Clinical trials: Inhibition, Psychological
Adjustment Disorder With Work Inhibition
Neurobiological Effects of Work-related Adjustment Disorder
INTRODUCTION: Stress is one of the greatest burdens of our society and often imply impairments in cognitive and emotional functions.
- Trial name
- NeuroWAD (NCT03334045)
- Testing
- PET/MR scans
- Where
- Denmark
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Smoking Cessation
The Approach and Avoidance Task (AAT) in Smoking Cessation
The approach and avoidance task (AAT) has evolved as a promising treatment add-on in the realm of psychology. Certain psychiatric diseases, such as behavioural addictions, social anxiety disorder, and arachnophobia, are…
- Trial name
- NCT04190810
- Testing
- Inhibition, Classical AAT, Control
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Cervical Myofascial Pain Syndrome, Chronic Neck Pain
Type D Personality, and Stigma in Myofascial Pain Syndrome
Cervical myofascial pain syndrome is a chronic musculoskeletal condition characterized by the presence of sensitive trigger points and taut muscle bands, resulting in localized or referred pain, muscle stiffness, and limited…
- Conditions
- Cervical Myofascial Pain Syndrome, Chronic Neck Pain, Type D Personality, Psychological Distress
- Trial name
- NCT07292155
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Attention Deficit Disorder With Hyperactivity
Efficacy of the Apollo System for Children With ADHD
To determine the extent to which the Apollo System is effective in reducing symptomatology associated with ADHD.
- Trial name
- NCT05308706
- Testing
- 8 weeks of home based use.
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Michigan State University
Healthy Male Volunteers
Effects of Lacosamide on Human Motor Cortex Excitability: a Transcranial Magnetic Stimulation Study
This study has been designed to explore dose-depended effects of lacosamide (LCM) on motor cortex excitability with TMS in a randomized, double-blind, placebo-controlled crossover trial in young healthy human subjects, and to…
- Trial name
- NCT01382017
- Testing
- Lacosamide, Carbamazepine
- Where
- Germany
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Kiel
Multiple Sclerosis
Virtual Reality in Physical Therapy in Multiple Sclerosis
The randomized controlled trial is aimed to study the efficacy of virtual reality (VR) and its impact on upper limb function and postural stability in people with mild to severe multiple sclerosis (pwMS).
- Trial name
- VIREMS (NCT04807738)
- Testing
- Neuroproprioceptive "facilitation and inhibition" in virtual reality, Neuroproprioceptive "facilitation and inhibition"
- Where
- 2 sites in Czechia
- Volunteers
- 71 people
- Sponsor
- Charles University, Czech Republic
Binge Eating, Inhibition (Psychology)
Using Virtual Reality and Sensor Technology to Enhance Outcomes From Treatment for Binge Eating
This study evaluates whether virtual-reality-based inhibitory control trainings are more effective than computerized trainings in reducing binge eating symptomatology.
- Trial name
- NCT05041660
- Testing
- Virtual-reality-based training, Inhibitory Control Training, Computerized training
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Drexel University
Inhibition (Psychology), Updating
Attentional Control Training in Older Adults: Efficacy, Transfer and Brain Substrates
Formal education and cognitively stimulating hobbies and profession have a protective effect against age-related cognitive decline and Alzheimer's disease.
- Conditions
- Inhibition (Psychology), Updating, General Knowledge, No Training
- Trial name
- NCT03532113
- Testing
- Updating, Inhibition, General knowledge
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Binge Eating, Inhibition, Psychological
Transcranial Magnetic Stimulation and Inhibitory Control Training to Reduce Binge Eating: Brain and Behavioral Changes
People with BE are characterized by high impulsivity, high levels of craving for high-calorie foods, deficits in inhibitory control, and maladaptive decision making.
- Trial name
- BE-NEMOIC (NCT06649994)
- Testing
- Active iTBS of the DLPFC, Active iTBS of the vmPFC, Computerized inhibitory control training
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Raquel Vilar López
Neurophysiology, Physiology
Functional Implication of Corpus Callosum in Voluntary Strength in COPD Patients
Patients with COPD have lower capability of activating their muscles. At the cortical level, force production is not only controlled by contralateral primary motor cortex but also by ipsilateral motor cortex.
- Trial name
- NCT03807258
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- 2 sites in France
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- 5 Santé
Multiple Sclerosis
Neuroproprioceptive "Facilitation, Inhibition" and Brain Plasticity
This study investigates whether neuroproprioceptive "facilitation, inhibition" physical therapy induces plastic and adaptive processes of the CNS (white matter integrity changes), if they relate to clinical improvement, and…
- Trial name
- NEFAI (NCT04355663)
- Testing
- Motor program activating therapy, Vojta's reflex locomotion, Functional electric stimulation
- Volunteers
- 92 people
- Sponsor
- Charles University, Czech Republic
Social Anxiety
Virtual Reality Exposure for Socially Anxious Adolescents
Overall in this project, the primary goal is to evaluate the efficacy of virtual reality exposure (VRE) for adolescents with elevated social anxiety using a three-arm randomized controlled trial: (1) virtual reality exposure…
- Trial name
- VIRTUS (NCT06379633)
- Testing
- In vivo exposure, (Virtual reality) exposure
- Where
- Belgium
- Volunteers
- 120 people
- Sponsor
- KU Leuven
Lumbar Radicular Pain, Spinal
Cutaneous Silent Period-Based Comparison of DRG-PRF and TFESI in Lumbar Radicular Pain
This prospective clinical study compares the effects of two interventional treatments, dorsal root ganglion pulsed radiofrequency (DRG-PRF) and transforaminal epidural steroid injection (TFESI), on patients with lumbar radicular…
- Conditions
- Lumbar Radicular Pain, Spinal, Inhibition
- Trial name
- CSP-LRP (NCT07097532)
- Testing
- Radiofrequency, Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- ahmet başarı
Inhibitory Control, Self Efficacy
Differences Between Suicide Attempters and Suicide Ideators. Influence of the Brief Therapy Attempted Suicide Short Intervention Program (ASSIP) on Neuropsychological Correlates and Psychological Process Factors - Project 2
The present study consists of 3 projects in total and aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the effects and feasibility of ASSIP Home Treatment.
- Conditions
- Inhibitory Control, Self Efficacy, Suicide Ideation, Suicide, Attempted
- Trial name
- NePsyAssip HT (NCT06263712)
- Testing
- Attempted Suicide Short Intervention Program (ASSIP), Standard of care plus resource interview group (STAR)
- Where
- Switzerland
- Volunteers
- 156 people
- Sponsor
- University of Bern
Alcohol Use Disorder
Brain Connectivity Between Networks Implied in Inhibition and Cue-reactivity in Alcohol Use Disorder
Research about patients with alcohol use disorder has shown that task-related brain activation patterns as well as resting-state connectivity (measured with functional magnetic resonance imaging) change with clinical parameters…
- Trial name
- NIQA (NCT05843435)
- Testing
- Go-Nogo-task during functional magnetic resonance imaging, Resting-state functional magnetic resonance imaging
- Where
- Switzerland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Bern
Healthy
Brain Encoding for Memory
This two-part study will use transcranial magnetic stimulation, or TMS (see below), to explore how the brain forms memories. People remember only some of the events they experience every day, such as faces they perceive, words…
- Trial name
- NCT00051870
- Testing
- Magstim Rapid Magnetic Stimulator
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Postoperative Thromboembolism
Effect of Tumescent Lidocaine on Platelet Function
The purpose of this study is to evaluate the effect of lidocaine, delivered into subcutaneous tissue for tumescent local anesthesia, on platelet activation following the tumescent liposuction.
- Trial name
- NCT01463280
- Testing
- tumescent lidocaine infiltration
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Klein, Jeffrey A., M.D.
CBD, Fear
Effects of Cannabidiol (CBD) on the Brain
Cannabidiol (CBD) is a phytocannabinoid that is one of 113 identified cannabinoids in the cannabis plant. It is derived from the hemp plant, and may treat conditions like pain, insomnia, and anxiety.
- Conditions
- CBD, Fear, Inhibition
- Trial name
- CBD (NCT04831294)
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Auburn University
Optical Phenomena
Attention Modulation of Local and Global Inhibition Mechanisms
Human behavior is both flexible and adapted to the environmental context through inhibition capabilities; the investigator control the subject's behavior by repressing inappropriate responses and selecting, among several…
- Trial name
- MILGattention (NCT04279158)
- Testing
- experience 1 "The negative priming task", experience 2 "Stop signal task", experience 3 "Anti-saccades"
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Multiple Sclerosis
Nature of the Link Between Executive Functions and Theory of Mind in Multiple Sclerosis
The purpose of this study is to explore inhibition and inference abilities in The Theory of Mind skills in multiple sclerosis patients using the Theory of Mind task.
- Trial name
- TDE-SEP (NCT04806217)
- Testing
- Theory of Mind
- Volunteers
- 40 people
- Sponsor
- Lille Catholic University