Clinical trials: Injections
Anterior Cutaneous Nerve Entrapment Syndrome
Effect of Abdominal Wall Injections on Abdominal Pain
This is a prospective cohort study of outpatient adults with chronic abdominal wall pain receiving abdominal wall injections, as part of their usual care, with lidocaine.
- Trial name
- NCT06121466
- Testing
- Abdominal wall injections with lidocaine 2%
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Mental Disorders, Substance Use Disorders
Diagnostic Survey of Mental and Substance Use Disorders Among Norwegian College and University Students
The aims of this observational survey are to 1) collect data on the prevalence of mental and substance use disorders, and 2) investigate risk factors and consequences of mental and substance use disorder
- Conditions
- Mental Disorders, Substance Use Disorders, Treatment, Participation
- Trial name
- NCT05731102
- Testing
- Electronic version of the Composite International Diagnostic Interview 5th version (E-CIDI 5.0)
- Where
- Norway
- Volunteers
- 9,585 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Lower Back Pain, Facet Joint Pain; Low Back Pain
Bone Enhanced Ultrasound (BEUS) Data Library Development Project
A common treatment for low back pain involves fluoroscopy-guided spinal facet joint injections and/or medial branch nerve blocks.
- Conditions
- Lower Back Pain, Facet Joint Pain; Low Back Pain, Osteoarthritis (OA)
- Trial name
- NCT07036653
- Testing
- spinal ultrasound
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Queen's University
Hepatitis C, Opioid Use Disorder
Rural New England Health Study (Phase 2)
This study will integrate mobile hepatitis C virus (HCV) testing and treatment with expanded syringe access in order to improve uptake of HCV testing and treatment, and reduce syringe sharing behavior in rural northern New…
- Conditions
- Hepatitis C, Opioid Use Disorder, IV Drug Usage
- Trial name
- DISCERNNE (NCT05466331)
- Testing
- Mobile Tele-HCV Care, Enhanced Usual Care
- Where
- 3 sites in United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
Smallpox, Cowpox
Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BSY001 After Single/Multiple Doses.
A Two-Phase, Randomized, Double-Blind, Placebo-Controlled Phase I Clinical Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BSY001 for Injection Following Single or Multiple Doses in Healthy Subjects
- Conditions
- Smallpox, Cowpox, Monkeypox, Poxvirus Infection
- Trial name
- NCT07377175
- Testing
- BSY001 for Injection (37.5mg), BSY001 for Injection (75 mg), BSY001 for Injection (150 mg)
- Where
- China
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- China National Biotec Group Company Limited
Unilateral Cleft Lip
Philtrum Reconstruction Using Autogenous Fat Injection Versus a Surgical Repair in Secondary Unilateral Cleft Lip Revision
Two groups of patients with repaired unilateral cleft lip deformity having mild to moderate grooving and/or scarring of the philtral column and requiring a secondary cleft lip repair.
- Trial name
- NCT04735237
- Testing
- Autogenous fat injection, Surgical revision with orbicularis oris muscle reconstruction.
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hysterectomy, Surgery
IS-001 Injection Phase-1 Safety, Tolerance and Pharmacokinetics
A Phase 1 Open Label Single Center Safety, Tolerability and Pharmacokinetic Study of IS-001
- Trial name
- NCT03006237
- Testing
- IS-001, da Vinci® Si/Xi Surgical System
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Intuitive Surgical
Trismus, Edema
Management of Postoperative Complications After Mandibular Third Molar Extraction Using Submucosal Triamcinolone Injection, Kinesiology Taping, and Standard Care
The surgical removal of impacted lower wisdom teeth (mandibular third molars) frequently leads to uncomfortable postoperative symptoms, including pain, facial swelling (edema), and restricted jaw movement (trismus).
- Conditions
- Trismus, Edema, Pain
- Trial name
- NCT07719270
- Testing
- Triamcinolone Acetonide 10mg, Kinesiology Taping, Standard Postoperative Care
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Allama Iqbal Medical College
Pregnancy, Ovarian Hyperstimulation Syndrome
The Effect of a Dual Trigger on Intracytoplasmic Sperm Injection (ICSI) Reproductive Outcomes
The use of antagonist controlled ovarian stimulation protocols has allowed the use of GnRH agonist to be used for final oocyte maturation.
- Trial name
- NCT01979341
- Testing
- final oocyte maturation trigger
- Where
- Turkey (Türkiye)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Antalya IVF
Autoimmune Disease
A Study of Safety, Tolerability, PK, and PD of Subcutaneous GenSci136 in Healthy Adults.
This study is designed to evaluate the safety, tolerability, PK and PD of GenSci136 in a randomized, double-blind, placebo-controlled trial involving healthy adult participants.
- Trial name
- NCT07366866
- Testing
- GenSci136
- Where
- China
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Gingival Recession
Clinical Evaluation of Injectable Platelet Rich Fibrin With Connective Tissue Graft for the Treatment of Deep Gingival Recession Defects.
Aim: The aim of this study was to determine whether the combined connective tissue graft (CTG) with injectable platelet rich fibrin (i-prf) with coronally advanced flap (CAF) improved root coverage of deep Miller Class I or II…
- Trial name
- NCT04032405
- Testing
- CAF+CTG+i-prf
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Hyperuricemia
Tolerance, Pharmacokinetics / Pharmacodynamics (PK / PD) and Immunogenicity of Pegylated Uric Acid Oxidase for Injection in Healthy Adults and Hyperuricemia Volunteers
A randomized, double-blind, placebo-controlled study of tolerance, pharmacokinetic / pharmacodynamics (PK / PD) and immunogenicity of single administration of PEG uric oxidase for injection in healthy adults and hyperuricemia…
- Trial name
- NCT05226013
- Testing
- Polyglycol lated urate oxidase for injection
- Where
- China
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Adhesive Capsulitis, Frozen Shoulder
Adhesive Capsulitis: Prospective Analysis of Efficacy and Financial Impact for Use of Physical Therapy in Treatment
The purpose of this study is to identify individuals 18 or older who have diagnostic presentation of adhesive capsulitis and randomize them into two arms, distinguished by use of physical therapy and steroid injections compared…
- Conditions
- Adhesive Capsulitis, Frozen Shoulder, Shoulder Frozen
- Trial name
- NCT02283996
- Testing
- Physical Therapy, Depot Methylprednisolone
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pharmacokinetic Bioequivalence Study in Human Healthy Volunteers
Comparative, Pharmacokinetic and Pharmacodynamic Study of Subcutaneous Injections of INTP5 of Intas Pharmaceuticals Ltd., India Against Neulasta of Amgen Inc., USA in Healthy, Adult Human Subjects.
The study was an assessor-blind, balanced, randomized, two-treatment, two-period, single-dose, two-way crossover, comparative, pharmacokinetic (PK) and pharmacodynamic (PD) study of subcutaneous (SC) Pegfilgrastim injection (6…
- Trial name
- NCT04014062
- Testing
- INTP5, US Neulasta
- Where
- India
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Intas Pharmaceuticals, Ltd.
Dermal Fillers, Cheek Augmentation
Evaluation of Performance and Safety of Injectable KIO017 Device Range for Facial Tissue Filling
The goal of this clinical trial is to primarily evaluate the performance of KIO017 in filling/volumizing after injection in different areas in healthy women or men, older than 18 years and seeking an improvement of her/his face…
- Conditions
- Dermal Fillers, Cheek Augmentation, Lip Augmentation, Perioral Rhytids
- Trial name
- LITCHEE (NCT06872359)
- Testing
- KIO017-1, KIO017-2, KIO017-3
- Where
- 3 sites in France, Poland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kiomed Pharma
Healthy Subjects
Incretin and KATP Channels
This study aims to examine the involvement of KATP channels on the microvascular actions of the incretin GLP-1 and its analogues in healthy individuals and to determine whether the acute oral administration of different KATP…
- Trial name
- NCT01934816
- Testing
- Intradermal injections of GLP-1 and its analogues
- Where
- United Kingdom
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Katarina Kos
Age Related Macular Degeneration
Comparison of Treatment Response to Intravitreal Injection of Combined Propranolol and Bevacizumab Versus Bevacizumab Monotherapy in Patients With Wet Age Related Macular Degeneration :A Clinical Trial
This study is designed to compare the effect of combined intravitreal Bevacizumab and Propranolol injection versus Bevacizumab monotherapy in patients with Age Related Macular Degeneration.
- Trial name
- NCT03609307
- Testing
- Combined Intravitreal bevacizumab and propranolol, Intravitreal bevacizumab
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Dermal Fillers
Pivotal Study to Evaluate the Efficacy and Safety of Injection With LASBEAU Strong in Correction of Nasolabial Folds
Background: Nonsurgical injectable treatments have become popular for aesthetic purposes. In recent years, cross-linked hyaluronic acid (HA) fillers containing lidocaine have been used to correct the nasolabial folds.
- Trial name
- NCT06310863
- Testing
- LASBEAU Strong or Restylane Lyft injection as hyaluronic acid fillers
- Where
- South Korea
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Moderate to Severe Convexity of Submental Fat, Safety
Safety Study of ATX-101 (Deoxycholic Acid) in Subjects With Mild or Extreme Fullness of Submental Fat
The objectives of this study are to explore the safety and efficacy of subcutaneous injections of Deoxycholic Acid relative to placebo, in the submental area in patients with mild or extreme fullness of the submental fat and…
- Conditions
- Moderate to Severe Convexity of Submental Fat, Safety, Efficacy
- Trial name
- NCT02035267
- Testing
- Deoxycholic Acid
- Where
- 8 sites in United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Kythera Biopharmaceuticals
Obesity
Outcome of Combined Botulinum Toxin A Injection and Gastric Balloon Implantation in Obesity Treatment
Obesity, which is defined as the accumulation of fat in the body to a degree that impairs health, is defined as a serious public health problem and it is estimated that 13% (approximately 650 million) of the entire world…
- Trial name
- NCT05872932
- Testing
- gastric balloon implantation, botulinum toxin A injection
- Where
- Turkey (Türkiye)
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Sebahattin Celik MD
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