Clinical trials: Injections
Diabetes
Optimizing Insulin Absorption and Insulin Injection Technique in Older Adults
To determine which anatomic site offers the most consistent (superior) absorption of insulin. To determine the injection technique which allows the most consistent subcutaneous injection of insulin (to pinch or to spread).
- Trial name
- NCT01213901
- Testing
- Lispro insulin
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Contraception
Depo Provera Self-Administration Study: Putting a Patient-Centered Practice to the Test at Planned Parenthood
This randomized clinical trial will study subcutaneous depot medroxyprogesterone acetate (DMPA sc) self-administration at two Planned Parenthood affiliates serving diverse patient populations.
- Trial name
- DSAS (NCT02509767)
- Testing
- Subcutaneous depot medroxyprogesterone acetate
- Where
- 2 sites in United States
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood Federation of America
Schizophrenia Disorders
The Purpose of This Study is to Determine the Safety, Tolerability, and Pharmacokinetics of Brexpiprazole Long-acting Injection Following a Single Administration in Healthy Subjects/Patients With Schizophrenia.
Study to evaluate the safety and tolerability of single ascending doses of brexpiprazole long-acting injection in healthy subjects/patients with schizophrenia.
- Trial name
- NCT06674694
- Testing
- Brexpiprazole long-acting injection
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Sichuan Kelun Pharmaceutical Co.,Ltd.
Pain, Postoperative
Single and Double Injection Bilateral Thoracic Paravertebral Blocks in Reduction Mammaplasty
This study compares the analgesic effects and dermatomal blockade distributions of single and double injection bilateral thoracic paravertebral block (TPVB) techniques in patients undergoing reduction mammaplasty.
- Trial name
- NCT04517331
- Testing
- Thoracic paravertebral block-single injection, Thoracic paravertebral block-double injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Shoulder Pain
Pain Increases After Shoulder Injection
Compare FLARE reactions (increase in VAS by two or more points) in the first 48 hours following a shoulder injection.
- Trial name
- NCT05438277
- Testing
- Methylprednisolone (MPA), Triamcinolone Acetonide (TA)
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- Campbell Clinic
Failed Mechanical Induction
Efficacy of Two Injection Techniques on Success Rate of Inferior Alveolar Nerve Anesthesia
Forty healthy patients with including criteria who failed to infra alveolar nerve block injection (without lip numbness) have been randomly divided into two groups on a random basis and have received Gow-Gates or another inferior…
- Trial name
- NCT02543619
- Testing
- Injection technique
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azad University of Medical Sciences
Healthy
Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects
The purpose of this study is to assess the pharmacokinetics and pharmacodynamics of higenamine in healthy Chinese subjects
- Trial name
- NCT01451229
- Testing
- higenamine
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Respiratory Syncytial Virus Infections
Study of VN-0200 in Japanese Healthy Adults and Elderly Subjects
This study will assess the safety, tolerability, and immunogenicity of VN-0200 after intramuscular injections in Japanese healthy adults and elderly subjects.
- Trial name
- NCT04914520
- Testing
- VN-0200
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Daiichi Sankyo Co., Ltd.
Healthy
A Study to Evaluate Pharmacokinetics of Sonazoid™ Following Intravenous Bolus Injection in Healthy Volunteers
The primary purpose of this study is to determine the Pharmacokinetics (PK) data of perfluorobutane (PFB) in blood and exhaled air following intravenous (I.V.) bolus injection of Sonazoid™ in healthy volunteers.
- Trial name
- NCT03340870
- Testing
- Sonazoid™
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Asthma
Study of ARO-RAGE in Healthy Subjects
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of single- and multiple-ascending doses of ARO-RAGE Injection in normal healthy volunteers.
- Trial name
- NCT05533294
- Testing
- ARO-RAGE Injection
- Where
- New Zealand
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Arrowhead Pharmaceuticals
Cadmium Exposure
Safety Study of GMDTC Injection in Healthy Participants
This trial is a randomized, double-blind, single-center, single-dose escalating Phase I clinical trial designed to evaluate the safety, tolerability, and pharmacokinetic characteristics of injectable GMDTC in healthy subjects
- Trial name
- NCT05908383
- Testing
- GMDTC for injection, Normal saline
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Jianersheng (Zhuhai) Pharmaceutical Technology Co., Ltd.
Rotator Cuff Tear, Fatty Atrophy
Efficacy of an Amniotic Fluid Derived Allograft, (FlōGraft®) in Rotator Cuff Repairs: A Prospective Study
Rotator Cuff (RC) repair will be augmented with the injection of a human amniotic fluid derived allograft at the repair interface junction.
- Trial name
- NCT03379324
- Testing
- Superiority of augmented repairs, Fat degeneration of supraspinatus muscle
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Applied Biologics, LLC
HPV Seroconversion
Gardasil Immunogenicity With Needle-Free Injection
Using biospecimens collected in a trial by the Thai Red Cross AIDS Research Center that studied two new human papillomavirus (HPV) vaccine delivery regimens, the investigators at UCSF will be testing the serum for antibodies to…
- Trial name
- GINI (NCT01924754)
- Where
- 2 sites in United States, Thailand
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Painful Irreversible Pulpitis
Effect of Fentanyl on the Rate of Anesthesia
Achievement of a deep and long-durated anesthesia is vital before most endodontic procedures; therefore, the investigators conducted this study to compare the local infiltration effect of epinephrine-containing lidocaine with/…
- Trial name
- NCT01794533
- Testing
- Lidocaine with Epinephrine+ Normal saline, Lidocaine with Epinephrine + fentanyl
- Where
- Iran
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Diabetes Mellitus, Type 2
Single, Ascending Dose, First Time in Human Study for GZR18 in Healthy Subjects
Single ascending dose first time in human study for GZR18 in healthy subjects
- Trial name
- NCT05328726
- Testing
- GZR-18
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gan and Lee Pharmaceuticals, USA
Vaginal Delivery
Effect of Intravenous Hyoscine Butylbromide Injection on Labour in High Risk Women
A case control trial Patients who meet the inclusion criteria were asked to participate in the study and a written consent was obtained from each patient after explaining thoroughly the nature and the scope of the study.
- Trial name
- NCT03055390
- Testing
- hyoscine butylbromide
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Renal Colic
Diclofenac IM Versus Tramadol IV in Acute Renal Colic, RCT
Patients presented with acute pain from renal colic, the standard of care are prescribed NSAIDs, most common drug used is intramuscular (IM) Diclofenac injected at the gluteal muscle.
- Trial name
- NCT06231043
- Testing
- Diclofenac/Tramadol
- Where
- Thailand
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Lampang Hospital
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg
Onset Time of Nerve Block: A Comparison of Two Injection Locations in Patients Having Lower Leg/ Foot Surgery
The purpose of this study is to compare injecting local anesthetic (numbing medication) in different patterns around a major nerve in the leg.
- Conditions
- Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot
- Trial name
- NCT01542840
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Subcutaneous Fat
A Study to Evaluate the Efficacy and Safety of CBL-514 Injection for Reducing Subcutaneous Fat ( SUPREME-02 )
A phase 3, randomized, double-blinded, placebo-controlled study to evaluate the efficacy, safety, and tolerability of CBL-514 injection for reducing abdominal subcutaneous fat.
- Trial name
- NCT07526974
- Testing
- CBL-514 Injection, 0.9% Sodium Chloride
- Where
- 14 sites in United States, Australia and 1 more
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Caliway Biopharmaceuticals Co., Ltd.
HIV
Advancing Dignity, Health, and Optimism in Connection With Long Acting Injectables
ADHOC-LA is an observational study of people living with HIV who either are taking, or have taken, a long-acting injectable therapy to manage their HIV.
- Trial name
- ADHOC-LA (NCT05208541)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mazonson & Santas Inc.
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