Clinical trials: Inflammatory Arthritis, open to volunteers
Osteoarthritis
Effectiveness of Stromal Vascular Fraction (SVF) and Platelet -Rich Plasma (PRP) in Patients With Knee Osteoarthritis: Study Protocol for a Phase III, Prospective, Randomized, Controlled Multi-center Study.
This multicenter, randomized, triple-blind, controlled trial, will enroll 108 patients who will block-randomized in a 1:1 ratio to either the intervention or control group.
- Trial name
- SPOST (NCT05660824)
- Testing
- Stromal Vascular Fraction infiltration, Plattelet Rich Plasma infiltration
- Volunteers
- 108 people
- Sponsor
- Adrien Schwitzguebel
Knee Osteoarthritis (OA), Total Knee Arthroplasty (TKA)
Manual Traction and Rehabilitation After Knee Replacement Surgery
The goal of this clinical trial is to determine whether the addition of manual traction to a standard rehabilitation protocol improves early recovery after primary total knee arthroplasty (TKA) in women aged 50-75 years with knee…
- Trial name
- SMART-TKA (NCT07722559)
- Testing
- Manual Tibiofemoral Traction
- Where
- Kosovo
- Volunteers
- 48 people
- Sponsor
- Alma Mater Europaea - Slovenia
Knee Osteoarthritis
Management of Combined Patellofemoral and Medial Compartment Knee Osteoarthritis
Evaluate the results of management of patients with patellofemoral and medial compartment knee osteoarthritis with open wedge high tibial osteotomy with or without arthroscopic partial lateral patellar facetectomy
- Trial name
- NCT06762171
- Testing
- open wedge high tibial osteotomy, Arthroscopic partial lateral patellar facetectomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Knee Arthritis, Osteoarthritis
Knee Osteoarthritis Rehabilitation Through Rotational Inertia
This study is testing whether a new type of exercise program, called eccentric overload training using a flywheel device, can improve stair-climbing ability in people with knee osteoarthritis.
- Trial name
- KORRI (NCT07424352)
- Testing
- Eccentric resistance training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hip Osteoarthritis, Avascular Necrosis of Femur Head
Influence of Antiseptic Washes on Wound Healing Complications After THA
The purpose of this research trial is to evaluate the effect of two types of washing solutions on wound healing after total hip replacement surgery.
- Trial name
- NCT07104084
- Testing
- lavage chlorhexidine, lavage povidone-iodine
- Where
- 2 sites in United States
- Volunteers
- 420 people
- Sponsor
- F. Johannes Plate
Knee Osteoarthritis
A Multicenter, Postmarket Surveillance Study of Subjects With the Canary canturioTM te Tibial Extension
The objectives of this prospective observational cohort study are to evaluate the safety, reliability, reproducibility, and accuracy of the Canary canturioTM te post-TKA.
- Trial name
- NCT06040827
- Testing
- Total Knee Arthroplasty
- Where
- 7 sites in United States
- Volunteers
- 626 people
- Sponsor
- Canary Medical
Knee Osteoarthritis, Patellofemoral Pain (PFPS)
Assessing the Association Between WBCT PFJ Morphological Metrics and Knee Symptoms
Patellofemoral joint (PFJ) pain is a common, often chronic, aching pain behind or around the kneecap, frequently called "runner's knee".
- Trial name
- NCT07472088
- Testing
- WBCT
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Kansas Medical Center
Axial Spondyloarthritis
Efficacy of Non-invasive Vagus Nerve Stimulation for Axial Spondyloarthritis Resistant to Biotherapies
The primary objective of the study is to study the change in SpA disease activity, according to ASAS20 definition (Anderson et al., 2001), after 8 weeks of VNS treatment versus placebo non-specific stimulation (control group).
- Trial name
- ESNV-SPA (NCT04286373)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Arthritis Osteoarthritis
Comparing Pain Science Education to Biomedical Education for People With Knee Osteoarthritis: A Randomized Controlled Trial
Knee osteoarthritis (OA) is a common cause of pain and disability in older adults. Many people with knee OA believe that pain is primarily caused by joint damage or "wear and tear." These beliefs may contribute to fear of…
- Trial name
- NCT07823673
- Testing
- Pain Science Education, Biomedical Education
- Volunteers
- 82 people
- Sponsor
- McMaster University
Still Disease, Still's Disease, Adult-Onset
Acostill ( RaDiCo Cohort) (RaDiCo Acostill)
Adult Onset Still Disease (AOSD) and Systemic onset Juvenile Idiopathic Arthritis (SoJIA) are two rare multifactorial diseases associated with systemic inflammation.
- Conditions
- Still Disease, Still's Disease, Adult-Onset, Still Disease, Juvenile Onset
- Trial name
- Acostill (NCT05927454)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Knee Osteoarthritis
Neurofeedback for Pain Sensitization in Knee Osteoarthritis
The goal of this clinical trial is to learn whether a training method called neurofeedback is safe and practical to use in people with knee osteoarthritis (knee OA).
- Trial name
- NCT07832682
- Testing
- FWR Down-Conditioning Neurofeedback
- Volunteers
- 50 people
- Sponsor
- Northeastern University
Psoriasis
Multi-Center PAMPA Study
This is a multi-center (North-America), randomized, double-blind, placebo-controlled, wait-list, interventional, preventive trial of guselkumab in high-risk psoriasis patients compared to non-biologic standard of care.
- Trial name
- PAMPA (NCT05004727)
- Testing
- Guselkumab
- Where
- 5 sites in United States, Canada
- Volunteers
- 176 people
- Sponsor
- NYU Langone Health
Systemic Lupus Erthematosus, Systemic Sclerosis (SSc)
Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases
Autoimmune diseases refer to a common category of diseases caused by the immune system reacting to self-antigens, leading to tissue damage.
- Conditions
- Systemic Lupus Erthematosus, Systemic Sclerosis (SSc), Sjogren Syndrome, ANCA Associated Vasculitis (AAV)
- Trial name
- NCT06828042
- Testing
- anti-CD19 CAR T cell therapy
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Peking University Third Hospital
Juvenile Idiopathic Arthritis
Sarcopenia and Juvenile Idiopathic Arthritis
Juvenile idiopathic arthritis (JIA) is a rare chronic inflammatory rheumatic disease that begins during childhood and may persist into adulthood in many patients.
- Trial name
- SAJI (NCT07634354)
- Testing
- Sarcopenia screening assessment
- Where
- France
- Volunteers
- 200 people
- Sponsor
- CHU de Reims
Rheumatoid Arthritis (RA), Remote Patient Monitoring
BloodTrackR Usability and Concordance Study (BUCS): Evaluating a Smart Home-Based Blood Collection Platform for Remote Monitoring in Rheumatoid Arthritis
The BloodTrackR Usability and Concordance Study (BUCS) is evaluating a novel home-based blood collection device and companion mobile application for people with rheumatoid arthritis.
- Trial name
- BUCS (NCT07660029)
- Testing
- BloodTrackR - Home Blood Collection Platform
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Ulster
Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention
Efficacy and Safety of Resveratrol in Patients With Rheumatoid Arthritis.
The aim of the current study is to evaluate the effects of resveratrol on the clinical outcome(s) of patients with moderate rheumatoid arthritis. Objectives : 1.
- Conditions
- Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention, Inflamation, Antioxidant
- Trial name
- NCT07089381
- Testing
- Resveratrol 1 gm., Methotrexate
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Ain Shams University
Infiltration, Shoulder Osteoarthritis
Comparison of the Analgesic Effect of 2 Shoulder Infiltrations
For patients suffering of osteoarthritis, only analgesic treatments such as anti-inflammatory drugs and cortisone infiltrations provide significant but temporary relief of their pain.
- Trial name
- NCT05408065
- Testing
- Triamcinolone Hexacetonide and hyaluronic acid, Triamcinolone Hexacetonide
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Autoimmune Diseases, Autoinflammatory Diseases
Observational Study of Pediatric Rheumatic and Immunologic Diseases in China: The CAPRID Registry
An observational, multi-center, longitudinal registry study for Chinese pediatric patients with rheumatic and immunologic diseases.
- Trial name
- NCT06417502
- Where
- 9 sites in China
- Volunteers
- 20,000 people
- Sponsor
- Peking Union Medical College Hospital
Ankylosing Spondylitis, AS
Expression of Tim-3 on Neutrophils in Ankylosing Spondylitis
1. To investigate the expression of Tim-3 on neutrophils in ankylosing spondylitis patients and its correlation with disease activity and inflammatory markers. 2.
- Conditions
- Ankylosing Spondylitis, AS, Tim3
- Trial name
- NCT07383805
- Where
- Egypt
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Assiut University
Osteoarthritis, Knee
Clinical Efficacy and Safety of Robot-assisted Total Knee Arthroplasty
The purpose of this clinical trial is to understand the application value of the Orthopedic Joint Surgery Navigation System in assisting surgeons to accurately place prosthetic components in adult knee replacement surgery.
- Trial name
- NCT06856356
- Testing
- Robot-assisted surgery, Conventional total knee arthroplasty
- Where
- China
- Volunteers
- 40 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
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