Clinical trials: Inhalation
Periodic Breathing, Heart Failure
The Cyclocapnic Method for Measurement of Chemosensitivity
We aim to test our method for measuring chemosensitivity (the ventilatory response to a change in carbon dioxide), which uses sinusoidal carbon dioxide stimuli.
- Trial name
- NCT01049256
- Testing
- carbon dioxide
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Heart Failure
The Effects of Inspiratory Muscle Training in Patients With Heart Failure With Preserved Ejection Fraction
Previous studies have evaluated the effects of inspiratory muscle training in patiens with heart failure and reduced ejection fraction; nevertheless,no evidence endorse the therapeutic role of inspiratory muscle training in…
- Trial name
- NCT01707277
- Testing
- Inspiratory muscle training, Usual care
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Asthma
Pharmacokinetic Clinical Study of CHF1535 NEXT DPI® Versus CHF1535 pMDI
The aim of this clinical study is to compare the lung exposure of the contents of the trial drug after administration of the fixed combination between beclomethasone and formoterol delivered via the new Chiesi dry powder inhaler…
- Trial name
- NCT01349257
- Testing
- BDP/Formoterol
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Mechanical Ventilation
Mechanical Ventilation in Multiple Fracture Ribs
Chest trauma is the most common injury in the emergency trauma and rib fractures is the most common trauma in chest trauma. Severe rib fractures can cause paradoxical respiration and mediastinal swing, which has large effects on…
- Trial name
- NCT03314701
- Testing
- Biphasic Intermittent Positive Airway Pressure (BIPAP), Airway Pressure Release Ventilation (APRV)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Breathing, Mouth, Lung Function Decreased
Cardiopulmonary Exercise Testing and Oscillometry for the Evaluation of Dyspnea
This study will determine if airway resistance to airflow and pressure, measured by Oscillometry, is associated with abnormal findings on Cardiopulmonary Exercise Testing in subjects who are experiencing shortness of breath.
- Conditions
- Breathing, Mouth, Lung Function Decreased, Dyspnea, Shortness of Breath
- Trial name
- COED (NCT06554353)
- Testing
- Oscillometer
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Rochester
Ventilator-Induced Lung Injury, Acute Respiratory Distress Syndrome
Comparing Mechanical Power in Different Inspiratory Times
We aimed to compare mechanical power and energy values using geometric methods at varying inspiratory rise times.
- Trial name
- NCT06413472
- Testing
- Mechanical ventilator adjustment for PCV, Mechanical ventilator adjustment for VCV
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Cystic Fibrosis, Rhinosinusitis
Sino-nasal Inhalation of Sodium Chloride 6,0% in Patients With Cystic Fibrosis and Chronic Rhinosinusitis
Rhinosinusitis disorders are almost regularly associated to Cystic Fibrosis (CF). The basic defect in CF is a dysfunction of chloride channels in exocrine glands which equally concerns upper airway mucosa.
- Trial name
- NCT01086839
- Testing
- sodium chloride 6%, sodium chloride 0,9%
- Where
- 11 sites in Germany
- Volunteers
- 69 people
- Sponsor
- University of Jena
Diabetes, Gastric Content Aspiration
Effects of GLP-1 Agonists on Gastric Volume
This study will enroll patients ages 18 and over who have a diagnosis of diabetes, are undergoing an elective surgery under general anesthesia and 1) are taking a GLP-1 receptor agonist medication, or 2) not taking a GLP-1…
- Conditions
- Diabetes, Gastric Content Aspiration, Glucagon-like Peptide 1, GLP-1
- Trial name
- NCT05854979
- Testing
- Gastric Ultrasound
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Medical University of South Carolina
Contraception, Inhalation of Nitrous Oxide
Nitrous Oxide for Pain Management During In-office Transcervical Sterilization
This is a randomized, double blind study that aims to measure the difference in maximum pain experienced during in-office transcervical sterilization (Essure®) for women receiving either inhaled nitrous oxide or standard oral…
- Trial name
- NEST (NCT02312739)
- Testing
- In-office Transcervical Sterilization (Essure®), Standard Oral pain medications, Intramuscular Ketorolac
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Sleep Apnea, Heart Failure
Effects of Nocturnal Nasal Oxygen on Biomarkers in Sleep Apnea Patients With Heart Failure
Sleep apnea syndrome is clinically defined by frequent pauses in breathing during sleep and symptoms, such as being tired. It can decrease the restfulness of sleep and decreases the level of oxygen in the blood.
- Trial name
- NCT01431157
- Testing
- Nocturnal nasal oxygen, No nasal oxygen
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Maryland, Baltimore
Healthy
Phase I Safety Study of Inhaled N-IP-00001 to Determine Tolerability and Safety in Healthy Volunteers.
Randomized, double-blind, placebo-controlled, dose-escalation Phase I safety study of inhaled N-IP-00001, to determine tolerability and safety in healthy volunteers.
- Trial name
- NCT06662019
- Testing
- N-IP-00001 inhalation solution, 0.9% NaCl isotonic saline solution
- Where
- 2 sites in Australia
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- NeoTrials Pty Ltd
Colorectal Cancer, Respiratory Function
Functional and Respiratory Determinants of Long-Term Colorectal Cancer Outcomes
Colorectal cancer is one of the most commonly diagnosed malignancies worldwide and a leading cause of cancer-related morbidity and mortality.
- Conditions
- Colorectal Cancer, Respiratory Function, Functional Status, Long Term
- Trial name
- NCT07523919
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Inonu University
Pulmonary Disease, COPD
Reducing Dynamic Hyperinflation Through Breathing Retraining
This study will compare the effects of exercise training and breathing retraining (using metronome tones) to exercise training only. Exercise training lasts 12 weeks.
- Trial name
- NCT01009099
- Testing
- breathing retraining, exercise training
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- US Department of Veterans Affairs
Asthma
An Effectiveness Study Comparing Fluticasone Furoate (FF, GW685698)/Vilanterol (VI, GW642444) With Standard Treatment in Asthma
This study is designed to compare the effectiveness and safety of Fluticasone Furoate/Vilanterol Inhalation Powder (100mcg Fluticasone Furoate ((FF), GW685698)/25mcg Vilanterol ((VI), GW642444) or 200mcg Fluticasone Furoate…
- Trial name
- NCT01706198
- Testing
- fluticasone furoate + vilanterol, inhaled corticosteroid with or without a long acting beta2-agonist
- Where
- 180 sites in United Kingdom
- Volunteers
- 4,233 people
- Sponsor
- GlaxoSmithKline
Healthy Smokers
Effect Of Deep Breathing Exercises In Smokers
To determine the effect of deep breathing exercises on lung function in healthy smokers.
- Trial name
- NCT03728530
- Testing
- Deep Breathing exercises
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Isra University
Weaning Failure
Comparison of Two Different Types of Mechanical Ventilation Weaning in Patients in the ICU
Mechanical ventilation is widely used for ICU patients as a lifesaving procedure. However, it is associated with several complications, such as ventilator-associated pneumonia and the increase of hospital morbidity and mortality.
- Trial name
- NCT02122016
- Testing
- SmartCare, Conventional weaning protocol
- Where
- 2 sites in Brazil
- Volunteers
- 70 people
- Sponsor
- Hospital Israelita Albert Einstein
Persistent Pulmonary Hypertension of the Newborn, Hypoxic Respiratory Failure
Post Market Clinical Follow-up to Assess the Portable Nitric Oxide Generation and Delivery System (INOwill N200) for the Treatment of Neonatal Hypoxic Respiratory Failure Complicated by Pulmonary Hypertension
Title : A multicenter clinical trial of the portable nitric oxide generation and delivery system (INOwill N200) for the treatment of neonatal hypoxic respiratory failure complicated by pulmonary hypertension Investigational…
- Trial name
- iNOwill Neonat (NCT07837921)
- Testing
- Nitric Oxide Generator and Delivery System
- Volunteers
- 50 people
- Sponsor
- Novlead Inc.
Asthma
A Dose Range-Finding Study to Assess the Efficacy and Safety of Multiple Dose Levels of AZD8630 in Adults With Uncontrolled Asthma at Risk of Exacerbations
A dose range-finding study to assess the efficacy and safety of multiple dose levels of AZD8630 administered via a dry powder inhaler in adults with uncontrolled asthma at risk of exacerbations, receiving medium -to -high dose…
- Trial name
- Levante (NCT06529419)
- Testing
- AZD8630, Inhaler
- Where
- 196 sites in United States, Argentina and 21 more
- Volunteers
- 537 people
- Sponsor
- AstraZeneca
Pulmonary Vascular Disease
Non-Invasive Diagnosis of Pulmonary Vascular Disease Using Inhaled 129Xe Magnetic Resonance Imaging
This study seeks to deploy several forms of 129Xe MRI contrast as well as emerging conventional proton MRI technqiues for imaging lung structure and perfusion.
- Trial name
- XenonMRI (NCT03078192)
- Testing
- GE-141, Hyperpolarized 129Xenon gas, MRI
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Bastiaan Driehuys
Inadequate or Impaired Breathing Pattern or Ventilation, Difficult Intubation
Difficult Bag Mask Ventilation and Difficult Intubation in Children
Unanticipated difficult airway comprises of unexpected difficult bag mask ventilation or unforeseen difficult laryngoscopy. The incidence of difficult laryngoscopy or unanticipated difficult intubation in children was varied from…
- Conditions
- Inadequate or Impaired Breathing Pattern or Ventilation, Difficult Intubation, Anesthesia; Adverse Effect
- Trial name
- NCT02823392
- Testing
- DBMV
- Where
- Thailand
- Volunteers
- 765 people
- Sponsor
- Prince of Songkla University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.