Clinical trials: Injections
Aesthetic
Aesthetic Improvement of Facial Rhytids Using Injectables
Revanesse® Renew™+ (Prollenium Medical Technologies Inc.) is a non-crosslinked HA skin booster that combines low- and high-molecular-weight HA at a concentration of 14 mg/mL in a sterile aqueous gel for intradermal injection7.
- Trial name
- NCT07383766
- Testing
- Revanesse® Renew™+
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Erevna Innovations Inc.
Nerve Block, Hip Arthroscopy
Pain Control in Hip Arthroscopy: Comparing Lumbar Plexus Versus Peri-capsular Injection
Comparison of lumbar plexus nerve block versus pericapsular injection for pain control during hip arthroscopy
- Trial name
- NCT03244631
- Testing
- Lumbar Plexus BLock, Pericapsular injection
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Washington Orthopaedics and Sports Medicine
Local Anesthesia Infiltration
Efficacy of Facial Massager in Reducing Intra Oral Injection Pain in Pediatric Patients
Abstract Background: Local anesthesia is a primary source of anxiety in pediatric dentistry. Objective: To evaluate if mechanical vibration from a low-cost facial massager reduces pain and anxiety during injections using the Gate…
- Trial name
- NCT07682181
- Testing
- Facial T massager, Topical Benzocaine 20%
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Government Dental College and Hospital, India
Healthy
Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects
The purpose of this study is to assess the pharmacokinetics and pharmacodynamics of higenamine in healthy Chinese subjects
- Trial name
- NCT01451229
- Testing
- higenamine
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Normal Healthy Volunteers
Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Minocin (Minocycline) for Injection in Healthy Adults
This was a Phase 1, randomized, double-blind, placebo-controlled, single and multiple ascending dose study of the safety, tolerability, and pharmacokinetics of Minocin (minocycline) for injection in healthy adult participants.
- Trial name
- NCT02802631
- Testing
- Minocin (minocycline) for Injection
- Where
- Netherlands
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Rempex (a wholly owned subsidiary of Melinta Therapeutics, Inc.)
TMJ Disc Displacement With Reduction, TMD
ARS vs ARS With Arthrocentesis and PRP Injection in DDWR
This study will be conducted to assess the effect of anterior repositioning splint and arthrocentesis with platelet-rich plasma injection compared to anterior repositioning splint only, in TMD patients with anterior disc…
- Conditions
- TMJ Disc Displacement With Reduction, TMD, PRP Injection
- Trial name
- NCT07115797
- Testing
- arthrocentesis - PRP injection -ARS, ARS
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity
Endoscopic Ultrasound Guided Gastric Botulinum Toxin Injections Versus Glucagon Like Peptide 1 Receptor Agonist in Weight Loss
Background: Obesity is an important public health concern. Surgery is effective but invasive and expensive, and some obese persons are not good surgical candidates.
- Trial name
- NCT05268627
- Testing
- Liraglutide
- Where
- 2 sites in Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Alzheimer's Disease
A Study of Flortaucipir PET in Healthy Volunteers and Cognitively Impaired Subjects
This study will test if two flortaucipir PET scans up to 4 weeks apart in healthy volunteers, MCI and AD subjects provide the same results.
- Trial name
- NCT01992380
- Testing
- Flortaucipir F18, Brain PET scan
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Avid Radiopharmaceuticals
Hyperactive Masseter Muscle
Evaluation the Efficacy of Zinc on Botulinum Toxin A Injection
This clinical trial seeks to investigate a promising new approach to enhance the effectiveness and duration of Botulinum Toxin A (BTX-A) for the treatment of hyperactive masseter muscles.
- Trial name
- BTX-A (NCT07270042)
- Testing
- BOTOX 100U in normal saline with zinc
- Where
- Syria
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Latakia University
Osteoarthritis
Application of Injectable Platelet-Rich Fibrin for the Treatment of Temporomandibular Joint Osteoarthritis
The authors designed a randomized, controlled, double-blind clinical trial after the ethical approval by the University Ethics Committee.
- Trial name
- NCT04810923
- Testing
- i-PRF, Arthrocentesis
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Ege University
Dermal Filler, Rejuvenation
A Prospective Evaluation of Infraorbital Filler Injection
The goal of this clinical trial is to measure the facial volumetric changes over time in patients injected with hyaluronic acid dermal filler (Juvéderm Volbella XC) in the infraorbital (under eye) region.
- Trial name
- NCT05694286
- Testing
- Juvederm Volbella XC hyaluronic acid dermal filler injection
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Hyperlipidemias
Effects of Oral Glucose and Teduglutide on Plasma Lipoproteins
Some of the fat (triglyceride) from the food humans eat gets stored in the bowel. This triglyceride can then be released into the blood when another meal is consumed or in response to hormones.
- Trial name
- TED+GLC plasma (NCT03860688)
- Testing
- TED + glucose
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Cognition, Mental Fatigue
Investigation of Dietary Supplement Liquid Shot Products on Mental Energy, Cognition (Acuity),and Mood
This is a single center, randomized, double blind, placebo-controlled, crossover study to determine the acute effect of a developmental dietary supplement liquid shot product on cognitive task performance and perceived effect…
- Conditions
- Cognition, Mental Fatigue, Mood
- Trial name
- NCT06384586
- Testing
- Functional energy shot
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- The Water Street Collective
Anthrax
A Study of Anthrax Vaccines Px563L and RPA563 in Healthy Adult Subjects
The trial investigates Px563L and RPA563, two formulations of a novel anthrax vaccine.
- Trial name
- NCT02655549
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Pfenex, Inc
Pain
Low Dose Methoxyflurane and Out-Patient Aesthetic Surgery and Facial Filler
The aim of the study is to generate real-world evidence on the effectiveness, safety and additional parameters of low dose methoxyflurane (PENTHROX®) in: aesthetic surgeries (eg.
- Trial name
- NCT04292808
- Testing
- Methoxyflurane
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Verso Surgery Centre
Hypoglycemia
Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of G-Pen(TM) (Glucagon Injection) to Treat Severe Hypoglycemia
The purpose of this study is to demonstrate that G-Pen(TM) glucagon is comparable to Lilly Glucagon(TM) in terms of safety and efficacy, as a treatment for severe hypoglycemia, a complication of diabetes.
- Trial name
- NCT01972152
- Testing
- G-Pen(TM) 1 mg, Lilly Glucagon(TM) 1 mg, G-Pen(TM) 0.5 mg
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xeris Pharmaceuticals
Obesity
A Study of JNJ-64565111 After Single Subcutaneous Administration at Different Injection Sites in Otherwise Healthy Overweight/Obese Adult Participants and a Study of JNJ-6456511 in Otherwise Healthy Obese Adult Participants After Multiple Dose
The purpose of this study is to compare the relative bioavailability of JNJ-64565111 between subcutaneous (SC) administrations in the upper arm versus the abdomen, and between SC administrations in the thigh versus the abdomen in…
- Trial name
- NCT03586843
- Testing
- JNJ-64565111
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Influenza Infection
Phase 1/2 Study of TAK-850 Subcutaneous Injection in Healthy Adults
The purpose of this study is to evaluate the safety and immunogenicity of a single subcutaneous injection of TAK-850 as compared to intramuscular injection of TAK-850 in healthy Japanese adults
- Trial name
- NCT02313155
- Testing
- Subcutaneous injection of TAK-850, Intramuscular injection of TAK-850
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Takeda
Infertility
HbA1c in Intracytoplasmic Sperm Injection
ICSI has increased nowadays for treating cases of longstanding infertility . HbA1c has an important value in evaluating glucose level in blood
- Trial name
- NCT03731858
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Healthy
Single Rising Dose Study With Intravenous Infusion and Subcutaneous Injection of BI 1005273 in Healthy Male Volunteers.
To investigate the safety and tolerability of BI 1005273 in healthy male volunteers following intravenous (i.v.) infusion of single rising doses and subcutaneous (s.c.) injection.
- Trial name
- NCT01650155
- Testing
- BI 1005273 s.c., BI 1005273 i.v.
- Where
- Germany
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
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