Clinical trials: Inhalation
Covid19, Hypertension
Inspiratory Muscle Trainer and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) COVID-19 Persistent Symptoms
Inspiratory muscle training considered as safe and valid method to improve respiratory muscle strength and functional capacity among uncountable conditions which could improve post COVID-19 persistent symptoms including but not…
- Conditions
- Covid19, Hypertension, Corona Persistent Symptoms
- Trial name
- NCT04919031
- Testing
- Inspiratory muscle trainer, diaphragmatic release
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Respiratory Syncytial Virus Infections
A Study of PC786 to Evaluate the Antiviral Activity, Safety and Pharmacokinetics of Multiple Doses in an RSV Challenge Study
PC786 is a new medicine being developed for treatment of respiratory syncytial virus. The main purpose of this study is to evaluate the antiviral activity of PC786 in healthy adults infected with RSV virus in a viral challenge…
- Trial name
- NCT03382431
- Testing
- PC786
- Where
- United Kingdom
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Pulmocide Ltd
Angina, Stable
Effectiveness of Inspiratory Muscle Training in Patient With Stable Angina
Stable angina is a cardiac pathology that adversely affects the quality of life of the patient, which develops as a result of narrowing of the coronary vessels developing in atherosclerotic ground and / or impaired oxygen…
- Trial name
- NCT03923153
- Testing
- Inspiratory muscle training with PowerBreathe (IMT Technologies Ltd., Birmingham,England)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Mustafa Kemal University
Axial Spondyloarthritis (AxSpA)
Inspiratory Muscle Training in Axial Spondyloarthritis
This study investigated the effects of inspiratory muscle training (IMT) combined with aerobic exercise on diaphragm function, disease activity, functional exercise capacity, fatigue, sleep quality, and health-related quality of…
- Trial name
- NCT07914439
- Testing
- Aerobic Exercise, Conventional Spinal Mobility Exercises, Inspiratory Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Asthma
Crossover Study to Evaluate the Efficacy, Safety and Tolerability of Different Doses of Indacaterol in Patients With Persistent Asthma
The purpose of this study is to determine the efficacy of indacaterol 55µg once daily (and 27.5 µg twice) in QVA149 compared to 75 µg indacaterol monotherapy.
- Trial name
- QAB149 (NCT01959412)
- Testing
- Indacaterol 27.5 mcg, Indacaterol 37.5, Indacaterol 55 mcg
- Where
- 12 sites in United States
- Volunteers
- 91 people
- Sponsor
- Novartis Pharmaceuticals
Anxiety
Abdominal Breathing Training on Reducing Anxiety
The research purpose is to investigate the effectiveness of abdominal breathing training on reducing anxiety. This study is an experimental research design. Using a randomized controlled trial approach.
- Trial name
- NCT04704765
- Testing
- abdominal breathing training
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Taipei University of Nursing and Health Sciences
Diabetes Mellitus, Chronic Obstructive Pulmonary Disease
A One Year Clinical Trial Assessing the Usefulness and Safety of Inhaled Insulin in Diabetics With COPD
A One Year Clinical Trial Assessing the Usefulness and Safety of Inhaled Insulin in Diabetics with Chronic Obstructive Pulmonary Disease.
- Trial name
- NCT00138671
- Testing
- Subcutaneous Insulin, Inhaled Insulin
- Where
- 88 sites in United States, Brazil and 3 more
- Volunteers
- 105 people
- Sponsor
- Pfizer
Prostate Cancer
A Comparison of Totally Intravenous and Inhalation Anesthesia for Intraocular Pressure During Robot-Assisted Laparoscopic Radical Prostatectomy
Robot-assisted laparoscopic radical prostatectomy (RALRP) has gained popularity during the past decade and has widely replaced conventional open prostatectomy in many institutions due to reduced blood loss, nerve sparing, less…
- Trial name
- NCT01744262
- Testing
- Total intravenous anesthesia, Inhalation Anesthesia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Burns (Physical Finding)
Mechanical Ventilation With and Without Postural Drainage in Burn Patients With ARDS
Inhalation injury become a more common cause of death in burn patients but alone the smoke injury has low mortality rate. It is reported that a combination of smoke injury with cutaneous burn increases the mortality rate and…
- Trial name
- NCT05321888
- Testing
- Mechanical Ventilation, Mechanical Ventilation with Postural drainage
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Respiratory Function Tests, Anesthesia, General
PSV on Ventilation Inhomogeneity and Lung Function in Patients Under SB Across LMA
General anesthesia has been demonstrated to have a negative impact on lung function. Both surgery and patient position influence the perioperative lung function.
- Conditions
- Respiratory Function Tests, Anesthesia, General, Patient Positioning, Ventilation
- Trial name
- VINHO (NCT02986269)
- Testing
- general anesthesia across LMA, Spontaneous breathing(SB), Pressure Support Ventilation
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Walid HABRE
Covid19
Inhaled Heparin for Hospitalised COVID-19 Patients
This meta-trial is a prospective collaborative individual participant data meta-analysis of randomised controlled trials and early phase studies.
- Trial name
- INHALE-HEP (NCT04635241)
- Testing
- Unfractionated heparin
- Where
- 5 sites in Argentina, Egypt and 1 more
- Volunteers
- 485 people
- Sponsor
- Australian National University
Sleep Disordered Breathing, Tetraplegia
Sleep Disordered Breathing
Sleep-disordered breathing (SDB) occurs in 2% to 4% of the non-disabled adult population and is characterized by periods of complete breathing cessation (apnea) or marked reductions in airflow (hypopnea) during sleep.
- Trial name
- SDB (NCT01467856)
- Testing
- PAP Device Procedure
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Mark S. Nash, Ph.D., FACSM
Diabetes Mellitus, Stress
Effect of Breathing and Relaxation Exercises on Serum Cortisol Levels in Type 2 Diabetic Patients
Background: Diabetes is a fast-growing health problem in Egypt with a significant impact on morbidity, mortality, and health care resources.
- Trial name
- NCT05231031
- Testing
- Aerobic exercise, breathing exercise, Relaxation training
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Respiratory Infections, Acute, Respiratory Tract Diseases
The Effect of Virtual Reality Goggles and Distraction Cards Applied to Children Aged 6-12 Years During Inhaler Therapy on Physiological Parameters and Anxiety
In the literature, studies examining the effect of virtual reality application on physiological parameters and anxiety during inhalation therapy, which is frequently used in children, are quite limited.
- Trial name
- NCT06893237
- Testing
- virtual reality goggles and inhalation treatment, distraction cards and inhalation therapy, inhalation therapy
- Volunteers
- 108 people
- Sponsor
- Uskudar University
Myasthenia Gravis
Interval Inspiratory Training and Aerobic Exercise for Muscle Recovery in Myasthenia Gravis Post-Hospitalization
The goal of this clinical trial is to determine whether inspiratory muscle training aids in the recovery of respiratory muscle strength and helps prevent further muscle weakness in patients with myasthenia gravis.
- Trial name
- NCT06624345
- Testing
- Inspiratory muscle training, Control Group
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Chang Gung University
Sleep Apnea
Prospective Study of the Impact of Systemic Corticosteroid Use on Measures of Sleep Disordered Breathing
Weight gain is both a significant risk factor for obstructive sleep apnea and a side-effect of long-term systemic steroids therapy. This study aimed to investigate the impact of long-term systemic steroid treatment on sleep apnea.
- Trial name
- NCT01228695
- Testing
- sleep study
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Rambam Health Care Campus
Cardiac Arrest (CA), Cardiopulmonary Resuscitation (CPR)
The OXY-VENT Study
Effective ventilation during cardiopulmonary resuscitation is essential but can be difficult to achieve consistently. Current practice relies on visible chest rise to guide ventilation volume, although this may not always…
- Trial name
- OXY-VENT (NCT07870551)
- Testing
- Ventilation Feedback Device (Active), Control (Recording-Only)
- Where
- Netherlands
- Volunteers
- 515 people
- Sponsor
- Jeroen van Eijk
Obstructive Sleep Apnea, Sleep Disorder (Disorder)
Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation Ablation
Atrial fibrillation (AF) is one of the most common clinical arrhythmias. Catheter ablation is an effective therapeutic strategy; however, recurrence rates remain substantial, ranging from 20% to 45%.
- Conditions
- Obstructive Sleep Apnea, Sleep Disorder (Disorder), Atrial Fibrillation (AF), Sleep Disordered Breathing (SDB)
- Trial name
- STOP-AFib (NCT07444372)
- Testing
- Continuous Positive Airway Pressure (CPAP), Usual Care
- Where
- 30 sites in China
- Volunteers
- 658 people
- Sponsor
- Beijing Anzhen Hospital
Uncontrolled Asthma
Efficacy and Safety of Tanimilast in Asthmatics uNcontrolled on ICS-containinG backgrOund Maintenance Therapy
The purpose of this study is to evaluate the efficacy and safety of CHF6001 (Tanimilast) as add-on to maintenance of inhaled corticosteroids in combination with Long-acting ß2-agonists in the target patient population. (TANGO)
- Trial name
- TANGO (NCT06029595)
- Testing
- Experimental: CHF6001 3200 μg
- Where
- 187 sites in Argentina, Bulgaria and 12 more
- Volunteers
- 517 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Adult Patients, Requiring Intubation
PREoxygenation for the Intubation of Hypoxemic Patients: Comparison of Standard Oxygenation, High Flow Nasal Oxygen Therapy, and NonInvasive Ventilation
Prospective, randomized clinical multicentric study, in ICU, during preoxygenation for the intubation of hypoxemic patients.
- Conditions
- Adult Patients, Requiring Intubation, Hypoxemia (Defined by PaO2/FiO2( Fraction of Inspired Oxygen) Below 200), Patient Covered by French Health Care System
- Trial name
- PREONIV (NCT01782430)
- Testing
- - standard oxygenation
- Where
- France
- Volunteers
- 132 people
- Sponsor
- University Hospital, Clermont-Ferrand
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