Clinical trials: Injections
Local Anesthesia Injection Pain
Effectiveness of Laser Photobiomodulation Therapy in Reducing Child Pain During Local Anesthesia Injection
This study aimed to evaluate the impact of laser photobiomodulation therapy used as pre-anesthetic technique to reduce child pain during local anesthesia administration
- Trial name
- NCT05861154
- Testing
- Photobiomodulation, Benzocaine Gel
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Aliaa Hamouda
Pain, Acute, Fear Anxiety
The Effect of Helfer Skin Tap Technique on Pain, Fear, and Anxiety in Children Undergoing Intramuscular Injection
The aim of this study was to examine the effect of the Helfer Skin Tapping technique on pain, fear, and anxiety in children who received intramuscular injections.
- Conditions
- Pain, Acute, Fear Anxiety, Child, Only, Injection Site
- Trial name
- NCT05250804
- Testing
- Helfer Skin Tap Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Aylin Kurt
Chronic Low Back Pain, Sacroiliitis
Effectiveness of Ultrasound Guided Platelet Rich Plasma Injections in the Sacroiliac Joint
This prospective study will be quantitatively analyzing the effectiveness of platelet-rich-plasma (PRP) injections into the sacroiliac (SI) joint in relieving sacroiliitis and low back pain originating from the SI joint.
- Conditions
- Chronic Low Back Pain, Sacroiliitis, Sacroiliac; Backache, Platelet Rich Plasma
- Trial name
- NCT03122119
- Testing
- Platelet Rich Plasma Joint Injection
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Star Spine and Sport
Diabete Type 2, Cataract
Corticosteroid Injection Combined With Cataract Surgery in Diabetic Eyes.
The investigators aim in this study to investigate the effect of intravitreal triamcinolone acetonide injection on the development of macular edema and the progression of diabetic retinopathy.
- Conditions
- Diabete Type 2, Cataract, Triamcinolone Acetonide, Intravitreal Injection
- Trial name
- NCT05413330
- Testing
- Triamcinolone Acetonide
- Where
- Syria
- Volunteers
- 73 people
- Sponsor
- Damascus University
Intravitreal Injection, Ocular Rinse
The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections
This is the first randomized controlled trial looking into post-injection rinse volume of standard ophthalmic eyewash and its affect on patient comfort up to 72 hours after injections.
- Conditions
- Intravitreal Injection, Ocular Rinse, Age-Related Macular Degeneration, Diabetic Macular Edema
- Trial name
- NCT05615805
- Testing
- OSDI questionnaire, SPEEDII questionnaire
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Age-related Macular Degeneration, Diabetic Macular Edema
Topical Proparacaine Eye Drops to Improve the Experience of Patients Undergoing Intravitreal Injections
The specific aims of this study are to compare patient experience with and without a proparacaine drop after povidone iodine.
- Conditions
- Age-related Macular Degeneration, Diabetic Macular Edema, Injection Site, Injection Site Infection
- Trial name
- NCT02951351
- Testing
- Proparacaine, Conjunctival culture
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Injection, Blood Glucose, High
Application of Needle-free Injection of Insulin in Patients With Gestational Diabetes Mellitus
This study is about the application of needle-free injection device in GDM patients in order to observe the variation of blood glucose and patients' experience compared to the traditional insulin pen injection.
- Conditions
- Injection, Blood Glucose, High, Glycemic Control, Gestational Diabetes
- Trial name
- NCT05394727
- Testing
- Needle-free injection device, Then traditional insulin pen, Traditional insulin pen , Then Needle-free injection device
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Injection Site Bruising, Bruising
Cold Application on the Subcutaneous Injection
The goal of this clinical trial is to compare the effect of cold application at different periods of time on the occurrence of bruising, haematoma and pain in the subcutaneous low molecular weight heparin (LMWH) injected patients.
- Conditions
- Injection Site Bruising, Bruising, Pain
- Trial name
- NCT05771285
- Testing
- Cold application
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Yuksek Ihtisas University
Injections, Pain
Effectiveness of Two Different Methods During Intramuscular Antibiotic Injection: ShotBlocker, Local Vibration
In intramuscular injection applications, which are among the responsibilities and basic skills of nurses, different methods are used to reduce the pain caused by injection and increase the individual's satisfaction.
- Conditions
- Injections, Pain, Satisfaction, Patient
- Trial name
- NCT04851158
- Testing
- Effectiveness of ShotBlocker on the perceived pain and satisfaction during intramuscular antibiotic injection, Effectiveness of local vibrator device on the perceived pain and satisfaction during intramuscular antibiotic injection
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Istanbul Medeniyet University
Intramuscular Injection, Pain
The Effect of Helfer Skin Tap Technique During Tetanus Injection in Pregnant Women
Intramuscular (IM) vaccination administered using the right injection technique is known to cause less pain and injury. Nurses employ different approaches like applying pressure, tapping the skin, cold and hot applications for…
- Trial name
- NCT05761340
- Testing
- Helfer skin tap injection technique, Standard Injection technique
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Intracytoplasmic Sperm Injection, Infertility, Male
Outcome of Using Sperm Bound to the Zona Pellucida of Immature Oocytes for Intracytoplasmic Sperm Injection (ICSI)
In vivo, the zona pellucida (ZP) of the oocyte can bind to normally functional sperm. The ZP-sperm interaction is one of the final steps of natural selection during their journey in the female reproductive tract.
- Trial name
- NCT05724979
- Testing
- ZP-binding
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Needle Phobia, Needle Fear
Determining Whether There is a Change in Time Taken to Return to Homeostatic Temperature With Repeated Exposure to a Cold Stressor
There has been previous research suggesting cold has an effect on pain relief, however there is limited knowledge on the relationship between exposure time of a cold stressor and how long it takes to return to homeostatic…
- Conditions
- Needle Phobia, Needle Fear, Injection Fear
- Trial name
- NCT05713539
- Testing
- Metal block
- Where
- United Kingdom
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- The Whiteley Clinic
Injections, Spinal, Cancer
Place of Intrathecal Analgesia to Improve the Quality of Life of Painful Cancer Patients
The intrathecal analgesia is a recommended technic to treat persistent pain in cancer patient but little used, whose the technical conditions require hospital multidisciplinary expertise and coordination associated to a link…
- Trial name
- QUALITHEC01 (NCT04388449)
- Where
- 3 sites in France
- Volunteers
- 24 people
- Sponsor
- Institut Cancerologie de l'Ouest
Diabetes Mellitus, Type 2, Insulin Injection Pad
Video Training to Reduce Insulin Administration Errors
Efficiency of training with video to reduce injection errors in patients using insulin
- Conditions
- Diabetes Mellitus, Type 2, Insulin Injection Pad, Injection Site, Insulin Implementation Errors
- Trial name
- NCT05658744
- Testing
- Video group
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Injection Site Irritation, Fear of Pain
Virtual Reality, Ice Application and Self-injection and Self-test Fair, Pain and State Anxiety
AİM:The aim of this study is to control the fears and anxieties of Type 2 diabetics in insulin injection and blood glucose measurement with motivational videos and Ice applications to be applied with virtual reality glasses.
- Trial name
- NCT04436666
- Testing
- motivational video production through virtual reality glasses, Ice Application
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Inonu University
Frozen Shoulder, Hydrodilatation
The Effect of Combined Hydrodilatation, Corticosteroid Injection, and Joint Mobilization for Treament of Frozen Shoulder
The effect of combination of hydrodilatation, corticosteroid injection, and joint mobilization for treatment of frozen shoulder, compared with general physical therapy.
- Conditions
- Frozen Shoulder, Hydrodilatation, Joint Mobilization, Corticosteroid Injection
- Trial name
- NCT04474145
- Testing
- Comb group, PT group
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
ASOCT Changes After Vitrectomy and Silicone Oil Injection
Short-term Anterior Segment Changes After Pars Plana Vitrectomy (PPV) and Silicone Oil (SO) Tamponade, Anterior Segment OCT (AS-OCT) Study.
The purpose of our study is to utilize AS-OCT to analyze the anterior segment morphological changes in the early postoperative period of patients who will undergo PPV with silicone oil injection.
- Trial name
- NCT05599854
- Testing
- vitrectomy and silicone oil injection
- Volunteers
- 30 people
- Sponsor
- Assiut University
Osteo Arthritis Knee, Injection Site Discomfort
Vapocoolant Spray Application During Intraarticular Knee Injection
The goal of this observational study is to learn about the effects of vapocoolant spray applied during intraarticular knee injections on pain and anxiety compared to injections without any agent application in patients with knee…
- Conditions
- Osteo Arthritis Knee, Injection Site Discomfort, Injection Fear
- Trial name
- NCT05581433
- Testing
- Topical Cooling Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Istanbul Rumeli University
Injection Site Irritation
Valsalva Manoeuvre and Intravenous Dexmedetomidine on Attenuating Pain During Propofol Injection in Upper GIT Endoscopy
No previous study has cited the use of the Valsalva manoeuvre for the reduction of pain on propofol injection in comparison with dexmedetomidine injection.
- Trial name
- Valsalva (NCT05225610)
- Testing
- Valsalva Manoeuvre, Dexmedetomidine Injection [Precedex], normal Saline
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tanta University
Expectations, Back Pain
Can Patient Expectations Influence Pain Reduction After Epidural Injections in Patients With Low Back Pain?
Investigators hypothesize that patients with higher expectations regarding their epidural injection experience a higher pain reduction of their lower back pain and/or leg pain after an epidural injection.
- Conditions
- Expectations, Back Pain, Back Pain Lower Back Chronic, Satisfaction, Patient
- Trial name
- NCT05402631
- Testing
- Epidural Injection, Periradicular Injection
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Ospedale Regionale di Lugano