Clinical trials: Innovative Procedures
Metabolic Syndrome
Use of Computers to Prevent Metabolic Syndrome
The objective of the proposed study is to design and evaluate a touch screen computer based multi-factorial intervention to educate individuals at risk of Metabolic syndrome in diverse Indian settings including urban, rural and…
- Trial name
- NCT01713465
- Testing
- Computer based Metabolic Syndrome educational program
- Where
- India
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Public Health
Depression, Anxiety
Understanding the Efficacy of Mobile Apps as Intervention for Depression in Adults When Deployed as Part of Primary Care.
The clinical study is meant to optimize the mobile intervention, to develop a robust implementation plan for the mobile intervention within primary care, and to conduct an effectiveness trial, randomizing 128 participants in…
- Conditions
- Depression, Anxiety, Primary Health Care
- Trial name
- NCT03500536
- Testing
- IntelliCare
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Actualize Therapy
Multiple Sclerosis
Medical Education for Better Multiple Sclerosis Outcomes
The main objectives of this study are: i) To design an educational tool to train physicians in overcome cognitive factors associated with therapeutic inertia.
- Trial name
- EDUCAR MS (NCT03134794)
- Testing
- Educational intervention applying the traffic light system (TLS)
- Where
- 4 sites in Argentina, Canada and 2 more
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Physical Inactivity
Pilot Testing an Innovative Physical Activity Intervention for Parents Attending Their Children's Sport Practices
The intervention aims to increase physical activity, an important health behavior, in a high-risk sample (i.e., Black and Hispanic/Latino mothers).
- Trial name
- NCT05461742
- Testing
- Physical activity intervention
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Brown University
Knee Arthroplasty
Technology Interventions to Improve Outcomes After Knee Replacement
The purpose of this study is to examine the effects of two technology interventions on health outcomes (e.g., physical activity, sedentary behavior, physical function, pain) after knee replacement at 2 and 5 months .
- Trial name
- NCT04482400
- Testing
- NEAT!2, MyKneeGuide
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Doctor-Patient-Communication
RCT Regarding SDM Online Training and Face-to-face SDM Training
Cancer patients often report that they are not included in important treatment decisions. Numerous studies have shown that a training concerning Shared Decision Making (SDM) for physicians can improve this situation.
- Trial name
- NCT02674360
- Testing
- SDM Training
- Where
- 2 sites in Germany
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Human Immunodeficiency Virus (HIV) Infection, HIV Prevention
Empowering Knowledge, Self-Testing & Resilience Through Innovative Methods for HIV
The goal of this study is to learn whether a digital tool can help improve HIV knowledge, self-awareness, and testing among adolescents in Yogyakarta, Indonesia.
- Conditions
- Human Immunodeficiency Virus (HIV) Infection, HIV Prevention, Adolescent Health, Digital Education Interventions
- Trial name
- EKSTRIM (NCT07039682)
- Testing
- Digital HIV Education and Self-Screening (EKSTRIM Model)
- Where
- Indonesia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universitas Sebelas Maret
Type 1 Diabetes
Diabetes Inspired Culinary Education (DICE): Culinary Medicine Intervention for At-Risk Youth With Type 1 Diabetes
Diabetes Inspired Culinary Education (DICE) is an innovative family- and community-based culinary medicine intervention designed to mitigate racial/ethnic and socioeconomic status disparities in the treatment and health outcomes…
- Trial name
- DICE (NCT07084805)
- Testing
- Diabetes Inspired Culinary Education (DICE) - Phase 1, Diabetes Inspired Culinary Education (DICE) - Phase 2
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Chronic Low Back Pain (CLBP)
Assessment of Different Clinical Techniques to Treat Patients With Chronic Low Back Pain
This clinical trial aims to assess the effectiveness of different clinical techniques in treating patients with chronic low back pain (CLBP).
- Trial name
- CLBP (NCT06453291)
- Testing
- NSAIDs (Nonsteroidal Anti-Inflammatory Drugs):, Standard Physical Therapy, Neuromodulation via Dorsal Root Ganglion (DRG):
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Iffat Anwar Medical Complex
Epilepsy, Temporal Lobe, Cognitive Decline
Pre-operative Mapping of the Anterior Temporal Lobe Using Functional MRI Innovative Techniques in in Drug-resistant Epileptic Patients
Anterior temporal epilepsy is the most frequent form of focal epilepsy (more than 50% of focal epilepsies). The epilepsy is drug-resistant when epileptic seizures persist despite antiepileptic treatment (25% of cases).
- Trial name
- CARTA (NCT05339438)
- Testing
- functional MRI
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Healthy Volunteers
Construction of a Reference Corridor to Assess the Value of Combining Innovative Morphological and Functional Analysis Techniques in Pediatric Patient Care Based on Different Pathological Models
Reference motion analysis systems require a dedicated, specific laboratory environment, with self-reflective markers placed on anatomical points by trained personnel, limiting gait analysis to specific pathologies.
- Trial name
- IMoFARP (NCT07251634)
- Testing
- Markerless gait analysis
- Where
- France
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neonatal Asphyxia
Randomized Cluster Trial on Innovative and Standard Strategies for Neonatal Resuscitation Training (RCPNEOPERU Project)
Background: About 10% of all newborns may have difficulty breathing and require support by trained personnel. In Peru, 90% of deliveries occur in health facilities; however there is not a national neonatal resuscitation and…
- Trial name
- RCPNEOPERU (NCT03210194)
- Testing
- Standard Neonatal Resuscitation Training, MP-ICT Neonatal Resuscitation Training
- Where
- Peru
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidad Peruana Cayetano Heredia
To Assess the Bone Healing in Fracture Mandible Defects
COMPARATIVE ANALYSIS OF INNOVATIVE BONE HEALING TECHNIQUES
the study intends to observe the outcome of interventions (concentrated growth factor with autograft and xenograft) used to expedite bone healing and adaptation with minimal side effects.
- Trial name
- NCT05480631
- Testing
- autograft, autograft with addition of concenterated growth factor, xenograft with concentrated growth factor
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Homeless Persons
Improving Productive Community Integration in Homeless-experienced Veterans
The VA has been focused on reducing the number of homeless Veterans nationally. However, it has been very difficult to increase the level of productive activities--including work, school, and training--for homeless-experienced…
- Trial name
- MI-CBT (NCT07388641)
- Testing
- Motivational Interviewing and Cognitive Behavioral Therapy, Healthy Behavior Training
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cardiometabolic Health
Cardioprotective Properties of Vegan Burger
Several studies over the last decades have demonstrated the important role of nutrition in the development of chronic diseases, such as cardiovascular disease and cancer.
- Trial name
- VeganBurger (NCT05582720)
- Testing
- Conventional burger, Vegan burger
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Caregiver Burden, Dementia
Mobile App Intervention for Informal Dementia Caregivers
Informal caregivers of persons with dementia (PWD) usually experience elevated levels of caregiving burden and potential depression.
- Conditions
- Caregiver Burden, Dementia, Digital Health
- Trial name
- NCT05551533
- Testing
- Kampung Care App
- Where
- Singapore
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Institute of Mental Health, Singapore
Tobacco Cessation
Addressing Tobacco Use Disparities in Rural Older Adults Through an Innovative Mobile Phone Intervention
The purpose of this study is to evaluate the feasibility, acceptability and preliminary efficacy of a Scheduled Gradual Reduction (SGR) intervention via SMS (short message service) text messaging plus SMS Support Messages in…
- Trial name
- NCT02510716
- Testing
- SGR, Support message only
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Normobaric Hypoxia, Hypoventilation
"Living Low - Training High" Methods and Physiological Responses in Well-trained Swimmers
To overcome the lack of knowledge regarding the impact of different "living low, training high" methods on swimming performance, a 4-week intervention will be carried out to determine and compare the effects of three Repeated…
- Conditions
- Normobaric Hypoxia, Hypoventilation, Normoxia
- Trial name
- NCT06253039
- Testing
- Repeated sprint
- Where
- Portugal
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Faculdade de Motricidade Humana
Esophageal Neoplasms
Innovative MRI Techniques to Improve Treatment Stratification of Patients With Esophageal Cancer
The current standard treatment of resectable esophageal cancer consists of neoadjuvant chemoradiation followed by resection. However, some patients develop recurrent disease despite chemoradiation and additional (systemic)…
- Trial name
- IMPROVE (NCT02253602)
- Testing
- Ferumoxytol
- Where
- Netherlands
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Smoking
Trial of An Innovative Smartphone Intervention for Smoking Cessation
The goal of this study is to determine whether the novel smartphone app (SmartQuit) provides higher quit rates than the current standard smoking cessation app.
- Trial name
- NCT02724462
- Testing
- Smartphone-delivered Intervention (SmartQuit), : Smartphone-delivered Intervention (Standard of care app)
- Where
- United States
- Volunteers
- 2,503 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center