Clinical trials: Inflammatory Arthritis
Rheumatoid Arthritis
Evaluation of EULAR-RAID Score in Rheumatoid Arthritis Patients
The Disease Activity Score (DAS) is a system of measurement developed in the 1980s that uses certain criteria, including joint counts and patient perceived disease activity, to measure disease activity in people with Rheumatoid…
- Trial name
- Rainbow (NCT00768053)
- Testing
- Etanercept
- Where
- 17 sites in France, Monaco
- Volunteers
- 108 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Arthritis, Psoriatic
Evaluation of Sonelokimab for the Treatment of Patients With Active Psoriatic Arthritis
This is a study to demonstrate the clinical efficacy and safety of the nanobody® sonelokimab administered subcutaneously (sc) compared with placebo in the treatment of adult participants with active psoriatic arthritis.
- Trial name
- NCT05640245
- Testing
- Sonelokimab, Adalimumab
- Where
- 42 sites in United States, Bulgaria and 6 more
- Volunteers
- 207 people
- Sponsor
- MoonLake Immunotherapeutics AG
Osteoarthritis of the Knee
Efficacy and Safety of the Lidoderm Patch Applied to Patients With Osteoarthritis of the Knee
Patients with knee pain due to Osteoarthritis (OA) experiencing sub-optimal pain relief from their current analgesic regimen will participate in a pilot clinical trial to evaluate the effectiveness and tolerability of the…
- Trial name
- NCT00589979
- Testing
- Lidoderm (Lidocaine 5% Patch)
- Where
- 20 sites in United States
- Volunteers
- 169 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Rheumatoid Arthritis
A Study To Evaluate The Mechanism Of Action Of CP-690,550 In Patients With Rheumatoid Arthritis
To explore the effect of CP-690,550 on blood and synovial markers in subjects with rheumatoid arthritis. To evaluate the safety, tolerability and efficacy of CP-690,550.
- Trial name
- NCT00976599
- Testing
- CP-690,550 + methotrexate
- Where
- 15 sites in United States
- Volunteers
- 29 people
- Sponsor
- Pfizer
Anterior Cruciate Ligament Rupture
Initial Graft Tension and ACL Surgery
The anterior cruciate ligament (ACL) is one of four strong ligaments connecting the bones of the knee joint. If overstretched, the ACL can tear. Reconstruction of a torn ACL is now a common surgical procedure.
- Trial name
- NCT00434837
- Testing
- Initial graft tension during ACL reconstruction surgery
- Where
- 2 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Psoriatic Arthritis
A Study to Evaluate the Efficacy and Safety of PF-06700841 in Subjects With Active Psoriatic Arthritis
This is a 52 week Phase 2b study designed to evaluate the efficacy at 16 weeks and to evaluate the safety and efficacy up to 1 year in subjects with active psoriatic arthritis.
- Trial name
- NCT03963401
- Testing
- PF-06700841
- Where
- 48 sites in Australia, Bulgaria and 9 more
- Volunteers
- 219 people
- Sponsor
- Pfizer
Rheumatoid Arthritis
Evaluation of the Efficacy and Safety of Two Dosing Regimens of Olokizumab (OKZ), Compared to Placebo and Adalimumab, in Subjects With Rheumatoid Arthritis (RA) Who Are Taking Methotrexate But Have Active Disease
The purpose of this study was to determine how effective and safe the study drug Olokizumab was in patients with Rheumatoid Arthritis (RA) who had been already receiving but not fully responding to treatment with methotrexate…
- Trial name
- CREDO 2 (NCT02760407)
- Testing
- Olokizumab 64mg q4w, Olokizumab 64mg q2w, Adalimumab 40mg q2w
- Where
- 203 sites in United States, Argentina and 16 more
- Volunteers
- 1,648 people
- Sponsor
- R-Pharm International, LLC
Psoriatic Arthritis
GOLimumab and Methotrexate Versus Methotrexate in Very Early PsA
An investigator-initiated double-blind, parallel-group randomised controlled trial of Methotrexate versus GOLimumab and Methotrexate in very early PsA using clinical and whole body MRI outcomes.
- Trial name
- GOLMePsA (NCT04108468)
- Testing
- Methotrexate, Golimumab
- Where
- United Kingdom
- Volunteers
- 84 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Gout
To Evaluate the Influence of (LUA Probiotics) on Uric Acid
This study aims to investigate the efficacy of the lactic acid bacteria "LUA probiotics" in reducing serum uric acid levels. The use of health supplements prior to the onset of gout symptoms is proposed as a preventive strategy…
- Trial name
- NCT06969469
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Grape King Bio Ltd.
Arthropathy of Knee
Scorpio® Cruciate Retaining (CR) Outcomes Study
The purpose of this study is to evaluate the design and functional performance of the Scorpio® Cruciate Retaining (CR) Total Knee System.
- Trial name
- NCT00965146
- Testing
- Scorpio® CR Total Knee System
- Where
- 5 sites in United States
- Volunteers
- 215 people
- Sponsor
- Stryker Orthopaedics
Osteoarthritis, Insomnia
Insomnia and Osteoarthritis Study
This research is being done to evaluate the effects of a sleeping pill (eszopiclone, Lunesta)in patients with arthritis of the knee who also suffer from chronic insomnia.
- Trial name
- NCT00374556
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Juvenile Idiopathic Arthritis
Pharmacokinetics Of CP-690,550 In Pediatric Patients With Juvenile Idiopathic Arthritis (JIA)
Phase 1 study to describe pharmacokinetics of CP-690,550 in pediatric patients 2 to less than 18 years of age with Juvenile Idiopathic Rheumatoid Arthritis (JIA).
- Trial name
- NCT01513902
- Testing
- CP-690,550
- Where
- 10 sites in United States, Germany and 2 more
- Volunteers
- 26 people
- Sponsor
- Pfizer
Moderate-to-severe Rheumatoid Arthritis
Real Life Evaluation of Rheumatoid Arthritis in Canadians Taking HUMIRA
The purpose of this study is to evaluate the clinical effectiveness and safety of adalimumab as used in routine clinical practice in adult participants with moderate to severe rheumatoid arthritis (RA) in Canada.
- Trial name
- REACH (NCT01117480)
- Volunteers
- 1,013 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Ankle Osteoarthritis
Evaluating Intra-articular Injection of Axolotl Ambient Compared to Saline in Subjects With Ankle Osteoarthritis
A Double-blind, Multi-Center, Prospective, Randomized Placebo-controlled Pilot Study Evaluating Intra-articular Injection of Axolotl Ambient Compared to Saline in Subjects with Ankle Osteoarthritis.
- Trial name
- Phoenix (NCT05092646)
- Testing
- Axolotl Ambient
- Where
- 3 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Axolotl Biologix
Rheumatoid Arthritis
Atacicept in Combination With Rituximab in Subjects With Rheumatoid Arthritis (August III)
The primary objective of this study is to assess the safety and tolerability of combined treatment with atacicept and rituximab in subjects with active rheumatoid arthritis (RA) receiving re-treatment with rituximab.
- Trial name
- August III (NCT00664521)
- Testing
- Rituximab, Atacicept
- Where
- 8 sites in France, Netherlands and 2 more
- Volunteers
- 27 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Knee Osteoarthritis, Knee Pain Chronic
Molecular Pathways Involved in Knee Pain
Knee osteoarthritis (OA) is the most common form of arthritis and the most common cause of knee pain in the world. The rate of knee arthritis is as high as that of cardiac disease and is the most common problem in individuals…
- Trial name
- NCT04443452
- Testing
- Quantitative Sensory Testing, Radiographic Evaluation, Ultrasound-guided Aspiration
- Where
- United Kingdom
- Volunteers
- 71 people
- Sponsor
- University of Nottingham
Knee Osteoarthritis
Telehealth Exercise and Mindfulness for Pain in Osteoarthritis
This is a parallel-arm mixed-methods randomized controlled trial to investigate the feasibility of telehealth delivered mindful exercise vs. usual exercise interventions for people with knee osteoarthritis.
- Trial name
- TEMPO (NCT05524116)
- Testing
- Mindful Exercise program, Exercise
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University Charles River Campus
Rheumatoid Arthritis
A Long-Term Extension Study of WA22763 and NA25220 of Subcutaneous RoActemra/Actemra (Tocilizumab) in Patients With Moderate to Severe Rheumatoid Arthritis
This multicenter, open-label, single arm, long-term extension study will evaluate the safety and efficacy of RoActemra/Actemra (tocilizumab) in participants with moderate to severe rheumatoid arthritis who have completed the…
- Trial name
- NCT01772316
- Testing
- tocilizumab
- Where
- 12 sites in Spain
- Volunteers
- 47 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
Study Looking at Longitudinal Changes in Fatigue and Health Status in Rheumatoid Arthritis (RA) Patients Treated With Subcutaneous Anti-TNF-α Therapy
People affected by rheumatoid arthritis are often suffering from fatigue and decreased QOL. In this study we are measuring the impact of SC biologics on these parameters.
- Trial name
- NCT01521884
- Testing
- SC anti-TNF
- Where
- Belgium
- Volunteers
- 62 people
- Sponsor
- Pfizer
Osteoarthritis, Knee, Microfragmented Adipose Tissue
Microfragmented Adipose Tissue Versus Platelet-rich Plasma for Knee Osteoarthritis: a Randomized Comparative Trial
The study aims to conduct a randomized trial comparing the clinical outcomes of PRP (standard intervention) versus Microfragmented adipose tissue (investigational) for the treatment of knee osteoarthritis.
- Conditions
- Osteoarthritis, Knee, Microfragmented Adipose Tissue, Platelet-Rich Plasma
- Trial name
- NCT04351087
- Testing
- Platelet Rich Plasma
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Ohio State University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.