Clinical trials: Inhalation
Healthy Volunteers
Clinical Study of DMT in Healthy Adults
This study aims to evaluate the acute and subacute effects of an inhaled N, N-Dimethyltryptamine in healthy individuals.
- Trial name
- NCT05573568
- Testing
- N,N-Dimethyltryptamine
- Where
- Brazil
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Biomind Labs Inc.
Healthy Adults, Inspiratory Muscle Training
The Effect of Foam Roller Applied to the SCM Muscle on Respiratory Muscle Fatigue
The aim of this study is to examine the acute effect of the foam roller (FR) method applied to the sternocleidomastoid (SCM) muscle after respiratory muscle fatigue on joint range of motion (ROM), accessory respiratory muscle…
- Trial name
- NCT06411782
- Testing
- Foam roller, Inspiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Healthy
A Study in Healthy Men That Tests if Taking BI 1265162 by Mouth, Intravenously, or Inhaled Influences the Amount of BI 1265162 in the Blood
The main objective of this trial is to investigate the absolute bioavailability of BI 1265162 following administration of oral solution and inhaled (with and without charcoal) via Respimat.
- Trial name
- NCT03907280
- Testing
- BI 1265162 (T1), BI 1265162 (T2), BI 1265162 (R)
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Pulmonary Disease, Chronic Obstructive
Effects of Tiotropium on Breathing Capacity and Exercise Limitation in Early Stages of Chronic Obstructive Pulmonary Disease
Optimal clinical management in early stages of COPD is not established. Tiotropium has been shown to improve exercise tolerance during (CWR) cycle ergometry with GOLD stage II to IV COPD, improvements in constant speed treadmill…
- Trial name
- NCT01072396
- Testing
- Tiotropium
- Where
- 15 sites in United States, Canada
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Magnetic Resonance Spectroscopy Studies of Acute Hypoxic and Hyperoxic Breathing in Healthy Volunteers
This study evaluates the impact of hypoxic and hyperoxic breathing on measures of brain redox balance and metabolism in healthy individuals.
- Trial name
- NCT03106376
- Testing
- 16% O2 gas in breathed air, 26% O2 gas in breathed air
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mclean Hospital
Pre-hypertension
Tension Tamer Randomized Control Trial
This study is 12 months long and consists of 5 visits at baseline, months 1, 3, 6, and 12. To determine eligibility potential subjects will have resting blood pressures (BP) measured on 2 occasions.
- Trial name
- NCT03168789
- Testing
- Tension Tamer (TT), Lifestyle education program (SPCTL)
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Obstructive Sleep Apnea
Obstructive Sleep Apnea Among Somali-Americans
The investigators seek to advance the understanding of obstructive sleep apnea as it relates to different ethnic origins as well as sex differences.
- Trial name
- Somali OSA (NCT04124848)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Esports, Caffeine
Effects of Caffeine, L-Theanine, and Diaphragmatic Breathing on Esports Players' Performance
The purpose of this study is to investigate whether caffeine, L-theanine (a natural amino acid found in tea), and diaphragmatic breathing exercises can help improve the game performance of esports players.
- Conditions
- Esports, Caffeine, L-theanine
- Trial name
- CLD Esports St (NCT06621797)
- Testing
- Intervention 1: Dietary Supplement - Caffeine Supplement, Intervention 2: Dietary Supplement - Caffeine + L-Theanine Supplement, Intervention 3: Dietary Supplement - Caffeine Supplement + Diaphragmatic Breathing Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy
Cardiovascular Consequences of Inhaled Short-acting Beta-agonist Use
The goal of this clinical trial is to test the impact inhalers have on blood vessels in young healthy individuals. The main question it aims to answer is if long term use of asthma inhalers have any effect on the blood vessels…
- Trial name
- NCT06027606
- Testing
- Salbutamol 400mcg, Budesonide/formoterol
- Where
- Canada
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Covid19
Covid-19 Virtual Recovery Study
The purpose of this study is to determine the effects of respiratory muscle training (RMT) and nasal breathing on patients who have been infected with the SARS-CoV2 virus and continue to have lingering symptoms.
- Trial name
- NCT04950725
- Testing
- Strength RMT, Strength RMT and nasal breathing, Endurance RMT
- Where
- United States
- Volunteers
- 2,268 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Asthma, Obesity
Study of the Physiology of the Asthma of the Obese Subjects. Breathing Obesity Asthma Study (BOA)
Asthma is more frequent in obese women, but the mechanisms underlying the causes of this increased frequency are unknown and are different from usual asthma pathophysiology (associated with allergy).
- Trial name
- BOA (NCT00577733)
- Where
- France
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bone Marrow Cancer
The Effect of Relaxing Breathing Exercise Applied to Patients Before Bone Marrow Biopsy on Vital Signs, Pain and Anxiety Levels
There is no study in the literature that determined the effect of relaxing breathing exercise applied to patients before the BMB procedure on vital signs, pain and anxiety levels.
- Trial name
- NCT05632874
- Testing
- relaxing breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Post-Traumatic Stress Symptoms, Poor Sleep Quality
Psychoeducation-Supported Breathing and Relaxation for Earthquake Survivors
This randomized controlled study evaluated whether a structured program combining psychoeducation, breathing exercises, and relaxation techniques could reduce post-traumatic stress symptoms and improve sleep quality among adult…
- Trial name
- NCT07781904
- Testing
- Psychoeducation-Supported Breathing and Relaxation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rana Ceviz
Older Adults (60 - 85 Years Old)
Multiple Breathing Training on Pulmonary Function and Respiratory Muscle Strength in Older Adults
This study were to investigate the effects of multiple breathing training on pulmonary function, respiratory muscle strength, chest expansion, fractional exhaled nitric oxide (FeNO), aerobic capacity, and dyspnea symptoms in…
- Trial name
- NCT07459153
- Testing
- Multiple breathing training
- Where
- Thailand
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Close Contact Transmission
Exploratory Study of Aerosol Inhalation of FB2001 for Post-exposure Prophylaxis of COVID-19 Close Contacts
This is a single-arm, open-label, dose ramp-up exploratory clinical trial to evaluate the efficacy, safety and tolerance of aerosol inhalation of FB2001 as post-exposure prophylaxis among close contacts of COVID-19 patients.
- Trial name
- NCT05415241
- Testing
- FB2001
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Covid19
Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Inhaled APN01 Developed as Treatment for COVID-19
APN01 is a soluble recombinant form of the human angiotensin-converting enzyme 2 (rhACE2) that is currently under development as a therapy for corona-virus-disease 2019 (COVID-19).
- Trial name
- NCT05065645
- Testing
- Angiotensin Converting Enzyme 2, Sodium chloride
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Apeiron Biologics
Asthma
Staccato Loxapine Pulmonary Safety in Patients With Asthma
The purpose of this study is to assess the safety of 2 inhaled doses of Staccato Loxapine within a day in patients with asthma.
- Trial name
- NCT00890175
- Testing
- Inhaled loxapine @ 0 & 10 h
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Alexza Pharmaceuticals, Inc.
Atopic Asthma, Healthy
Differential Gene Expression in Lung and Peripheral Blood After Inhaled Allergen Challenge
The purpose of this study is to identify the genes in important airway cells that are specifically expressed following inhalation of house dust mite allergen among study subjects with either allergic asthma or healthy normal…
- Trial name
- NCT00671593
- Testing
- House Dust Mite, Diluent
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- John Sundy
Healthy Volunteers
Comparison of the Effect of Different Inspiratory Loads on Diaphragmatic Function in Healthy Individuals
This pilot study aims to evaluate how the diaphragm responds to different inspiratory muscle training loads using ultrasound in healthy individuals.
- Trial name
- NCT07143721
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Chest Pain, Sickle Cell Anemia
Effects of Nitric Oxide and Nitroglycerin in Patients With Sickle Cell Anemia
Sickle cell anemia is the most common genetic disease affecting African-Americans. About 1 in every 1000 African-Americans has the disease and 1 in every 12 carry the genes that could be passed on to their children.
- Trial name
- NCT00001716
- Testing
- Nitric Oxide, Nitroglycerin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
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