Clinical trials: Injections
Postmenopausal Osteoporosis
Comparing of the Pharmacokinetic, Safety and Immunogenicity of HS-20090-2 Injection and Prolia® in Healthy Adults
A randomized, single-blind and parallel group study to compare the pharmacokinetic, safety and immunogenicity of HS-20090-2 60mg#1ml#and Prolia® in healthy adults.
- Trial name
- NCT04940845
- Testing
- HS-20090-2, Prolia
- Where
- China
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Shanghai Hansoh Biomedical Co., Ltd
Healthy
MK-6194 Site of Injection Study in Healthy Adult Participants (MK-6194-013)
The goal of this study is to learn what happens to MK-6194 in a healthy person's body when different injection sites are used. Researchers will compare what happens to MK-6194 in a healthy person's body when it is injected into…
- Trial name
- NCT06649877
- Testing
- MK-6194
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Injection Site Irritation, Fear of Pain
Virtual Reality, Ice Application and Self-injection and Self-test Fair, Pain and State Anxiety
AİM:The aim of this study is to control the fears and anxieties of Type 2 diabetics in insulin injection and blood glucose measurement with motivational videos and Ice applications to be applied with virtual reality glasses.
- Trial name
- NCT04436666
- Testing
- motivational video production through virtual reality glasses, Ice Application
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Inonu University
Rotator Cuff Tear Arthropathy
Does Botulinum A Toxin Help With Pain From Rotator Cuff Arthropathy?
Rotator cuff arthropathy is a cause of shoulder arthritis which is a common condition seen both in primary and secondary care. It is a painful condition, with significant disability.
- Trial name
- NCT02512536
- Testing
- Botulinum Toxin Type A
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Interdental Papilla Augmentation
Minimally Invasive Volume Augmentation of Papillae Around Implant Restorations With Hyaluronic Acid Injection
Open gingival embrasures, also called "black triangles", may occur after surgical intervention or tooth replacement by an implant. They are perceived as anaesthetic by most patients and causing functional and phonetic problems.
- Trial name
- NCT02536807
- Testing
- Hyaluronan
- Where
- Sweden
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Malmö University
Healthy
Medroxyprogesterone Acetate Injection 150 mg/1 mL in Postmenopausal Women
This study compared the rates and extents of medroxyprogesterone absorption from two medroxyprogesterone acetate injection formulations following single 150 mg intramuscular (IM) injections to healthy postmenopausal women.
- Trial name
- NCT00830414
- Testing
- medroxyprogesterone acetate
- Where
- Germany
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Overweight, Obesity
A Study to Learn How the Study Medicine Called PF-08653944 is Taken up Into the Blood in Adults With Overweight or Obesity
This study is being done to learn how the study medicine affects the body and how safe it is for people who take it. The researchers will look at a number of health tests, including blood tests such as calcitonin, amylase, and…
- Conditions
- Overweight, Obesity, Healthy
- Trial name
- NCT07400679
- Testing
- PF-08653944
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Pfizer
Effect of Drug
Emla Cream Versus Benzocaine on Analgesia
EMLA is proven to be better in achieving pain control as topical anesthesia than benzocaine at palatal mucosa. So this research is done to compare its effectiveness at buccal mucosa.
- Trial name
- NCT05060913
- Testing
- EMLA Cream, Benzocaine Gel
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Etomidate, Myoclonus
Median Effective Dose of Remifentanil for the Prevention of Myoclonus Induced by Etomidate Injection
Since its introduction in 1973, etomidate has been widely used in clinical anaesthesia, especially in haemodynamically unstable patients, as a new anaesthetic induction drug with the advantage of low circulatory and respiratory…
- Trial name
- NCT05754762
- Testing
- Remifentanil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Post Operative Pain, Anesthesia
Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties
Comparison of post-operative pain after total shoulder surgery. The Principle Investigator will be comparing Exparel single shot block to Interscalene catheter
- Conditions
- Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
- Trial name
- NCT05868330
- Testing
- Interscalene Catheter, Exparel Single Shot Interscalene Block
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Melinda Seering
Stroke
Umbilical Cord Derived Mesenchymal Stem Cells Treatment in Ischemic Stroke
The study aims at estimating the safety and efficacy of the intravenous injection of human umbilical cord mesenchymal stem cell(hUC-MSC) for patients suffering from ischemic stroke in recent 3 months.
- Trial name
- Recruiting (NCT02580019)
- Testing
- Human umbilical cord mesenchymal stem cells
- Where
- China
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Retinal Vein Occlusion
Combined Intravitreal Injection of Bevacizumab and Fasudil Versus Bevacizumab Alone for Macular Edema Secondary to Retinal Vein Occlusion in Previously Treated Patients
This study is aimed to compare the effect of combined intravitreal Bevacizumab and Fasudil injection with Bevacizumab only injection in patients with persistant macular edema secondary to ratinal vein occlusion.
- Trial name
- NCT03391219
- Testing
- injection bevacizumab, injection Combined Bevacizumab and Fasudil
- Where
- Iran
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Failed Mechanical Induction
Efficacy of Two Injection Techniques on Success Rate of Inferior Alveolar Nerve Anesthesia
Forty healthy patients with including criteria who failed to infra alveolar nerve block injection (without lip numbness) have been randomly divided into two groups on a random basis and have received Gow-Gates or another inferior…
- Trial name
- NCT02543619
- Testing
- Injection technique
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Knee Osteoarthritis
Autologous Micro-fragmented Adipose Tissue Injection for Knee Osteoarthritis
Knee osteoarthritis (OA) is characterized by loss of cartilage leading to instability, reduced range of motion, and functional limitations.
- Trial name
- NCT03788265
- Testing
- Lipogems
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Vaginal Laceration During Delivery
The PAIN (Pelvic Area Injection for Numbness) Study
Postpartum pain can interfere with patient's ability to care for themselves, and their newborn, and untreated pain is associated with risk of greater opioid use, postpartum depression, and development of persistent pain.
- Trial name
- PAIN (NCT05972681)
- Testing
- Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Temporomandibular Arthritis
Intra-articular Injection for the Relief of Temporomandibular Joint Pain
Which is more effective in the treatment of nonspecific temporomandibular osteoarthritis: platelet-rich plasma (PRP), hyaluronic acid, or triamcinolone acetonide?
- Trial name
- NCT07571265
- Testing
- platelet rich plasma and triamcinolone acetonide and hyaluronic acid and saline intra articular injection
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cairo University
Myofascial Pain Syndromes
Effect of Lidocaine and Ozone in Injection for Myofascial Pain
Myofascial pain syndrome (MPS) is a chronic soft tissue rheumatism characterized by tense, painful muscle bands, known as trigger points, located within the muscle or fascia.
- Trial name
- NCT06768281
- Testing
- Headache Impact Test-6 (HIT-6), Pittsburgh Sleep Quality Index (PSQI), Visual Analogue Score (VAS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yağmur Malkoc
Aspergillus Infections, Candida Infections
Phase I Clinical Trial for Comparison of Pharmacokinetic Characteristics of Vorico Injection 200mg(Voriconazole) and Vfend® IV 200mg for Single Dose Crossover Intravenous Infusion in Healthy Volunteers
Phase I Clinical Trial for Comparison of Pharmacokinetic Characteristics of Vorico Injection 200mg(Voriconazole) and Vfend® IV 200mg for Single Dose Crossover Intravenous Infusion in Healthy Volunteers
- Conditions
- Aspergillus Infections, Candida Infections, Fungal Infections
- Trial name
- NCT02631954
- Testing
- Vorico Injection 200mg(Voriconazole), Vfend®(Voriconazole) IV 200mg
- Where
- South Korea
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Embryo Implantation
Intramuscular Injection of Human Chorionic Gonadotropin in Frozen Embryo Transfer Cycles
This study is a randomized controlled clinical trial to compare the pregnancy outcomes of infertile women with frozen embryo transfer.
- Trial name
- NCT04855383
- Testing
- The effect of intramuscular injection of triple doses of human chorionic gonadotropin in frozen embryo transfer cycles
- Where
- Iran
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Healthy
Single-center Study Evaluating the Safety and Efficacy of Viscogel® as Adjuvant in Act-HIB® Vaccine
The purpose of this study is to show that ViscoGel® is safe when administrated alone and as an adjuvant together with Act-HIB® vaccine in healthy volunteers and to evaluate the quantitative and qualitative effect on the immune…
- Trial name
- VSG-2011-101 (NCT01578070)
- Testing
- 0.2μg Act-HIB®, ViscoGel® and 0.2μg Act-HIB®, ViscoGel® and 2μg Act-HIB®
- Where
- Sweden
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Viscogel AB
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