Clinical trials: Injuries
Spinal Cord Injuries, Muscle Spasticity
Cyproheptadine and Chlorpromazine Effects on Spasticity
The main goal of this research is to understand the neuronal mechanisms that mediate the development of spasticity and motor dysfunction after spinal cord injury.
- Trial name
- NCT01509885
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Anxiety, Pain
Text Message Study
The objectives of this double-blind, randomized, controlled study are to evaluate the efficacy of maintaining contact with low-back pain patients through text messaging and emailing, to decrease anxiety levels, pain, number of…
- Conditions
- Anxiety, Pain, Surgical Site Infection
- Trial name
- NCT01789697
- Testing
- cellular device/computers
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Duke University
Lower Limb Ligament Injury
Relationship Between Proprioceptive Flexibility and the Occurrence of Lower Limb Ligament Injury in Pivot-contact Sports
Among young athletes involved in pivot and pivot-contact sports (soccer, handball, rugby, etc.), lateral ankle sprains and lesions of the anterior cruciate ligament (ACL) are the most frequent ligament injuries.
- Trial name
- FlexiPro (NCT07028723)
- Testing
- proprioceptive profile measurement
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Sport Injury
Epidemiology of Injuries During Crossfit Practice
This study aims to precisely describe epidemiology of injuries than occur during practice of crossfit. Each participant will complete questionnaires in order to identify injuries.
- Trial name
- EPITRAUMA-CF (NCT05199220)
- Testing
- Questionnaire
- Where
- Reunion
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Stroke, Traumatic Brain Injury
Validation of an Obstacle Course Used in Patients With Muscle Tightness
This study is being conducted to compare healthy patients versus patients with muscle tightness in their leg(s) after an acquired brain injury using walking trials time, a balance test, and foot pressure data.
- Conditions
- Stroke, Traumatic Brain Injury, Multiple Sclerosis, Spasticity
- Trial name
- NCT00776048
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Intervention, Injury Prevention
Resistance Band Training Versus Nordic Hamstring Exercise on Hamstring Strength Among Football Players
The major aim of this project to compare the effects of Resistance band training and Nordic hamstring exercise on hamstring strength among football players.
- Trial name
- NCT05220215
- Testing
- Nordic Hamstring Exercise, Hamstring Curl with Resistance band
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Aging, Heat Stress
Physiological Responses in Young and Older Adults During a Prolonged Simulated Heatwave
Climate change not only affects the planet's natural resources, but also severely impacts human health. An individual's ability to adequately cope with short- or long-term increases in ambient temperature is critical for…
- Conditions
- Aging, Heat Stress, Physiological Stress
- Trial name
- HW1 (NCT04353076)
- Testing
- Simulated heatwave exposure, Simulated heatwave exposure with mid-day cooling
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Sexual Violence
Developing and Testing a Trauma-Informed Exercise Intervention for Women Veterans With Histories of Sexual Violence
Exposure to sexual violence disproportionally impacts women Veterans and can have profound negative impacts on daily functioning.
- Trial name
- NCT06746740
- Testing
- Exercise
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Skull Base Neoplasms, Cerebrospinal Fluid Leakage
Role of Novel RADA16 Hydrogel in Endoscopic Skull Base Surgery
The purpose of this study is to specifically evaluate the effectiveness of PuraGel, a RADA16 polypeptide hydrogel, in expediting post-operative healing and re-mucosalization of the nasoseptal flap harvest site during endoscopic…
- Conditions
- Skull Base Neoplasms, Cerebrospinal Fluid Leakage, Nasal; Hypertrophy, Mucous Membrane (Septum)
- Trial name
- NCT05898074
- Testing
- Non-Absorbable Packing (Silastic Splint), PuraGel (RADA16) Hydrogel
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Surgical Site Infection, Microbial Colonization
P.Acnes Colony Count Following Subdermal Cefazolin
The specific outcome is to determine whether the colony count of Propionibacterium acnes, one of the commonest causes of shoulder infection and not eradicated by conventional forms of surgical preparatory solutions and…
- Trial name
- NCT03853096
- Testing
- Cefazolin
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Physical Therapy Techniques
Heat Transfer by Three Types of Packs and Its Implication on the Flexibility of the Lower Back
The purpose of this study is to compare the effects generated by the application of three different packs on the flexibility of the lower back of sedentary students.
- Trial name
- NCT02391376
- Testing
- moist heat pack; ;, seed pack, gel pack
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universidad Católica del Maule
Intergenerational Trauma
Child Cognitive-Affective Resilience Following 13-11 Event : A Pluridisciplinary Study of Intergenerational Transmission of a Traumatic Event
CARE 13-11 study explores the transmission of trauma within families. Exposure to a traumatic event can have an impact on those directly exposed, but also on their family.
- Trial name
- CARE 13-11 (NCT07203443)
- Testing
- MRI, Psychological assessment, Cognitive assessment
- Where
- France
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Alcohol Use, Underage, Alcohol Problem Drinking
Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change
This study will be the first to explore mindfulness as a prevention intervention among transition age youth and those with previous involvement in the juvenile or criminal justice system with substance use problems and history of…
- Conditions
- Alcohol Use, Underage, Alcohol Problem Drinking, Substance Use
- Trial name
- NCT04160754
- Testing
- Mindfulness Based Relapse Prevention, Control (CTL)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Keratoconus, Ocular Surface Disease
Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE Fitting
EYEdeal Scanning Technology enables rapid measurement of corneal and scleral topography. By accurately measuring the ocular surface with this imaging technology, the current iterative fitting method required to fit PROSE…
- Conditions
- Keratoconus, Ocular Surface Disease, Pellucid Marginal Corneal Degeneration, Ectasia
- Trial name
- NCT04649177
- Testing
- Ocular surface optical coherence tomography
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Boston Sight
Sports Medicine Injuries
Effect of STRAIN COUNTER-STRAIN ON PATIENTS WITH ANKLE SPRAINS
patients (male and female) will be participate at the study complain of acute to subacute ankle sprain. Orthopedic surgeons who will be responsible for the diagnosis of the all cases.
- Trial name
- NCT06954012
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, Exercise
- Where
- 2 sites in Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Al-Ahliyya Amman University
Hamstring Injury
Comparison of Trunk Muscle Performance Between Sprinters With and Without Hamstring Strain Injury History
The aim of this study is to: 1. Compare trunk muscle performance between sprinters with and without HSI history 2. Investigate whether running speed influences the differences on trunk muscle activity between these two groups
- Trial name
- NCT06089681
- Where
- Taiwan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Traumatic Brain Injury, Post-traumatic Epilepsy
Transforming Research and Clinical Knowledge in Traumatic Brain Injury Epileptogenesis Project (TRACK-TBI EPI)
The overarching goal of this study is to improve understanding of the long-range natural history of TBI and post-traumatic epilepsy (PTE) by extending follow-up of a previously enrolled cohort (TRACK-TBI) beyond the first 12…
- Trial name
- NCT05823766
- Testing
- In-Person Outcome Assessment, 3T Magnetic Resonance Imaging (MRI), Clinical Visit
- Where
- 9 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Concussion, Mild
Sex and Age Ultrasound Response to Differential Jugular Vein Pressure
Clinical trials have suggested that this device is effective in mitigating changes in brain structure and function in athlete populations.
- Trial name
- NCT03017937
- Testing
- Q-collar
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Spinal Cord Injuries, Stroke
Wheelchair Cushion Comparison Study: SAFETY
Purpose: To examine the safety of the use of two wheelchair cushions for healthy individuals with intact sensation and individuals post stroke and spinal cord injury with impaired sensation.
- Conditions
- Spinal Cord Injuries, Stroke, Healthy Adults
- Trial name
- NCT03430375
- Testing
- Alternating air wheelchair cushion, Static air cushion
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Carpal Tunnel Syndrome, Anesthesia, Local
Ultrasound-guided Peripheral Nerve Block Versus Forearm Bier's Block in Patients Undergoing Carpal Tunnel Release
By means of an observer-blinded, randomized controlled trial, the analgesic efficacy of the forearm intravenous regional anesthesia and the ultrasound guided peripheral nerve block will be investigated in patients undergoing…
- Trial name
- NCT03411551
- Testing
- regional anesthesia
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jessa Hospital
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