Clinical trials: Injury Leg
Anterior Cruciate Ligament Tear
Anterior Cruciate Ligament (ACL) Reconstruction: Single Bundle Versus Double Bundle
ACL tear is a common injury among athletes. The recommended treatment includes reconstruction of the ligament. The common reconstruction technique is single bundle reconstruction.
- Trial name
- NCT01025895
- Testing
- acl reconstruction - double bundle technique, acle reconstruction - single bundle technique
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center
Femur Fracture, Femur Fracture Intertrochanteric
THP Hip Fracture Plating System Study
The objective of this study is to systematically document the clinical outcomes of THP Hip Fracture Plating System when used to treat intracapsular and intertrochanteric fractures.
- Conditions
- Femur Fracture, Femur Fracture Intertrochanteric, Garden Grade I Subcapital Fracture of Femoral Neck, Garden Grade II Subcapital Fracture of Femoral Neck
- Trial name
- THP (NCT03870477)
- Testing
- THP Hip Fracture Plating System with telescoping lag screws
- Where
- 3 sites in United States
- Volunteers
- 1 people
- Sponsor
- Zimmer Biomet
Arthroplasty, Replacement, Knee, Knee Injuries
ALGRX 4975 After Total Knee Replacement
ALGRX 4975 or placebo will be dripped onto the cut muscles and soft tissues before the end of surgery for total replacement of the knee.
- Trial name
- NCT00132392
- Testing
- ALGRX 4975
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AlgoRx Pharmaceuticals
Tibial Fractures
Immobilization Versus Observation in Children With Toddler's Fractures: a Prospective Randomized Controlled Trial
Toddler's fractures of the tibia are by definition non-displaced and of a stable pattern. Children have thickened periosteum compared with adults, which therefore may impart stability to the fracture without the need for…
- Trial name
- NCT01926795
- Testing
- Short leg cast, No Immobilization
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Prisma Health-Upstate
Hip Fractures
Impact of "ASAP" Multidisciplinary Optimization Care Protocol on Clinical Outcome in Elderly Inpatients for Hip Fracture
To compare the impact of ASAP protocol (geriatric advice, early surgery, loco-regional anesthesia and pharmacological adaptation) on elderly patients with hip fracture and clinical outcome.
- Trial name
- NCT04771364
- Testing
- ASAP care's protocol
- Where
- Belgium
- Volunteers
- 800 people
- Sponsor
- University of Liege
Knee Injuries, Knee Osteoarthritis
Walking Gait Biomechanics Following Knee Joint Effusion
The purpose of this study is to determine the sensitivity of a wearable sensor to detect changes in knee joint loading using an experimental knee joint effusion as a model for a common clinical physiological alteration in joint…
- Trial name
- NCT03805464
- Testing
- Knee Joint Effusion
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Duke University
Anterior Cruciate Ligament Injuries, Knee Injuries
Graft Type and Outcomes After ACL Reconstruction in Female Athletes
This prospective multicenter cohort study aims to compare clinical and functional outcomes between hamstring tendon and quadriceps tendon autografts in anterior cruciate ligament (ACL) reconstruction in female athletes.
- Trial name
- LCA-WOMEN (NCT07722104)
- Testing
- Hamstring tendon autograft ACL reconstruction, Quadriceps tendon autograft ACL reconstruction
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Venous Leg Ulcer (VLU)
ConvaVAC™ Ag+ Negative Pressure Wound Therapy System in Chronic Wounds
Purpose of this study is to learn more about how safe and effective the ConvaVAC™ Ag+ wound therapy system is in treating certain types of long-lasting wounds, called chronic wounds.
- Trial name
- ConvaVAC VLU (NCT07342049)
- Testing
- ConvaVAC™ Ag+ Negative Pressure Wound Therapy System
- Where
- 7 sites in Chile, United Kingdom
- Volunteers
- 87 people
- Sponsor
- ConvaTec Inc.
Femur Fracture
Intramedullary Nailing of the Femur:Trochanteric vs Piriformis Starting Portals
This project is designed to determine whether or not the trochanteric insertion portal will show any difference when compared with the piriformis fossa portal in terms of pain and strength of the hip abductor muscles, while…
- Trial name
- TROCHNAIL (NCT00593333)
- Testing
- Antegrade Intramedullary Nail, Trigen Trochanteric Femoral Nail
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Alabama at Birmingham
Skin Laceration, Skin Abrasion
Retrospective, Observationnal Study to Investigate Procedural Analgesia Delivered to Patients With Lacerations, Abrasions, Burns and Leg Ulcers.
The main part of the study is a retrospective analysis of 200 reports concerning patients with skin wounds and injuries : 50 consecutive patient reports dealing with skin lacerations 50 consecutive patient reports dealing with…
- Conditions
- Skin Laceration, Skin Abrasion, Skin Burn, Leg Ulcer
- Trial name
- APPABU (NCT07350811)
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Versailles Hospital
Fractured Neck of Femur
10 Year Review of the Experience of the PFNA ,TFNA the Affixus Nail
The aim of this study was to investigate the clinical effects of design changes from the use of three different IM nail designs in the management of extracapsular hip fractures.
- Trial name
- NCT03493893
- Testing
- Intermedullary nail
- Volunteers
- 800 people
- Sponsor
- Princess Alexandra Hospital, Brisbane, Australia
Surgical Wound Infection, Coronary Artery Bypass
Ultrasound to Prevent Leg Wound Complications in Heart Bypass.
The long saphenous vein is traditionally harvested for use as a conduit in coronary artery bypass grafting surgery. Currently, the long saphenous vein is not imaged prior to surgery.
- Trial name
- NCT02307084
- Testing
- Ultrasound imaging of the long saphenous vein
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- University Hospitals Bristol and Weston NHS Foundation Trust
Hip Fractures
Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion
Tranexamic Acid (TXA) is an antifibrolytic medication used in total hip and knee arthroplasty to reduce the need for intraoperative and postoperative blood transfusions.
- Trial name
- NCT03063892
- Testing
- Tranexamic Acid (TXA), Saline solution
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Gregory M Georgiadis MD
Tibial Fractures
Stem Cells and Tibial Fractures
The aim of this trial is to determine the safety and tolerability of expanded autologous progeny of an adult CD34+ (haemopoietic) stem cell subset when infused directly into the tibial artery of patients with recent tibial…
- Trial name
- STIF (NCT00632034)
- Testing
- CD34+ haemopoietic stem cells
- Where
- United Kingdom
- Sponsor
- Imperial College London
Anterior Cruciate Ligament Rupture, Acute Pain
Femoral Triangle + IPACK Blocks for ACL Reconstruction Analgesia
An adequate balance between analgesia and motor function is an essential requirement to facilitate functional recovery and early discharge after anterior cruciate ligament (ACL) reconstruction surgery. Proximal nerve blocks (i.e.
- Conditions
- Anterior Cruciate Ligament Rupture, Acute Pain, Pain, Postoperative, Knee Injuries
- Trial name
- NCT05068063
- Testing
- Bupivacaine Injection, normal Saline
- Where
- 2 sites in Chile
- Volunteers
- 48 people
- Sponsor
- University of Chile
Tibial Fractures, Femoral Fractures
Distal Locking Using an Electromagnetic Field Guided Computer Based Real Time System for Orthopaedic Trauma Patients
Hypothesis: Utilization of the "wand" method will enhance improvements in drill placement, locking nail placement during tibia and femur fracture repairs, and offer less radiation exposure and less operative time.
- Trial name
- Sure Shot (NCT01183078)
- Testing
- free-hand, Wand technique
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Wake Forest University Health Sciences
Diabetic Foot, Chronic Foot Ulcer
Randomized Clinical Study Comparing SynPath to Standard of Care in Treatment of Chronic Diabetic Foot Ulcers
The study will evaluate the efficacy of SynPath™, a synthetic dermal matrix, in the treatment of diabetic foot ulcers in subjects with diabetes mellitus versus Standard of Care treatment.
- Conditions
- Diabetic Foot, Chronic Foot Ulcer, Wound Healing, Foot Ulcer
- Trial name
- DFUs (NCT05506215)
- Testing
- SynPath Acellular Dermal Matrix plus Off-loading Device, Wound Dressing composed of 90% collagen and 10% Alginate plus Off-loading Device
- Where
- 7 sites in United States
- Volunteers
- 25 people
- Sponsor
- PolyNovo Biomaterials Pty Ltd.
Hip Fracture, Vertebral Fracture
Norwegian Capture the Fracture Initiative
The main aim is to assess the effectiveness of introducing a standardized intervention program for treatment of patients with a fragility fracture as measured by changes in the fracture rates and the mortality.
- Conditions
- Hip Fracture, Vertebral Fracture, Other Low-trauma Fracture
- Trial name
- NoFRACT (NCT02536898)
- Testing
- Fracture Liaison Service, Current treatment
- Where
- 7 sites in Norway
- Volunteers
- 94,260 people
- Sponsor
- Oslo University Hospital
Arthralgia, Trouble Balancing
Even-Up to Minimize Secondary Site Pain For Ankle Fracture
Evaluating impact of use of Even-Up shoe wear device for patients treated in CAM boot walker for an ankle fracture. Randomized controlled trial, randomizing patients into control group with boot treatment only versus boot…
- Trial name
- NCT04164563
- Testing
- Even-Up
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Knee Injuries
Knee Nerve Cryoneurolysis and Impact on Pain After Prosthetic Surgery
Interventional, comparative, randomized, controlled study versus standard treatment, in 3 parallel groups, monocentric, aiming to demonstrate the superiority of preoperative cryoneurolysis versus no procedure, in patients…
- Trial name
- Cryogenou (NCT05059535)
- Testing
- standard pain relievers
- Where
- France
- Volunteers
- 52 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
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