Clinical trials: Injections
Diabetic Macular Edema
Efficacy & Safety Trial of Intravitreal Injections Combined With PRP for CSME Secondary to Diabetes Mellitus (DAVE)
This study is a Phase I/II, multicenter, randomized, study of the efficacy and safety of ranibizumab injection monotherapy verses a duel therapy of 0.3mg ranibizumab combined with ultra wide, 200° field angiography guided pan…
- Trial name
- DAVE (NCT01552408)
- Testing
- 0.3 mg ranibizumab, Targeted Pan Retinal Photocoagulation
- Where
- 3 sites in United States
- Volunteers
- 29 people
- Sponsor
- David M. Brown, M.D.
Rabies
Effect of ERIG Injection on Day 7 After First Dose of Rabies Vaccination to Rabies Immune Response
No study was conducted to evaluate the rabies neutralizing antibody titers after RIG injection on day 7. The only study that has supported the delay of RIG administration was done in 1996 by our institute, of which RIG was given…
- Trial name
- NCT03524417
- Testing
- Equine rabies immunoglobulin injection on day 7
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Queen Saovabha Memorial Institute
Erosive Oral Lichen Planus
Efficacy of Intralesional Injection of Platelet Rich Plasma in the Treatment of Patients With Erosive Oral Lichen Planus
After signing the informed consent, the participant will be allocated to either intervention or control group, then each participant in the intervention group will receive intralesional injections of platelet rich plasma…
- Trial name
- NCT03293368
- Testing
- Platelet rich plasma, Triamcinolone Acetonide
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Female Infertility
Recombinant Follicle-stimulating Hormone in Treatment for Infertility
This is a randomized multi-centre, assessor-blind, parallel-group study to be conducted in 250 women in the age group of 20 to 39 years (both inclusive), who are indicated to undergo COS as part of assisted reproductive…
- Trial name
- REFRESH (NCT05266924)
- Testing
- Recombinant Human Follicle Stimulating Hormone 900 IU (66.0 μg) / 1.5mL Solution for Injection in Prefilled Pen
- Where
- India
- Volunteers
- 250 people
- Sponsor
- Bharat Serums and Vaccines Limited
Injection Site Infection, Substance Use Disorders
Integrated Care and Treatment for Severe Infectious Diseases and Substance Use Disorders Among Hospitalized Patients
The goal of this clinical trial is to test the effectiveness of an integrated infectious disease/substance use disorder (SUD) clinical team intervention approach in patients hospitalized with severe injection-related infections…
- Trial name
- CTN0121 (NCT05688423)
- Testing
- SIRI Team, Treatment as Usual
- Where
- 6 sites in United States
- Volunteers
- 480 people
- Sponsor
- Columbia University
Adhesive Capsulitis, Frozen Shoulder
ZILRETTA™ for Treatment of Idiopathic Adhesive Capsulitis
Adhesive capsulitis is a fairly common orthopedic condition that causes pain and loss of range of motion. There are a variety of ways to treat adhesive capsulitis, one of them being an intra-articular steroid injection.
- Conditions
- Adhesive Capsulitis, Frozen Shoulder, Adhesive Capsulitis of Shoulder
- Trial name
- NCT04831255
- Testing
- triamcinolone acetonide extended-release injectable suspension
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Virginia
Adrenal Suppression
Intra-articular Betamethasone and the Hypothalamic-pituitary-adrenal Axis
To evaluate the effect of intra-articular corticosteroid injection (IACI) of depot preparation of betamethasone on the hypothalamic-pituitary-adrenal (HPA) axis, in patients with osteoarthritis of the knee
- Trial name
- NCT01799408
- Volunteers
- 40 people
- Sponsor
- The Nazareth Hospital, Israel
Pain Management
Efficacy of Manual Pressure in Infants
Manual pressure is an effective, easy-to-apply, no preparation, and cost-effective method of reducing pain associated with the injection.
- Trial name
- NCT05143450
- Testing
- Manual Pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Biruni University
Healthy
A Research Study Looking at Similarity Between Tirzepatide Versions for Different Injection Devices
The main purpose of this study is to look at the amount of the study drug, tirzepatide, that gets into the blood stream and how long it takes the body to get rid of it when given using two different devices.
- Trial name
- NCT05810597
- Testing
- Tirzepatide, Single Dose Pen, Multi-use Prefilled Pen
- Where
- 3 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Multiple Sclerosis
Aerobic Exercise and Flu-like Symptoms Following Interferon Beta 1a Injections in Patients With Multiple Sclerosis?
The purpose of the present study is to test the hypothesis that aerobic training can reduce flu-like symptoms following interferon beta 1a injections in patients with Multiple Sclerosis.
- Trial name
- NCT02236624
- Testing
- Aerobic exercise
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Systemic Amyloidosis
124I-p5+14 Injection Safety in Subjects With Systemic Amyloidosis
This is a single-center, exploratory, Phase 1 Positron Emission Tomography/x-ray Computed Tomography (PET/CT) imaging study to detect amyloidosis that will enroll patients with a confirmed diagnosis of systemic amyloidosis.
- Trial name
- NCT03678259
- Testing
- 124I-p5+14 Injection
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of Tennessee Graduate School of Medicine
Satisfaction, Self-regulation, Injection Skills
Evaluation of the Effectiveness of Two Different Teaching Methods in Nursing Students
Aim: The aim of this study is to evaluate the effects of computer-assisted games and high-fidelity simulation methods in developing intramuscular (IM) injection application skills among nursing students.
- Trial name
- NCT07584980
- Testing
- SİMÜLATİON, COMPUTER GAMES
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kocaeli Sağlık ve Teknoloji Üniversitesi
Tennis Elbow, Musculoskeletal Diseases
Trial of Physiotherapy and Corticosteroid Injections in Lateral Epicondylalgia
This randomised controlled trial will evaluate the role of manual therapy and therapeutic exercise and corticosteroid injections in the treatment of lateral epicondylalgia (tennis elbow).
- Trial name
- NCT00110318
- Testing
- Manual therapy and therapeutic exercise, Corticosteroid injections
- Where
- Australia
- Volunteers
- 198 people
- Sponsor
- The University of Queensland
Breast Cancer, Sentinel Lymph Node
Pain Control for Breast Cancer Patients Receiving Injection of Radioactive Tracer
The purpose of this study is to compare the effectiveness four different pain treatments for the injection of radioactive tracer that women with breast cancer receive for sentinel lymph node biopsies.
- Conditions
- Breast Cancer, Sentinel Lymph Node, Breast Neoplasms, Breast Cancer Female
- Trial name
- NCT04822597
- Testing
- Lidocaine patch, Buzzy(R), Ice pack
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- University of Wisconsin, Madison
Frozen Shoulder, Chronic Pain
Comparison of Transcatheter Arterial Microembolization and Corticosteroid Injection and for Treatment of Frozen Shoulder
Objectives： This study aims to compare the efficacy of transcatheter arterial microembolization (TAME) and corticosteroid injection for treatment of frozen shoulder.
- Conditions
- Frozen Shoulder, Chronic Pain, Adhesive Capsulitis, Transcatheter Arterial Microembolization
- Trial name
- NCT07696923
- Testing
- TAME group, CS injection group
- Where
- Taiwan
- Volunteers
- 94 people
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Advanced Solid Cancer
A Study of MHB046C Injection in Patients With Advanced Solid Tumors
This is a first-in-human, open-label, multicenter Phase I/II study of MHB046C in patients with advanced solid tumors. The study was designed to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of…
- Trial name
- NCT06985355
- Testing
- MHB046C
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Minghui Pharmaceutical (Hangzhou) Ltd
Non-small Cell Lung Cancer
Study to Evaluate the Bioavailability of Tislelizumab Via Subcutaneous Injection in First-Line Treatment of Participants With Advanced or Metastatic Non-Small Cell Lung Cancer
This is an open-label, multicenter, Phase 1 clinical study to evaluate the bioavailability of tislelizumab subcutaneous (SC) injection in the first-line treatment of participants with advanced or metastatic non-small cell lung…
- Trial name
- NCT06091943
- Testing
- Tislelizumab IV, Tislelizumab SC, Histology-Based Chemotherapy Doublet
- Where
- 15 sites in China, Georgia and 1 more
- Volunteers
- 62 people
- Sponsor
- BeiGene
Healthy
Study of LY3074828 in Healthy Participants
The purpose of this study is to evaluate different concentrations and formulations of LY3074828 compared to placebo ("dummy drug"). The study will consist of 2 parts: Part A and Part B.
- Trial name
- NCT03748940
- Testing
- LY3074828, LY900021
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Chemotherapy-induced Neutropenia
Recombinant Human Serum Albumin/Granulocyte Colony Stimulating Factor Fusion Protein for Breast Cancer Patients
Evaluation of the efficacy and safety of recombinant human serum albumin / granulocyte-stimulating factor fusion protein for injection to prevent chemotherapy-induced neutropenia
- Trial name
- NCT03251768
- Testing
- rHSA-GCSF 2.4mg, GCSF
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Tianjin SinoBiotech Ltd.
Macular Edema, Retinal Vein Occlusion
Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO
This is a Phase 3, multicenter, randomized, masked, controlled, parallel group study of 12 months duration in treatment naïve subjects with RVO.
- Trial name
- SAPPHIRE (NCT02980874)
- Testing
- suprachoroidal CLS-TA, IVT aflibercept
- Where
- 110 sites in United States, Australia and 14 more
- Volunteers
- 460 people
- Sponsor
- Clearside Biomedical, Inc.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.