Clinical trials: Inhalational Anesthesia
Postoperative Recovery, Inhalation Anesthesia
Effect of Combined Intravenous-Inhalational Anesthesia (CIVIA) on Postoperative Recovery Patterns.
This study was planned as a single-center, prospective, randomized trial. Adult patients undergoing elective spinal surgery lasting longer than three hours, performed in a neurosurgery operating room, will be evaluated.
- Conditions
- Postoperative Recovery, Inhalation Anesthesia, Total Intravenous Anesthesia
- Trial name
- NCT07123870
- Testing
- Sevofluorane, Desflurane, Total Intravenous Anesthesia(TIVA)
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Anesthesia, Inhalation; Vapor
Decreasing Environmental Impact and Costs of Using Inhalational Anesthetic With a Carbon Dioxide Membrane Filter System
Efficient inhalational anesthetic delivery requires the use of low-flow air and oxygen to reduce drug waste and minimize workspace contamination and environmental pollution.
- Trial name
- NCT04210570
- Testing
- Memsorb, Chemical granulate absorber
- Where
- Canada
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
General Anesthesia
Vasodilation Effect of Inhalational Anesthetics
Previous studies on animals suggest that inhalational anesthetics can reduce vascular tension in vitro resulting in vasodilation and decrease in blood pressure.
- Trial name
- VEFIHA (NCT00815269)
- Testing
- Halothane, Isoflurane, Sevoflurane
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Nanjing Medical University
Anesthesia, Pediatric ALL
Topical Analgesia Before Inhalational Anaesthesia
Peripheral venous cannulation (insertion of a drip line into a vein) is a fundamental component of anaesthesia for both children and adults alike.
- Trial name
- NCT04959409
- Testing
- Topical analgesia (EMLA or AMETOP)
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Circulating Tumor Cell, Hepatocellular Carcinoma
Effects of TIVA Versus Inhalational Anaesthesia on Circulating Tumour Cells in Hepatocellular Carcinoma Patients
More than 80% of patients with cancer will be exposed to anaesthesia at some point in their treatment. There is increasing evidence that perioperative events, including the type of anaesthesia drugs utilised, have an impact on…
- Trial name
- NCT04601961
- Testing
- Propofol, Sevoflurane
- Where
- China
- Volunteers
- 220 people
- Sponsor
- The University of Hong Kong
Perforated Eardrum
Inhalational Anesthesia vs TIVA in Endoscopic Tympanoplasty
This study aims to prospectively compare surgical field quality and intraoperative blood loss between general inhalational anesthesia to total intravenous anesthesia (TIVA) alone in subjects undergoing endoscopic ear surgery.
- Trial name
- TIVA (NCT05993039)
- Testing
- Isoflurane Inhalant Product, Sevoflurane inhalant product, Propofol injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Our Lady of the Lake Hospital
Laparoscopic Obstetric Surgery
Total Intravenous Anesthesia (TIVA) Versus Inhalational Anesthesia at The End of Laparoscopic Obstetric Surgery Regarding Postoperative Nausea and Vomiting
Postoperative nausea and vomiting (PONV) remain among the most common and distressing complications after general anaesthesia, with important consequences for patient comfort, satisfaction, recovery trajectories, and length of…
- Trial name
- NCT07270289
- Testing
- inhalational anaesthesia, total intravenous anesthesia (TIVA)
- Volunteers
- 98 people
- Sponsor
- Assiut University
Ruptured Cerebral Aneurysm
Effect of Propofol Midazolam on Cerebral Oxygenation and Metabolism During Clipping of Ruptured Cerebral Aneurysm
Despite the theoretical benefits of i.v. agents, volatile agents remain popular. In a study comparing desflurane, isoflurane, and sevoflurane in a porcine model of intracranial hypertension, at equipotent doses and normocapnia…
- Trial name
- NCT03778723
- Testing
- Total intravenous anesthesia (TIVA), Inhalation Anesthesia, Rescue fentanyl
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Remimazolam, Desflurane
Remimazolam vs Desflurane for General Anesthesia for Ablation of Arrhythmia
In anesthesia for ablation for cardiac arrhythmias, abrupt hemodynamic changes or fatal arrhythmias can be seen frequently. Remimazolam is a novel ultra-short acting benzodiazepine that provides good hemodynamic stability…
- Conditions
- Remimazolam, Desflurane, Cryoablation, Arrhythmia
- Trial name
- NCT05486377
- Testing
- Remimazolam besylate
- Where
- South Korea
- Volunteers
- 96 people
- Sponsor
- Seoul National University Bundang Hospital
Hyperglycemia
Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins
Anesthetic preconditioning (APC, a brief exposure to an anesthetic gas) has become an area of intense research interest because of its ability to protect tissue and organs from injury resulting from a cessation of blood flow and…
- Trial name
- NCT00995670
- Testing
- 5% dextrose, Vitamin C, Simvastatin
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Video-assisted Thoracoscopic Surgery (VATS), Thoracic Surgery, Video Assisted
Target-Controlled Infusion (TCI) vs Inhalational Anesthesia in Video-Assisted Thoracoscopic Surgery (VATS)
This study is designed as a prospective observational cohort to evaluate recovery after video-assisted thoracoscopic surgery (VATS).
- Conditions
- Video-assisted Thoracoscopic Surgery (VATS), Thoracic Surgery, Video Assisted, Postoperative Recovery, General Anesthesia
- Trial name
- TCI-INHALE (NCT07288099)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul University - Cerrahpasa
Hysterectomy
Preoperative Oral Pregabalin Effect on Inhalational Anesthetic Requirements ln Hysterectomy Under General Anesthesia
In this study the investigators hypothesized that preoperative pregabalin tablet (150 mg orally ) may be effective in reducing intraoperative isoflurane requirements needed to maintain intraoperative hemodynamics within ± 20% of…
- Trial name
- NCT03302208
- Testing
- Pregabalin
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Nesrine El-Refai
Anesthesia Awareness
TIVA vs Inhalational Mode of Anaesthesia
Sevoflurane based inhalational anaesthesia is the preferred mode of anesthesia for small duration cases. But in recent times, concept of rapid discharge, day care procedures, and green environment has created the need of new…
- Trial name
- NCT03807297
- Testing
- Injection dexmedetomidine, Injection, Propofol, 10 Mg, sevoflurane
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Postoperative Cognitive Dysfunction
Early Postoperative Cognitive Dysfunction After Closed Loop Anesthesia vs Inhalational Anesthesia or TIVA
This study is designed to test the hypothesis that closed loop system reduces post operative cognitive dysfunction incidence 15 min after anesthesia more than desflurane, sevorane, total intravenous anesthesia manually guided by…
- Trial name
- NCT02656901
- Testing
- auto total endovenous anesthesia, Manual Desflurane anesthesia, Manual Sevoflurane anesthesia
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- University of Foggia
Acute Ischemic Stroke Patients
Prospective Randomized Observer Blinded Single Center Study Comparing 90-day Functional Outcome in Patients Who Received Intravenous Propofol Infusion Versus Inhalational Sevoflurane for General Anesthesia During Mechanical Thrombectomy in Patients Who Suffered From Acute Ischemic Stroke
This study is being done to compare outcomes after surgery for individuals who receive anesthesia through by inhaling medication and individuals who receive anesthesia intravenously by needle when experiencing treatment for their…
- Trial name
- NCT07001267
- Testing
- Anesthesia drugs during the surgery
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Kansas Medical Center
Alzheimer's Disease, Dementia
Inhalational Anesthesia and Precipitation of Dementia: is There a Link?
Many elderly patients undergoing surgical procedures already have impaired cognitive (memory/concentration) status. Patients with pre-existing cognitive impairment, or dementia, may benefit from modified anesthesia techniques.
- Trial name
- NCT01903421
- Testing
- Spinal anesthesia group: bupivacaine 10-15mg, General anesthesia group: induction propofol 1.5-2mg/kg and fentanyl 1-3g/kg, maintained with isoflurane or sevoflurane, Blood test
- Where
- 3 sites in Canada, Latvia
- Volunteers
- 500 people
- Sponsor
- University Health Network, Toronto
Neuromuscular Blockade, Anesthetic Agents
Effects of Anesthetics on High-Dose Rocuronium
This study evaluates the effects of three different anesthetics on high dose rocuronium in laparoscopic cholecystectomy cases. Patients were randomly assigned to one of the propofol, desflurane, or sevoflurane groups.
- Trial name
- NCT06045559
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Mustafa Kemal University
Delayed Recovery From Anesthesia
Automated Control of End-tidal Volatile Anesthetic Concentration
The new MIRUS system as well as the established AnaConDa system uses a reflector to conserve volatile anaesthetics (VA). Both systems act with commercially available ICU ventilators.
- Trial name
- MIRCONTROL (NCT02342509)
- Testing
- Desflurane, Sevoflurane, Isoflurane
- Volunteers
- 63 people
- Sponsor
- Ruhr University of Bochum
Heart; Dysfunction Postoperative, Cardiac Surgery, Disorder; Heart, Functional, Postoperative, Cardiac Surgery
Influence of Anesthesia on Mechanical Efficiency of Left Ventricle in Patients Undergoing Open Heart Surgery
The aim of the study is to delineate and compare the changes in coupled mechanical properties of left ventricle and arterial vascular bed caused by two popular anesthetic protocols commonly used in cardiac surgery (intravenous…
- Trial name
- NCT01397331
- Testing
- Isoflurane, Propofol
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Sheba Medical Center
Total Intravenous Anesthesia, Inhalational Anesthesia
Intravenous Anesthesia by Targeted Controlled Infusion Versus Inhalational Anesthesia on the Surgical Stress Response
This study aims to compare the effect of total Intravenous anesthesia Target-controlled infusion (TIVA-TCI) with inhalational anesthesia on stress response.
- Conditions
- Total Intravenous Anesthesia, Inhalational Anesthesia, Surgical Stress Response, Target-controlled Infusion
- Trial name
- NCT06024733
- Testing
- Sevoflurane, Target Controlled Infusion, Target Controlled Infusion and lidocaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Assiut University