Clinical trials: Inflammatory Disease Activity
Inflammation, Death, Sudden, Cardiac
The Effects of Enzymes and Flavonoids on Inflammation and Coagulation After Marathon
The aim of the present study is to investigate changes in inflammatory status and incidence of infection after extreme aerobic physical stress (participation in a marathon).
- Conditions
- Inflammation, Death, Sudden, Cardiac, Death, Heart Diseases
- Trial name
- Enzy-MagIC (NCT01916408)
- Testing
- Wobenzym plus, PL 1
- Where
- Germany
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Ulcerative Colitis, Crohn Disease
Influence of Aerobic Exercise Training (AET) on Inflammatory Bowel Disease (IBD) in Children and Adolescents
The purpose of this study is to determine if aerobic exercise training can serve as comprehensive palliative care, whereby enhancing cardiovascular fitness, mitigating depressive symptoms and augmenting sleep while bolstering…
- Conditions
- Ulcerative Colitis, Crohn Disease, Depression, Sleep
- Trial name
- Ex-CED (NCT02264275)
- Testing
- Aerobic Exercise Training
- Where
- 3 sites in Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Basel
Prehypertension, Blood Pressure
The Effects of a Jump Rope Exercise Program on Vascular Health, Inflammatory Markers in Prehypertensive Adolescent Girls
The purpose of this study was to examine the impact of a 12-week jump rope exercise program on blood pressure, arterial stiffness, vasodilating and vasoconstricting factors, inflammatory markers, and body composition in…
- Conditions
- Prehypertension, Blood Pressure, Abdominal Obesity, Adiposity
- Trial name
- NCT03534427
- Testing
- Jump rope exercise intervention
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pusan National University
Cardiovascular Diseases
Effectiveness of Sacha Inchi Supplementation on Postprandial Inflammation
The postprandial state increases triglyceride-rich lipoproteins and lipopolysaccharide (LPS) levels, promoting cellular lipids accumulation, insulin resistance, increased inflammatory markers and the formation of foam cells, a…
- Trial name
- ESISOPI (NCT02886169)
- Testing
- High fat meal with Sacha Inchi, high saturated fat meal
- Where
- Colombia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad Icesi
Lung Injury, Acute, Symptoms and Signs
Pulmonary and Inflammatory Responses Following Exposure to a Low Concentration of Ozone or Clean Air
Purpose: The primary purpose of this study is to measure pulmonary function, symptoms, and pulmonary inflammatory responses in healthy young adults during and immediately after exposure to a low concentration of ozone (0.070 ppm)…
- Conditions
- Lung Injury, Acute, Symptoms and Signs, Neutrophilia Acute
- Trial name
- LOCONOZ2 (NCT05680831)
- Testing
- 0.070 ppm ozone concentration, Clean air (0.0 ppm ozone)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Martin W. Case
Inflammatory Bowel Diseases
Study on Lipid Profile Changes in Plasma and Intestinal Mucosa of Patients With Inflammatory Bowel Disease
This study aimed to demonstrate the characteristic lipid profile changes in patients with inflammatory bowel disease.
- Trial name
- NCT06680076
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Psoriatic Arthritis, Arthritis
99mTc-anti-TNF-alpha Scintigraphy in the Evaluation of Inflammatory Processes Activity
Rheumatoid and psoriatic arthritis patients benefit from anti-TNF-α therapy, once it is effective in reducing joint and skin manifestations in 60-70% of patients with inflammatory articular joint and skin diseases.
- Trial name
- NCT02134613
- Testing
- 99mTc-anti-TNF-alpha Scintigraphy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Obstructive Sleep Apnea
The Study of Skeletal Muscle Function in Obstructive Sleep Apnea
The purposes of this study includes (1)to investigate inspiratory muscles and non-inspiratory muscle function in terms of strength, endurance, and fatigability in patients with obstructive sleep apnea (OSA), (2) investigate the…
- Trial name
- NCT00813852
- Testing
- exercise training, IMT
- Where
- Taiwan
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Postpartum Depression, Mood Disorders
Whole-Body Hyperthermia for Mood and Anxiety Disorders
This study aims to examine the scientific mechanisms of whole-body hyperthermia (WBH), a novel, rapidly acting, single session antidepressant and anxiolytic therapy.
- Conditions
- Postpartum Depression, Mood Disorders, Anxiety Disorders, Postpartum Anxiety
- Trial name
- NCT06144294
- Testing
- Whole-Body Hyperthermia, fMRI
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
IBD - Inflammatory Bowel Disease, IBS - Irritable Bowel Syndrome
Low FODMAP Diet on Nutritional Status, Disease Activity and Gut Microbiota in IBS and UC With Normal or Overweight BMI
Gastrointestinal disorders represents 20-50% of referrals to the gastroenterologist; being the most affected womens, youths and older adults.
- Conditions
- IBD - Inflammatory Bowel Disease, IBS - Irritable Bowel Syndrome, UC - Ulcerative Colitis
- Trial name
- NCT04143633
- Testing
- Low FODMAP diet, Standard diet
- Where
- Mexico
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Hospital General de Mexico
Diabetic Ketoacidosis, Heart Disease, Ischemic
Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient
Music intervention is a non-pharmacological and effective intervention that can alleviate anxiety and agitation in patients undergoing weaning.
- Conditions
- Diabetic Ketoacidosis, Heart Disease, Ischemic, Stroke, GastroIntestinal Bleeding
- Trial name
- NCT04977011
- Testing
- relaxing music
- Where
- Taiwan
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Min-Sheng General Hospital
Rheumatoid Arthritis, Spondylitis, Ankylosing
Recombinant Herpes Zoster Vaccine in Patients With Autoimmune Rheumatic Diseases
Introduction: Patients with autoimmune rheumatic diseases (ARDs), rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), psoriatic arthritis (PAs), ankylosing spondylitis (AS), systemic lupus erythematosus (SLE), primary…
- Conditions
- Rheumatoid Arthritis, Spondylitis, Ankylosing, Spondyloarthritis, Systemic Lupus Erythematosus
- Trial name
- RZVRheum (NCT05879419)
- Testing
- Recombinant Herpes Zoster Vaccine (RZV), MTX Discontinuation, MMF Discontinuation
- Where
- Brazil
- Volunteers
- 2,005 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Atopic Dermatitis, Psoriasis
Identification of Cutaneous and Blood Biomarkers Predictive of Response to Systemic Treatments During Chronic Inflammatory Skin Diseases
Chronic inflammatory skin diseases constitute a heterogeneous group of pathologies. They affect the skin but also other organs (joints, lungs, muscles, etc.). Their prognosis and response to treatments is extremely variable.
- Conditions
- Atopic Dermatitis, Psoriasis, Hidradenitis Suppurativa, Lichen Planus
- Trial name
- ImmuneSkinBank (NCT06599411)
- Testing
- Sampling
- Where
- France
- Volunteers
- 830 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Inflammatory Response, Obesity
Exercise and Diet Intervention Attenuated Inflammation Through ASC Gene and Inflammatory Markers in Obese Adults
Background: Obesity is one of the most important health problems worldwide, several factors related to lifestyle as physical inactivity and unbalanced diets increase their development.
- Conditions
- Inflammatory Response, Obesity, Abdominal Obesity, Diet Habit
- Trial name
- INDIEX (NCT04315376)
- Testing
- Exercise-Diet Intervention, Diet Intervention
- Where
- Mexico
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Pro-inflammatory Activity, Immunologic Activity Alteration
Pain, Opioids and Pro-Inflammatory Immune Responses
Providing pain management to the patient who abuses prescription opioids presents a clinical challenge, not only due to concerns about "drug-seeking", but because they have increased sensitivity to pain, a phenomenon identified…
- Trial name
- NCT01210066
- Testing
- Fentanyl, Cold pressor test, Fentanyl plus cold pressor test
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Inflammatory Bowel Diseases (IBD)
Epidemiological Evaluation Of Chronic Kidney Disease In Pediatric Patients With Inflammatory Bowel Disease
This multicenter observational cross-sectional study aims to evaluate the prevalence of chronic kidney disease (CKD) in pediatric patients with inflammatory bowel disease (IBD) and to compare it with a control group without IBD.
- Trial name
- KIBD (NCT07670988)
- Testing
- Clinical and Laboratory Data Collection
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Crohn Disease, Inflammatory Bowel Diseases
Effect of Acupuncture on Patients With Crohn's Disease in Remission
To observe the therapeutic effect of acupuncture on Crohn's disease in remission and its influence of brain functional activity
- Trial name
- NCT04211129
- Testing
- acupuncture
- Where
- 2 sites in China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Ankylosing Spondylitis
Hematological Parameters in Axial Spondyloarthritis
Axial spondyloarthritis is an inflammatory disease characterized by the involvement of the sacroiliac joints and the spine. Disease activity and structural changes are determined by using physical examination, imaging studies…
- Trial name
- NCT05450133
- Testing
- Systemic inflammatory index, BASDAI, ASDAS-ESR
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Bozyaka Training and Research Hospital
Obstructive Sleep Apnea
Weight Loss and Obstructive Sleep Apnea
The purpose of this study is to evaluate the effects of moderate energy restriction on the body adiposity, severity of OSA, blood pressure, sympathetic activity, oxidative stress, inflammatory biomarkers, metabolic profile and…
- Trial name
- NCT02206126
- Testing
- Energy Restriction
- Where
- Brazil
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Disease Activity, Remission of Ulcerative Colitis
Maresin-1 and Resolvin-D1 Levels and Disease Activity in Ulcerative Colitis
Specialized pro-resolving mediators (SPMs), which are typically thought to be formed via consecutive steps of oxidation of polyenoic fatty acids, have been shown to suppress inflammation and promote timely resolution of…
- Conditions
- Disease Activity, Remission of Ulcerative Colitis, Ulcerative Colitis Flare
- Trial name
- NCT06652464
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital