Clinical trials: Inflammatory Status
Type 2 Diabetes Mellitus
Effect of Probiotic Supplementation on Fecal Microbiota, Nutritional Status, Metabolic and Inflammatory Parameters in Patients With Type 2 Diabetes Mellitus
The purpose of this study is to evaluate the effect of probiotic supplementation on fecal microbiota, nutritional status, metabolic and inflammatory parameters in patients with type 2 diabetes mellitus.
- Trial name
- NCT05418179
- Testing
- Probiotic
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Universidade Federal de Santa Catarina
Hypovitaminosis D, Obesity
Hypovitaminosis D and "Metabolic" Inflammatory Status in Patients With Obesity
Since obesity is related to systemic chronic inflammatory status and hypovitaminosis D, the study aimed to assess the incidence of hypovitaminosis D in obese patients and the correlations between vitamin D levels, inflammation…
- Trial name
- ViDO (NCT06115356)
- Testing
- Vitamin D Plasma Level, Bioelectrical Impedance Analysis (BIA) technique, Ferritin
- Where
- Italy
- Volunteers
- 208 people
- Sponsor
- University of Trieste
Obesity, Cardiovascular Diseases
Inflammatory Status of Monocytes in Obesity
The study of the pro-inflammatory activation of circulating monocytes/macrophages in obesity is the main problem of this project.
- Trial name
- NCT05490862
- Testing
- Lifestyle Modification, Traditional Recommendations
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- Federal State Budgetary Scientific Institution
Hashimoto Thyroiditis
Comparison of the Effect of Gluten-Free-Lactose-Free / Aronia Melanocarpa Supplemented Diet in Patients With Hashimoto's Thyroiditis
Hashimoto's thyroiditis (HT) is the most common cause of chronic hypothyroidism in areas with sufficient iodine, stemming from an autoimmune response against thyroid peroxidase and/or thyroglobulin.
- Trial name
- NCT06419309
- Testing
- Dietary intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Halic University
Inflammatory Bowel Diseases
Screening of Nutritional Status and Sarcopenia Among Patients With IBD
1. Screening of malnutrition in patients with IBD and its relation to severity of the disease. 2. Determination of severity of malnutrition in IBD patients. 3. Assessment of Sarcopenia in patients with IBD.
- Trial name
- NCT05877209
- Volunteers
- 100 people
- Sponsor
- Assiut University
Inflammation
Impact of JuicePlus+ on the Health Status of an Overweight Stressed Population
The purpose of this study is to determine if a dried fruit and vegetable supplement (Juice Plus+) can alter the gut microbiome and improve gut permeability and inflammatory levels in an obese, stressed population.
- Trial name
- NCT02512107
- Testing
- Juice Plus+
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Memphis
Crohn's Disease
Efficacy of CROWN in Repair and Maintenance of the Intestinal Mucosa in Patients With CD Receiving Anti-TNF Therapy
The purpose of this study is to evaluate CROWN's efficacy in supporting the repair and maintenance of the intestinal mucosa of patients with moderately to severely active Crohn's Disease receiving anti-Tumor Necrosis Factor (TNF)…
- Trial name
- PIONEER-CD (NCT02793778)
- Testing
- CROWN
- Where
- 39 sites in United States
- Volunteers
- 42 people
- Sponsor
- Prometheus Laboratories
Intervention Studies, ASA Physical Status I
Biological, Radiographic and Clinical Evaluation of Various Inter-Visit Root Canal Dressings in Retreatment Cases
The aim of this clinical trial is to evaluate anti-inflammatory effect of various intracanal medications: 1. Calcium Hydroxide Slurry mixed with 3% Sodium Hypochlorite 2. Calcium Silicate 3.
- Conditions
- Intervention Studies, ASA Physical Status I, Intracanal Medication, Periapical Abscess
- Trial name
- RCT (NCT07641933)
- Testing
- Calcium Silicate Intracanal Medication, Calcium Hydroxide Slurry mixed with Sodium Hypochlorite Intracanal Medication, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
End Stage Renal Disease, Inflammation
Inflammation and Nutritional Parameters in Hemodialysis Patients Using Reprocessed Dialyzers
The study is a prospective cohort trial utilizing sequential laboratory results from excess serum obtained from hemodialysis patients (acting as their own controls).
- Trial name
- NCT00440908
- Where
- 2 sites in United States
- Volunteers
- 2,500 people
- Sponsor
- Fresenius Medical Care North America
Overweight, Obesity
Effect of Reduction of Inflammatory Status on Glucose Metabolism in Overweight Men
Overweight increases the risk to develop chronic diseases including type-2 diabetes and cardiovascular disease. The low-grade inflammatory status often seen in overweight subjects is thought to play an important role in disease…
- Conditions
- Overweight, Obesity, Inflammation
- Trial name
- NCT00221052
- Testing
- Diclofenac
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TNO
Obesity
An Anti-inflammatory Diet Effect on Metabolic, Inflammatory and Immune Status of Obese Younger Adults
Diet has a major role in the etiology of obesity, and there is a growing body of evidence suggesting that a variety of dietary factors can modulate obesity-induced chronic low-grade inflammation and thus the course of…
- Trial name
- NCT03987776
- Testing
- Anti-inflammatory energy-restricted diet, Control energy-restricted diet
- Where
- Croatia
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Center Rijeka
Crohn Disease
Nutritional Status and Body Composition of Adult Patients With Crohn's Disease
Patients with Crohn's disease generally have nutritional risks and malnutrition. The investigators will conduct a multicenter cross-sectional study to discover nutritional status and body composition of Chinese adult patients…
- Trial name
- NCT04915911
- Testing
- cross-sectional study
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Obesity, Inflammation
Transcriptomics of Mononuclear Cells and Inflammatory Status of Obese Patients Treated With Omega-3 Fatty Acids
The main objective is to determine the effect that supplementation with 4.8 g/day of w-3 FA [3.2g eicosapentaenoic acid (EPA) and 1.6 g docosahexaenoic acid (DHA)] have on the inflammatory state of obese patients (BMI ≥ 35.0…
- Conditions
- Obesity, Inflammation, Immune System Disorder
- Trial name
- NCT05219890
- Testing
- Fish oil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Breast Cancer Female
Omega-3 and Vitamin D Supplementation in Breast Cancer Women
Breast cancer (BC) is the most common malignant disease, which is fifth leading cause of cancer mortality worldwide. Poor nutritional status is one of the common physical symptoms found among cancer patients, in which it is…
- Trial name
- NCT05331807
- Testing
- Omega-3 FA, Vitamin D, Combined Omega-3 and Vitamin D Supplementation
- Where
- Palestinian Territories
- Volunteers
- 88 people
- Sponsor
- Universiti Sains Malaysia
Rheumatoid Arthritis
Efficacy of Resistance Exercise and an Anti-Inflammatory Diet on Pain, Disease Activity, Functional Status, and Quality of Life in Patients With Rheumatoid Arthritis
This study aims to examine how resistance exercises and an anti-inflammatory diet affect pain, daily functioning, disease activity, and quality of life in people with rheumatoid arthritis.
- Trial name
- RED-RA (NCT07262112)
- Testing
- Exercise, Diet, Medical management/current medications per standard of care by personal physician.
- Volunteers
- 100 people
- Sponsor
- Berra Yamuç Tanrıöğen
Inflammatory Myopathies
Inspiratory Muscle Training in Patients With Inflammatory Myopathy
Inflammatory myopathies are rare autoimmune diseases leading to progressive muscle weakness, often including the respiratory muscles.
- Trial name
- NCT07274267
- Testing
- Inspiratory Muscle Training (IMT)
- Where
- Poland
- Volunteers
- 33 people
- Sponsor
- Józef Piłsudski University of Physical Education
Parodontitis, Obesity
Inflammatory Status of Visceral Adipose Tissue in Obese Patients Related to Periodontitis Severity
The research aims to compare the inflammatory status of visceral adipose tissue from obese patients depending on the presence and severity of periodontitis, in order to establish a potential causal link between the severity of…
- Conditions
- Parodontitis, Obesity, Metabolism Disorders
- Trial name
- BACTERIOB (NCT02853734)
- Testing
- SEVERE PERIODONTITIS, NO PERIODONTITIS
- Where
- Reunion
- Volunteers
- 122 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Hypovitaminosis D
Cholecalciferol Supplementation for Sepsis in the ICU
Sepsis in a clinical entity that occurs in patients with serious infections. Though the severity of illness may vary, every year, approximately 1.6 million Americans are treated for sepsis.
- Trial name
- CSI (NCT01896544)
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Long COVID
Clinical Trial on a Natural Compound to Improve Chronic Inflammation After SARS-CoV-2 Infection
A controlled, randomized clinical trial is proposed to demonstrate the effectiveness of the experimental product in controlling hepato-pulmonary inflammation and neurovascular encephalic inflammation, which may constitute the…
- Trial name
- NUTRACOVID (NCT07397910)
- Testing
- Experimental Product, Physical exercise, No Physical Exercise
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Healthy Nutrition, Healthy Lifestyle
Fastreset Study: Metabolic Effects of a Five-day Remotely Delivered Hypocaloric and Ketogenic Program
The aim of this study is to assess changes in body and metabolism caused by this new five-day hypocaloric and ketogenic programme
- Trial name
- Fastreset (NCT05821660)
- Testing
- Five-day hypocaloric and ketogenic programme
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Buchinger Wilhelmi Development & Holding GmbH