Clinical trials: Injections
Cardiac Surgery, Postoperative Pain
Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block for Cardiac Surgery
This prospective, randomized, controlled study aims to evaluate the effects of ultrasound-guided bilateral single-shot serratus posterior superior intercostal plane (SPSIP) block on postoperative recovery and pain management in…
- Conditions
- Cardiac Surgery, Postoperative Pain, Postoperative Recovery After Cardiac Surgery
- Trial name
- NCT07785323
- Testing
- Serratus posterior superior intercostal plane block, Standard Perioperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Burak Çilingir
Multiple Sclerosis
Herbal Therapy for Subcutaneous Injection Site Reactions in Multiple Sclerosis
The purpose of this study is to determine if an herbal over-the-counter cream can decrease skin site reactions in multiple sclerosis patients who currently take either Betaseron, Copaxone or Rebif as their subcutaneous medication…
- Trial name
- MSSkin (NCT00972062)
- Testing
- Bach's Rescue Remedy Cream
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of North Carolina, Charlotte
Anesthetics, Inhalation
50% Effective Concentration of Sevoflurane for Immobility
Sevoflurane is as attractive inhalation agent fore deep sedation in children undergoing short invasive procedure because of lack of irritation to the respiratory tract, a pleasant odor and rapid clinical effect and recovery due…
- Trial name
- NCT03553446
- Testing
- children receiving sevoflurane
- Where
- South Korea
- Volunteers
- 23 people
- Sponsor
- Yeungnam University College of Medicine
Cancer of Skin, Solid Tumors
Peritumoral Injection of Immature Dendritic Cells to Irradiated Skin Metastases of Solid Tumors
Melanoma is the main cause of death in patients with skin cancer. Once it has metastasized, this cancer has been shown to respond to chemotherapy only in rare cases.
- Trial name
- NCT00278018
- Testing
- Immunotherapy treatment for solid tumors
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Hadassah Medical Organization
Multiple Sclerosis
An Open-Label, Single-Arm Clinical Study to Evaluate the Safety and Preliminary Efficacy of CD20 Monoclonal Antibody Combined With NK042 Cell Injection in the Treatment of Multiple Sclerosis (MS).
This is an Open-Label, Single-Arm Clinical Study to Evaluate the Safety and Preliminary Efficacy of CD20 Monoclonal Antibody Combined with NK042 Cell Injection in the Treatment of Multiple Sclerosis (MS).
- Trial name
- NCT07546110
- Testing
- NK042, ofatumumab
- Volunteers
- 20 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Focus: Bioavailability
Characterization of Cyanocobalamin in Healthy Voluteers After Intranasal and Intramuscual Administration
The main purpose of this study is to assess the relative bioavailability of Nascobal Nasal Spray as compared to an IM injection of cyanocobalamin (European reference product).
- Trial name
- NCT01306123
- Testing
- Nascobal nasal spray (cyanocobalamin, USP), Vitamin B12-ratiopharm N, injection solution
- Where
- Sweden
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Swedish Orphan Biovitrum
Vocal Fold Sulcus ,Scar and Atrophy
Vocal Fold Injection by Platelet Rich Plasma
a study to asses safety and efficacy of platelet rich plasma injection in some types of vocal fold problems such as sulcus and atrophy to see the improvement in patient voice and its impact on patient quality of life with a good…
- Trial name
- NCT07350642
- Testing
- injection of platelet rich plasma, Nasofiberoscopy
- Where
- 2 sites in Egypt
- Volunteers
- 48 people
- Sponsor
- Assiut University
Metastatic Prostate Cancer
Real-world Use of Lutetium (177Lu) Vipivotide Tetraxetan in China(PSMAreal CN)
This non-interventional, observational, multicenter, prospective cohort study is designed to investigate the treatment patterns of mPC patients treated with lutetium (177Lu) vipivotide tetraxetan, as well as their clinical…
- Trial name
- PSMAreal (NCT07290270)
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Novartis Pharmaceuticals
Postoperative Cognitive Dysfunction in Patients With Aneurysmal Subarachnoid Hemorrhage
The Effect of Huperzine A Injection on Postoperative Cognitive Dysfunction in Patients With Aneurysmal Subarachnoid Hemorrhage: a Pilot Study
Under the premise of basic treatment, to explore the improvement effect of huperzine A injection on short-term and long-term neurocognitive dysfunction in patients with aneurysmal subarachnoid hemorrhage after…
- Trial name
- NCT05560373
- Testing
- Huperzine A injection, operational treatment, the best basic treatment, operational treatment, the best basic treatment, Huperzine A injection, interventional treatment, the best basic treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wanbangde Pharmaceutical Group Co., LTD
Degenerative Joint Disease
Platelet-Rich Plasma vs Corticosteroid Injection as Treatment for Degenerative Pathology of the Temporomandibular Joint
1.0 BACKGROUND AND HYPOTHESES 1.1 Osteoarthritis is a continuous and entirely physiologic adaptive process that occurs in every joint.
- Trial name
- NCT01920373
- Testing
- Group A (corticosteroid injection group), Group B (platelet rich plasma injection group)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Proliferative Diabetic Retinopathy
Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy
The purpose of this study was to evaluate the efficacy and safety of brolucizumab compared to panretinal photocoagulation laser (PRP) in patients with proliferative diabetic retinopathy (PDR).
- Trial name
- CONDOR (NCT04278417)
- Testing
- Brolucizumab 6 mg, Panretinal photocoagulation laser
- Where
- 120 sites in United States, Argentina and 14 more
- Volunteers
- 689 people
- Sponsor
- Novartis Pharmaceuticals
Molar Hypomineralization
Intraosseus Injection Using Extra-short Needle Combined With Infiltration in Pediatric Patients With Molar Incisor Hypomineralization
Background: Effective pain control is crucial in managing pediatric dental patients. Molar-incisor hypomineralization (MIH), marked by enamel defects and dentin hypersensitivity, often hinders effective local anesthesia.
- Trial name
- NCT07239050
- Testing
- intraosseus anesthesia, Conventional nerve block
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Healthy Volunteers
A Study to Assess Safety, Tolerability, and How Single and Multiple Injections or Infusions of ABBV-313 Affects the Body of Adult Participants
The objective of this study is to assess the safety, tolerability, pharmacokinetics, and immunogenicity of single and multiple doses of ABBV-313 in healthy adult participants.
- Trial name
- NCT07673120
- Testing
- ABBV-313
- Where
- 2 sites in United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- AbbVie
Diabetes Mellitus
Multiple Daily Injections and Continuous Glucose Monitoring in Diabetes
Evaluate if addition and use of real time continuous glucose monitoring (RT-CGM) improves glycemic outcome of patients using multiple daily injections (MDI) and self monitoring blood glucose (SMBG) testing, who are not at target…
- Trial name
- DIaMonD (NCT02282397)
- Testing
- Continuous Glucose Monitor
- Where
- 30 sites in United States, Canada
- Volunteers
- 316 people
- Sponsor
- DexCom, Inc.
SLE - Systemic Lupus Erythematosus, Systemic Sclerosis
CD19/BCMA-Targeted Universal CAR-T Cell Injection for the Treatment of Autoimmune Diseases
This is a single-arm, open-label, investigator-initiated trial (IIT) designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of RD06-05 in patients with autoantibody-mediated autoimmune…
- Conditions
- SLE - Systemic Lupus Erythematosus, Systemic Sclerosis, ANCA Associated Vasculitis, Idiopathic Inflammatory Myopathies
- Trial name
- NCT07596680
- Testing
- RD06-05 CAR-T Cell Injection
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nanjing Bioheng Biotech Co., Ltd.
Keratoconjunctivitis Due to Adenovirus, Viral Shedding
A Placebo Controlled Comparison of Topical Zirgan Versus Genteal Gel for the Treatment of Adenovirus Conjunctivitis
The investigators are conducting this study because the patient have an eye infection which is called adenoviral conjunctivitis, and is the most common cause of "pink eye". There is currently no treatment for this condition.
- Trial name
- NCT01533480
- Testing
- Zirgan, genteal gel
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Lifelong Vision Foundation
Sepsis-Induced Myocardial Dysfunction
Investigating the Clinical Benefits and Underlying Mechanisms of Danhong Injection in Modulating Mitochondrial Homeostasis Against Sepsis-Associated Myocardial Dysfunction
This study aims to evaluate the clinical efficacy of Danhong injection in patients with septic myocardial injury through a prospective randomized controlled trial.
- Trial name
- NCT07375862
- Testing
- Danhong injection, Saline
- Volunteers
- 140 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Healthy
A Study to Compare Two Formulations of LY3209590 in Healthy Participants
The main purpose of this study is to compare the two formulations of LY3209590 in healthy participants. Study participants will be administered each formulation at separate study visits.
- Trial name
- NCT05914688
- Testing
- LY3209590 (Formulation 1), LY3209590 (Formulation 2)
- Where
- Singapore
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Treatments of Striae Distensae
The Combination Therapy of Nanofat Grafting and PRP Compared With Microfat Grafting and PRP Synergy in Treating Striae Distensae
Striae distensae is caused by the fracture and damage of the elastic fibers and collagen fibers, which is still a difficulty to overcome.
- Trial name
- NCT03807986
- Testing
- Nanofat grafting, Microfat grafting, Platelet-rich plasma (PRP) Injection
- Where
- China
- Volunteers
- 12 people
- Sponsor
- First Affiliated Hospital of Jinan University
Age-Related Macular Degeneration
Study Of Combined VISUDYNE Therapy With Kenalog In CNV Secondary To Age-Related Macular Degeneration
To determine whether VISUDYNE therapy in combination with 4 mg intravitreal triamcinolone will reduce the average loss from baseline of best corrected visual acuity (BCVA) as compared with Visudyne therapy without intravitreal…
- Trial name
- NCT00140803
- Testing
- Visudyne, Kenalog
- Where
- 2 sites in United States, Canada
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
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