Clinical trials: Injections
Coronavirus Infection
The Study of "Gam-COVID-Vac" Vaccine Against COVID-19 With the Participation of Volunteers of 60 y.o and Older
The purpose of this study: to assess the safety, tolerability and immunogenicity of the drug "Gam-COVID-Vac", a solution for intramuscular injection, at various times after vaccination in volunteers over 60 years of age
- Trial name
- NCT04587219
- Testing
- Gam-COVID-Vac
- Where
- Russia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Hepatitis B
Proof Of Concept : Immunogenicity and Safety of hepB Injection in the Dermis Using VAX-ID
A proof of concept (POC) study will be conducted in 44 volunteers that have been fully vaccinated against hepatitis B in the past (at least 5 years ago) to assess the safety and immunogenicity of intradermal vaccination with…
- Trial name
- POC_VAX-ID (NCT02186977)
- Testing
- VAX-ID, 1.0 cc HBVAXPRO 10mcgr/ml (Sanofi Pasteur MSD), 0.1cc HBVAXPRO 40mcgr/ml (Sanofi Pasteur MSD)
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Novosanis NV
Moderate to Severe Convexity of Submental Fat, Safety
Safety Study of Deoxycholic Acid for the Reduction of Localized Subcutaneous Fat in the Submental Area in Subjects 65 to 75 Years of Age
The objectives of this study are to explore the safety and efficacy of subcutaneous injections of Deoxycholic Acid relative to placebo, in the submental area of participants who are 65 to 75 years old.
- Conditions
- Moderate to Severe Convexity of Submental Fat, Safety, Efficacy
- Trial name
- NCT02123134
- Testing
- ATX-101
- Where
- 6 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kythera Biopharmaceuticals
Healthy
Safety,Tolerability, and Pharmacokinetic of KPCXM18 for Injection
to assess the safety,Tolerability, and pharmacokinetic of KPCXM18 for injection in healthy subjects
- Trial name
- NCT04629287
- Testing
- KPCXM18
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Kunming Pharmaceuticals, Inc.
Volume Deficit in the Hand
Effectiveness and Safety of Restylane Lyft With Lidocaine in the Dorsal Hand
This is a randomized, evaluator-blind, split hand, multi-center study of the effectiveness and safety or Restylane Lyft with Lidocaine compared to no treatment for injection in the dorsal hand to correct volume deficits.
- Trial name
- NCT02650921
- Testing
- Restylane Lyft with Lidocaine
- Where
- 7 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Wrinkles
Wrinkle Injection With Autologous Platelet Rich Plasma Study
Wrinkles result from imperfect repair of the dermal layer resulting in loss of collagen commonly due to ageing, smoking and sun exposure.
- Trial name
- WIPES (NCT01078493)
- Testing
- MyCells® (injection of platelet rich plasma)
- Where
- Singapore
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novena Medical Center
Wrinkle
Micro-injections of Transparent Hyaluronic Acid Gel (Restylane® Silk) for Rejuvenation of the Aging Cheek
The objective of this study is to determine the efficacy and safety of Restylane® Silk microinjections when used in a grid-like injection pattern for the correction of fine lines to the cheeks.
- Trial name
- NCT03461198
- Testing
- Restylane® Silk
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Overweight, Obesity
A Study to Learn How the Study Medicine Called PF-08653945 is Taken up Into the Blood in Adults With Overweight or Obesity
This study is being done to learn how the study medicine affects the body. It will also assess how safe it is for people who take it. The researchers will use blood tests to measure how much medicine is in the blood.
- Conditions
- Overweight, Obesity, Healthy
- Trial name
- NCT07725809
- Testing
- PF-08653945
- Where
- Belgium
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Pfizer
Therapeutic Equivalency, Healthy
Bioequivalence Study of WP205 in Healthy Subjects
This study is a single-center, randomized, open-label, two-period, two-sequence, single-dose, crossover bioequivalence trial conducted under fasting conditions in healthy adult volunteers.
- Trial name
- NCT07158099
- Testing
- Methylconalamin Injection(WP205), Methylconalamin for Injection
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wanbangde Pharmaceutical Group Co., LTD
Infection
A Study To Assess The Safety, Tolerability And Pharmacokinetics Of Metronidazole Injection In Healthy Japanese Subjects
The purpose of this study is to assess the safety, tolerability and pharmacokinetics of metronidazole following single and multiple intravenous infusion in healthy Japanese adult subjects.
- Trial name
- NCT01407016
- Testing
- metronidazole IV 500 mg
- Where
- Japan
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pfizer
Aging
Effectiveness and Safety of STYLAGE® L Lidocaïne in the Treatment of Nasolabial Folds
STYLAGE® L Lidocaine is a CE-marked hyaluronic acid gel intended to fill skin depressions on the face by dermal injection. In this study, 50 healthy subjects between the age of 30 and 65, with moderate to severe nasolabial folds…
- Trial name
- NICE (NCT04844216)
- Testing
- STYLAGE® L Lidocaine, Active control
- Where
- 2 sites in France, Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Full-thickness Rotator Cuff Tear, Rotator Cuff Tendinitis
Effectiveness of Corticosteroid vs Ketorolac Shoulder Injections
The purpose of this study is to compare the functional outcomes of patients with shoulder pathology treated with either ketorolac or corticosteroid injections, in a randomized double-blinded study.
- Trial name
- NCT04895280
- Testing
- Ketorolac, Marcaine, Kenalog
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Michael Khazzam
Systemic Juvenile Idiopathic Arthritis, Periodic Fever Syndrome
Safety, Tolerability and Pharmacokinetic of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection
This study is Safety, Tolerability and Pharmacokinetic of Recombinant anti-IL-1β Humanized Monoclonal Antibody injection in Healthy Subjects.
- Trial name
- NCT05027373
- Testing
- SSGJ-613
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Cadmium Exposure
Safety Study of GMDTC Injection in Healthy Participants
This trial is a randomized, double-blind, single-center, single-dose escalating Phase I clinical trial designed to evaluate the safety, tolerability, and pharmacokinetic characteristics of injectable GMDTC in healthy subjects
- Trial name
- NCT05908383
- Testing
- GMDTC for injection, Normal saline
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd.
Heathy Volunteers
Bioequivalence Study Comparing Single Dose of Ferrinemia® Injection With a Single Dose of Venofer® Injection in Healthy Male Volunteers
The aim of this pharmacokinetic study is to assess the bioequivalence of the generic Ferrinemia® Iron Sucrose injection solution 20 mg/mL manufactured by Help S.A., Greece (test product), to Venofer® Iron Sucrose injection…
- Trial name
- NCT03093883
- Testing
- Ferrinemia, Venofer
- Where
- Austria
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Azad Pharma AG
Pain
Pharmacokinetic Study of Single and Multiple Intravenous Administration of Nalbuphine Hydrochloride Injection in Healthy Chinese Volunteers
Objective：To evaluate the pharmacokinetic characteristics and safety of single and multiple intravenous injections of nalbuphine hydrochloride injection in healthy subjects.
- Trial name
- NCT06902103
- Testing
- Nabufine Hydrochloride Injection
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd
Osteoarthritis (OA) of the Knee, Fear of Needles
Pain Perception During Intra-Articular Knee Joint Injection: What is the Effect of Needle Gauge and the Use of Ethyl Chloride?
This study aims to investigate factors that affect the subjective experience of pain during and after intra-articular knee joint injection of steroids by comparing needle gauge size (22 G vs 25 G needles), as well as the presence…
- Trial name
- NCT06865170
- Testing
- 25 gauge needle, 22 gauge needle, +/- Ethyl Chloride Topical Aerosol Anesthetic
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Nonalcoholic Steatohepatitis
A Trial to Evaluate the Safety Tolerability and Pharmacokinetics of B1344 by Subcutaneous Injection in Healthy Subjects
To evaluate the safety, tolerability, and immunogenicity of B1344 by single subcutaneous (s.c.) injection in healthy subjects
- Trial name
- NCT05655221
- Testing
- B1344
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tasly Biopharmaceuticals Co., Ltd.
Healthy
Study to Evaluate Pharmacokinetics, Safety and Efficacy of CM310
This is a single-center, randomized, open study to evaluate the pharmacokinetics, safety and immunogenicity CM310 in healthy subjects.
- Trial name
- NCT05702450
- Testing
- CM310
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Keymed Biosciences Co.Ltd
Contraception, Family Planning
Community Based Distribution of Injectable Contraceptives in Tigray, Ethiopia
The purpose of this study was to demonstrate that with appropriate training, the provision of injectable contraceptives by community based reproductive health agents (CBRHAs) does not significantly differ from low-level…
- Conditions
- Contraception, Family Planning, Task Shifting, Community Based Distribution
- Trial name
- CBDDMPA (NCT01288274)
- Testing
- Community Based administration of DMPA
- Where
- 3 sites in Ethiopia
- Volunteers
- 1,062 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
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