Clinical trials: Inherited Erythromelalgia
Primary Erythromelalgia, Inherited Erythromelalgia
Study of XPF-001 in the Treatment of Pain From Primary/Inherited Erythromelalgia (IEM)
The purpose of this study is to determine whether XPF-001 is safe and effective in the treatment of pain caused by Inherited Erythromelalgia (IEM).
- Trial name
- NCT01090622
- Testing
- XPF-001
- Where
- Netherlands
- Volunteers
- 4 people
- Sponsor
- Xenon Pharmaceuticals Inc.
Erythromelalgia
Carbamazapine for Inherited Erythromelalgia Patients With NaV1.7 Mutations
This research study is designed to investigate brain response using fMRI scan, and behavioral responses, to treatment with the drug carbamazepine (CBZ) in patients with the painful sodium channelopathy inherited Erythromelalgia…
- Trial name
- NCT02214615
- Testing
- Carbamazepine
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- VA Connecticut Healthcare System
Inherited Erythromelalgia
Evaluation Of The Efficacy And Safety Of Single Doses Of PF-05089771 In Patients With Primary (Inherited) Erythromelalgia
The purpose of this study is to evaluate the efficacy and safety of single doses of PF-05089771 against placebo in treatment of pain in patients with primary, inherited erythromelalgia.
- Trial name
- IEM (NCT01769274)
- Testing
- PF-05089771
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Pfizer
Erythromelalgia, Pain Insensitivity, Congenital
Painful Channelopathies Study
To understand the pathophysiological basis of heritable pain syndromes. This will consist of a number of components: Determine the genetic basis for heritable pain syndromes.
- Conditions
- Erythromelalgia, Pain Insensitivity, Congenital, Hereditary Sensory and Autonomic Neuropathies, Chronic Pain
- Trial name
- PCS (NCT02696746)
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King's College London
Primary Erythromelalgia, Inherited Erythromelalgia
Phase 2a, Exploratory Study to Evaluate the Safety, Efficacy, Tolerability and Pharmacokinetics of XPF-002 in Patients With Primary/Inherited Erythromelalgia
This is a Phase 2a single-center, randomized, double-blind, Placebo-controlled, parallel group study with XPF-002 applied twice daily over 14 or 21 days in patients with Primary/Inherited Erythromelalgia (IEM).
- Trial name
- NCT01486446
- Testing
- XPF-002
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Xenon Pharmaceuticals Inc.
Familial Erythromelalgia
A Phase 1b Study of BHV-7000 in Participants With Inherited Erythromelalgia
The purpose of this study is to test the potential benefits of BHV-7000 in reducing chronic pain in participants with IEM with a previously demonstrated gain of function mutation in the SCN9A gene.
- Trial name
- NCT07262268
- Testing
- BHV-7000
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Biohaven Therapeutics Ltd.
Primary Inherited Erythromelalgia
A Phase 2a Study of BIIB074 in the Treatment of Erythromelalgia
The primary objective of the study is to investigate the efficacy of repeat oral dosing of BIIB074 on paroxysmal pain in participants with Primary Inherited Erythromelalgia (EM).
- Trial name
- NCT02917187
- Testing
- BIIB074
- Where
- 5 sites in United States
- Volunteers
- 8 people
- Sponsor
- Biogen