing
- 0.76% Sodium Monofluorophosphate Dentifrice, 1.15% Sodium Monofluorophosphate Dentifrice, 0.454% Stannous Fluoride Dentifrice
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Gingivitis, Dental Health
CHEER Oral Health in Pregnancy Study
Many pregnant people don't get the dental care they need, even though it's safe and important. The CHEER Study offers free dental check-ups, cleanings, and supplies to help participants take care of their teeth and gums during…
- Conditions
- Gingivitis, Dental Health, Pregnancy, Pregnancy Outcomes
- Trial name
- CHEER (NCT07377344)
- Testing
- Enhanced Care, Enhanced Care +
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- University of California, San Francisco
Gingivitis
Assessing Gingivitis and Plaque From a Marketed Toothpaste
The primary objective of this study is to evaluate the effect of two 0.454% stannous fluoride dentifrices on gingivitis relative to a negative control (Colgate® Cavity Protection toothpaste) and the comparative anti-gingivitis…
- Trial name
- NCT07158112
- Testing
- Stannous Fluoride Dentifrice, Test Stannous Fluoride Dentifrice, Sodium monofluorophosphate dentifrice
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Periodontitis, Gingivitis
Signal-Transducing Adaptor Proteins in Periodontal Disease
This study will look at certain proteins in the gums, saliva, and gum fluid of people with healthy gums, gingivitis (mild gum inflammation), or periodontitis (more severe gum disease).
- Trial name
- NCT07751393
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Inonu University