Clinical trials: Infliximab
Infliximab, Infusion
Infliximab Infusion Rates in Pediatric Inflammatory Bowel Disease
OBJECTIVES OF THE STUDY 1. Investigate whether there are just as few infusion reactions with infliximab infusions of 60 min and 30 min. 2. Investigate patient and nurse satisfaction with infusions of 60 min and 30 min. 3.
- Conditions
- Infliximab, Infusion, IBD (Inflammatory Bowel Disease), Patient Satisfaction
- Trial name
- iRAPID (NCT06839820)
- Testing
- Infusion rate of infliximab
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- University Hospital, Akershus
Crohn Disease, Infliximab
Combined Immunosuppression for Pediatric Crohn's Disease
This is a randomized controlled trial to compare the efficacy and safety of infliximab and immunosuppressives therapy alone or in combination for pediatric Crohn's disease.
- Conditions
- Crohn Disease, Infliximab, Immunosuppression, Children, Only
- Trial name
- NCT05043870
- Testing
- Infliximab and immunosuppressives, Infliximab
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Children's Hospital of Fudan University
IBD, Infliximab
Switching From Intravenous to Subcutaneous Infliximab in Adult Patients With Inflammatory Bowel Disease
The aim of this study is to evaluate the IFX exposure (AUC), effectiveness, presence of ADAbs and treatment burden before and after switching from IV to SC IFX maintenance treatment in a real-world cohort of IBD patients with…
- Conditions
- IBD, Infliximab, Crohn Disease, Ulcerative Colitis
- Trial name
- SHUFFLE (NCT06381518)
- Testing
- Switch to SC CT-P13.
- Where
- Netherlands
- Volunteers
- 38 people
- Sponsor
- Zuyderland Medisch Centrum
Inflammatory Bowel Diseases, Colitis, Ulcerative
Investigation of the Correlation Between Polyamine Levels and Their Key Enzymatic Activities in Association With Inflammatory Bowel Disease Progression
Inflammatory Bowel Disease (IBD), encompassing Ulcerative Colitis (UC) and Crohn's Disease (CD), significantly impairs patients' quality of life.
- Conditions
- Inflammatory Bowel Diseases, Colitis, Ulcerative, Crohn Disease, Polyamines
- Trial name
- NCT06995170
- Where
- China
- Volunteers
- 146 people
- Sponsor
- Xijing Hospital
Crohn Disease, Infliximab
TDM-based Infliximab Treatment for Active Perianal Fistulizing Crohn's Disease
This study will compare the efficacy and safety of TDM (therapeutic drug monitoring)-based infliximab (CT-P13, RemsimaTM) intravenous therapy compared with the standard infliximab (RemsimaTM) intravenous therapy for patients with…
- Conditions
- Crohn Disease, Infliximab, Perianal Fistula Due to Crohn's Disease, Therapeutic Drug Monitoring
- Trial name
- NCT06051253
- Testing
- TDM-based infliximab intravenous therapy, Standard infliximab intravenous therapy
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Asan Medical Center
Ulcerative Colitis, Infliximab
Top Down Versus Step up in Pediatric Ulcerative Colitis
Pediatric Ulcerative Colitis (UC) patients with moderate to severe disease activity at high risk of colectomy. Early use of biologic agents will likely be more effective.
- Conditions
- Ulcerative Colitis, Infliximab, Children
- Trial name
- NCT04999228
- Testing
- Infliximab, Corticosteroids
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Children's Hospital of Fudan University
Crohn Disease, Infliximab
HLADQA1*05 Genotype and the Efficacy of Treatment With Infliximab in Chinese Population Crohn's Disease
Crohn's disease (CD) is a chronic non-specific inflammatory disease of the intestine. Infliximab (IFX) is a kind of one of the anti-tumor necrosis factor agents (anti-TNF) and is the main clinical treatment drug for Crohn's…
- Trial name
- NCT05813860
- Testing
- Azathioprine, Infliximab
- Volunteers
- 976 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Crohn's Disease, Exclusive Enteral Nutrition
Exclusive Enteral Nutrition vs. Infliximab in Chinese CD Patients
prospectively compared Exclusive Enteral Nutrition with Infliximab in the clinical outcomes, mucosal healing, nutrition improvements, adverse effects and gastrointestinal microbiota changes on Chinese Children With active Crohn's…
- Conditions
- Crohn's Disease, Exclusive Enteral Nutrition, Infliximab, Mucosal Healing
- Trial name
- NCT04530877
- Testing
- Infliximab, Exclusive Enteral Nutrition
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Uveitis, Infliximab
A Clinical Trial of Infliximab for Childhood Uveitis
This project is designed to test the hypothesis that infliximab is clinically useful for patients with refractory childhood uveitis.
- Trial name
- NCT04150770
- Testing
- infliximab
- Volunteers
- 10 people
- Sponsor
- Xiaomin Zhang
Rheumatoid Arthritis, Ultrasonography
Ultrasonographic Monitoring of Response to Infliximab in Patients With Rheumatoid Arthritis
To evaluate the predictive value of clinical, functional (HAQ), laboratory and US variables in relation to disease activity and radiographic outcome in patients with RA who start treatment with Remicade at 24 weeks.
- Conditions
- Rheumatoid Arthritis, Ultrasonography, Infliximab
- Trial name
- ULTRA (NCT01282528)
- Testing
- infliximab
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Peking Union Medical College Hospital