Clinical trials: Inhalation
COVID-19 Pandemic
A Study of FB2001 for Inhalation in Healthy Chinese Adults
FB2001 is a novel inhalable preparation being developed for COVID-19 treatment. A Double-Blinded, Randomized, and Placebo-Controlled Phase 1 Study to Assess the Safety, Tolerability and Pharmacokinetics Profile of Single and…
- Trial name
- NCT05583812
- Testing
- FB2001 for inhalation
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Frontier Biotechnologies Inc.
Inspiratory Muscle Training, Shooting Performance
Inspiratory Muscle Training Enhances Jumping Power and Shoot-ing Performance in Elite Air Pistol Athletes
This randomized controlled trial investigated the effects of a four-week inspiratory muscle training (IMT) program on physical and motor performance parameters and shooting accuracy in elite male air pistol athletes.
- Conditions
- Inspiratory Muscle Training, Shooting Performance, Jump Performance, Precision Sport Performance
- Trial name
- NCT07406451
- Testing
- Inspiratory Muscle Training (IMT) Group, Control Group (A):
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Gümüşhane Universıty
Healthy Volunteers
Multiple Dose Healthy Volunteer Study of PF-03715455.
Evaluation of the multiple dose pharmacokinetics of PF-3715455 in healthy volunteers
- Trial name
- MD-MULTI DOSE (NCT01186757)
- Testing
- PF-03715455
- Where
- Singapore
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pfizer
Endothelial Dysfunction
Effects of Carbon Monoxide Breathing on Blood Vessel Function
In healthy young adults 18-39 years of age, the investigators will determine if intermittent inhalation a 0.1% CO, from a 1-liter bag once every minute for 30-40 minutes, at a level that approaches the CO boost with hookah…
- Trial name
- NCT03067701
- Testing
- Carbon Monoxide
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Fibromyalgia, Respiratory Alkalosis and Metabolic Acidosis
Evaluation of Respiratory Function in Fibromyalgia
This study will evaluate respiratory function in people with fibromyalgia and whether or not breathing patterns in this patient group can be explained by stress, emotional or biomechanical variables.
- Conditions
- Fibromyalgia, Respiratory Alkalosis and Metabolic Acidosis, Chronic Hyperventilation
- Trial name
- NCT04098731
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Extubation Success, Extubation Failure
Combined RSBI, TOF, and BIS for Prediction of Extubation Success
This prospective observational study aims to evaluate the predictive value of the combined use of the rapid shallow breathing index, train-of-four ratio, and bispectral index for extubation success after general anesthesia.
- Conditions
- Extubation Success, Extubation Failure, Postoperative Respiratory Complications
- Trial name
- NCT07577453
- Testing
- Combined pre-extubation assessment using RSBI, TOF ratio, and BIS
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Child Behavior, Problem Behavior
Clinical Study of Behavior Problems in Children After Different Anesthesia Methods
The aim of this study is to investigate long-lasting or later behavioral changes in children in the context of different anesthesia techniques (Inhalation anesthesia vs. TIVA)
- Trial name
- PST (NCT02945072)
- Testing
- TIVA, Sevoflurane
- Where
- Switzerland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Healthy, Hypercapnia
Study of Brain Blood Flow During Induced Hypercapnia (Excess Blood Carbon Dioxide)
This study will evaluate magnetic resonance imaging (MRI ) methods for measuring changes in the brain's blood flow during hypercapnia (a condition of excess carbon dioxide in the blood).
- Trial name
- NCT00001845
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Respiratory Muscles, Breathing Exercises
Respiratory Muscles and Inspiratory Muscle Training
The effects of inspiratory muscle training (IMT) remain controversial. Many studies have examined the effect IMT has on exercise performance, but any changes to the body that come from IMT have yet to be looked at.
- Trial name
- IMT (NCT02243527)
- Testing
- Inspiratory Muscle Training
- Where
- Canada
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Chronic Obstructive Pulmonary Disease (COPD), Asthma
A Study to Evaluate the Disposition of Drug in Body and Safety After Administration of Single Inhaled Doses of Drugs Abediterol and AZD7594 Administered Alone, in Fixed Dose Combination and in Free Combination Using the Dry Powder Inhaler in Healthy Male Participants
AZD7594 is a non steroidal, potent and selective modulator of the glucocorticoid receptor (GR) under development for once daily inhaled treatment of chronic obstructive pulmonary disease (COPD) and asthma.
- Trial name
- NCT02967159
- Testing
- Abediterol, AZD7594, AZD7594/abediterol
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Asthma, Healthy Volunteers
A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Repeat Doses of RV6153
RV6153 is a new medicine being developed for possible treatment of asthma and smoking related lung disease (also known as chronic obstructive pulmonary disease - COPD).
- Trial name
- NCT02517359
- Testing
- RV6153 single dose, RV6153 14 day repeat dose, RV6153 28 day repeat dose
- Where
- 2 sites in United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Respivert Ltd
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 3 of 7)
NOTE: This is the third of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02882542
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Bern
Exercise, Pulmonary Rehabilitation
The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis
The goal of this observational study is to examine the effects of traditional respiratory rehabilitation and respiratory muscle strengthening training added to this program at the genetic level in in patients with rheumatoid…
- Conditions
- Exercise, Pulmonary Rehabilitation, Interstitial Lung Disease, Long Noncoding RNA
- Trial name
- NCT07320846
- Testing
- Standard pulmonary rehabilitation programme, Resistive threshold inspiratory muscle training, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cannabis, Cardiovascular Risk Factor
Cannabis Inhalation: Effects on Cardiovascular Function During Rest and Exercise
This two-phase project seeks to examine the cardiovascular response to consumption of cannabis variants of different cannabinoid composition through different methods (smoking vs. vaporizing), at rest and during aerobic exercise.
- Trial name
- NCT04693884
- Testing
- Cannabis
- Where
- Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Jamie Burr
Insomnia
Abdominal Breathing on Improving of Sleep Quality and Physiological Index Among Patients With Insomnia
The research topic is to explore the effectiveness of abdominal breathing on improving of sleep quality and physiological index (heart rate, respiration rate and blood pressure) among patients with insomnia.
- Trial name
- NCT05581355
- Testing
- Abdominal breathing training
- Where
- Taiwan
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Glenohumeral Internal Rotation Deficit (GIRD), Pelvic Alignment
Immediate Effects of Postural Restoration Exercises and Breathing on Shoulder and Pelvic Mobility
Prolonged sedentary behavior and habitual poor posture often lead to asymmetrical muscular loading and restricted joint mobility, such as glenohumeral internal rotation deficit (GIRD).
- Conditions
- Glenohumeral Internal Rotation Deficit (GIRD), Pelvic Alignment, Breathing Mechanics
- Trial name
- PRE-DISM (NCT07910578)
- Testing
- Postural Restoration Exercises, Positional Exercises, Breathing Exercises
- Where
- Taiwan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fooyin University
Hearing Loss, Complete
Evaluation of a Bio-inspired Coding Strategy for Cochlear Implant Users
This study will determine the facilitation, refractoriness and spatial spread effects of auditory nerve fiber responses to electrical stimulation via a cochlear implant.
- Trial name
- EBCS (NCT03726684)
- Testing
- Coding strategy for cochlear implants
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Hemorrhoid Pain
Post Hemorrhoidectomy Anorectal Pain
This is a quality assurance trial to evaluate the effectiveness of guided breathing exercises on reducing the symptoms of hemorrhoidal disease in colorectal surgery patients.
- Trial name
- NCT03240185
- Testing
- deep breathing exercises
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Diabetic Foot, Resistance Exercise
Breathing-based Leg Resistance Exercise Improves Wound Healing, Blood Sugar and Quality of Life for Diabetic Foot Ulcers
The purpose of the study was designed leg resistance training combined with breathing approach, and evaluated its effect on wound healing, blood sugar control and quality of life in type 2 diabetic patients with foot ulcers.
- Conditions
- Diabetic Foot, Resistance Exercise, Wound Healing, Hyperglycemia
- Trial name
- NCT05110092
- Testing
- leg resistance combined with breathing exercise training
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
COVID-19 Pneumonia, Respiratory Disease
The Effect of Deep Breathing and Cough Exercise on Respiratory Parameters in Patients With Covid-19 Associated Pneumonia
Studies reveal that the Covid-19 virus can be transmitted in three ways: respiratory tract, direct contact and feces. The incubation period is estimated to be 5.2 [4.1-7.0] days for the 95% confidence interval and the virus…
- Trial name
- NCT05218200
- Testing
- deep breathing and coughing exercises with triflo
- Where
- Turkey (Türkiye)
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Özge Uçar
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