Clinical trials: Influenza Prophylaxis
Influenza, Human, Pneumonia
Rapid Assessment of and Prophylaxis for Influenza in Dwellers of Long-term Care Facilities
RAPID-LTCF is a stratified, block-randomized controlled trial to assess the effectiveness of a simple ARI case definition, rapid influenza diagnostic test (RIDT) with wireless transmission of results, and provision of infection…
- Trial name
- Rapid-LTCF (NCT02964871)
- Testing
- Sofia Fluorescent Immunoassay Analyzer Influenza A+B, Usual care
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Coronary Artery Disease
Influenza Vaccination in Prevention From Acute Coronary Events in Coronary Artery Disease - FLUCAD Study
Background: Influenza vaccination is recommended in patients (pts) with cardiovascular disease, however there is a shortage of clinical studies proving its protective effect on clinical course of coronary artery disease (CAD).
- Trial name
- NCT00371098
- Testing
- Influenza vaccination: Influvac (SolvayPharma)
- Where
- Poland
- Volunteers
- 658 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Healthy Participants
Influenza Virus Vaccine Plus Vitamin A and D Supplements for Prevention of Respiratory Virus Infections in Children
Children are particularly vulnerable to respiratory virus infections, especially influenza. Vitamin A \& D deficiencies are associated with vulnerability to infectious diseases of the respiratory tract.
- Trial name
- NCT02649192
- Testing
- Influenza virus vaccine, Vitamins A and D
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
COVID-19
Evaluation of Corfluvec Vaccine for the Prevention of COVID-19 in Healthy Volunteers
The aim of the study is to investigate the safety and immunogenicity of a two-component intranasal vaccine for the prevention of COVID-19 in healthy volunteers 18-60 years old
- Trial name
- NCT05696067
- Testing
- Corfluvec component 1 low dose, Corfluvec component 2 low dose, Corfluvec component 1 high dose
- Where
- 2 sites in Russia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tatyana Zubkova
Acute Respiratory Infection
Meditation and Exercise for Prevention of Acute Respiratory Infection
The overarching goal of this project is to determine whether mind-body practices such as meditation or exercise can reduce the public health burden of acute respiratory infection.
- Trial name
- MEPARI (NCT01057771)
- Testing
- Meditation, Exercise
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Influenza
Evaluation of Alternative Oseltamivir (Tamiflu) Dosing Strategies.
Objective 1: Determine the safety and toxicity profile of Tamiflu administered in combination with probenecid in healthy adults.Objective 2: Determine the pharmacokinetic profile of Tamiflu and probenecid in healthy adults.
- Trial name
- NCT00304434
- Testing
- Oseltamivir, Probenecid
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Influenza
Project to Investigate Ways to Reduce the Spread of Influenza in Schools and Households With Children
The purpose of this study is to understand the spread of influenza (flu) in schools and households with elementary (K-5) school children, and develop ways to reduce the flu using non-pharmaceutical means.
- Trial name
- PIPP (NCT00446628)
- Testing
- behaviors reducing spread of influenza
- Where
- United States
- Volunteers
- 3,360 people, healthy volunteers welcome
- Sponsor
- Kiren Mitruka
Influenza
Hutterite Influenza Prevention Study
The goal of this randomized clinical trial is to determine whether immunizing children in Hutterite colonies with inactivated influenza vaccine can prevent influenza and its complications in other colony members.
- Trial name
- NCT00877396
- Testing
- Influenza vaccination, Hepatitis A Vaccine
- Volunteers
- 4,771 people, healthy volunteers welcome
- Sponsor
- McMaster University
Influenza
The Chloroquine for Influenza Prevention Trial
A randomised controlled trial to determine the efficacy of chloroquine for the prevention of influenza
- Trial name
- CHIP (NCT01078779)
- Testing
- Chloroquine
- Where
- Singapore
- Volunteers
- 1,516 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Childhood Influenza Vaccination, School-located Influenza Vaccination
Evaluation of the School Kids Influenza Prevention Project
Children whose parents receive text reminders are more likely to be consented to participate in the school located influenza vaccination clinic than children whose parents do not receive text reminders.
- Trial name
- SKIPP (NCT03307642)
- Testing
- Text message notification
- Where
- United States
- Volunteers
- 18,540 people
- Sponsor
- University of Rochester
Upper Respiratory Infections, Influenza
Effectiveness of a Handwashing Programme in the Prevention of School Absenteeism Due to Respiratory Infections
The aim of the study was to assess the effectiveness of a hand-washing programme using hand sanitizer in the prevention of school absenteeism due to upper respiratory infections.
- Conditions
- Upper Respiratory Infections, Influenza, Common Cold
- Trial name
- NCT01728090
- Testing
- hand sanitizer
- Volunteers
- 1,640 people
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
Pandemic Influenza, Prevention
Safety and Immunogenicity of an Inactivated Pandemic Influenza Vaccine
A single center, randomized and double-blind phase II clinical trial is to be conducted in adults to evaluate the safety and immunogenicity of an inactivated pandemic influenza vaccine (whole-virion, aluminium-adjuvanted).
- Trial name
- NCT00535665
- Testing
- pandemic influenza vaccine (H5N1 strain NIBRG-14)
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Sinovac Biotech Co., Ltd
Influenza Infection
Catechin Gargling for Influenza Infection
The purpose of this study is to clarify the preventive effects of catechin gargling on the influenza infection.
- Trial name
- NCT00239213
- Testing
- catechin extracts (health food)
- Where
- 3 sites in Japan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Shizuoka
Influenza
Tolerability and Safety Study of FLUVAL P Monovalent Influenza Vaccine in Children
To determine the tolerability and safety of FLUVAL P monovalent influenza vaccine in children.
- Trial name
- NCT01100294
- Testing
- Vaccination with FLUVAL P
- Where
- Hungary
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fluart Innovative Vaccine Ltd, Hungary
Influenza, Human
Prophylactic Treatment With Oseltamivir
The purpose of this study is to compare the efficacy of 5-day versus 10-day oseltamivir prophylactic treatment in patients who had been exposed to influenza.
- Trial name
- NCT03899571
- Testing
- Oseltamivir Oral Capsule for 5 days post-exposure, Oseltamivir Oral Capsule for 10 days post-exposure
- Where
- Slovenia
- Volunteers
- 222 people
- Sponsor
- University Medical Centre Ljubljana
Influenza A Virus Infection
Evaluation of the Safety and Immunogenicity of a Live Attenuated Virus Vaccine for the Prevention of H2N3 Influenza
In recent years, influenza viruses that have traditionally infected animals have infected humans as well. The H2N3 influenza virus, which first appeared in pigs in the Midwest United States in 2006, may pose a potential health…
- Trial name
- NCT01175122
- Testing
- H2N3 MO 2003/AA ca Vaccine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Influenza Prevention
The Safety and Immunogenicity Evaluation of Live Attenuated Influenza Vaccine
Live Attenuated freeze-dried Influenza Vaccine has been licensed for use in 2020 (Approval No.S20200002), the sponsor of this research submitted an new application for non freeze-dried Live Attenuated Influenza Vaccine in 2021.
- Trial name
- NCT05284851
- Testing
- Live Attenuated Influenza Vaccine(non freeze-dried), Live Attenuated Influenza Vaccine(freeze-dried)
- Where
- China
- Volunteers
- 2,520 people, healthy volunteers welcome
- Sponsor
- Changchun BCHT Biotechnology Co.
Influenza A
A Phase 2 Study to Evaluate the Efficacy and Safety of VIR-2482 for the Prevention of Illness Due to Influenza A
The purpose of this study is to evaluate the efficacy, safety, and tolerability of VIR-2482 compared to placebo in preventing influenza A illness in healthy adults 18 to <65 years of age without pre-existing risk factors for…
- Trial name
- NCT05567783
- Testing
- VIR-2482 (450 mg), VIR-2482 (1200 mg)
- Where
- 51 sites in United States
- Volunteers
- 2,977 people, healthy volunteers welcome
- Sponsor
- Vir Biotechnology, Inc.
Aspergillosis; Pulmonary, Invasive (Etiology)
Posaconazole for the Prevention of Influenza-associated Aspergillosis in Critically Ill Patients
The objective of this study is to deliver proof of concept that antifungal prophylaxis can reduce the incidence of Influenza Associated Aspergillosis (IAA) in ICU (intensive care unit) patients with severe influenza.
- Trial name
- POSA-FLU (NCT03378479)
- Testing
- SOC +Posaconazole 18 MG/ML (milligram/milliliter), standard of care (SOC)
- Where
- 12 sites in Belgium, France and 1 more
- Volunteers
- 88 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Influenza Prevention
A Phase 2 Study of a Subcutaneous Injection of TAK-850 in Healthy Adult Participants
This clinical trial is a Phase 2 study of a single subcutaneous injection of TAK-850 for 22 days in healthy Japanese adults.
- Trial name
- NCT02713061
- Testing
- TAK-850
- Where
- Japan
- Volunteers
- healthy volunteers welcome
- Sponsor
- Takeda