Clinical trials: Injury Prevention
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Athletic Injury, Fatigue Recovery
Multimodal Machine Learning for Predicting Reduced Participation in Elite Youth Football
This study protocol describes a prospective longitudinal observational study designed to evaluate the accuracy of machine learning models in predicting the short-term (24-72 h) risk of reduced participation (training modification…
- Trial name
- PREDICTYOUTH (NCT07870460)
- Where
- Czechia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Palacky University
Injury;Sports, Biomechanical Lesions
Effectiveness of Basketball Pre-injury Attack Program to Reduce the Susceptibility of Injury in Youth Basketball Players
Basketball is an impact, coordination-opposition sport with continuous contact among players and it is considered a sport of medium-high injury incidence.
- Conditions
- Injury;Sports, Biomechanical Lesions, Musculoskeletal Injury, Sports Physical Therapy
- Trial name
- DPL2 (NCT05256186)
- Testing
- Basketball Pre-injury Attack program
- Where
- Spain
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Injury of Hip and Thigh
Analysis of Different Hip Adductors Exercises
Groin injuries present a major problem in sports due to its high frequency, long-lasting symptoms and high risk of re-injury. The most common groin injury is the adductor strain (around two thirds of all groin injuries), while…
- Trial name
- NCT04101786
- Testing
- Hip adductors exercise variations
- Where
- Slovenia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Primorska
Injuries, Flexibility
Effects of the FIFA 11+ on Physical Performance and Injury Prevention in Female Futsal Players
The FIFA 11 + is an injury prevention that has shown to improve physical performance and prevent injuries in male futsal players, however, this injury prevention program has not been tested in female futsal players.
- Conditions
- Injuries, Flexibility, Balance
- Trial name
- NCT05334082
- Testing
- FIFA 11+
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aveiro University
Surgical Site Infection, Colon Surgery
D-PLEX 311: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection
Phase III, Prospective, Multinational, Multicenter, Randomized, Controlled, Two-arm, Double Blind Study to assess Efficacy and Safety of D-PLEX Administered Concomitantly with the Standard of Care (SoC), compared to a SoC treated…
- Conditions
- Surgical Site Infection, Colon Surgery, Abdominal Surgery, Post-Op Infection
- Trial name
- NCT04233424
- Testing
- D-PLEX, Standard of Care (SoC)
- Where
- 62 sites in United States, Bulgaria and 8 more
- Volunteers
- 977 people
- Sponsor
- PolyPid Ltd.
Fall Prevention, Fall Injury
A Multi-domain and Multi-component Falls Intervention Program for Community- Dwelling Older Adults: SAFE-TECH
Background: Falls and fall-related injuries among older adults are a significant health problem that results in injuries, prolonged hospitalisation, reduced mobility, and poorer quality of life.
- Trial name
- SAFE-TECH (NCT06102954)
- Testing
- Falls prevention intervention including exercise and educational components
- Where
- Singapore
- Volunteers
- 400 people
- Sponsor
- Duke-NUS Graduate Medical School
Chronic Ankle Instability
Elite Athletes With Chronic Ankle Instability Using Spraino®: A Cohort Study
Fear of re-injury and deficiencies in ankle joint function are common conditions amongst high performance (elite) athletes with chronic ankle instability (CAI), who participate in indoor sports.
- Trial name
- NCT03706729
- Testing
- Spraino
- Where
- 2 sites in Denmark
- Sponsor
- University of Southern Denmark
Keloid
Treatment of Keloid Scar by Autologous Platelet Rich Plasma Obtained With RgenKit-BCT
The aim of this prospective study is to assess the efficacy of autologous Platelet Rich Plasma prepared with RegenKit-BCT in the prevention and the treatment of keloid scars refractory to conventional treatments.
- Trial name
- NCT02922972
- Testing
- Autologous Platelet Rich Plasma obtained with RegenKit®-BCT
- Volunteers
- 15 people
- Sponsor
- Regen Lab SA
Pressure Ulcer
Effectiveness of Freedom Bed Compared to Manual Turning in Prevention of Pressure Injuries in Persons With Limited Mobility Due to Traumatic Brain Injury and/or Spinal Cord Injury.
Observational comparison on Incidence of Pressure Injury between the Freedom Bed Automated Continuous lateral Rotation Therapy System and Manual Caregiver Re-positioning every 2 hours on a standard Hospital Bed.
- Trial name
- NCT03048357
- Testing
- Freedom Bed, Standard hospital bed
- Volunteers
- 8 people
- Sponsor
- Northeast Center for Rehabilitation and Brain Injury
Brain Injury Traumatic Moderate, Brain Injury Traumatic Severe
Biperiden Trial for Epilepsy Prevention
One of the most important neurological consequences following Traumatic Brain Injury (TBI) is the development of post traumatic epilepsy (PTE).
- Conditions
- Brain Injury Traumatic Moderate, Brain Injury Traumatic Severe, Post Traumatic Epilepsy
- Trial name
- BIPERIDEN (NCT04945213)
- Testing
- Biperiden
- Where
- 10 sites in Brazil
- Volunteers
- 312 people
- Sponsor
- Hospital Sirio-Libanes
Sports Injury
Prevention of Injuries in Young Athletics (Track and Field) Athletes
The long-term purpose of an on-going participatory action research program "The KLUB-study" in Sweden, that involves scientists and representatives from all levels of athletics, is to develop a sustainable framework for safe…
- Trial name
- NCT03459313
- Testing
- Active group
- Where
- Sweden
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Trauma, Alcohol Use, Unspecified
Secondary Prevention and Recidivism Reduction in Trauma Patients
The consumption of alcohol and other drugs is one of the main risk factors for traumatism. In addition, patients who have suffered an accident in relation to the consumption of these substances present a high risk of recidivism.
- Conditions
- Trauma, Alcohol Use, Unspecified, Drug Use
- Trial name
- NCT03967262
- Testing
- Brief Motivational Intervention
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Corporacion Parc Tauli
Abdominal Surgery, Colon Surgery
D-PLEX 310: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection
Subjects who are planned to undergo an abdominal (colon) surgery and who will meet the study entry criteria will be randomly divided into 2 groups: for half D-PLEX will be administered concomitantly with the standard of care…
- Conditions
- Abdominal Surgery, Colon Surgery, Post-Op Infection
- Trial name
- NCT03633123
- Testing
- D-PLEX, Standard of Care (SoC)
- Where
- 8 sites in Israel
- Volunteers
- 202 people
- Sponsor
- PolyPid Ltd.
Muscle Weakness
Effect of Sequencing on Outcome Measures
This pilot study will examine the effect of testing order on test outcomes for measures of strength, dynamic balance, and movement quality.
- Trial name
- NCT06445491
- Testing
- Control order, Randomized sequence
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Perianal Abscess, Anal Fistula
Antibiotics After Incision and Drainage to Prevent Fistula Formation After First Episode of Perianal Abscess
The goal of this clinical trial is to learn if antibiotics can prevent the formation of fistula-in-ano after incision and drainage of a first time of perianal abscess in adults.
- Trial name
- RAPID (NCT07704359)
- Testing
- Amoxicillin + Clavulanate, Ciprofloxacin + Metronidazole
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- University of Illinois at Chicago
Concussion, Brain
Neck Strengthening Program for the Prevention or Mitigation of Sports Concussion
Study looks to determine effectiveness of neck strengthening to reduce the incident, duration, and severity of sports related concussion in student athletes.
- Trial name
- PCONS (NCT03237468)
- Testing
- Neck strengthening exercise to prevent concussion
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- CentraCare
Vascular Diseases, Peripheral Vascular Disease
Topical Gentamicin and Vancomycin for Vascular Surgical Site Infection Prophylaxis
Many patients who undergo vascular surgery to improve the blood flow to their legs are at risk of developing an infection in the surgical site and are then at risk of serious complications such as hospital readmission, failure of…
- Conditions
- Vascular Diseases, Peripheral Vascular Disease, Surgical Site Infection, Bypass Complication
- Trial name
- NCT04238923
- Testing
- Topical vancomycin paste (1g vancomycin powder + 4mL sterile saline) and Collatamp G gentamicin-eluting sponge (Azralez Pharmaceuticals; 2.0mg gentamicin sulphate/cm2 to cover wound)
- Volunteers
- 356 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Acute Kidney Injury (Nontraumatic)
Biomarker-guided Implementation of the AKI Bundle
There is no specific therapy for acute kidney injury. It is presumed that supportive measures improve the care and outcome of patients with acute kidney injury.
- Trial name
- PrevAKI-mc (NCT03244514)
- Testing
- Intervention
- Where
- 12 sites in Belgium, Germany and 3 more
- Volunteers
- 280 people
- Sponsor
- University Hospital Muenster
Pressure Ulcer, Pressure Injury
The Use of a Fully Automated Pulsating Support System (CuroCell® A4 CX20) in Pressure Ulcer Prevention and Treatment
Pressure Ulcers are a serious and common problem for residents admitted to long-term care facilities and community care patients.
- Conditions
- Pressure Ulcer, Pressure Injury, Pressure Sore, Pressure Ulcer, Buttock
- Trial name
- NCT04890678
- Testing
- 22 residentsat risk for PU development, 18 residents at least one PU category III-IV in the sacral area
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent