Clinical trials: Injuries, Knee
Sports Injury
Clinical Study of Platelet-rich Plasma Promoting Tendon-bone Healing in Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) injury is a common knee injury, which seriously affects the living ability and sport level of the injured. ACL reconstruction is the main method to treat ACL injury.
- Trial name
- NCT04659447
- Testing
- Platelet-Rich Plasma
- Volunteers
- 60 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Knee Osteoarthritis
Intrawound Administration of Vancomycin in TKA
The purpose of this study is to determine the intra-articular and serum levels of vancomycin over the first 24 hours postoperatively after intra-articular administration of a standard dose of vancomycin in primary total knee…
- Trial name
- NCT05338021
- Testing
- Intrawound administration of vancomycin after closure of the arthrotomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Knee Osteoarthritis, Hip Osteoarthritis
Comparison of Knotless Barbed Suture and Standard Suture in Knee Replacement Patients
Barbed suture use has been gaining increased acceptance and has been reported to offer potential advantages in wound closure of hip and knee replacement surgeries.
- Trial name
- NCT03031314
- Testing
- barbed suture, standard suture
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Washington Hospital Healthcare System
Meniscus Lesion, Knee Injuries
"Intra-articular Hyaluronic Acid Injection for Accelerating Functional Recovery After Knee Arthroscopy"
This study evaluates the effectiveness of intra-articular hyaluronic acid (HA) viscosupplementation and oral chondroitin sulfate (CS) supplementation, in combination with standard postoperative rehabilitation, on functional…
- Conditions
- Meniscus Lesion, Knee Injuries, Medial Meniscus Tear
- Trial name
- NCT07476508
- Testing
- Standard Postoperative Rehabilitation Protocol, Oral Chondroitin Sulfate (Flextrum), ntra-articular Hyaluronic Acid Injection (Biolevox)
- Where
- 2 sites in Poland
- Volunteers
- 290 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Osteoarthritis, Knee, Knee Injuries
Impact of Mulligan Squeeze Technique on Meniscal Derangement in Knee Osteoarthritis Patients
The objective of this study is to find out the effects of Mulligan's Squeeze technique added as a complementary treatment to the conventional physiotherapy for the management of meniscal derangement in knee osteoarthritis…
- Conditions
- Osteoarthritis, Knee, Knee Injuries, Meniscus; Derangement, Meniscus Tear
- Trial name
- NCT06391047
- Testing
- Mulligan's Squeeze Technique - manual therapy, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Faisalabad
Knee Injury
Evaluation of the CR Plug (Allograft) for the Treatment of a Cartilage Injury in the Knee.
Determine the ability of the allograft plug for the treatment of a cartilage injury in the knee
- Trial name
- NCT00793104
- Testing
- Placement of allograft CR Plug in primary injury site
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- RTI Surgical
Anterior Cruciate Ligament Tear, Osteoarthritis, Knee
Long Term Clinical and Radiographical Outcomes of Different Anterior Cruciate Ligament Reconstruction Techniques
The purpose of this study is to evaluate the long-term results of various anterior cruciate ligament reconstruction techniques. This assessment is necessary for the current context of anterior cruciate ligament research as…
- Trial name
- NCT05088278
- Testing
- Anatomical single bundle ACL reconstruction with hamstrings, Anatomical single bundle ACL reconstruction with patellar tendon, ACL reconstruction with over the top plus lateral plasty technique
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- Istituto Ortopedico Rizzoli
Arthritis Knee
Preoperative Radiographic Evaluation of Medial Tibiofemoral Knee Osteoarthritis
Observational study.
- Trial name
- RX-FTI (NCT03704558)
- Sponsor
- Rennes University Hospital
Healthy
Biomechanics Responses to Power and Strength Combined Training
Anterior cruciate ligament (ACL) is the most frequently injured knee ligament during performance of recreational activities and sports.
- Trial name
- NCT04139187
- Testing
- Combined training with power and strength exercises
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Maria
Anterior Cruciate Ligament (ACL) Tear
Augmented Reality in Surgery
The goal of this observational study is to learn whether an artificial-intelligence software can reliably recognise the anatomical landmarks used to guide femoral bone tunnel placement on the arthroscopic monitor image during…
- Trial name
- ARS (NCT07636278)
- Testing
- Primary arthroscopic anterior cruciate ligament reconstruction
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Anterior Cruciate Ligament Injuries
Perturbation Training vs Functional Activities on Pain, ROM, Balance, and Function Post-ACL
Anterior cruciate ligament (ACL) injuries are among the most common and functionally disabling knee injuries, particularly in physically active individuals.
- Trial name
- NCT07642752
- Testing
- Perturbation Training Group, Task-Oriented Functional Activities Group, Control Group (Standard Rehabilitation Protocol)
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Injury, Knee
Descriptive Study of Multiligamentary Reconstruction of the Knee
Evaluation of clinical results and postoperative laxity after single-stage reconstruction of multiligamentous lesions of the knee. Comparison of two types of transplant: allograft versus autograft.
- Trial name
- NCT03932838
- Testing
- Clinical and radiologic evaluation
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Versailles Hospital
Meniscus Injury
Clinical Application Research of Combined Therapy in ERAS for Accelerated Orthopedic Rehabilitation
The double-blind method is adopted.Case selection Patients who underwent meniscus repair surgery under knee arthroscopy at Li Huili Hospital Affiliated to Ningbo University, the 906th Hospital of the People's Liberation Army…
- Trial name
- NCT07273032
- Testing
- Blank control group, Henggu Bone Injury Healing Agent Intervention Group, Lower limb rehabilitation training system intervention group
- Volunteers
- 120 people
- Sponsor
- Ningbo Medical Center Lihuili Hospital
Articular Cartilage Disorder of Knee, Osteoarthritis, Knee
Mesenchymal Stem Cells in Knee Cartilage Injuries
Induction of autologous repair chondrogenesis to regenerate injured articular cartilage using bone marrow mesenchymal stem cells (MSCs) after in vitro expansion under restricted culturing conditions.
- Trial name
- NCT02118519
- Testing
- Autologous Mesenchymal Stem Cells
- Where
- Jordan
- Volunteers
- 13 people
- Sponsor
- University of Jordan
Total Knee Arthroplasty, Total Hip Arthroplasty (THA)
AI-based Rehabilitation for Hip and Knee Surgery Patients
This study aims to evaluate the efficacy and safety of an AI-based home rehabilitation application ("Exersite Rehab") for patients who have undergone hip or knee arthroplasty(Total Knee Arthroplasty (TKA), Total Hip Arthroplasty…
- Conditions
- Total Knee Arthroplasty, Total Hip Arthroplasty (THA), Hip Fracture Surgery
- Trial name
- NCT07505628
- Testing
- Exersite Rehab (AI-based Mobile Application), Printed Educational Brochure (Traditional Rehabilitation)
- Where
- 2 sites in South Korea
- Volunteers
- 106 people
- Sponsor
- Gangnam Severance Hospital
Patella Fracture
Comparison of Patella Plating Versus Tension Band Wiring for the Treatment of Unstable Patellar Fractures
This study aims to compare the efficacy and safety of patella anatomical locking plate fixation versus tension band wiring in the treatment of patellar fractures.
- Trial name
- WASP (NCT06981039)
- Testing
- Patella Anatomical Locking Plate, Tension Band Wiring
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Patella Dislocation Recurrent, Patellar Dislocation
Clinical Outcomes Following Patellar Dislocation in Young Athletes
The purpose of this study is to identify predictors of future injury and disability following LPD. The investigators' long term goal is to improve longitudinal outcomes of athletes with LPD following surgical and non-surgical…
- Trial name
- NCT03040232
- Testing
- biomechanical assessment
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Recurrent Patellar Dislocation, Osteotomy
The Clinical Results of Derotational Osteotomy Based on 3D Osteotomy Template for Treatment of Recurrent Patellar Dislocation Combined With Patellofemoral Maltracking
For severe recurrent patellar dislocation with poor patellar maltracking, derotation osteotomy is an effective clinical treatment. However, derotation osteotomy requires very high requirements for the surgeon.
- Conditions
- Recurrent Patellar Dislocation, Osteotomy, Patellar Maltracking
- Trial name
- NCT04556799
- Testing
- computer-assisted surgery, traditional osteotomy
- Volunteers
- 50 people
- Sponsor
- Beijing Jishuitan Hospital
Knee Injuries, Knee Injuries and Disorders
Opioid Reduction Program for Total Knee Replacement Patients
In the context of prescribed opioids, research suggests that increased exposure is associated with long-term opioid use. Orthopedic surgeries are associated with the prescribing of more opioid narcotics than any other surgical…
- Conditions
- Knee Injuries, Knee Injuries and Disorders, Opioid Use
- Trial name
- TKR ORP (NCT05414942)
- Testing
- Opioid Reduction Program
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Tennessee
Anterior Cruciate Ligament Injury
Light Load Blood Flow Restriction Training in Anterior Cruciate Ligament Reconstruction Patient Rehabilitation
This study is examining the post-operative rehabilitation of anterior cruciate ligament (ACL) reconstruction patients within the National Health Service (NHS).
- Trial name
- NCT03419169
- Testing
- Light load BFR resistance training, Heavy load resistance training
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
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