Clinical trials: Inhalation
Adrenal Insufficiency
The Treatment of Adrenal Crisis With Inhaled Prednisolone
Rationale: An adrenal crisis is an acute life-threatening event which may occur in patients with adrenal insufficiency. The initial emergency treatment consists of an intramuscular injection with 100 mg hydrocortisone…
- Trial name
- TRACER (NCT05639127)
- Testing
- Prednisolone
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Respiratory Function, Runners
The Effects of a Mindfulness Program on Running Performance, Respiratory Function, and Heart Rate Variability
Broadly, the objective of the research is to evaluate the effectiveness of a specific breathwork program (Les Mills Breath) on various physiological variables related to running performance, compared to a mindfulness control (20…
- Trial name
- NCT07521956
- Testing
- Mindful meditation, Breathwork
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Fraser Valley
Physiological Adaptations, Sport Performance
Molecular Hydrogen Inhalation: Effects on Health, Exercise Capacity and Inflammatory Response - in Vivo/in Vitro Studies
Summary To comprehensively address the research aims and explore the state of knowledge of the mechanisms of biochemical response to specific tissue affecting method in form of a molecular hydrogen inhalation and will allow to…
- Conditions
- Physiological Adaptations, Sport Performance, Aerobic Capacity, Anaerobic Power
- Trial name
- NCT07130942
- Testing
- Inhalation using a molecular hydrogen generator
- Where
- Poland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Health Behavior, Quality of Life
Yoga Effects on Heart Rate Variability and Electroencephalography
Since yoga breathing exercises are traditionally used to tranquilize the mind, and have a well-known positive effect on the cardiovascular system, it is our hypothesis that a respiratory yoga exercise named bhastrika pranayama…
- Trial name
- NCT01866683
- Testing
- 1 month respiratory training, 1 month waiting period
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Swimming, Inspiratory Muscle Strength
Effects of Inspiratory Training on Respiratory Function in Swimming
Introduction: The diaphragm is the primary inspiratory muscle and plays a key role in ventilation, trunk stability, and exercise efficiency.
- Conditions
- Swimming, Inspiratory Muscle Strength, Inspiratory Muscle Training
- Trial name
- NCT07595341
- Testing
- Inspiratory training
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Pregnancy Related, Dyspnea
Effect of Breathing Exercises and Upper Limb Endurance Exercises in Pregnant Women Presented With Physiological Dyspnea
To evaluate the effects of breathing exercises and upper limb endurance exercises in pregnant women presented with physiological dyspnea
- Trial name
- NCT05710003
- Testing
- breathing exercises
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Entsar Hsanen
Respiratory Insufficiency, Ventilation Therapy; Complications
KAP Asynchrony Survey
The investigators developed a web-based survey to assess knowledge, attitudes and practice of health care professionals about patient-ventilator asynchrony.
- Conditions
- Respiratory Insufficiency, Ventilation Therapy; Complications, Ventilators, Mechanical, Respiration, Artificial
- Trial name
- KAPA (NCT03439683)
- Testing
- Survey about patient-ventilator asynchrony
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Ophthalmic, Surgery
Comparison of Desflurane Anesthesia Versus TIVA-TCI in Patients Undergoing Ophthalmic Ambulatory Surgery
This is a single-center, randomized, prospective research which aims to investigate the advantages and disadvantages between desflurane balanced anesthesia and TIVA-TCI with propofol in ophthalmic ambulatory surgery, so that to…
- Conditions
- Ophthalmic, Surgery, Anesthesia
- Trial name
- NCT02922660
- Testing
- desflurane, total intravenous anesthesia, inhalation anesthesia
- Where
- China
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Xiaoliang Gan
Healthy, Caregiver Burden
Effects of Breathing Therapy and Benson Relaxation Technique on Caregivers of Alzheimer's Patients
This randomized controlled trial aims to investigate the effects of respiratory therapy and the Benson Relaxation Technique on caregiver burden, perceived stress, and self-efficacy among caregivers of individuals with Alzheimer's…
- Conditions
- Healthy, Caregiver Burden, Caregiver Stress, Caregiver
- Trial name
- NCT06997523
- Testing
- Breath Therapy and Benson Relaxation Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Hülya Nuray Bayraktar
Weaning Failure
Predictive Value of Airway Occlusion Pressure, Maximal Inspiratory Pressure and Their Ratio for Successful Extubation in Patients With Traumatic Brain Injury
The aim of this study will be to measure the predictive power of the respiratory muscle determinants including The maximal inspiratory pressure, and central drive determinant including Airway occlusion pressure and ratio between…
- Trial name
- NCT06627686
- Testing
- Air way occlusion pressure
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Ostomy
Effects of Sleep Hygiene Education and Lavender Oil Inhalation on Sleep Quality, Fatigue, Quality of Life
Self-care non-pharmacological methods can help reduce the negative health effects of sleep problems or insomnia. This trial aims to investigate the effects of sleep hygiene education and lavender oil inhalation alone and in…
- Trial name
- MU-RKOCA-01 (NCT05573256)
- Testing
- Lavender oil inhalation, Sleep hygiene education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Marmara University
Breathing Pattern Disorder, Breathlessness
The Physiotherapy Assessment of Breathing Pattern Disorder
This study aims to evaluate a clinical tool called the Breathing Pattern Assessment Tool (BPAT), which is used by physiotherapists to assess breathing pattern disorder (BPD).
- Trial name
- PHAB (NCT07543588)
- Testing
- Assessment of Breathing Pattern- Breathing Pattern Assessment Tool
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Blood Pressure, Vascular Function
Smartphone App-guided Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure
This clinical trial aims to assess the efficacy of inspiratory muscle strength training (IMST) guided by a smartphone app vs. IMST delivered in a clinical research setting for lowering systolic blood pressure in adults 18 years…
- Conditions
- Blood Pressure, Vascular Function, Adherence, Treatment
- Trial name
- NCT06229873
- Testing
- App-Based Inspiratory Muscle Strength Training, Clinic-Based Inspiratory Muscle Strength Training
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Cannabis Use, Tobacco
Lung Health and Breath Biomarkers: Acute Effects of Inhaled Cannabis
This outpatient study examines how inhaled cannabis, combustible or vaporized, alters lung health and breath biomarkers compared to a tobacco cigarette.
- Conditions
- Cannabis Use, Tobacco, Biomarkers
- Trial name
- NCT07694466
- Testing
- Cannabis (THC), Tobacco Cigarette
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hannah Harris
Weightlifting, Breathing
The Effects of Cervical and Thoracic Manipulation Therapy Applied to Weightlifting Athletes
The effects of manipulation therapy on the autonomic nervous system have been examined in the literature and while no sympathetic or parasympathetic changes were found after upper thoracic manipulation, a decrease in sympathetic…
- Conditions
- Weightlifting, Breathing, Breath Tests, Athlete
- Trial name
- NCT06606795
- Testing
- Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Yoga
The Effect of Yoga Self-Practice on Sleep Disturbance
The study will examine the effect of Restorative Yoga self-practice on sleep disturbance in the Chinese adult population. Restorative Yoga is a relaxation-focused yoga style which includes a series of static stretching poses and…
- Trial name
- NCT04719039
- Testing
- Restorative Yoga Internvention
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Bronchiectasis
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis
The aim of this clinical trial is to assess the safety of: single doses of the study drug CHF6333 in Healthy Volunteers (HVs) and in subjects with Bronchiectasis (BE) - Part I repeated doses of the study drug CHF6333 in subjects…
- Trial name
- NCT06166056
- Testing
- CHF6333
- Where
- 8 sites in United Kingdom
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Asthma
Effects of Papworth Breathing With or Without Bridge Pose Yoga in Asthma Patients
Asthma is a chronic condition causing airway inflammationandconstriction, leading to symptoms like shortness of breath, wheezing, andchest tightness.
- Trial name
- NCT07440953
- Testing
- Papeworth Breathing, Pap-worth Breathing + Bridge Pose Yoga
- Where
- Pakistan
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cardiac or Respiratory Arrest, Anaesthesia
Head Positions to Open the Airway IV
After routine induction of general anaesthesia peak airway pressure (= P max) and other respiratory parameters(i.e. expiratory tidal volume, expiratory CO2) are measured with and without head support in three different head…
- Trial name
- NCT01909310
- Testing
- head extension, neutral position, anaesthesiologist´s position
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
COPD, IPF
Functional MR Lung Imaging Using Hyperpolarised 129Xe
The aim of this study is to investigate the potential value of a novel imaging technique (hyperpolarized 129Xe lung imaging) in the diagnosis and assessment of lung disease in patients with COPD and IPF.
- Trial name
- NCT02976935
- Testing
- hyperpolarised 129 Xenon
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
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