Clinical trials: Inhalation Injury
Coronary Artery Disease, Anesthesia
Influence of Oxygen on Perioperative Outcome in Patients Undergoing General Anaesthesia for Elective Non-cardiac Surgery
The purpose of this study is to investigate the impact of supraphysiologic oxygen (hyperoxia) on myocardial function in anaesthetized patients undergoing non-cardiac vascular surgery.
- Trial name
- Promise-O2 (NCT04808401)
- Testing
- Oxygen
- Where
- Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Traumatic Lung Injury, Inhalation Injury
Selecting Specific Bio-markers and Researching Mechanisms of Immune Regulation From Inhalation Injury and Traumatic Lung Injury Based on Single Cell Sequencing Technology
The goal of this observational study is to profile the circulating immunological traits of patients with traumatic lung injury (TLI) and inhalation injury (ILI),providing a new direction for the depth research of the…
- Trial name
- NCT05718830
- Where
- China
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Smoke Inhalation Injury, Burns
Critical Smoke Alarm Characteristics to Awaken Children From Stage 4 Sleep
Specific Aim 1 is to test the hypothesis that there are specific characteristics of a voice smoke alarm (i.e., use of child's first name, behavior commands in the message content, use of mother's voice, and stimulus frequency)…
- Trial name
- NCT01169155
- Testing
- Smoke Alarm Stimuli
- Where
- United States
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Smoke Inhalation
Electronic Cigarette and Surgery (ECigarSurg)
Since decades, literature has shown that smoking has negative effect on postoperative outcome. Recent systematic review and meta-analysis on clinical impact of smoking and smoking cessation showed that postoperative healing…
- Trial name
- ECigarSurg (NCT03594643)
- Where
- France
- Volunteers
- 1,700 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Athletic Injuries
Effects of Inspiratory Muscle Training on Diaphragm Thickness, Respiratory Muscle Strength and Balance in Dancers.
Dance is a performing art form consisting of sports and art intertwined and complex dynamic choreographic figures were handled aesthetically and physically of narrative.
- Trial name
- NCT04845802
- Testing
- Inspiratory muscle training(high-IMT group), Inspiratory muscle training(low-IMT group)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Inhalation Anesthesia, Lung Injury
The Effect of Sevoflurane and Desflurane on Clara Cell Protein on the Lung
Inhalation anesthesia; It means that the anesthetic drugs taken by the respiratory tract pass into the blood through the lung alveoli, reach the brain tissue, and create an anesthetic effect according to the density in the brain…
- Trial name
- NCT04645316
- Testing
- Sevoflurane, Desflurane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Inonu University
Spinal Cord Injury (SCI), Respiratory Complication
Effect of Resistive Inspiratory Muscle Training Optimizing Lung Function in Spinal Cord Injury
The goal of this clinical trial is to evaluate the effectiveness of resistive inspiratory muscle training (RIMT) in optimizing lung function in individuals with spinal cord injury (SCI).
- Trial name
- NCT06547606
- Testing
- Usual Care
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Dhaka
Airway Obstruction, Foreign-Body, Cardiopulmonary Resuscitation
Cardiopulmonary Resuscitation and Choking Management Education for Caregivers of Infants Under 1 Year: Comparison Between Practical Workshop and Informational Leaflet
Objective: to evaluate the effectiveness of an educational workshop versus standard information in improving knowledge and perceived self-efficacy in basic life support.
- Conditions
- Airway Obstruction, Foreign-Body, Cardiopulmonary Resuscitation, Infant, Health Education
- Trial name
- NCT07567638
- Testing
- Explanation of the informational sheet, Theoretical-practical workshop
- Where
- Spain
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Marqués de Valdecilla
Respiratory Disorders
A Study to Investigate the Safety Tolerability Pharmacokinetics, and Pharmacodynamics of Inhaled and Intravenous GSK2862277 in Healthy Volunteers
This will be a 3 part study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of single and repeat doses of GSK2862277 administered via inhalation (IH) or intravenous (IV) routes in healthy subjects.
- Trial name
- NCT01818024
- Testing
- Single IV dose of GSK2862277, Single IH dose of GSK2862277, Repeat IV dose of GSK2862277
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sore-throat, Dysphonia
No Post Intubation Laryngeal Symptoms
The purpose of the study is to test a novel endotracheal tube support device that reduces pressure of the tube on the voice box for prevention of post intubation laryngeal symptoms including sore throat, change in voice and…
- Conditions
- Sore-throat, Dysphonia, Dysphagia, Intubation Complication
- Trial name
- No-PILS (NCT05383417)
- Testing
- EndoClip
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Vasovagal Syncope, Smoke Inhalation
Relation Between Vasovagal Tendency and Smoking Among University Students
Almost everyone is aware these days is aware about the risk of smoking. Still many people start this habit specially in early life and during college year.
- Trial name
- NCT02949804
- Testing
- Comparison between two groups
- Where
- Jordan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Jordan Collaborating Cardiology Group
Work Related Stress
Potential Benefits of the Somatic Psychoeducational Intervention
The goal of this clinical trial is to explore possible benefits and mechanisms through which the Somatic Psychoeducational Intervention can improve health and wellness in health care providers (HCP).
- Trial name
- NCT05766852
- Testing
- Somatic Psychoeducational Intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Florida
Bronchopulmonary Dysplasia, Very Low Birth Weight Infant
Work of Breathing in Premature Infants at Discharge
The purpose of this study is to compare how premature infants who required oxygen for at least 28 days during their time in the NICU (Neonatal Intensive Care Unit) breathe at discharge compared to premature infants who did not…
- Conditions
- Bronchopulmonary Dysplasia, Very Low Birth Weight Infant, Prematurity
- Trial name
- NCT03682575
- Testing
- Enrollment
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Acute Lung Injury (ALI) Associated With COVID-19, Inflammatory Lung Conditions Associated With COVID-19
First in Human SAD and MAD Study of Inhaled TD-0903, a Potential Treatment for ALI Associated With COVID-19
This is a phase 1 study in healthy subjects to evaluate the safety, tolerability and pharmacokinetics of single (Part A and B) and multiple (Part B) doses of inhaled TD-0903.
- Trial name
- NCT04350736
- Testing
- TD-0903
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Theravance Biopharma
Anorexia Nervosa, Major Depressive Disorder
Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa
This study aims to identify the brain regions responsible for encoding cardiorespiratory 'interoceptive' sensations and determine whether they are dysfunctional in individuals affected by eating disorders, anxiety, depression, or…
- Conditions
- Anorexia Nervosa, Major Depressive Disorder, Generalized Anxiety Disorder, Panic Disorder
- Trial name
- NCT02615119
- Testing
- Isoproterenol, Normal saline
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Diabetic Foot, Resistance Exercise
Breathing-based Leg Resistance Exercise Improves Wound Healing, Blood Sugar and Quality of Life for Diabetic Foot Ulcers
The purpose of the study was designed leg resistance training combined with breathing approach, and evaluated its effect on wound healing, blood sugar control and quality of life in type 2 diabetic patients with foot ulcers.
- Conditions
- Diabetic Foot, Resistance Exercise, Wound Healing, Hyperglycemia
- Trial name
- NCT05110092
- Testing
- leg resistance combined with breathing exercise training
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Weaning Failure
Predictive Value of Airway Occlusion Pressure, Maximal Inspiratory Pressure and Their Ratio for Successful Extubation in Patients With Traumatic Brain Injury
The aim of this study will be to measure the predictive power of the respiratory muscle determinants including The maximal inspiratory pressure, and central drive determinant including Airway occlusion pressure and ratio between…
- Trial name
- NCT06627686
- Testing
- Air way occlusion pressure
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Benha University
Cardiovascular Diseases, Particulate Matter Inhalation Injury
Impact of Lifetime Exposure to Air and Noise Pollution on Cardiovascular Disease and Mortality - the AIRCARD Study.
The purpose of this study is to determine the impact of individually lifetime accumulated exposure to air and noise pollution on the incidence and prevalence of cardiovascular diseases (CVD) and mortality.
- Conditions
- Cardiovascular Diseases, Particulate Matter Inhalation Injury, Arteriosclerosis, Pollution; Exposure
- Trial name
- AIRCARD (NCT04353232)
- Where
- Denmark
- Volunteers
- 33,723 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Sports Physical Therapy, Injury;Sports
Inspiratory Muscle Activation and Post-Exercise Recovery in Professional Football Players
Respiratory muscles play a fundamental role in sports performance. Fatigue of these muscles induces changes in maximal inspiratory pressure and autonomic nervous system activity, thereby compromising the athlete's recovery…
- Trial name
- NCT07373158
- Testing
- Inspiratory muscle activation via phrenic nerve modulation, Inspiratory muscle activation via threshold device
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sierra Varona SL
Smoke Inhalation, Exposure, Inhalation
Lung Cancer Screening CT for Firefighters
Firefighters are at increased risk for cancer due to exposure to carcinogenic substances. Current lung cancer screening guidelines are predominantly based on smoking history and do not take into account high risk occupational…
- Conditions
- Smoke Inhalation, Exposure, Inhalation, Exposure to Pollution, Exposure Occupational
- Trial name
- NCT06836414
- Testing
- Low-dose Computerized tomography (CT) of Chest, Questionnaires, Medical History
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco