Clinical trials: Injections
Hepatocellular Carcinoma, Immunotherapy
A Single-Arm, Multicenter, Exploratory Clinical Study of TACE Combined With Iparomlimab and Tuvonralimab Injection (QL1706) and Lenvatinib for Perioperative Treatment of Resectable Hepatocellular Carcinoma
This is a single-arm, multicenter, exploratory clinical study evaluating the efficacy and safety of TACE combined with Iparomlimab and Tuvonralimab Injection (QL1706) and lenvatinib for perioperative treatment of resectable HCC…
- Conditions
- Hepatocellular Carcinoma, Immunotherapy, Preoperative, PD-1
- Trial name
- NCT07131501
- Testing
- Radical surgery, TACE treatment, Iparomlimab and Tuvonralimab Injection (QL1706)
- Where
- China
- Volunteers
- 48 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Diabetes Mellitus Type 2
The Necessity of an Injection-Meal-Interval in Patients With Type 2 Diabetes Mellitus and Therapy With Human Insulin
The purpose of the study is to demonstrate, that there is no difference in metabolic control in patients with type 2 diabetes mellitus and therapy with human insulin with or without injection-meal-interval.
- Trial name
- NCT00529165
- Testing
- injection-meal-interval
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Jena
Osteoarthritis,Knee
The Comparative Efficacy of Peri-articular and Intraarticular Tranexamic Acid in Total Knee Arthroplasty
Post-operative bleeding in total knee arthroplasty (TKA) can result in hypovolemic shock and unnecessity for allogenic blood transfusions.
- Trial name
- NCT03074994
- Testing
- Peri-articular TXA (15 mg/kg), Intraarticular TXA 2 g (40 mL), TXA combined with multimodal local anesthetic infiltration inject into peri-articular area
- Where
- Thailand
- Volunteers
- 108 people
- Sponsor
- Thammasat University
Multiple Sclerosis (MS)
A Clinical Study to Evaluate the Safety and Efficacy of GT802 Injection in the Treatment of Relapsing/Refractory Multiple Sclerosis
This is a single-arm, open-label, dose-escalation clinical trial intended to evaluate the safety, efficacy and cellular pharmacokinetics of GT802 for the treatment of relapsing/refractory multiple sclerosis.
- Trial name
- NCT07748637
- Testing
- GT802 Injection
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Daishi Tian
Prenatal Diagnosis
Sufentanil Pharmacokinetics After Intra Amniotic Injection
The fetus may be exposed during pregnancy to nociceptive stimuli because of fetal pathology (e.g., malformation) or a diagnostic or therapeutic procedure. To date, there is very little data and no consensus on fetal analgesia.
- Trial name
- 2IAS (NCT02962830)
- Testing
- Sufentanil
- Where
- France
- Volunteers
- 8 people
- Sponsor
- University Hospital, Lille
Thrombocytopenia, Hematologic Malignacies
Efficacy and Safety of MegaLT Injection for Platelet Recovery After Umbilical Cord Blood Transplantation
This is a single-arm, early safety and feasibility exploratory study to evaluate the efficacy and safety of MegaLT Injection in promoting platelet recovery after umbilical cord blood transplantation.
- Conditions
- Thrombocytopenia, Hematologic Malignacies, Platelet Recovery After Umbilical Cord Blood Transplantation
- Trial name
- NCT07696767
- Testing
- MegaLT Injection
- Volunteers
- 7 people
- Sponsor
- Anhui Provincial Hospital
Intracytoplasmic Sperm Injection, GnRH Agonist
Effect of GnRH Agonist Treatment Protocols on Ovarian Reserve
This study aimed to compare the gonadotropin-releasing hormone agonist (ultra-short) protocol versus (short and long) protocols on ovarian reserve in women undergoing intracytoplasmic sperm injection
- Conditions
- Intracytoplasmic Sperm Injection, GnRH Agonist, Infertility, Ovarian Reserve
- Trial name
- NCT05567731
- Testing
- ultrashort GnRHa, short GnRHa, long GnRHa
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Platelet Rich Plasma Injection, Ultrasonography
The Effects of Intra-articular and Peri-articular Platelet-rich Plasma (PRP) Injections ın Chronic Knee Osteoarthritis
The primary objective of this study is to evaluate and compare the effectiveness of ultrasound-guided combined intra-articular and peri-articular platelet-rich plasma (PRP) injections with intra-articular PRP injections alone in…
- Conditions
- Platelet Rich Plasma Injection, Ultrasonography, Gonarthrosis
- Trial name
- NCT07339137
- Testing
- Conservative Therapy, Intra-Articular PRP, Peri-Articular PRP
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara City Hospital Bilkent
Safety and Effectiveness Between Intravesical Platelet-rich Plasma Injection in Patients With Interstitial Cystitis/Bladder
Intravesical Platelet-rich Plasma Injection in Patients With Interstitial Cystitis/Bladder-A Retrospective Study
The correlation of safety and effectiveness between intravesical platelet-rich plasma injection in patients with interstitial cystitis/bladder-A retrospective study to evaluate the correlation of safety and effectiveness between…
- Trial name
- NCT06339645
- Testing
- PRP
- Where
- Taiwan
- Volunteers
- 658 people
- Sponsor
- Hualien Tzu Chi General Hospital
Melanoma, Urological Cancer
Safety and Tolerability of Recombinant Humanized Anti-PD-1 Monoclonal Antibody Toripalimab for Patients With Advanced Solid Tumors
This is a mono-center, open-label, phase 1 study evaluating the humanized anti-PD-1 antibody JS001, as a monotherapy in patients with advanced melanoma or urological cancers who have failed in routine systemic treatment.
- Trial name
- NCT02836795
- Testing
- humanized anti-PD-1 monoclonal antibody Toripalimab (JS001)
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Shanghai Junshi Bioscience Co., Ltd.
Carcinoma, Hepatocellular
Comparison Between Radiofrequency Versus Ethanol Injection for the Treatment of Hepatocellular Carcinoma
Ethanol injection has been for many years the standard approach as percutaneous treatment of non-surgical early hepatocellular carcinoma in cirrhotic patients.
- Trial name
- NCT00355212
- Testing
- percutaneous ablation of hepatocellular carcinoma
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Azienda Ospedaliera San Giovanni Battista
Ankle Osteoarthritis
A Single Intraarticular Injection of Platelet-Rich Plasma on Pain and Physical Function in Patients With Ankle OA
Platelet-rich plasma (PRP) has been reported to be an effective treatment for knee osteoarthritis (OA). The application in ankle OA has rarely been investigated.
- Trial name
- NCT04022928
- Testing
- PRP
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Human Papilloma Virus, Infections
Impact Of Intralesional Tuberculin Ppd Injection On Anogenital
This clinical study investigates the immunological effects of tuberculin purified protein derivative (TPPD) therapy in patients with anogenital warts (AGW) caused by human papillomavirus (HPV).
- Trial name
- NCT07072065
- Testing
- protein purified derivative
- Where
- Indonesia
- Volunteers
- 24 people
- Sponsor
- Universitas Padjadjaran
Breast Cancer
A Study for the Adjuvant Treatment of Breast Cancer
Studies on postoperative adjuvant albumin paclitaxel in domestic breast cancer patients are less reported, especially in large samples, and more studies focus more on the safety and tolerability of albumin paclitaxel use.
- Trial name
- NCT05420467
- Testing
- Docetaxel, Carboplatin, Trastuzumab
- Where
- China
- Volunteers
- 2,413 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Chronic Shoulder Pain
Effects of Ultrasound-guide Hypertonic Dextrose Injection for Chronic Subacromial Bursitis
The aim of this study is to investigate the echoguide hypertonic injection and compared steroid injection in subacromial bursitis patients about clinical and ultrasound image presentation.
- Trial name
- NCT04916353
- Testing
- hypertonic dextrose water, Triamcinolone Acetonide.
- Where
- 2 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Intracerebral Hemorrhage
Deproteinised Calf Blood Serum Injection for the Treatment of Acute Intracerebral Hemorrhage
The purpose of this study is to investigate the efficacy and safety of Deproteinised Calf Blood Serum Injection in alleviating perihematomal edema (PHE) and secondary brain injury, as well as neurologic deficits in patients with…
- Trial name
- NCT03260153
- Testing
- Deproteinised Calf Blood Serum Injection
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Beijing Tiantan Hospital
Snoring, Apnea
Injection Snoreplasty: Comparison Between Ethanol and Ethanolamine Oleate
SUMMARY INTRODUCTION: among various treatments for patients with primary snoring, upper airway resistance syndrome (UARS) and obstructive sleep apnea syndrome (OSAS), the injection snoreplasty arose as a promising alternative in…
- Trial name
- NCT00804037
- Testing
- Injection Snoreplasty
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Femoroacetabular Impingement
Platelet-rich Plasma Versus Corticosteroid Injection for the Treatment of Femoroacetabular Impingement
The purpose of this study is to compare the clinical response of intra-articular platelet rich plasma (PRP) versus corticosteroid injection in patients affected by femoroacetabular impingement (FAI).
- Trial name
- NCT02920177
- Testing
- platelet-rich plasma injection, Kenalog 10 MG/ML Injectable Suspension
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Michigan
Neck Muscle Issue
BoTox Into the Sternocleidomastoid Muscles (SCM)
Botulinum toxin injections have been used both in the face and neck for many years. However, injection into the sternocleidomastoid muscle (SCM) has only been done to treat neck spasms.
- Trial name
- NCT06903975
- Testing
- prabotulinumtoxinA-xvfs
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Epicondylitis
Platelet Rich Plasma (PRP) in Chronic Epicondylitis
Background Tendinopathy is a difficult problem to manage and can result in significant patient morbidity. Currently, the clinical use of PRP in painful tendons is widespread but its efficacy remains controversial.
- Trial name
- B-PRPtendon (NCT01945528)
- Testing
- US-guided tenotomy with PRP, US-guided tenotomy with lidocaine
- Where
- 2 sites in Spain
- Volunteers
- 86 people
- Sponsor
- Jose Ignacio Martin
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