Clinical trials: Inhalation
Work Related Stress
Somatic Psychoeducational Intervention
The goal of this clinical trial is to explore possible benefits and mechanisms through which the Somatic Psychoeducational Intervention can improve health and wellness.
- Trial name
- NCT06580119
- Testing
- Somatic Psychoeducational Intervention
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Asthma
Safety, Tolerability, and Pharmacokinetics After Multiple Doses of Orally Inhaled DNAzyme Solution for Nebulisation in Healthy Male Subjects
Asthma is a chronic inflammatory bronchial disorder with three distinct components: airway hyper-responsiveness (respiratory hypersensitivity), airway inflammation, and intermittent airway obstruction.
- Trial name
- NCT01554319
- Testing
- SB010
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Sterna Biologicals GmbH & Co. KG
Cough
The Safety, Tolerability, PK and PD of GSK2339345 in Healthy Subjects
This is a First Time in Human (FTIH) study for the sodium channel inhibitor, GSK2339345. The study is split into two parts. Part A will assess the safety and tolerability of the new drug.
- Trial name
- FTIH (NCT01494636)
- Testing
- GSK2339345 (solution), GSK2339345 (nebulised), Lidocaine
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Periodontal Diseases
Clinical Assessment of Chitosan Nanoparticles on Periodontal Problems Post Steroidal Inhalation in Asthmatic Patients: Phase I Trial
Periodontal problems management is the most important goals of chronic asthmatic patients that adapted to use steroid inhalation for long time.
- Trial name
- NCT06525363
- Testing
- Chitosan
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Deraya University
Dyspnea During Pregnancy, Physiological Changes in Pregnancy
Breathing Exercises Versus Incentive Spirometry in Third-Trimester Pregnancy
Shortness of breath (dyspnea) is commonly experienced during the third trimester of pregnancy due to physiological changes affecting the respiratory system.
- Conditions
- Dyspnea During Pregnancy, Physiological Changes in Pregnancy, Reduced Functional Endurance
- Trial name
- NCT07365163
- Testing
- Deep Breathing Exercises, Volume-Oriented Incentive Spirometry
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Aging
The Effect of Age and Inspiratory Resistance on the Inspiratory Gas Levels While Wearing Air Purifying Respirator "
20 healthy young subjects and 20 healthy older subjects will go through a medical examination. Subjects will be asked for their medical history especially on respiratory and cardiac diseases.
- Trial name
- NCT03522493
- Testing
- "Yaalom Katom"
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Nursing Students
The Effect of 4-7-8 Breathing Exercise Training on Sleep Quality
Research; it will be carried out Kilis 7 Aralik University Yusuf Serefoglu Health Sciences Faculty, Department of Nursing. The training will take approximately 20 minutes in an empty classroom and will be planned when the…
- Trial name
- NCT06103344
- Testing
- 4-7-8 Breathing Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Uğur Doğan
Healthy
Influence of an Inspiratory Muscle Fatigue Protocol on Healthy Youngs on Respiratory Muscle Strength and Heart Rate Variability
Respiratory muscle training represents an effective method increasingly utilized in both sports and healthcare domains, employing various devices, among which threshold devices are prominent.
- Trial name
- NCT06278714
- Testing
- Inspiratory muscle training
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Hyperbaric, Diving Medicine
Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air
Primary objective: Assessment of venous gas emboli load post diving when breathing normobaric oxygen compared to air. Secondary objective: Assessment of fluid markers of central nervous system injury in blood post diving…
- Conditions
- Hyperbaric, Diving Medicine, Decompression Sickness, Central Nervous Injury
- Trial name
- NCT02468752
- Testing
- Oxygen, Air
- Where
- 2 sites in Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Symptoms and Signs
Yoga-Based Breathing Exercise, Colorectal Cancer Surgery
This study was designed as a prospective, parallel two groups and randomized controlled study with an experimental-control group to evaluate the effect of yoga-based breathing exercise on pain, fatigue, insomnia and self-efficacy…
- Trial name
- NCT06446999
- Testing
- Yoga-Based Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Drug Safety, Respiratory Syncytial Virus Infections
A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of MDT-637 in Healthy Volunteers
The purpose of this study is to determine the range of single inhaled doses of a new dry powder product, MDT-637, that are safe and well-tolerated.
- Trial name
- NCT01355016
- Testing
- MDT-637
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- MicroDose Therapeutx, Inc
Forward Head Posture
Effects of Cervical Spine Retraction Exercise With and Without Diaphragmatic Breathing in Forward Head Posture.
This study aims to determine the effect of combining diaphragmatic exercises with cervical retraction exercise on pain, disability, active range of motions of cervical spine and craniovertebral angle in individuals with forward…
- Trial name
- NCT06130969
- Testing
- Cervical Retraction Exercise, Diaphragmatic Breathing, Baseline Treatment
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Asthma
A Study to Evaluate the Sensitivity and Specificity of Inhaled Methacholine in Bronchial Provocation Test
A multicenter, open-label study to evaluate the sensitivity and specificity of inhaled methacholine in bronchial provocation test
- Trial name
- NCT05634473
- Testing
- Methacholine Chloride
- Where
- 12 sites in China
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Children, Breathing Patterns
Animation-Based Breathing Therapy for School-Age Children
This randomized controlled trial aims to investigate the efficacy of animation-based breathing therapy on the physical (cough strength, chest expansion, and walking speed) and psychological health (perceived stress level…
- Conditions
- Children, Breathing Patterns, Stress, School Health
- Trial name
- NCT06988254
- Testing
- Animation-based breathing therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Low Skeletal Muscle Mas
High- and Moderate-Intensity Inspiratory Muscle Training on Diaphragm Ultrasound Parameters, Cognition, and Mental Health
Low skeletal muscle mass during young adulthood may impair diaphragm function, cognition, sleep, and psychological well-being. Inspiratory muscle training (IMT) has been shown to improve respiratory muscle performance; however…
- Trial name
- NCT07757139
- Testing
- High-Intensity IMT, Moderate-Intensity IMT
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Postmenopause
Effects of Breathing Training on Psychosocial Functioning and Heart Rate Variability in Postmenopausal Women With Depressive Symptoms-2
The specific aims of this study are: 1. To develop a breathing training protocol specifically designed to improve HRV and psychosocial functioning for postmenopausal women with depressive symptoms, 2.
- Trial name
- NCT01046149
- Testing
- Breathing training, Stress management
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Science and Technology Council, Taiwan
Manual Ventilation
Prolonged Manual Ventilation Simulation
A pilot study on simulated lung scenarios using the standard manual resuscitator bag, flow limiting resuscitator bag, and an FDA approved flow rate limiting device paired with a standard manual resuscitator.
- Trial name
- NCT06805838
- Testing
- Sotair
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- SafeBVM
COPD
Investigate the Safety, Tolerability and Pharmacokinetics of CHF6523 in Healthy and in COPD Subjects
This study is designed to investigate the safety, tolerability and pharmacokinetics of inhaled CHF6523 DPI in healthy male subjects first and then in COPD subjects after single or repeated dosesof CHF6523.
- Trial name
- CHF6523 (NCT04032535)
- Testing
- CHF6523
- Where
- United Kingdom
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Chiesi Farmaceutici S.p.A.
Stress Reduction, Psychological Wellbeing
The Concert Therapy Pilot Study for Stress Reduction and Wellbeing
The Concert Therapy is an arts-based, pilot interventional study designed to explore the effects of live music, guided breathing, and movement on stress reduction and overall wellbeing.
- Conditions
- Stress Reduction, Psychological Wellbeing, Mental Health, Music Therapy
- Trial name
- TCT (NCT07236918)
- Testing
- The Concert Therapy
- Where
- United Kingdom
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- BeHnam KhodaRahmi
COPD, Asthma
Cardiorespiratory Diagnostic Study
This study uses a new breathing device called 'N-Tidal C' handset which measures breathing patterns. Investigators have found that people with cardiac and respiratory illnesses breathe out a gas, called carbon dioxide (CO2), in a…
- Conditions
- COPD, Asthma, Lung Cancer, Anemia
- Trial name
- CARES (NCT04939558)
- Testing
- N-Tidal C handset
- Where
- United Kingdom
- Volunteers
- 744 people, healthy volunteers welcome
- Sponsor
- TidalSense
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