Clinical trials: Inflammation
Autoinflammatory Disease, Autoimmune Diseases
Flemish Joint Effort for Biomarker PRofiling in Inflammatory Systemic Diseases
A multi-centre, prospective study to study cytokine profiles and other potential disease-specific biomarkers in patients with presumed or confirmed diseases of systemic inflammation The goal of this prospective, observational…
- Conditions
- Autoinflammatory Disease, Autoimmune Diseases, Inflammation
- Trial name
- FEBRIS (NCT05670301)
- Testing
- cytokine and lipidomic profiling
- Where
- 7 sites in Belgium
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Periodontal Disease
Artificial Intelligence for Diagnosing Periodontitis and Monitoring Gingival Inflammation
Background and Objective: Periodontitis and gingivitis are highly prevalent oral diseases that require accurate diagnostic classification and continuous gingival health monitoring.
- Trial name
- NCT07629934
- Testing
- AI-driven Periodontal Diagnostic and Monitoring Algorithms
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Cystic Fibrosis, Allergic Bronchopulmonary Aspergillosis
Mechanisms of Immune Tolerance and Inflammation in Patients With Cystic Fibrosis With ABPA
The goal of this study is to identify the immunological factors that influence a patient's response to the presence of the fungus Aspergillus fumigatus (A. fumigatus) in the lungs.
- Trial name
- ABPA (NCT00585364)
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Depression, Bipolar Disorder
Mitochondrial Dysfunction, Inflammation, and White Matter Integrity in Youth With Mood Disorders
This study consists of three separate appointments including a clinical assessment (interview and questionnaires), a blood draw, a social stress test, and a brain MRI.
- Conditions
- Depression, Bipolar Disorder, Bipolar Disorder Not Otherwise Specified, Unspecified Mood Disorder
- Trial name
- NCT02596698
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy Adults
Effect of Orally Delivered Phytochemicals on Aging and Inflammation in the Skin
The objective is to determine, in a small number of participants, the protective effects of UV-induced skin erythema (reddening or "sunburn") following oral administration of sulforaphane, curcumin, or a combination of the two…
- Trial name
- NCT03289832
- Testing
- Crucera-SGS, Meriva 500-SF
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Inflammation
Effects of Adding Chickpeas to the American Diet (Long Term Study)
This prospective study will assess the effects of adding legumes, especially chick peas, to the diet of healthy adults on the commensal bacteria from feces of human subjects and resulting self-reported GI symptoms as well as…
- Trial name
- NCT02375373
- Testing
- Observational Chickpea Diet
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Florida
Insulin Sensitivity, Overweight or Obesity
Pulses Consumption and Its Role in Managing Systemic Inflammation, Insulin Sensitivity and Gut Microbiome in Human
Objective 1: Characterize indices of systemic inflammation and gut microbiota composition and function after chronic (12 weeks) intake of pulses compared to control diet in human OW/OB-IR participants.
- Conditions
- Insulin Sensitivity, Overweight or Obesity, Inflammatory Response
- Trial name
- PS (NCT04267705)
- Testing
- Control, Black bean, Chickpea
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Chronic Inflammation of Appendix
Laparoscopic Versus Open Appendectomy
comparison between laparoscopic and open appendectomy in the management of chronic appendicitis
- Trial name
- NCT04618666
- Testing
- laparoscopic and open surgery intervention
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Overweight and Obesity
Effect of KETOgenic Diet on Metabolism, Inflammation, Nutrition Deficiencies and OXidative Stress in Women With Overweight
In recent times, the prevalence of obesity increases, reaching an epidemic scale. Elevated body weight is a risk factor in the development of several diseases such as diabetes, hypertension and cancer.
- Trial name
- KETO-MINOX (NCT05652972)
- Testing
- Ketogenic diet, Control diet
- Where
- 2 sites in Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Polish Academy of Sciences
Critical Illness, Cardiac Arrest
Swecrit Biobank - Blood Samples From Critically Ill Patients and Healthy Controls
Blood samples are collected and stored in a biobank for later analysis of circulating substances in peripheral blood and genetic variations in patients with severe critical illness and risk of death.
- Conditions
- Critical Illness, Cardiac Arrest, Sepsis, Influenza
- Trial name
- SWECRIT (NCT04974775)
- Testing
- Blood collection, Blood collection, serial sampling
- Where
- 4 sites in Sweden
- Volunteers
- 8,500 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital
Intravenous Drug Abuse, HIV Infections
Reducing Health Problems Associated With Injection Drug Use
The purpose of this study is to develop and test an intervention to reduce bacterial and viral infections among injection drug users.
- Trial name
- NCT01128920
- Testing
- Skin and Needle Hygiene Intervention, No intervention - assessment-only condition
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Northern Colorado
Chronic Kidney Diseases, Overweight and Obesity
Effect a Honey, Spice-blended Baked Good Has on Salivary Inflammation Markers in Adults: a Pilot Study
The purpose of this research is to determine the effect a spiced-infused baked good has on inflammatory biomarkers in adults who are overweight and/or who has chronic kidney disease.
- Trial name
- NCT05055362
- Testing
- Honey Spice Group
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Florida
Medical Knowledge, Clinical Performance
Utility of High-Fidelity Simulation In the Education and Assessment of Residents in the Recognition and Management of the Sepsis Syndrome
The primary objective of the proposed study will be to determine if a multi-modality teaching curriculum utilizing high-fidelity simulation and didactic lecture will result in sustained improvement by internal medicine residents…
- Trial name
- NCT01992120
- Testing
- Debriefing of high-fidelity sepsis simulation scenarios
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Cognition
The Effect of Pistachio-Rich Breakfast Meals on Cognitive Function in Healthy Older Adults
This study aims to investigate the effect of a breakfast meal containing varying serving sizes (doses) of pistachio nuts on cognitive function throughout the course of the day in healthy ageing adults aged 65-80.
- Trial name
- PACVAN (NCT06900452)
- Testing
- 0.5 serving of pistachios, 1 serving of pistachios, 2 servings of pistachios
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Reading
Neoplasms, Leukemia, Lymphocytic, Chronic
Intermittent Fasting and CLL/SLL
What are the investigators trying to do? By most measures, humans consume more food than needed. Over several decades, overconsumption has led to an increase in a number of diseases, including cancer.
- Conditions
- Neoplasms, Leukemia, Lymphocytic, Chronic, Lymphoma, Small Lymphocytic, Intermittent Fasting
- Trial name
- NCT04626843
- Testing
- Intermittent fast
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eleah Stringer
Inflammation, Insulin Sensitivity
Exercise and Inflammation in the Elderly
Persistent low-grade inflammation and impaired fibrinolysis, are independent predictors of several chronic diseases highly prevalent in the older Veteran population including cardiovascular disease (CVD), stroke, and diabetes.
- Trial name
- IRIS (NCT00753363)
- Testing
- Weight Loss, Aerobic Exercise Training
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Inflammation
Bioequivalency Study of Meloxicam Tablets Under Fasting Conditions
The objective of this study was the bioequivalence of a Roxane Laboratories' Meloxicam tablets, 15 mg, to Mobic® Tablets, 15 mg (Boehringer Ingelheim) under fasting conditions using a single-dose, randomized, 2-treatment…
- Trial name
- NCT00618163
- Testing
- Meloxicam
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Roxane Laboratories
Inflammation, Oxidative Stress
Reduction of Exposure, Inflammation, and Oxidative Stress Following at Least 2 Years of Switching to THS Use Compared to Cigarette Smoking
This is a cross-sectional 3-group study with subjects enrolled and matched by region (Asia, Europe), age, sex, and average daily product consumption over the last 2 years as self-reported.
- Conditions
- Inflammation, Oxidative Stress, Smoking, Smoking Abstinence
- Trial name
- NCT05385055
- Testing
- THS use, Cigarette smoking, Smoking abstinence
- Where
- 37 sites in Bulgaria, Czechia and 4 more
- Volunteers
- 974 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Gastrointestinal Health
Establishing Effects of Bacillus Clausii Probiotic Consumption on Gastrointestinal Health and Inflammation
The study is a randomized, double-blind, crossover, placebo-controlled clinical intervention trial to test the effects of a commercial Bacillus (Shouchella) clausii probiotic compared to a placebo on gastrointestinal symptoms.
- Trial name
- MUNISPORE (NCT07618026)
- Testing
- Bacillus (Shouchella) clausii CSI08
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Risk Factors Cardiovascular Disease, Inflammation
Effects of Exercise With or Without Blueberries on Cardiovascular Risk Markers
About 32 healthy subjects are subjected to 4 weeks of exercise, 4 weeks of washout and 4 weeks of sedentary life style, randomization decides whether they start with exercise or with being "couch potatoes".
- Conditions
- Risk Factors Cardiovascular Disease, Inflammation, Exercise, Sedentary Life
- Trial name
- NCT01274078
- Testing
- Blueberries
- Where
- Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.