Clinical trials: Injections
Healthy
Study of LY3074828 in Healthy Participants
The purpose of this study is to evaluate different concentrations and formulations of LY3074828 compared to placebo ("dummy drug"). The study will consist of 2 parts: Part A and Part B.
- Trial name
- NCT03748940
- Testing
- LY3074828, LY900021
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Chronic Hepatitis B Infection
A Phase I Clinical Study of AHB - 171 in Healthy Participants(HP) and Chronic Hepatitis B (CHB) Participants
The goal of this clinical trial is to evaluate the safety, tolerability, immunogenicity and Pharmacokinetics (PK) characteristics of AHB-171 Injection in healthy participants (Part A) and participants with chronic hepatitis B…
- Trial name
- NCT07511218
- Testing
- AHB-171 Injection, Nucleos(t)ide Analogue (NA)
- Where
- 2 sites in China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Ausper Biopharma Co., Ltd.
Moderate or Severe Submental Fullness
A Phase I Study of HY-2003 in the Subjects With Excessive Submental Fat Accumulation
The main purpose of this study is to evaluate the safety of HY-2003 in subjects with moderate to severe submental fat accumulation at different doses and dosing frequencies in comparison with the positive control and placebo.
- Trial name
- NCT06756490
- Where
- 2 sites in China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sichuan Huiyu Pharmaceutical Co., Ltd
Healthy
Pharmacokinetic/Pharmacodynamic Equivalence of MSB11455 in Healthy Subjects
The purpose of the study is to compare the pharmacokinetics (PK) and pharmacodynamics (PD) of MSB11455 and Neulasta in healthy adult subjects.
- Trial name
- NCT03251248
- Testing
- MSB11455, Neulasta
- Where
- 2 sites in Australia
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Fresenius Kabi SwissBioSim GmbH
Type 2 Diabetes, Overweight and Obesity
A Phase I Study of GZR18 Injection in Healthy Subjects
This trial is conducted in China. The aim of the trial is to evaluate the safety and tolerability of GZR18 injection in healthy subjects following single dose and once-weekly dose for 2 consecutive weeks until reaching the target…
- Trial name
- NCT06548997
- Testing
- GZR18
- Where
- China
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Gan and Lee Pharmaceuticals, USA
HIV Infections, HCV
A Setting Focus Overdose Prevention Intervention
A pilot injection-setting targeted peer-driven intervention to reduce HIV and hepatitis C virus transmission and overdose risk behaviors among people who inject drugs (PWID).
- Conditions
- HIV Infections, HCV, Drug Overdose
- Trial name
- Oasis (NCT05320835)
- Testing
- HIV, HCV and overdose prevention
- Where
- United States
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Vocal Cord Paralysis
Voice Rest and Injection Laryngoplasty
The purpose of this study is to evaluate the subjective, objective, and aerodynamic impact of voice rest following injection augmentation and compare the outcomes to patients with no post-procedure voice restrictions.
- Trial name
- NCT05542550
- Testing
- Voice Rest, No Voice Rest
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Pandemic Influenza Prevention
A Phase 4 Post-marketing Study of Intramuscular Injections of BLB-750 in Healthy Adult Subjects
The purpose of this study is to evaluate the immunogenicity and safety of two intramuscular vaccinations with BLB-750 in healthy Japanese adults.
- Trial name
- NCT03370289
- Testing
- BLB-750 Vaccine (Qinghai RG strain)
- Where
- Japan
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Takeda
Total Knee Arthroplasty
Peripheral Nerve Blocks vs Periarticular Local Anesthetic Injection for Total Knee Arthroplasty (TKA)
The purpose of this study is to find a better way to make patients comfortable after their knee surgery. The investigators compared three ways of providing pain relief, either by use of a nerve block at the femoral and sciatic…
- Trial name
- NCT02223364
- Testing
- Peripheral nerve blocks with Bupivacaine, Intra articular injection with Ropivacaine, Intra articular injection with liposomal bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Solid Tumor
Technetium [99mTc]-H7ND in Patients With Gastrointestinal Malignancies and Healthy Volunteers
The primary objective of this study is: to evaluate the safety of technetium [99mTc]-H7ND injection in patients with gastrointestinal malignancies and in healthy subjects.
- Trial name
- NCT06443710
- Testing
- Technetium [99mTc]-H7ND injection
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Jiaxing Pharmadax Genesis Pharmaceutical Technology Co.,Ltd.
Obesity, Weight Loss
Intra-gastric Fundal and Body Injection of Botulinum Toxin A for Weight Loss, a Randomized Controlled Trial
This is a randomized controlled trial to compare intra-gastric injection of Botulinum Toxin A (Botox; Allergan Inc. Irvine, Ca, USA) against non-surgical management for obesity (i.e. exercise/diet).
- Trial name
- NCT04274608
- Testing
- Botulinum toxin type A, Weight Management Program
- Where
- Singapore
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Energy, Fatigue
A Clinical Trial to Assess the Effects of a Vitamin Shot on Energy Levels
This is a virtual, single-arm clinical trial that will last 30 days. Participants will drink 1 bottle of the Vitamin Energy® shot daily and complete questionnaires at baseline, Day 7, Day 14, and Day 30.
- Conditions
- Energy, Fatigue, Mood, Weight Loss
- Trial name
- NCT06019858
- Testing
- Vitamin Energy Shot
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Vitamin Energy®
Infertility
Intracytoplasmic Sperm Injection Preparation in Infertile Women
Infertility is a common gynecological problem is women
- Trial name
- NCT03824340
- Testing
- Doxycycline before ICSI
- Where
- Egypt
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Alveolar Ridge Augmentation, Dental Implants
A Clinical Study of the Use of Brushite as Primary Stabilizer in Immediate Dental Implantation
Objective: The evaluation of "PD" VitalOs Cement, an injectable brushite, as a stabilizer of dental implants and a potential source for bone augmentation.
- Trial name
- NCT00299585
- Testing
- using "PD" VitalOs Cement with dental implants
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Healthy Volunteers
Tolerability & Pharmacokinetics of Ginkgolide B Injection: Single- and Multiple-Ascending Doses in Healthy Subjects
To evaluate the safety and tolerability of multiple intravenous infusions of Ginkgolide B Injection in healthy Chinese participants, as well as to assess the pharmacokinetic (PK) characteristics following single and multiple…
- Trial name
- NCT07457008
- Testing
- The 10mg dose group, The 20mg dose group, The 30mg dose group
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- West China Second University Hospital
NSCLC Associated With Leptomeningeal Metastases
Immune Checkpoint Inhibitors Intrathecal Injection in Patients With Leptomeningeal Metastases in NSCLC
This is a prospective, single-arm, open clinical study, which was designed to evaluate the efficacy and safety of an immune checkpoint inhibitor combined with pemetrexed intrathecal injection in the treatment of patients with…
- Trial name
- NCT06132698
- Testing
- Tislelizumab or pembrolizumab, pemetrexed
- Where
- China
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Influenza, Human
Jet Injection for Influenza
The purpose of this study is to determine if the administration of a seasonal flu vaccine using a PharmaJet's needle-free injection device (STRATIS) is equivalent to needle and syringe administration, as measured by laboratory…
- Trial name
- JIFI (NCT01688921)
- Testing
- AFLURIA vaccine (2012-2013 formulation), Needle-Syringe, Stratis needle-free injection device
- Where
- 3 sites in United States
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- PharmaJet, Inc.
Healthy Volunteers, Obesity
Phase 1 Clinical Study of MWN117 Injection in Healthy Participants and Participants With Obesity
This study is a randomized, double-blind, placebo-controlled, single-dose, dose-escalation Phase 1 clinical trial to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of MWN117 injection in healthy and…
- Trial name
- NCT07824804
- Testing
- MWN117
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Shanghai Minwei Biotechnology Co., Ltd
Healthy Subjects
A Study of Injection HB0017 in Adult Healthy Volunteers
placebo by subcutaneous (SC) administration. Forty subjects (10 subjects per cohort for SC administration) will be randomized and assigned to up to 4 sequential doses cohorts of HB0017 (50 mg, 150 mg, 300 mg and 450 mg) or…
- Trial name
- NCT04505033
- Testing
- HB0017
- Where
- New Zealand
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Huabo Biopharm Co., Ltd.
Pain
Low Dose Methoxyflurane and Out-Patient Aesthetic Surgery and Facial Filler
The aim of the study is to generate real-world evidence on the effectiveness, safety and additional parameters of low dose methoxyflurane (PENTHROX®) in: aesthetic surgeries (eg.
- Trial name
- NCT04292808
- Testing
- Methoxyflurane
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Verso Surgery Centre
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