Clinical trials: Injuries, Knee
Knee Injury
Electromyostimulation and Strength Walking for Knee Injuries
The purpose of this project is to compare three treatment regimens for knee injury to the standard rehabilitation protocol: 1) NMES, 2) graduated strength walking (via a weighted vest), and 3) NMES combined with graduated…
- Trial name
- KI (NCT02065518)
- Testing
- NMES, Strength Walking, Standard Rehabilitation Protocol
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- University of Tennessee
Anterior Cruciate Ligament Rupture
Efficacy of Preoperative Re-education on Patients With an Anterior Cruciate Ligament Rupture
Anterior cruciate ligament (ACR) rupture is a common lesion of sportsmen that leads to functional deficits which are difficult to overcome.
- Trial name
- PRELIG (NCT02505659)
- Testing
- Preoperative re-education
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Patella Fracture
Effects Of Intra-Operative Intra-Articular Cocktail Injection In Patella Open Reduction And Internal Fixation
The objective of this study is to demonstrate the safety and efficacy of an intra-articular analgesics cocktail injection for post-operative patella fracture fixation patients, by comparing post-operative pain relief and…
- Trial name
- NCT07006168
- Testing
- Ketorolac 15mg, Triamcinolone Acetonide 40mg, Ropivacaine HCL 1% 15ml
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- The University of Hong Kong
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease
Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term)…
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Trial name
- PATHFINDER (NCT04229563)
- Testing
- AURYON Atherectomy System
- Where
- 10 sites in United States
- Volunteers
- 102 people
- Sponsor
- Angiodynamics, Inc.
Femur Fracture
Vastus Intermedius Dry Needling for Knee Stiffness Resulted From Surgically Managed Femoral Fractures With Open Reduction & Internal Fixation.
Orthopedic traumatic injuries are considered a major health epidemic, challenged by high morbidity, mortality, and socioeconomic burden.
- Trial name
- NCT06307587
- Testing
- dry needling
- Volunteers
- 44 people
- Sponsor
- Al-Razi Hospital
Anterior Cruciate Ligament Rupture
"Online Surveys" in Perioperative Knee Anterior Cruciate Ligament (ACL) Reconstruction
To monitor the quality of health care systems, patient-reported outcome measures (PROMs) should be collected and analyzed before and after medical interventions.
- Trial name
- ORTHENSE (NCT05423314)
- Testing
- knee brace cold therapy
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Toulouse
Rupture of Posterior Cruciate Ligament, Rupture of Anterior Cruciate Ligament
Simultaneous Multiple Cruciate Ligament Reconstructions Using a Single Achilles Allograft
This study introduce cases of simultaneous multiple cruciate ligament reconstructions with a single free tendon Achilles allograft using new technique.
- Trial name
- NCT01440348
- Testing
- cruciate ligament reconstruction
- Where
- South Korea
- Volunteers
- 51 people
- Sponsor
- National Police Hospital
Foreign-Body Reaction, Inflammation
IMPACT: Safety and Feasibility of a Single-stage Procedure for Focal Cartilage Lesions of the Knee.
Articular cartilage defects in the knee have a poor intrinsic healing capacity and may lead to functional disability and osteoarthritis.
- Conditions
- Foreign-Body Reaction, Inflammation, Effusion (L) Knee, Knee Pain Swelling
- Trial name
- IMPACT (NCT02037204)
- Testing
- Cartilage repair surgery
- Where
- Netherlands
- Volunteers
- 35 people
- Sponsor
- UMC Utrecht
Periprosthetic Fracture Around Prosthetic Joint Implant
Investigating Periprosthetic Fracture Cultures in Arthroplasty
This study aims to improve how doctors diagnose infections in patients with broken bones around joint replacements. Currently, there are no clear guidelines to help determine when an infection is present, making treatment…
- Trial name
- NCT06952738
- Testing
- Not applicable- observational study
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Chicago
Tibial Plateau Fracture
Personalized Weight-Bearing With Smart Crutch Tips After Surgery for Tibial Plateau Fractures
This study will compare two approaches to rehabilitation after surgery for a fracture of the upper part of the shinbone that involves the knee joint (tibial plateau fracture).
- Trial name
- NCT07897149
- Testing
- Crutch Tip Biofeedback System, Individualized FEA-Guided Postoperative Weight-Bearing, Usual-Care Postoperative Weight-Bearing
- Volunteers
- 86 people
- Sponsor
- Comeback Mobility Inc
Degenerative Lesion of Articular Cartilage of Knee
Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects
The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the…
- Trial name
- NCT02090140
- Testing
- ADSC Application, Microfracture
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- University of Colorado, Denver
Tibial Plateau Fracture
Efficacy of the Use of 3D Printing Models in the Treatment of Tibial Plateau Fractures: a Randomized Clinical Trial
TIBIA3D is a randomized, open and prospective clinical trail that evaluates the use of preoperative 3D printing in the surgical treatment of patients with tibial plateau fractures
- Trial name
- NCT05571449
- Testing
- Open reduction and internal fixation, Standard osteosynthesis planning, 3-D model osteosynthesis planning
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Pedro-José Torrijos-Garrido
Knee Injuries
Establishing the Clinical Significance Values of the Lysholm Knee Score
The goal of this observational study is to learn about patients who will undergo anterior cruciate ligament reconstruction. The main questions it aims to answer are: What is the minimal clinically important difference value of…
- Trial name
- NCT06571227
- Testing
- Anterior cruciate ligament reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Kırklareli University
Lower Limb Amputation Below Knee (Injury)
Descriptive Study of Receptive Fields in Lower Limb Amputees
It has been observed that patients subjected to amputations develop so called receptive fields, which time of occurrence and localization over time are yet not examined systematically.
- Trial name
- NCT03348605
- Testing
- Phantom Stimulator, Cort X Sensorics, Spaichingen, Germany
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- Rehaklinik Bellikon
Anterior Cruciate Ligament Rupture
Anatomic and Biomechanical Investigation on ACL: A Cadaveric Study
The present study was aimed to investigate the kinematics differences between round-tunnel (ROT) and flat-tunnel (FLT) techniques and compare the influence to the anterior root of lateral meniscus (ARLM ) in anterior cruciate…
- Trial name
- NCT04957797
- Testing
- round tunnel, flat tunnel
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Peking University Third Hospital
Hallux Valgus
The Effect of Hallux Valgus Angle on Dynamic Knee Movement Pattern
Abstract Background/aim: Little is known about the relationship between hallux valgus and the alignment of proximal joints. Dynamic knee valgus is a movement pattern characterized by excessive knee abduction along with femoral…
- Trial name
- NCT06563037
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Proximal Tibia Fracture
The Efficacy and Cost Effectiveness of Preoperative and Postoperative Cryotherapy in Proximal Tibia Fractures
Consenting patients with proximal tibia fractures will be randomized to 10 degree or 21 degree cryotherapy sleeves. Time to discharge and complications will be monitored.
- Trial name
- ARCTIC CAT (NCT01104831)
- Testing
- Cryotherapy, Room temperature cuff
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Osteochondritis Dissecans, Osteoarthritis
ACI-C Versus AMIC. A Randomized Trial Comparing Two Methods for Repair of Cartilage Defects in the Knee
ACI-C versus AMIC: A controlled randomized trial comparing Autologous Chondrocyte Implantation ( ACI) and Autologous Matrix Induced Chondrogenesis (AMIC) for repair of cartilage defects in the knee.
- Conditions
- Osteochondritis Dissecans, Osteoarthritis, Cartilage Injury, Osteonecrosis
- Trial name
- NCT01458782
- Testing
- Treatment of cartilage defects in the knee
- Where
- Norway
- Volunteers
- 41 people
- Sponsor
- University Hospital of North Norway
Knee Injuries
Virtual Reality Rehabilitation for Patients With Anterior Cruciate Ligament Reconstruction
The purpose of this study is to ascertain whether 4 weeks of daily virtual-reality-based rehabilitation at home improves disability in the early stages of recovery from anterior cruciate ligament reconstruction surgery compared…
- Trial name
- NCT05080894
- Testing
- Virtual reality
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Institut d'Investigacions Biomèdiques August Pi i Sunyer
Knee Osteoarthritis, Knee Injuries
The Relationship Between Disease Severity and Various Lower Extremity Parameters in Individuals With Knee Osteoarthritis
This study perform to investigate the relationship between quadriceps femoris (QF) strength, QF thickness, femoral cartilage thickness, knee function, balance, kinesiophobia and gait of the patients with knee osteoarthritis.
- Trial name
- NCT05294224
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Dilara Özen Oruk
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