Clinical trials: Insemination
Subfertility
Does Hormonal Luteal Support After Intra-uterine Insemination (IUI) Increase the Pregnancy Rate?
A randomized study to investigate if hormonal luteal support after intra-uterine insemination (IUI) in ovulation induction cycles with human menopausal gonadotropin increases the pregnancy rate
- Trial name
- NCT00700492
- Testing
- progesterone
- Where
- Belgium
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Preeclampsia, Pregnancy Complications
The Correlation Between Immunological Reaction of the Seminal Fluid in the Mother's Blood and Pregnancy Complications
It is known that if there isn't an efficient exposure to the paternal antigens before conception, there is an increased risk for the pre-eclampsia (PE) cascade and other pregnancy complications to take place.
- Conditions
- Preeclampsia, Pregnancy Complications, Insemination; Complication, Immune Tolerance
- Trial name
- NCT04314518
- Where
- 2 sites in Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility, Fertility Disorders
Live Birth Rate After Sperm Selection Using ZyMōt Multi (850µL) Device for Intra Uterine Insemination
This single centre interventional pilot randomized control study intends to compare two methods of sperm preparation for couples referred for Intra Uterine Insemination (IUI) procedure.
- Trial name
- FERTINSEM (NCT06144268)
- Testing
- ZyMōt Multi (850µL), Density Gradient Centrifugation
- Where
- Belgium
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility
Optimal Timing of Intrauterine Insemination (IUI) When Utilizing Superovulation Combined With GnRH Antagonists
The timing of IUI following ovulation induction has been the subject of many studies and a consensus has developed that a single insemination approximately thirty-six hours after ovulation induction is sufficien.
- Trial name
- NCT00675142
- Testing
- Intrauterine Insemination
- Where
- Israel
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Fertility
Human Sperm Markers of Cryodamage Resistance
Sperm freezing has been employed for decades for male fertility preservation in cases of foreseeable or unexpected loss of fertility to guarantee future paternity, and also as a complement of assisted reproduction techniques.
- Trial name
- NCT02535377
- Testing
- Sperm cryopreservation
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI Alicante
Music Therapy
Nurse-Led Staged Art Therapy Effects on Psychological Distress and Pregnancy Outcomes in AIH: RCT
Music therapy is a comprehensive therapy that integrates musicology, psychology and medicine. It is an application and development outside the field of traditional art appreciation and aesthetics .
- Trial name
- NCT07356830
- Testing
- music therapy
- Where
- China
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Infertility Unexplained
Comparison of Recombinant Follicle Stimulating Hormone and the Combination of Recombinant Follicle Stimulating Hormone With Clomiphene Citrate in Stimulated Intrauterine Insemination Cycles
The aim of study is to evaluate the results of two different protocols for ovulation induction during IUI cycles. All patients undergo IUI cycles are randomly divided in to two groups.
- Trial name
- NCT05670795
- Testing
- Recombinant Follicle Stimulating Hormone, Recombinant Follicle Stimulating Hormone and Clomiphene Citrate
- Where
- Turkey (Türkiye)
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Spontaneous Triggering of Ovulation vs. Administration of Human Chorionic Gonadotropin in Patients Undergoing IUI
HCG Versus Spontaneous LH in Intrauterine Insemination (IUI ) Cycles
We recently reported the superiority of the natural cycle to a natural cycle controlled by the administration of human chorionic gonadotropin (hCG) for planning the frozen-thawed embryo transfer cycles, demonstrating a probable…
- Trial name
- NCT01414673
- Testing
- HCG
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Insemination
EVIE-Study: Slow Release Insemination Versus Standard Intrauterine Insemination Study
Overall Study Design and Plan Description The study will be conducted on women with fertility difficulties who are designated for intrauterine insemination treatment (IUI).
- Trial name
- EVIE (NCT02315040)
- Testing
- EVIE, Standard Intrauterine Insemination
- Where
- 12 sites in Austria, France and 2 more
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Primary Infertility
Analysis of Lipid Profiles in Samples Sperm and Seminal Plasma Under Artificial Insemination
Identify, by Lipidomics approaches, biochemical markers of fertility / infertility in sperm and seminal plasma linking the success or failure of the artificial insemination (IUI)
- Trial name
- NCT02704936
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- IVI Bilbao
Infertility
Double and Single Intrauterine Insemination In Controlled Ovarian Stimulation (COH) Cycles With Multifollicular Development
Our hypothesis is double insemination will improve pregnancy rates in coh cycles with more than one dominant follicles (>16mm).
- Trial name
- NCT00993902
- Testing
- Intrauterine insemination (single), Double intrauterine insemination
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Baskent University
Infertility Unexplained, Infertility, Male
Comparison of the Effect of Microchip and Density Gradient Methods in Intrauterine Insemination Cycles
Microfluidic chips are one of the methods of sperm separation to eliminate DNA fragmentation in sperm. It is thought that the separation of sperm by centrifugation in the classical gradient density (Percoll) method used in sperm…
- Trial name
- NCT04144244
- Testing
- MicroFluidic Sperm Sorting Chips, Gradient-Density Centrifugation
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Cervical Cap Insemination
Human Factors Usability Study of Ib2C Conception System
The purpose of this study is to obtain subjective feedback in a home use environment regarding usability and ease of use of the applicator and conception cap and the instructions for use.
- Trial name
- NCT01564940
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Rinovum Women's Health, Inc.
Infertilities
Comparison of the Efficiency of Intra-uterine Insemination and in Vitro Fertilization in Women Over 37 Years
As age increases the chances for a woman to become pregnant decrease as well spontaneously as through assisted reproductive technologies (ART).
- Trial name
- AMPAGE (NCT02001870)
- Testing
- In Vitro Fecundation (IVF), Intra Uterine Insemination (IUI)
- Where
- 12 sites in France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Infertility, Unexplained Infertility
Uterine Scratching in Intra-Uterine Insemination
This study will evaluate the potential benefits of uterine injury during the follicular phase of an intra-uterine insemination cycle on the rate of ongoing pregnancy during the first trimester ultrasound.
- Trial name
- NCT03828786
- Testing
- Endometrial scratching
- Where
- Canada
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- Clinique Ovo
Infertility, Pregnancy
The Effect of Pre-washing the Insemination Catheter on Pregnancy Outcome
The investigators hypothesize that washing the insemination catheter prior to performing the IUI (intrauterine insemination) will improve the pregnancy outcome in IUI cycles when compared to controls (without pre-washing the…
- Trial name
- NCT02445092
- Testing
- washing the insemination catheter with sperm washing media
- Where
- Canada
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Fertility Disorders, Fertility Issues
Menstrual Phase Endometrial Scratch in IUI Cycles
Patients undergoing treatment with intrauterine insemination (IUI) will be randomized to receive an endometrial scratch or sham procedure during the menstrual phase of the treatment cycle.
- Trial name
- NCT04641598
- Testing
- Endometrial Scratch
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Infertility, Spermatozoa
Ejaculatory Abstinence in IUI Cycles
Intrauterine insemination (IUI) combined with ovarian stimulation, has been an extensively used procedure for the treatment of patients with unexplained infertility.
- Conditions
- Infertility, Spermatozoa, Reproductive Disorder
- Trial name
- NCT04361292
- Testing
- INTRAUTERINE INSEMINATION
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Infertility
IUI Schedule in Cases of High Progesterone
Intrauterine insemination (IUI) combined with ovarian stimulation protocols has become one of the first alternative treatment against infertility, although results in gestational terms are highly variable, ranging between 10% and…
- Trial name
- IAD-P4 (NCT02447588)
- Testing
- IAD at 36 hours, IAD at 24 hours
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- IVI Madrid