Clinical trials: Information Disclosure
Informed Consent, Comprehension
AI-Driven Consent Simplification Study
The overarching goal of this pilot is to explore how generative artificial intelligence (genAI) can be used to improve the accessibility and understandability of informed consent materials in clinical research.
- Conditions
- Informed Consent, Comprehension, Communication, Disclosure
- Trial name
- ACCESS (NCT07303517)
- Testing
- Original ICF, AI Simplified ICF, Podcast - Original ICF
- Where
- United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Mother to Child Transmission, Pregnancy in Adolescence
Digital Intervention to Address Stigma Among Pregnant Adolescents Living With HIV
Pregnant adolescents living with HIV (ALHIV) in Kenya frequently experience stigma and difficulty telling a family member about their HIV and pregnancy status.
- Conditions
- Mother to Child Transmission, Pregnancy in Adolescence, Social Stigma, Self Disclosure
- Trial name
- NCT05383755
- Testing
- Digital intervention for pregnant adolescents living with HIV
- Where
- Kenya
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation
Disclosure Rates of Social Needs
iScreen Study: Best Methods for Social Screening in Pediatric Caregivers
The goal is to better understand the social needs of a population seeking care in a large, urban children's hospital emergency department with a large Medicaid population.
- Trial name
- NCT02197052
- Where
- United States
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Ebola Virus Disease, Marburg Virus Disease
Evaluation of Safety, Tolerability and Immune Responses of Ebola-S and Marburg Vaccines in Healthy Adults
Primary Objective: To evaluate the safety and tolerability of cAd3-EBO-S and cAd3 Marburg vaccines when administered Intramuscular (IM) at a dose of 1 x 10^11 particle units (PU) to healthy adults.
- Trial name
- NCT04723602
- Testing
- cAd3-Marburg, cAd3-EBO-S
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Albert B. Sabin Vaccine Institute
Alzheimer Disease, Dementia
BarcelonaBeta Dementia Prevention Research Clinic: a Study on Risk Factors Disclosure
Alzheimer's disease (AD) is the leading cause of dementia and its prevalence is estimated to exceed 100 million affects by 2050, becoming the main public health problem worldwide.
- Conditions
- Alzheimer Disease, Dementia, Mild Cognitive Impairment, Subjective Cognitive Decline
- Trial name
- NCT03847038
- Testing
- Preventive strategies advice and dementia risk estimate disclosure
- Where
- Spain
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Barcelonabeta Brain Research Center, Pasqual Maragall Foundation
Focus is on Behavior of Health Professionals Generally
The Effect of Remote Treatment on Medical Provider Creative Thinking and Patient Disclosure
The investigators will be doing this study to understand how the environment of communication (including talking about health) impact doctors' ability to find solutions and health issues to clinical problems for patients.
- Trial name
- MED-CREATE (NCT06784635)
- Testing
- In person, Online interaction
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Ayoub Bouguettaya
Mental Health Issue
A Study Protocol on Peer Digital Acceset (PDA)
This protocol delineates a randomized controlled trial for evaluating the implementation and clinical effectiveness of Assecet, a digital peer support intervention for youth mental well-being, which comprises two components.
- Trial name
- PDA (NCT05083676)
- Testing
- Acceset Intervention
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The N.1 Institute for Health (N.1)
Hiv
Exploring a Digital HIV Onward Disclosure Intervention, in People Living With HIV of Sub-Saharan African Ethnicity.
Research has shown that people living with HIV struggle to disclose their HIV status to others, (a process known as self-disclosure or onward disclosure) due to associated challenges, including fear of discrimination from others.
- Trial name
- NCT05804968
- Testing
- Digital HIV Self Disclosure Intervention
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Royal Holloway University
Trust
Do Patients Perceive Surgeons Who Provide Personal Information as More Trustworthy and Empathetic?
Prior studies have shown that patient trust in their physician is associated with better health outcomes and lower levels of emotional distress.
- Trial name
- NCT04213625
- Testing
- Surgeon Personal Background
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Trauma, Emotions
Experiential Training in Eliciting Disclosure & Emotions for Mental Health Trainees
Many people seek psychotherapy to alleviate symptoms related to trauma and stressful conflicts, and many psychotherapy approaches aim to help people process trauma and conflicts through eliciting client disclosure of these…
- Conditions
- Trauma, Emotions, Disclosure
- Trial name
- NCT04511754
- Testing
- Experiential Psychotherapy Skill Training, Standard Psychotherapy Skill Training
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Mark A. Lumley
Traumatic Stress, Post-Traumatic Growth
To Observe the Psychophysiological Alterations in Traumatic Stress Subjects
This Multicenter study is planned to investigate the effectiveness of the guided disclosure protocol for the promotion of post-traumatic growth (PTG), in the traumatic stress subjects and to determine whether PTG is associated…
- Trial name
- NCT04217863
- Testing
- GDP
- Where
- Pakistan
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- University of Karachi
Healthy
Oxytocin, Trauma Disclosure and Intrusions
Severe traumatic experiences such as falling victim to assault, torture, or rape have deleterious effects. Clinical manifestations include intrusions, avoidance behavior, and hyperarousal, which are associated, at a circuit…
- Trial name
- NCT03425929
- Testing
- Oxytocin
- Where
- Germany
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
HIV Infections, Sexually Transmitted Infections (Not HIV or Hepatitis)
Developing an HIV Disclosure Intervention for Men in Uganda
The goal of this clinical trial is to test an HIV disclosure intervention that the investigators are developing focused on men living with HIV in Uganda.
- Trial name
- DASH (NCT05771519)
- Testing
- HIV disclosure intervention
- Where
- Uganda
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Social Skills, Self-Criticism
Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking
The purpose of this randomized controlled trial is to evaluate an intervention, Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS).
- Conditions
- Social Skills, Self-Criticism, Post-traumatic Stress Disorder, Depression
- Trial name
- NCT03488927
- Testing
- Supporting Survivors and Self: An Intervention for Social Supports of Survivors of Partner Abuse and Sexual Aggression (SSS)
- Where
- United States
- Volunteers
- 1,268 people, healthy volunteers welcome
- Sponsor
- University of New Hampshire
Endodontic Diseases, Clinical Communication
Generative AI-Based Immersive Training for Endodontic Risk Disclosure and Informed Consent Among Dental Students
The objective of this prospective, parallel-group, 1:1 randomized controlled trial is to evaluate the effectiveness of a generative artificial intelligence (AI)-based immersive training program, utilizing the Gemini platform, in…
- Conditions
- Endodontic Diseases, Clinical Communication, Informed Consent
- Trial name
- GAI-ENDORDIC (NCT07731867)
- Testing
- Generative AI-Based Immersive Training, Conventional Case-Based Learning
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
Patient Doctor Trust
Disclosure of Industry Payments to Physicians and the Patient-Doctor Relationship
Pharmaceutical and medical device manufacturers work closely with doctors and hospitals, and the companies often pay large sums for consulting and advising services.
- Trial name
- NCT02179632
- Testing
- Exposure to disclosure website
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Lewy Body Disease
Alpha-synuclein Education and Disclosure in Individuals With Preclinical and Symptomatic Lewy Body Disease
The goal of the study is to assess if learning one's Lewy Body Dementia (LBD) biomarker test result impacts longitudinal psychosocial and behavioral responses and to identify factors that moderate and mediate these outcomes.
- Trial name
- NCT07646652
- Testing
- LBD Biomarker Education and Disclosure
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Stanford University
Mental Illness, Behavior Disorders
Up To Me: Erasing the Stigma of Mental Illness on College Campuses
This is a three-lesson, disclosure-based stigma reduction program meant to reduce barriers to community living and participation for college students with psychiatric disabilities.
- Conditions
- Mental Illness, Behavior Disorders, Severe Mental Illness, Psychiatric Diagnosis
- Trial name
- NCT05784818
- Testing
- Up To Me Intervention + No Booster, Up To Me Intervention + Booster
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Education
Transition From Research to Disclosure in Human Genetics
The goal of this study is to design a means of providing research families, from diverse geographical locations, the chance to receive genetic testing after having been educated by video, and meetings or telephone conversations…
- Trial name
- NCT00505466
- Testing
- Genetic Counseling
- Where
- United States
- Volunteers
- 577 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cardiovascular Diseases
Loneliness and Social Connection in Cardiovascular Disease
The study evaluates the impact of vulnerable self-disclosure and perceived responsiveness in individuals across levels of loneliness. Participants will be randomized to a high disclosure or a low disclosure condition.
- Trial name
- NCT04195620
- Testing
- High self-disclosure, Low self-disclosure
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Morehead State University